inositol has been researched along with Anankastic Personality in 24 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inositol, a glucose isomer and second messenger precursor, regulates numerous cellular functions and has demonstrated efficacy in obsessive-compulsive disorder (OCD) through mechanisms that remain unclear." | 9.11 | Single photon emission computed tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol. ( Carey, PD; Harvey, BH; Seedat, S; Stein, DJ; Warwick, J, 2004) |
| "Inositol, an isomer of glucose and precursor in the phosphatidylinositol cycle, may be effective in a number of psychiatric disorders, including obsessive-compulsive disorder (OCD)." | 9.09 | Inositol augmentation of serotonin reuptake inhibitors in treatment-refractory obsessive-compulsive disorder: an open trial. ( Seedat, S; Stein, DJ, 1999) |
| "Thirteen patients with obsessive-compulsive disorder completed a double-blind, controlled crossover trial of 18 g/day of inositol or placebo for 6 weeks each." | 9.08 | Inositol treatment of obsessive-compulsive disorder. ( Aviv, A; Belmaker, RH; Fux, M; Levine, J, 1996) |
| "Inositol, a glucose isomer and second messenger precursor, regulates numerous cellular functions and has demonstrated efficacy in obsessive-compulsive disorder (OCD) through mechanisms that remain unclear." | 5.11 | Single photon emission computed tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol. ( Carey, PD; Harvey, BH; Seedat, S; Stein, DJ; Warwick, J, 2004) |
| "Inositol, an isomer of glucose and precursor in the phosphatidylinositol cycle, may be effective in a number of psychiatric disorders, including obsessive-compulsive disorder (OCD)." | 5.09 | Inositol augmentation of serotonin reuptake inhibitors in treatment-refractory obsessive-compulsive disorder: an open trial. ( Seedat, S; Stein, DJ, 1999) |
| "Thirteen patients with obsessive-compulsive disorder completed a double-blind, controlled crossover trial of 18 g/day of inositol or placebo for 6 weeks each." | 5.08 | Inositol treatment of obsessive-compulsive disorder. ( Aviv, A; Belmaker, RH; Fux, M; Levine, J, 1996) |
| "Clinical trials indicate that inositol may be effective in the treatment of patients with depression, panic disorder and obsessive compulsive disorder (OCD), but not in the treatment of patients with schizophrenia, Alzheimer's disease, ADHD or autism." | 4.81 | The effects of inositol treatment in animal models of psychiatric disorders. ( Belmaker, RH; Einat, H, 2001) |
| "Inositol is a simple polyol precursor in a second messenger system important in the brain." | 2.68 | Controlled trials of inositol in psychiatry. ( Levine, J, 1997) |
| "Myo-inositol is an important part of the phosphatidylinositol second messenger system (PI-cycle)." | 2.43 | A review of the possible relevance of inositol and the phosphatidylinositol second messenger system (PI-cycle) to psychiatric disorders--focus on magnetic resonance spectroscopy (MRS) studies. ( Kim, H; McGrath, BM; Silverstone, PH, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (12.50) | 18.2507 |
| 2000's | 10 (41.67) | 29.6817 |
| 2010's | 9 (37.50) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kishi, T | 1 |
| Sakuma, K | 1 |
| Iwata, N | 1 |
| Kosová, E | 1 |
| Pajuelo, D | 1 |
| Fajnerová, I | 1 |
| Greguš, D | 1 |
| Brunovský, M | 1 |
| Stopková, P | 1 |
| Škoch, A | 1 |
| Fürstová, P | 1 |
| Španiel, F | 1 |
| Horáček, J | 1 |
| Parmar, A | 1 |
| Sharan, P | 1 |
| Khandelwal, SK | 1 |
| Agarwal, K | 1 |
| Sharma, U | 1 |
| Jagannathan, NR | 1 |
| Weber, AM | 1 |
| Soreni, N | 1 |
| Stanley, JA | 1 |
| Greco, A | 1 |
| Mendlowitz, S | 1 |
| Szatmari, P | 1 |
| Schachar, R | 1 |
| Mannasis, K | 1 |
| Pires, P | 1 |
| Swinson, R | 1 |
