inositol has been researched along with Abnormalities, Congenital in 15 studies
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.
inositol : Any cyclohexane-1,2,3,4,5,6-hexol.
1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.
muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In recent years, interest has been focused to the study of the two major inositol stereoisomers: myo-inositol (MI) and d-chiro-inositol (DCI), because of their involvement, as second messengers of insulin, in several insulin-dependent processes, such as metabolic syndrome and polycystic ovary syndrome." | 7.81 | Results from the International Consensus Conference on Myo-inositol and d-chiro-inositol in Obstetrics and Gynecology: the link between metabolic syndrome and PCOS. ( Benvenga, S; Bevilacqua, A; Bizzarri, M; Carlomagno, G; Cavalli, P; Chiu, TT; D'Anna, R; Devroey, P; Di Renzo, GC; Facchinetti, F; Gerli, S; Hod, M; Kamenov, ZA; Lanzone, A; Oliva, MM; Soulage, C, 2015) |
| "We have shown that myo-inositol in the cultured rat embryo is diminished whenever malformations are induced by hyperglycemia and that the malformations and reductions of tissue myo-inositol content are not corrected by aldose reductase inhibitors." | 7.68 | Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia. ( Freinkel, N; Garcia-Palmer, FJ; Weigensberg, MJ, 1990) |
| "In recent years, interest has been focused to the study of the two major inositol stereoisomers: myo-inositol (MI) and d-chiro-inositol (DCI), because of their involvement, as second messengers of insulin, in several insulin-dependent processes, such as metabolic syndrome and polycystic ovary syndrome." | 3.81 | Results from the International Consensus Conference on Myo-inositol and d-chiro-inositol in Obstetrics and Gynecology: the link between metabolic syndrome and PCOS. ( Benvenga, S; Bevilacqua, A; Bizzarri, M; Carlomagno, G; Cavalli, P; Chiu, TT; D'Anna, R; Devroey, P; Di Renzo, GC; Facchinetti, F; Gerli, S; Hod, M; Kamenov, ZA; Lanzone, A; Oliva, MM; Soulage, C, 2015) |
| "We have shown that myo-inositol in the cultured rat embryo is diminished whenever malformations are induced by hyperglycemia and that the malformations and reductions of tissue myo-inositol content are not corrected by aldose reductase inhibitors." | 3.68 | Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia. ( Freinkel, N; Garcia-Palmer, FJ; Weigensberg, MJ, 1990) |
| "The incidence rate of birth defects was 3." | 1.56 | The Effects of Inositol Metabolism in Pregnant Women on Offspring in the North and South of China. ( Cui, M; Guan, Z; Guo, J; Li, S; Niu, B; Qin, J; Wang, J; Wang, X; Yue, H; Zhu, Z, 2020) |
| " Dose-response studies disclosed that incremental increases in [3H]InsP1 (129-420%) are observed over a concentration range of 10-1,000 nM." | 1.29 | Glucose and scyllo-inositol impair phosphoinositide hydrolysis in the 10.5-day cultured rat conceptus: a role in dysmorphogenesis? ( Metzger, BE; Strieleman, PJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.67) | 18.7374 |
| 1990's | 9 (60.00) | 18.2507 |
| 2000's | 2 (13.33) | 29.6817 |
| 2010's | 2 (13.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, X | 1 |
| Yue, H | 1 |
| Li, S | 1 |
| Guo, J | 1 |
| Guan, Z | 1 |
| Qin, J | 1 |
| Zhu, Z | 1 |
| Niu, B | 1 |
| Cui, M | 1 |
| Wang, J | 1 |
| Dong, D | 1 |
| Reece, EA | 3 |
| Lin, X | 1 |
| Wu, Y | 1 |
| AriasVillela, N | 1 |
| Yang, P | 1 |
| Facchinetti, F | 1 |
| Bizzarri, M | 1 |
| Benvenga, S | 1 |
| D'Anna, R | 1 |
| Lanzone, A | 1 |
| Soulage, C | 1 |
| Di Renzo, GC | 1 |
| Hod, M | 5 |
| Cavalli, P | 1 |
| Chiu, TT | 1 |
| Kamenov, ZA | 1 |
| Bevilacqua, A | 1 |
| Carlomagno, G | 1 |
| Gerli, S | 1 |
| Oliva, MM | 1 |
| Devroey, P | 1 |
| Wentzel, P | 2 |
| Eriksson, UJ | 2 |
| Cederberg, J | 1 |
| Goto, MP | 1 |
| Goldman, AS | 1 |
| Strieleman, PJ | 1 |
| Metzger, BE | 1 |
| Wu, YK | 1 |
| Star, S | 3 |
| Passonneau, JV | 2 |
| Unterman, TG | 3 |
| Freinkel, N | 4 |
| Shafrir, E | 1 |
| Passonneau, J | 1 |
| Weigensberg, MJ | 1 |
| Garcia-Palmer, FJ | 1 |
6 reviews available for inositol and Abnormalities, Congenital
| Article | Year |
|---|---|
New development of the yolk sac theory in diabetic embryopathy: molecular mechanism and link to structural birth defects.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Female; Glucose; Humans; Hypoxia-Inducible Fact | 2016 |
Can we prevent diabetic birth defects with micronutrients?
