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inositol and Abnormalities, Drug-Induced

inositol has been researched along with Abnormalities, Drug-Induced in 5 studies

Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"Valproic acid (VPA) is an anticonvulsant drug that is widely used therapeutically for a variety of neurological conditions."1.33Myo-inositol enhances teratogenicity of valproic acid in the mouse. ( Finnell, RH; Giavini, E; Massa, V; Wlodarczyk, B, 2006)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Massa, V1
Wlodarczyk, B1
Giavini, E1
Finnell, RH1
Sconzo, G1
Cascino, D1
Amore, G1
Geraci, F1
Giudice, G1
Wentzel, P1
Wentzel, CR1
Gäreskog, MB1
Eriksson, UJ1
Busa, WB1
Gimlich, RL1
Linari, G1

Other Studies

5 other studies available for inositol and Abnormalities, Drug-Induced

ArticleYear
Myo-inositol enhances teratogenicity of valproic acid in the mouse.
    Birth defects research. Part A, Clinical and molecular teratology, 2006, Volume: 76, Issue:3

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Animals; Anticonvulsants; Drug Synergism; Embryo

2006
Effect of the IMPase inhibitor L690,330 on sea urchin development.
    Cell biology international, 1998, Volume: 22, Issue:2

    Topics: 5'-Nucleotidase; Abnormalities, Drug-Induced; Animals; Calcium-Calmodulin-Dependent Protein Kinases;

1998
Induction of embryonic dysmorphogenesis by high glucose concentration, disturbed inositol metabolism, and inhibited protein kinase C activity.
    Teratology, 2001, Volume: 63, Issue:5

    Topics: Abnormalities, Drug-Induced; Acetylcysteine; Animals; Diabetes Mellitus, Experimental; Dose-Response

2001
Lithium-induced teratogenesis in frog embryos prevented by a polyphosphoinositide cycle intermediate or a diacylglycerol analog.
    Developmental biology, 1989, Volume: 132, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Blastomeres; Central Nervous System; Diglycerides; Exocrine Gl

1989
Observations on the synthesis, chemical hydrolysis in vitro and toxicity of a new ester of nicotinic acid: the mesoinosito pentanicotinate.
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Blood; Body Weight; Chemistry, Pharmaceutica

1970