| Noseworthy, MD | 1 |
| Tükel, R | 1 |
| Aydın, K | 1 |
| Ertekin, E | 1 |
| Özyıldırım, SŞ | 1 |
| Taravari, V | 1 |
| Ortiz, AE | 1 |
| Ortiz, AG | 1 |
| Falcon, C | 1 |
| Morer, A | 1 |
| Plana, MT | 1 |
| Bargalló, N | 1 |
| Lázaro, L | 1 |
| Park, SE | 1 |
| Choi, NG | 1 |
| Jeong, GW | 1 |
| Ljungberg, M | 1 |
| Nilsson, MKL | 1 |
| Melin, K | 1 |
| Jönsson, L | 1 |
| Carlsson, A | 2 |
| Forssell-Aronsson, E | 1 |
| Ivarsson, T | 1 |
| Carlsson, M | 1 |
| Starck, G | 1 |
| Kinrys, G | 1 |
| Coleman, E | 1 |
| Rothstein, E | 1 |
| Fan, Q | 1 |
| Tan, L | 1 |
| You, C | 1 |
| Wang, J | 1 |
| Ross, CA | 1 |
| Wang, X | 1 |
| Zhang, T | 1 |
| Li, J | 1 |
| Chen, K | 1 |
| Xiao, Z | 1 |
| Camfield, DA | 1 |
| Sarris, J | 1 |
| Berk, M | 1 |
| O'Neill, J | 1 |
| Gorbis, E | 1 |
| Feusner, JD | 1 |
| Yip, JC | 1 |
| Chang, S | 1 |
| Maidment, KM | 1 |
| Levitt, JG | 1 |
| Salamon, N | 1 |
| Ringman, JM | 1 |
| Saxena, S | 1 |
| Carey, PD | 1 |
| Warwick, J | 1 |
| Harvey, BH | 4 |
| Stein, DJ | 5 |
| Seedat, S | 4 |
| Rosenberg, DR | 1 |
| Mirza, Y | 1 |
| Russell, A | 1 |
| Tang, J | 1 |
| Smith, JM | 1 |
| Banerjee, SP | 1 |
| Bhandari, R | 1 |
| Rose, M | 1 |
| Ivey, J | 1 |
| Boyd, C | 1 |
| Moore, GJ | 1 |
| Kim, H | 1 |
| McGrath, BM | 1 |
| Silverstone, PH | 1 |
| Scherk, H | 1 |
| Backens, M | 1 |
| Schneider-Axmann, T | 1 |
| Kraft, S | 1 |
| Kemmer, C | 1 |
| Usher, J | 1 |
| Reith, W | 1 |
| Falkai, P | 1 |
| Meyer, J | 1 |
| Gruber, O | 1 |
| Yücel, M | 1 |
| Wood, SJ | 1 |
| Wellard, RM | 1 |
| Harrison, BJ | 1 |
| Fornito, A | 1 |
| Pujol, J | 1 |
| Velakoulis, D | 1 |
| Pantelis, C | 1 |
| Fux, M | 1 |
| Levine, J | 2 |
| Aviv, A | 1 |
| Belmaker, RH | 2 |
| Einat, H | 1 |
| Scheepers, A | 1 |
| Brand, L | 1 |
| Brink, CB | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inositol for Comorbid Anxiety in Children and Adolescents With Bipolar Disorder[NCT02811133] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2023-08-31 | Withdrawn (stopped due to Funding terminated) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 reviews available for inositol and Anankastic Personality
| Article | Year |
|---|---|
Mitochondrial modulators for obsessive-compulsive and related disorders: a systematic review and meta-analysis.
Topics: Acetylcysteine; Adult; Double-Blind Method; Female; Humans; Inositol; Lithium; Male; Obsessive-Compu | 2022 |
Natural remedies for anxiety disorders: potential use and clinical applications.
Topics: Anti-Anxiety Agents; Antioxidants; Anxiety Disorders; Humans; Hypericum; Inositol; Kava; Melatonin; | 2009 |
Nutraceuticals in the treatment of obsessive compulsive disorder (OCD): a review of mechanistic and clinical evidence.
Topics: 5-Hydroxytryptophan; Acetylcysteine; Dietary Supplements; Glycine; Humans; Hypericum; Inositol; Obse | 2011 |
A review of the possible relevance of inositol and the phosphatidylinositol second messenger system (PI-cycle) to psychiatric disorders--focus on magnetic resonance spectroscopy (MRS) studies.
Topics: Bipolar Disorder; Feeding and Eating Disorders; Humans; Inositol; Magnetic Resonance Spectroscopy; M | 2005 |
The effects of inositol treatment in animal models of psychiatric disorders.
Topics: Affect; Animals; Arousal; Depressive Disorder; Disease Models, Animal; Humans; Inositol; Mental Diso | 2001 |
Defining the neuromolecular action of myo-inositol: application to obsessive-compulsive disorder.
Topics: Brain; Humans; Inositol; Obsessive-Compulsive Disorder; Phosphatidylinositols; Signal Transduction | 2002 |
4 trials available for inositol and Anankastic Personality
| Article | Year |
|---|---|
Single photon emission computed tomography (SPECT) in obsessive-compulsive disorder before and after treatment with inositol.