Topics: Animals; Antioxidants; Arachidonic Acid; Congenital Abnormalities; Dietary Supplements; Female; Feta | 2009 |
Congenital malformations in offspring of diabetic mothers--animal and human studies.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Diabetes Complications; Female; Gene Expression | 2003 |
Diabetic embryopathy.
Topics: Animals; Congenital Abnormalities; Female; Fetal Diseases; Humans; Inositol; Pregnancy; Pregnancy in | 1994 |
The pathogenesis of diabetes-associated congenital malformations.
Topics: Animals; Antioxidants; Arachidonic Acids; Congenital Abnormalities; Embryonic and Fetal Development; | 1996 |
Advances in the understanding of diabetic embryopathy: signal transduction.
Topics: Animals; Arachidonic Acid; Congenital Abnormalities; Diabetes Mellitus, Experimental; Embryo, Mammal | 1996 |
9 other studies available for inositol and Abnormalities, Congenital
| Article | Year |
|---|---|
The Effects of Inositol Metabolism in Pregnant Women on Offspring in the North and South of China.
Topics: Adult; China; Congenital Abnormalities; Female; Fetal Development; Geography; Humans; Incidence; Inf | 2020 |
Results from the International Consensus Conference on Myo-inositol and d-chiro-inositol in Obstetrics and Gynecology: the link between metabolic syndrome and PCOS.
Topics: Congenital Abnormalities; Diabetes, Gestational; Female; Humans; Inositol; Insulin Resistance; Metab | 2015 |
Glucose and scyllo-inositol impair phosphoinositide hydrolysis in the 10.5-day cultured rat conceptus: a role in dysmorphogenesis?
Topics: Animals; Congenital Abnormalities; Embryo, Mammalian; Embryonic and Fetal Development; Female; Gesta | 1993 |
Prevention of diabetic embryopathy in offspring of diabetic rats with use of a cocktail of deficient substrates and an antioxidant.
Topics: Animals; Antioxidants; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experimental; Dru | 1997 |
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: prevention of dysmorphogenesis with aldose reductase inhibitors and myo-inositol.
Topics: Aldehyde Reductase; Animals; Blood; Congenital Abnormalities; Culture Media; Culture Techniques; Fem | 1991 |
Polyol pathway and fetal malformations: a search for the right mode of prevention.
Topics: Aldehyde Reductase; Animals; Congenital Abnormalities; Female; Fetal Diseases; Glucose; Inositol; Pr | 1990 |
Glucose-induced dysmorphogenesis in the cultured rat conceptus: prevention by supplementation with myo-inositol.
Topics: Animals; Congenital Abnormalities; Culture Media; Culture Techniques; Disease Models, Animal; Embryo | 1990 |
Uptake of myo-inositol by early-somite rat conceptus. Transport kinetics and effects of hyperglycemia.
Topics: Animals; Biological Transport; Congenital Abnormalities; Culture Techniques; DNA; Embryo, Mammalian; | 1990 |
Effect of hyperglycemia on sorbitol and myo-inositol content of cultured rat conceptus: failure of aldose reductase inhibitors to modify myo-inositol depletion and dysmorphogenesis.
Topics: Aldehyde Reductase; Animals; Blood Glucose; Congenital Abnormalities; Culture Techniques; Female; Fe | 1986 |