inosine-diphosphate has been researched along with Coma* in 2 studies
2 other study(ies) available for inosine-diphosphate and Coma
| Article | Year |
|---|---|
[Use of cytoflavin into the complex intensive therapy of acute cerebral insufficiency caused by poisoning].
In the result of treatment of 147 patients with toxic acute brain insufficiency were revealed that the employment of citoflavin (20 ml with 400 ml 5% glucosae twice a day) in 7 days intensive therapy of acute brain insufficiency leaded to decrease of hypoxic brain damages and intensity of brain depression, what was revealed in improvement of brain bioelectric activity. Rehabilitation of central nervous system regulation function and life-support systems leaded to quick rehabilitation of respiratory part of oxygen transport. These changes in acute period leaded to quick reparation of cognitive-mnestic functions and social adaptation. The employment of citoflavin leaded to improvement of clinic of toxicohypoxic encephalopathy and to decrease of secondary lung complications (decrease of coma-period from 45,3 ± 8,2 to 27,7 ± 6,9 hours; decrease of secondary lung complications from 72,7% to 35,9%). Topics: Central Nervous System; Coma; Drug Combinations; Electroencephalography; Female; Flavin Mononucleotide; Glucose; Humans; Hypoxia, Brain; Inosine Diphosphate; Male; Neuroprotective Agents; Neurotoxicity Syndromes; Neurotoxins; Niacinamide; Succinates | 2012 |
[The use of cytoflavin in combined neurometabolic therapy of acute cerebral insufficiency associated with acute poisoning with neurotropic poisons].
Examination and treatment of 262 patients with severe acute intoxication by neurotropic poisons and unaffected oxygen delivery system showed that inclusion of cytoflavin in combined neurometabolic therapy of acute cerebral insufficiency significantly reduced severity of metabolic disorders. Specifically, tissue hypoxy, endotoxicosis, lipid peroxidation activity, and immunosuppression decreased while antioxidative protection and clinical picture were improved. Duration of comatose state and artificial lung ventilation was reduced from 64.5 +/- 15.1 to 28.8 +/- 10.2 hours and that of critical condition from 117.2 +/- 17.2 to 63.7 +/- 9.2 hours. Overall lethality dropped from 16 to 9.9%. Topics: Acute Disease; CD3 Complex; CD4 Antigens; CD8 Antigens; Coma; Critical Illness; Drug Combinations; Flavin Mononucleotide; Humans; Hypoxia, Brain; Inosine Diphosphate; Lymphocytes; Neuroprotective Agents; Neurotoxicity Syndromes; Niacinamide; Poisoning; Receptors, Interleukin-2; Respiration, Artificial; Succinates | 2010 |