Topics: Cerebrovascular Circulation; Female; Humans; Inositol; Male; Obsessive-Compulsive Disorder; Radiopha | 2004 |
Inositol treatment of obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Double-Blind Method; Female; Humans; Inositol; Male | 1996 |
Controlled trials of inositol in psychiatry.
Topics: Adult; Alzheimer Disease; Depressive Disorder; Double-Blind Method; Female; Humans; Inositol; Male; | 1997 |
Inositol augmentation of serotonin reuptake inhibitors in treatment-refractory obsessive-compulsive disorder: an open trial.
Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Humans; Inositol; Male; Middle Aged; Obsessive | 1999 |
14 other studies available for inositol and Anankastic Personality
| Article | Year |
|---|---|
Spectroscopic abnormalities in the pregenual anterior cingulate cortex in obsessive-compulsive disorder using proton magnetic resonance spectroscopy: a controlled study.
Topics: Aspartic Acid; Creatine; Glutamine; Gyrus Cinguli; Humans; Inositol; Magnetic Resonance Imaging; Obs | 2023 |
Brain neurochemistry in unmedicated obsessive-compulsive disorder patients and effects of 12-week escitalopram treatment:
Topics: Adolescent; Adult; Case-Control Studies; Caudate Nucleus; Choline; Citalopram; Female; Follow-Up Stu | 2019 |
Proton magnetic resonance spectroscopy of prefrontal white matter in psychotropic naïve children and adolescents with obsessive-compulsive disorder.
Topics: Adolescent; Child; Choline; Creatine; Female; Humans; Inositol; Magnetic Resonance Spectroscopy; Mal | 2014 |
Proton magnetic resonance spectroscopy in obsessive-compulsive disorder: evidence for reduced neuronal integrity in the anterior cingulate.
Topics: Adult; Aspartic Acid; Caudate Nucleus; Choline; Creatine; Female; Gyrus Cinguli; Humans; Inositol; M | 2014 |
1H-MRS of the anterior cingulate cortex in childhood and adolescent obsessive-compulsive disorder: a case-control study.
Topics: Adolescent; Aspartic Acid; Case-Control Studies; Child; Female; Glutamic Acid; Glutamine; Gyrus Cing | 2015 |
Metabolic abnormality in the right dorsolateral prefrontal cortex in patients with obsessive-compulsive disorder: proton magnetic resonance spectroscopy.
Topics: Adult; Aspartic Acid; Brain; Choline; Female; Glutamic Acid; Glutamine; Humans; Inositol; Lactic Aci | 2017 |
1H magnetic resonance spectroscopy evidence for occipital involvement in treatment-naive paediatric obsessive-compulsive disorder.
Topics: Adolescent; Aspartic Acid; Brain; Child; Choline; Female; Humans; Inositol; Male; Obsessive-Compulsi | 2017 |
Increased N-Acetylaspartate/creatine ratio in the medial prefrontal cortex among unmedicated obsessive-compulsive disorder patients.
Topics: Adolescent; Adult; Aspartic Acid; Choline; Creatine; Diagnostic and Statistical Manual of Mental Dis | 2010 |
Effects of intensive cognitive-behavioral therapy on cingulate neurochemistry in obsessive-compulsive disorder.
Topics: Adult; Analysis of Variance; Aspartic Acid; Brain; Choline; Cognitive Behavioral Therapy; Dipeptides | 2013 |
Reduced anterior cingulate glutamatergic concentrations in childhood OCD and major depression versus healthy controls.
Topics: Adolescent; Aspartic Acid; Child; Choline; Creatine; Depressive Disorder, Major; Female; Glutamic Ac | 2004 |
Dopamine transporter genotype influences N-acetyl-aspartate in the left putamen.
Topics: Adult; Aspartic Acid; Bipolar Disorder; Choline; Creatine; Dominance, Cerebral; Dopamine Plasma Memb | 2009 |
Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorder.
Topics: Adult; Aspartic Acid; Biomarkers; Choline; Creatine; Female; Glutamic Acid; Glutamine; Gyrus Cinguli | 2008 |
Inositol in the treatment of trichotillomania and compulsive skin picking.
Topics: Adult; Citalopram; Drug Therapy, Combination; Female; Humans; Inositol; Obsessive-Compulsive Disorde | 2001 |
Chronic inositol increases striatal D(2) receptors but does not modify dexamphetamine-induced motor behavior. Relevance to obsessive-compulsive disorder.
Topics: Animals; Corpus Striatum; Dextroamphetamine; Dopamine Agents; Female; Guinea Pigs; Inositol; Male; M | 2001 |