inosine-dialdehyde and Anemia

inosine-dialdehyde has been researched along with Anemia* in 1 studies

*Anemia: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN. [MeSH]

Trials

1 trial(s) available for inosine-dialdehyde and Anemia

Article	Year
Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: the INsufficient Oxygenation in the Intensive Care U BMJ open, 2020, 05-17, Volume: 10, Issue:5 The recently developed protoporphyrin IX-triple state lifetime technique measures mitochondrial oxygenation tension (mitoPO. We perform a prospective multicentre observational study in three mixed intensive care units in the Netherlands with critically ill patients with anaemia in whom an RBC transfusion is planned. The skin of the anterior chest wall of the patients is primed with a 5-aminolevulinic acid patch for 4 hours for induction of mitochondrial protoporphyrin-IX to enable measurements of mitoPO. The institutional ethics committee of each participating centre approved the study (reference P16.303), which will be conducted according to the 1964 Helsinki declaration and its later amendments. The results will be submitted for publication in peer-reviewed journals and presented at scientific conferences.. NCT03092297. Topics: Anemia; Cohort Studies; Critical Illness; Erythrocyte Transfusion; Humans; Inosine; Intensive Care Units; Male; Netherlands; Oxygen; Prospective Studies	2020

Article

Year

Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: the INsufficient Oxygenation in the Intensive Care U

BMJ open, 2020, 05-17, Volume: 10, Issue:5

The recently developed protoporphyrin IX-triple state lifetime technique measures mitochondrial oxygenation tension (mitoPO. We perform a prospective multicentre observational study in three mixed intensive care units in the Netherlands with critically ill patients with anaemia in whom an RBC transfusion is planned. The skin of the anterior chest wall of the patients is primed with a 5-aminolevulinic acid patch for 4 hours for induction of mitochondrial protoporphyrin-IX to enable measurements of mitoPO. The institutional ethics committee of each participating centre approved the study (reference P16.303), which will be conducted according to the 1964 Helsinki declaration and its later amendments. The results will be submitted for publication in peer-reviewed journals and presented at scientific conferences.. NCT03092297.

Topics: Anemia; Cohort Studies; Critical Illness; Erythrocyte Transfusion; Humans; Inosine; Intensive Care Units; Male; Netherlands; Oxygen; Prospective Studies

2020