Page last updated: 2024-10-19

inositol and Alcohol Abuse

inositol has been researched along with Alcohol Abuse in 14 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Research Excerpts

ExcerptRelevanceReference
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."7.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)
" Having an acquired immune deficiency syndrome (AIDS)-defining event or hepatitis C was associated with higher Cho; lower Cho levels, however, were associated with low thiamine levels and with highly active antiretroviral HIV treatment (HAART)."3.80Imaging neuroinflammation? A perspective from MR spectroscopy. ( Mayer, D; Pfefferbaum, A; Rohlfing, T; Sullivan, EV; Zahr, NM, 2014)
"Concentrations of N-acetylaspartate, choline-containing compounds, myo-inositol, and creatine plus phosphocreatine in frontal lobe gray matter and white matter were estimated in eight women and 17 men who were recently detoxified from long-term alcoholism."3.72Effects of alcoholism and gender on brain metabolism. ( Alhassoon, OM; Brown, GG; Gonzalez, R; Grant, I; Patterson, TL; Schweinsburg, BC; Taylor, MJ; Videen, JS, 2003)
"Ibudilast-treated participants had lower Cho in superior frontal white matter and nominally lower MI in pregenual anterior cingulate cortex."3.11Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial. ( Alger, J; Burnette, E; Evans, CJ; Grodin, EN; Irwin, MR; London, ED; Meredith, LR; Miotto, K; Nieto, SJ; O'Neill, J; Ray, LA, 2022)
"Mood disorders and Major Depressive Disorder, in particular, appear to be some of the most common psychiatric disorders with a high rate of comorbidity most frequently of anxiety or substance abuse disorders (alcohol use disorder)."2.66Immunological Disturbances and Neuroimaging Findings in Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) Comorbid Patients. ( Kakanakova, A; Maes, M; Popov, S, 2020)
"Posttraumatic stress disorder (PTSD) patients have low cortical concentrations of γ-aminobutyric acid (GABA) and elevated glutamate (Glu) as measured by proton magnetic resonance spectroscopy ((1)H MRS)."1.40A preliminary examination of cortical neurotransmitter levels associated with heavy drinking in posttraumatic stress disorder. ( Abé, C; Batki, SL; Meyerhoff, DJ; Pennington, DL, 2014)
"Recent studies demonstrated that alcohol dependence and excessive alcohol consumption are associated with increased rates of obesity."1.36Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study. ( Durazzo, TC; Gazdzinski, S; Meyerhoff, DJ; Mon, A, 2010)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19902 (14.29)18.7374
1990's1 (7.14)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Grodin, EN2
Nieto, SJ1
Meredith, LR1
Burnette, E1
O'Neill, J2
Alger, J2
London, ED1
Miotto, K1
Evans, CJ1
Irwin, MR1
Ray, LA2
Burnette, EM1
Kakanakova, A1
Popov, S1
Maes, M1
Zahr, NM1
Mayer, D1
Rohlfing, T1
Sullivan, EV1
Pfefferbaum, A1
Pennington, DL1
Abé, C1
Batki, SL1
Meyerhoff, DJ2
Licata, SC1
Renshaw, PF1
Gazdzinski, S1
Durazzo, TC1
Mon, A1
Schweinsburg, BC2
Alhassoon, OM2
Taylor, MJ2
Gonzalez, R1
Videen, JS2
Brown, GG2
Patterson, TL2
Grant, I2
NADEAU, G1
ROULEAU, Y1
DELAGE, J1
Viola, A1
Nicoli, F1
Denis, B1
Confort-Gouny, S1
Le Fur, Y1
Ranjeva, JP1
Viout, P1
Cozzone, PJ1
Zhang, JP1
Xia, JM1
Sun, GY1
Braunová, Z1
Kasparová, S1
Mlynárik, V1
Mierisová, S1
Liptaj, T1
Tkác, I1
Gvozdjáková, A1
Berger, F1
Pisi, E1
Bianchi, FB1
Nigro, F1

Reviews

2 reviews available for inositol and Alcohol Abuse

ArticleYear
Immunological Disturbances and Neuroimaging Findings in Major Depressive Disorder (MDD) and Alcohol Use Disorder (AUD) Comorbid Patients.
    Current topics in medicinal chemistry, 2020, Volume: 20, Issue:9

    Topics: Alcoholism; Anxiety Disorders; Brain; Comorbidity; Cytokines; Depressive Disorder, Major; gamma-Amin

