inositol has been researched along with Alcoholism in 14 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex." | 7.11 | Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022) |
| " Having an acquired immune deficiency syndrome (AIDS)-defining event or hepatitis C was associated with higher Cho; lower Cho levels, however, were associated with low thiamine levels and with highly active antiretroviral HIV treatment (HAART)." | 3.80 | Imaging neuroinflammation? A perspective from MR spectroscopy. ( Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM, 2014) |
| "Concentrations of N-acetylaspartate, choline-containing compounds, myo-inositol, and creatine plus phosphocreatine in frontal lobe gray matter and white matter were estimated in eight women and 17 men who were recently detoxified from long-term alcoholism." | 3.72 | Effects of alcoholism and gender on brain metabolism. ( Alhassoon, OM; Brown, GG; Gonzalez, R; Grant, I; Patterson, TL; Schweinsburg, BC; Taylor, MJ; Videen, JS, 2003) |
| "Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex." | 3.11 | Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022) |
| "Mood disorders and Major Depressive Disorder, in particular, appear to be some of the most common psychiatric disorders with a high rate of comorbidity most frequently of anxiety or substance abuse disorders (alcohol use disorder)." | 2.66 | Immunological Disturbances and Neuroimaging Findings in Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) Comorbid Patients. ( Kakanakova, A; Maes, M; Popov, S, 2020) |
| "Posttraumatic stress disorder (PTSD) patients have low cortical concentrations of γ-aminobutyric acid (GABA) and elevated glutamate (Glu) as measured by proton magnetic resonance spectroscopy ((1)H MRS)." | 1.40 | A preliminary examination of cortical neurotransmitter levels associated with heavy drinking in posttraumatic stress disorder. ( Abé, C; Batki, SL; Meyerhoff, DJ; Pennington, DL, 2014) |
| "Recent studies demonstrated that alcohol dependence and excessive alcohol consumption are associated with increased rates of obesity." | 1.36 | Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study. ( Durazzo, TC; Gazdzinski, S; Meyerhoff, DJ; Mon, A, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (14.29) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 3 (21.43) | 2.80 |
| Authors | Studies |
|---|---|
| Grodin, EN | 2 |
| Nieto, SJ | 1 |
| Meredith, LR | 1 |
| Burnette, E | 1 |
| O'Neill, J | 2 |
| Alger, J | 2 |
| London, ED | 1 |
| Miotto, K | 1 |
| Evans, CJ | 1 |
| Irwin, MR | 1 |
| Ray, LA | 2 |
| Burnette, EM | 1 |
| Kakanakova, A | 1 |
| Popov, S | 1 |
| Maes, M | 1 |
| Zahr, NM | 1 |
| Mayer, D | 1 |
| Rohlfing, T | 1 |
| Sullivan, EV | 1 |
| Pfefferbaum, A | 1 |
| Pennington, DL | 1 |
| Abé, C | 1 |
| Batki, SL | 1 |
| Meyerhoff, DJ | 2 |
| Licata, SC | 1 |
| Renshaw, PF | 1 |
| Gazdzinski, S | 1 |
| Durazzo, TC | 1 |
| Mon, A | 1 |
| Schweinsburg, BC | 2 |
| Alhassoon, OM | 2 |
| Taylor, MJ | 2 |
| Gonzalez, R | 1 |
| Videen, JS | 2 |
| Brown, GG | 2 |
| Patterson, TL | 2 |
| Grant, I | 2 |
| NADEAU, G | 1 |
| ROULEAU, Y | 1 |
| DELAGE, J | 1 |
| Viola, A | 1 |
| Nicoli, F | 1 |
| Denis, B | 1 |
| Confort-Gouny, S | 1 |
| Le Fur, Y | 1 |
| Ranjeva, JP | 1 |
| Viout, P | 1 |
| Cozzone, PJ | 1 |
| Zhang, JP | 1 |
| Xia, JM | 1 |
| Sun, GY | 1 |
| Braunová, Z | 1 |
| Kasparová, S | 1 |
| Mlynárik, V | 1 |
| Mierisová, S | 1 |
| Liptaj, T | 1 |
| Tkác, I | 1 |
| Gvozdjáková, A | 1 |
| Berger, F | 1 |
| Pisi, E | 1 |
| Bianchi, FB | 1 |
| Nigro, F | 1 |
2 reviews available for inositol and Alcoholism
| Article | Year |
|---|---|
Immunological Disturbances and Neuroimaging Findings in Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) Comorbid Patients.
Topics: Alcoholism; Anxiety Disorders; Brain; Comorbidity; Cytokines; Depressive Disorder, Major; gamma-Amin | 2020 |
Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction.
Topics: Alcoholism; Animals; Appetite Stimulants; Aspartic Acid; Brain; Choline; Cocaine; Creatine; Glutamic | 2010 |
1 trial available for inositol and Alcoholism
| Article | Year |
|---|---|
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial.
Topics: Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; C-Reactive Protein; Choline; Creatine; Humans; | 2022 |
11 other studies available for inositol and Alcoholism
| Article | Year |
|---|---|
Alcohol Craving and Severity are Associated with Dorsal Anterior Cingulate Choline Levels in Individuals with an Alcohol Use Disorder.
Topics: Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Choline; Craving; Ethanol; Gyrus Cinguli; H | 2023 |
Imaging neuroinflammation? A perspective from MR spectroscopy.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Alcoholism; Antiretroviral Thera | 2014 |
A preliminary examination of cortical neurotransmitter levels associated with heavy drinking in posttraumatic stress disorder.
Topics: Adult; Aged; Alcoholism; Aspartic Acid; Cerebral Cortex; Choline; Comorbidity; Creatine; gamma-Amino | 2014 |
Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Aspartic Acid; Body Mass Index; Brain; Choline; Creatine; | 2010 |
Effects of alcoholism and gender on brain metabolism.
Topics: Adult; Age Factors; Alcoholism; Aspartic Acid; Brain; Creatine; Female; Frontal Lobe; Humans; Inosit | 2003 |
[The fate of the liver in alcoholics. II. Use of lipotropic factors in the treatment of hepatic dysfunction].
Topics: Alcoholics; Alcoholism; Choline; Humans; Inositol; Lipotropic Agents; Liver Diseases; Methionine | 1954 |
High cerebral scyllo-inositol: a new marker of brain metabolism disturbances induced by chronic alcoholism.
Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Biomarkers; Brain; Brain Chemistry; Brain Diseases, Metab | 2004 |
Chronic ethanol inhibits inositol metabolism in specific brain regions.
Topics: Alcoholism; Animals; Brain; Cerebellum; Cerebral Cortex; Ethanol; Hippocampus; Inositol; Male; Mice; | 1997 |
Metabolic changes in rat brain after prolonged ethanol consumption measured by 1H and 31P MRS experiments.
Topics: Adenosine Triphosphate; Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; Astrocytes; Brain; Cho | 2000 |
Chemical pathology in brain white matter of recently detoxified alcoholics: a 1H magnetic resonance spectroscopy investigation of alcohol-associated frontal lobe injury.
Topics: Adult; Alcoholism; Aspartic Acid; Brain; Choline; Creatine; Female; Frontal Lobe; Humans; Inositol; | 2001 |
[Considerations on the therapy of hepatic steatosis].
Topics: Adult; Aged; Alcoholism; Choline; Colitis, Ulcerative; Diabetes Complications; Fatty Liver; Gout; He | 1969 |