inosine-diphosphate and Atrial-Fibrillation

The aim of the study was to examine effect of cardioversion (CV) on the subjective and objective status of patients with persistent atrial fibrillation (AF) receiving different therapy. The study included 4 groups of patients (n = 85). Group 1 (n = 30) were given standard treatment. In group 2 (n = 25), standard therapy was supplemented by i.v. injections of emoxipin (200 mg/day). Treatment of group 3 (n = 10) included mildronat (50 mg/day, i.v.), patients of group 4 (n = 20) were given riboxin (200 mg/day, i.v.). It was shown that the recovery of sinus rhythm improved the quality of life and parameters of cardiovascular function in all the treated patients.

Topics: Atrial Fibrillation; Cardiovascular Agents; Echocardiography, Doppler; Electric Countershock; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Heart Rate; Humans; Injections, Intravenous; Inosine Diphosphate; Male; Methylhydrazines; Middle Aged; Quality of Life; Stroke Volume; Treatment Outcome