2020
Neurochemistry of drug action: insights from proton magnetic resonance spectroscopic imaging and their relevance to addiction.
    Annals of the New York Academy of Sciences, 2010, Volume: 1187

    Topics: Alcoholism; Animals; Appetite Stimulants; Aspartic Acid; Brain; Choline; Cocaine; Creatine; Glutamic

2010

Trials

1 trial available for inositol and Alcohol Abuse

ArticleYear
Effects of ibudilast on central and peripheral markers of inflammation in alcohol use disorder: A randomized clinical trial.
    Addiction biology, 2022, Volume: 27, Issue:4

    Topics: Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; C-Reactive Protein; Choline; Creatine; Humans;

2022

Other Studies

11 other studies available for inositol and Alcohol Abuse

ArticleYear
Alcohol Craving and Severity are Associated with Dorsal Anterior Cingulate Choline Levels in Individuals with an Alcohol Use Disorder.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2023, May-09, Volume: 58, Issue:3

    Topics: Alcohol Drinking; Alcohol-Related Disorders; Alcoholism; Choline; Craving; Ethanol; Gyrus Cinguli; H

2023
Imaging neuroinflammation? A perspective from MR spectroscopy.
    Brain pathology (Zurich, Switzerland), 2014, Volume: 24, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Aged, 80 and over; Alcoholism; Antiretroviral Thera

2014
A preliminary examination of cortical neurotransmitter levels associated with heavy drinking in posttraumatic stress disorder.
    Psychiatry research, 2014, Dec-30, Volume: 224, Issue:3

    Topics: Adult; Aged; Alcoholism; Aspartic Acid; Cerebral Cortex; Choline; Comorbidity; Creatine; gamma-Amino

2014
Body mass index is associated with brain metabolite levels in alcohol dependence--a multimodal magnetic resonance study.
    Alcoholism, clinical and experimental research, 2010, Volume: 34, Issue:12

    Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Aspartic Acid; Body Mass Index; Brain; Choline; Creatine;

2010
Effects of alcoholism and gender on brain metabolism.
    The American journal of psychiatry, 2003, Volume: 160, Issue:6

    Topics: Adult; Age Factors; Alcoholism; Aspartic Acid; Brain; Creatine; Female; Frontal Lobe; Humans; Inosit

2003
[The fate of the liver in alcoholics. II. Use of lipotropic factors in the treatment of hepatic dysfunction].
    Laval medical, 1954, Volume: 19, Issue:1

    Topics: Alcoholics; Alcoholism; Choline; Humans; Inositol; Lipotropic Agents; Liver Diseases; Methionine

1954
High cerebral scyllo-inositol: a new marker of brain metabolism disturbances induced by chronic alcoholism.
    Magma (New York, N.Y.), 2004, Volume: 17, Issue:1

    Topics: Adult; Aged; Alcohol Drinking; Alcoholism; Biomarkers; Brain; Brain Chemistry; Brain Diseases, Metab

2004
Chronic ethanol inhibits inositol metabolism in specific brain regions.
    Alcoholism, clinical and experimental research, 1997, Volume: 21, Issue:4

    Topics: Alcoholism; Animals; Brain; Cerebellum; Cerebral Cortex; Ethanol; Hippocampus; Inositol; Male; Mice;

1997
Metabolic changes in rat brain after prolonged ethanol consumption measured by 1H and 31P MRS experiments.
    Cellular and molecular neurobiology, 2000, Volume: 20, Issue:6

    Topics: Adenosine Triphosphate; Alcohol Drinking; Alcoholism; Animals; Aspartic Acid; Astrocytes; Brain; Cho

2000
Chemical pathology in brain white matter of recently detoxified alcoholics: a 1H magnetic resonance spectroscopy investigation of alcohol-associated frontal lobe injury.
    Alcoholism, clinical and experimental research, 2001, Volume: 25, Issue:6

    Topics: Adult; Alcoholism; Aspartic Acid; Brain; Choline; Creatine; Female; Frontal Lobe; Humans; Inositol;

2001
[Considerations on the therapy of hepatic steatosis].
    Minerva medica, 1969, Aug-29, Volume: 60, Issue:69

    Topics: Adult; Aged; Alcoholism; Choline; Colitis, Ulcerative; Diabetes Complications; Fatty Liver; Gout; He

1969