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inositol and Adenocarcinoma

inositol has been researched along with Adenocarcinoma in 17 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18."7.76Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010)
"The inositol compounds were administered via the drinking fluid."5.34Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds. ( Liao, J; Lu, GG; Seril, DN; Yang, AL; Yang, GY, 2007)
" In this paper, we extended our work and examined the effects of I3C (70 or 30 micromol/g diet) and MI (56 micromol/g diet) against vinyl carbamate (VC)-induced lung adenocarcinoma by administering the agents from 1 week after the second of two injections of VC until termination of the study at week 18."3.76Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. ( Hecht, SS; Kalscheuer, S; Kassie, F; Ma, L; Matise, I; Melkamu, T; Upadhyaya, P, 2010)
"Concentrations of vitamins, biopterin, free inositol and acid-soluble carnitine were determined in cyclosporine A induced renal adenocarcinoma and uninvaded renal tissue from streptozotocin diabetic rats."3.68Vitamin and micronutrient concentrations in cyclosporine-induced renal tumor from diabetic rats. ( Baker, H; DeAngelis, B; Frank, O; Jyothirmayi, GN; Kabaria, V; Reddi, AS, 1991)
"Addition of the cholinergic agents acetylcholine or carbamylcholine (CCh) to suspensions of human endometrial adenocarcinoma cells (Ishikawa line) preincubated with [3H] myoinositol promoted a rapid concentration-dependent hydrolysis of labeled phosphoinositides to inositol tris-, bis-, and monophosphates with EC50 values (mean +/- SE) of 3."3.67Regulation of phosphoinositide hydrolysis in transformed human endometrial cells. ( Gurpide, E; Weiss, DJ, 1988)
"The inositol compounds were administered via the drinking fluid."1.34Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds. ( Liao, J; Lu, GG; Seril, DN; Yang, AL; Yang, GY, 2007)
" Toxicity studies allowed us to establish the LD50 (750 mg/kg body weight)."1.30A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo. ( Cerutti, ML; Colombo, L; D'Orio, E; Davel, L; Diament, M; Eiján, AM; Gelpi, ME; Leicach, SR; Parma, P; Stillitani, I, 1999)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.76)18.7374
1990's5 (29.41)18.2507
2000's5 (29.41)29.6817
2010's5 (29.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
An, YJ1
Cho, HR1
Kim, TM1
Keam, B1
Kim, JW1
Wen, H1
Park, CK1
Lee, SH1
Im, SA1
Kim, JE1
Choi, SH1
Park, S1
Fu, M1
Song, Y1
Wen, Z1
Lu, X1
Cui, L1
Kassie, F3
Matise, I2
Negia, M1
Lahti, D1
Pan, Y1
Scherber, R1
Upadhyaya, P3
Hecht, SS3
Raina, K1
Serkova, NJ1
Agarwal, R1
Kalscheuer, S1
Ma, L1
Melkamu, T2
Endalew, A1
Luo, X1
Yakoub, D1
Keun, HC1
Goldin, R1
Hanna, GB1
Liao, J1
Seril, DN1
Yang, AL1
Lu, GG1
Yang, GY1
Fedier, A1
Erdmann, R1
Boulikas, T1
Fink, D1
Schiebler, ML1
Miyamoto, KK1
White, M1
Maygarden, SJ1
Mohler, JL1
Eiján, AM2
Puricelli, L1
Bal de Kier Joffé, E1
Elías, C1
Leicach, SR2
Cadenas, RA1
Cerutti, ML1
D'Orio, E1
Davel, L1
Colombo, L1
Parma, P1
Diament, M1
Stillitani, I1
Gelpi, ME1
Gunning, WT1
Kramer, PM1
Lubet, RA1
Steele, VE1
Pereira, MA1
Narayanan, U1
Hilf, R1
Reddi, AS1
Jyothirmayi, GN1
DeAngelis, B1
Kabaria, V1
Frank, O1
Baker, H1
Galons, JP1
Fantini, J1
Vion-Dury, J1
Cozzone, PJ1
Canioni, P1
Weiss, DJ1
Gurpide, E1

Other Studies

17 other studies available for inositol and Adenocarcinoma

ArticleYear
An NMR metabolomics approach for the diagnosis of leptomeningeal carcinomatosis in lung adenocarcinoma cancer patients.
    International journal of cancer, 2015, Jan-01, Volume: 136, Issue:1

    Topics: Adenocarcinoma; Alanine; Area Under Curve; Biomarkers, Tumor; Case-Control Studies; Citric Acid; Cre

