inositol has been researched along with Amyotrophic Lateral Sclerosis in 5 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To analyze whether survival and disease progression in patients with ALS have changed during the past 20 years." | 1.33 | Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing? ( Appel, SH; Czaplinski, A; Simpson, EP; Yen, AA, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blicher, JU | 1 |
| Eskildsen, SF | 1 |
| Stærmose, TG | 1 |
| Møller, AT | 1 |
| Figlewski, K | 1 |
| Near, J | 1 |
| Weerasekera, A | 1 |
| Peeters, R | 1 |
| Sima, D | 1 |
| Dresselaers, T | 1 |
| Sunaert, S | 1 |
| De Vocht, J | 1 |
| Claeys, K | 1 |
| Van Huffel, S | 1 |
| Van Damme, P | 1 |
| Himmelreich, U | 1 |
| Choi, JK | 1 |
| Küstermann, E | 1 |
| Dedeoglu, A | 1 |
| Jenkins, BG | 1 |
| Carew, JD | 1 |
| Nair, G | 1 |
| Andersen, PM | 1 |
| Wuu, J | 1 |
| Gronka, S | 1 |
| Hu, X | 1 |
| Benatar, M | 1 |
| Czaplinski, A | 1 |
| Yen, AA | 1 |
| Simpson, EP | 1 |
| Appel, SH | 1 |
5 other studies available for inositol and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T.
Topics: Aged; Amyotrophic Lateral Sclerosis; Aspartic Acid; Atrophy; Choline; Creatine; Disease Progression; | 2019 |
Motor cortex metabolite alterations in amyotrophic lateral sclerosis assessed in vivo using edited and non-edited magnetic resonance spectroscopy.
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Disease Progression; Female; Glutathione; Humans; Image | 2019 |
Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Biomarkers; Brain; Creatine; Disease Models, | 2009 |
Presymptomatic spinal cord neurometabolic findings in SOD1-positive people at risk for familial ALS.
Topics: Adult; Amyotrophic Lateral Sclerosis; Aspartic Acid; Case-Control Studies; Choline; Creatine; Cross- | 2011 |
Slower disease progression and prolonged survival in contemporary patients with amyotrophic lateral sclerosis: is the natural history of amyotrophic lateral sclerosis changing?
Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Dipeptides; Disease Progression; Female; Hum | 2006 |