indoprofen has been researched along with Neoplasms in 3 studies
Indoprofen: A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)
indoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indoprofen and morphine were not significantly different as regards pain relief, but both were significantly more effective than placebo." | 6.65 | Effect of i.v. indoprofen on cancer pain and serum prolactin and growth hormone levels--a controlled pharmacologic study vs i. m. morphine and placebo. ( Bruni, G; Defraia, E; Massidda, B; