Page last updated: 2024-10-19

inositol and Adenoma

inositol has been researched along with Adenoma in 7 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Adenoma: A benign epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" In the present study, the effects of myo-inositol and dexamethasone on benzo[a]pyrene (B[a]P)-induced pulmonary adenoma formation in female A/J mice was investigated."3.68Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice. ( Estensen, RD; Wattenberg, LW, 1993)
"Inositol uptake was also increased but there was no spontaneous increase of the generation of inositol phosphates and this metabolism could be further activated by TSH."1.31Characterization of autonomous thyroid adenoma: metabolism, gene expression, and pathology. ( Allory, Y; Carrasco, N; Corvilain, B; Deleu, S; Dumont, JE; Franc, B; Maenhaut, C; Pirson, I; Radulescu, A; Salmon, I; Van Sande, J, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Estensen, RD4
Jordan, MM1
Wiedmann, TS2
Galbraith, AR2
Steele, VE3
Wattenberg, LW4
Zimmerman, CL1
Kelloff, GJ1
Deleu, S1
Allory, Y1
Radulescu, A1
Pirson, I1
Carrasco, N1
Corvilain, B1
Salmon, I1
Franc, B1
Dumont, JE1
Van Sande, J1
Maenhaut, C1
Gunning, WT1
Kramer, PM1
Lubet, RA1
Pereira, MA1
French, FA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Influence of Fluticasone Inhalation on Intermediate Markers of Carcinogenesis in the Bronchial Epithelium of a High Risk Population : A Double Blind Placebo-Controlled Randomised Phase II Study[NCT00407264]Phase 290 participants Interventional2002-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

7 other studies available for inositol and Adenoma

ArticleYear
Effect of chemopreventive agents on separate stages of progression of benzo[alpha]pyrene induced lung tumors in A/J mice.
    Carcinogenesis, 2004, Volume: 25, Issue:2

    Topics: Adenoma; Aerosols; Animals; Anti-Inflammatory Agents; Benzo(a)pyrene; Budesonide; Carcinogens; Disea

2004
Studies of chemopreventive effects of myo-inositol on benzo[a]pyrene-induced neoplasia of the lung and forestomach of female A/J mice.
    Carcinogenesis, 1993, Volume: 14, Issue:9

    Topics: Adenoma; Animals; Benzo(a)pyrene; Dexamethasone; Drug Screening Assays, Antitumor; Drug Therapy, Com

1993
Chemopreventive effects of myo-inositol and dexamethasone on benzo[a]pyrene and 4-(methylnitrosoamino)-1-(3-pyridyl)-1-butanone-induced pulmonary carcinogenesis in female A/J mice.
    Cancer research, 1996, Nov-15, Volume: 56, Issue:22

    Topics: Adenoma; Animals; Anticarcinogenic Agents; Benzo(a)pyrene; Carcinogens; Dexamethasone; Drug Screenin

1996
Chemoprevention of pulmonary carcinogenesis by brief exposures to aerosolized budesonide or beclomethasone dipropionate and by the combination of aerosolized budesonide and dietary myo-inositol.
    Carcinogenesis, 2000, Volume: 21, Issue:2

    Topics: Adenoma; Administration, Oral; Aerosols; Animals; Anticarcinogenic Agents; Beclomethasone; Benzo(a)p

2000
Characterization of autonomous thyroid adenoma: metabolism, gene expression, and pathology.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:2

    Topics: Adenoma; Biological Transport; Gene Expression; Humans; Inositol; Iodides; Ki-67 Antigen; Proto-Onco

2000
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso

2000
The influence of nutritional factors on pulmonary adenomas in mice.
    Advances in experimental medicine and biology, 1977, Volume: 91

    Topics: Adenoma; Animals; Body Weight; Choline; Inositol; Lung Neoplasms; Mice; Mice, Inbred Strains; Niacin

1977