2015
Inositol Hexaphosphate and Inositol Inhibit Colorectal Cancer Metastasis to the Liver in BALB/c Mice.
    Nutrients, 2016, May-12, Volume: 8, Issue:5

    Topics: Adenocarcinoma; Animals; Colorectal Neoplasms; Female; Inositol; Liver Neoplasms; Mice; Mice, Inbred

2016
Combinations of N-Acetyl-S-(N-2-Phenethylthiocarbamoyl)-L-Cysteine and myo-inositol inhibit tobacco carcinogen-induced lung adenocarcinoma in mice.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; bcl-Associated Death Protei

2008
Silibinin feeding alters the metabolic profile in TRAMP prostatic tumors: 1H-NMRS-based metabolomics study.
    Cancer research, 2009, May-01, Volume: 69, Issue:9

    Topics: Adenocarcinoma; Animals; Biomarkers, Tumor; Choline; Citrates; Glucose; Inositol; Lipid Metabolism;

2009
Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.
    Carcinogenesis, 2010, Volume: 31, Issue:2

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Prol

2010
Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.
    Carcinogenesis, 2010, Volume: 31, Issue:9

    Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Antineoplastic Combined Chemotherapy Protocols; Be

2010
Metabolic profiling detects field effects in nondysplastic tissue from esophageal cancer patients.
    Cancer research, 2010, Nov-15, Volume: 70, Issue:22

    Topics: Adenocarcinoma; Barrett Esophagus; Cell Transformation, Neoplastic; Diagnosis, Differential; Esophag

2010
Inhibition of chronic ulcerative colitis associated adenocarcinoma development in mice by inositol compounds.
    Carcinogenesis, 2007, Volume: 28, Issue:2

    Topics: Adenocarcinoma; Animals; Body Weight; Chronic Disease; Colitis, Ulcerative; Colorectal Neoplasms; Fe

2007
Potential of the Akt inhibitor LY294005 to antagonize the efficacy of Cisplatin against HCT116 tumor cells in a DNA mismatch repair-dependent manner.
    International journal of oncology, 2006, Volume: 29, Issue:5

    Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Antineoplastic Agents; Base Pair Mismatch; Car

2006
In vitro high resolution 1H-spectroscopy of the human prostate: benign prostatic hyperplasia, normal peripheral zone and adenocarcinoma.
    Magnetic resonance in medicine, 1993, Volume: 29, Issue:3

    Topics: Acetates; Adenocarcinoma; Citrates; Glutamates; Humans; Hydrogen; Inositol; Lactates; Magnetic Reson

1993
Action of nitrogenated and sulfonylated inositol derivatives upon the proliferation in vitro of normal mouse cells and tumor mouse cells.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 1994, Volume: 15, Issue:6

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Cycle; Cell Division; Cell Survival; Cells, Cul

1994
A synthetic, nitrogenated antimetastatic and anti-angiogenic compound with low toxicity in vivo.
    International journal of oncology, 1999, Volume: 14, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Division; Drug Screening Assays, Antitumor; Fem

1999
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice.
    Experimental lung research, 2000, Volume: 26, Issue:8

    Topics: Adenocarcinoma; Adenoma; Animals; Anticarcinogenic Agents; Carcinogens; Chemoprevention; Dexamethaso

2000
Effects of diabetes and insulin on phosphoinositide metabolism in R3230AC mammary tumors.
    Cancer biochemistry biophysics, 1992, Volume: 13, Issue:2

    Topics: Adenocarcinoma; Animals; Biological Transport, Active; Diabetes Mellitus, Experimental; Female; Inos

1992
Vitamin and micronutrient concentrations in cyclosporine-induced renal tumor from diabetic rats.
    Life sciences, 1991, Volume: 49, Issue:21

    Topics: Adenocarcinoma; Animals; Biopterins; Blood Glucose; Carnitine; Cyclosporine; Diabetes Mellitus, Expe

1991
Metabolic changes in undifferentiated and differentiated human colon adenocarcinoma cells studied by multinuclear magnetic resonance spectroscopy.
    Biochimie, 1989, Volume: 71, Issue:8

    Topics: Acetates; Adenocarcinoma; Carbon Isotopes; Cell Differentiation; Colonic Neoplasms; Energy Metabolis

1989
Regulation of phosphoinositide hydrolysis in transformed human endometrial cells.
    Endocrinology, 1988, Volume: 123, Issue:2

    Topics: Acetylcholine; Adenocarcinoma; Atropine; Carbachol; Cell Differentiation; Chlorides; Endometrium; Fe

1988