inositol and Adenoma
inositol has been researched along with Adenoma in 7 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
Adenoma: A benign epithelial tumor with a glandular organization.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, the effects of myo-inositol and dexamethasone on benzo[a]pyrene (B[a]P)-induced pulmonary adenoma formation in female A/J mice was investigated." | 3.68 | Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice. ( Estensen, RD; Wattenberg, LW, 1993) |
| "Inositol uptake was also increased but there was no spontaneous increase of the generation of inositol phosphates and this metabolism could be further activated by TSH." | 1.31 | Characterization of autonomous thyroid adenoma: metabolism, gene expression, and pathology. ( Allory, Y; Carrasco, N; Corvilain, B; Deleu, S; Dumont, JE; Franc, B; Maenhaut, C; Pirson, I; Radulescu, A; Salmon, I; Van Sande, J, 2000) |
Research
Studies (7)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Estensen, RD | 4 |
| Jordan, MM | 1 |
| Wiedmann, TS | 2 |
| Galbraith, AR | 2 |
| Steele, VE | 3 |
| Wattenberg, LW | 4 |
| Zimmerman, CL | 1 |
| Kelloff, GJ | 1 |
| Deleu, S | 1 |
| Allory, Y | 1 |
| Radulescu, A | 1 |
| Pirson, I | 1 |
| Carrasco, N | 1 |
| Corvilain, B | 1 |
| Salmon, I | 1 |
| Franc, B | 1 |
| Dumont, JE | 1 |
| Van Sande, J | 1 |
| Maenhaut, C | 1 |
| Gunning, WT | 1 |
| Kramer, PM | 1 |
| Lubet, RA | 1 |
| Pereira, MA | 1 |
| French, FA | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Influence of Fluticasone Inhalation on Intermediate Markers of Carcinogenesis in the Bronchial Epithelium of a High Risk Population : A Double Blind Placebo-Controlled Randomised Phase II Study[NCT00407264] | Phase 2 | 90 participants | Interventional | 2002-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
7 other studies available for inositol and Adenoma
| Article | Year |
|---|---|
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea | 2004 |
Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice.
Topics: Adenoma; Animals; Benzo(a)pyrene; Dexamethasone; Drug Screening Assays, Antitumor; Drug Therapy, Com | 1993 |
Chemopreventive effects of myo-inositol and dexamethasone on benzo[a]pyrene and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in female A/J mice.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Dexamethasone; Drug Screenin | 1996 |
Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol.
Topics: Adenoma; Administration, Oral; Aerosols; Animals; Anticarcinogenic Agents; Beclomethasone; Benzo(a)p | 2000 |
Characterization of autonomous thyroid adenoma: metabolism, gene expression, and pathology.
Topics: Adenoma; Biological Transport; Gene Expression; Humans; Inositol; Iodides; Ki-67 Antigen; Proto-Onco | 2000 |
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso | 2000 |
The influence of nutritional factors on pulmonary adenomas in mice.
Topics: Adenoma; Animals; Body Weight; Choline; Inositol; Lung Neoplasms; Mice; Mice, Inbred Strains; Niacin | 1977 |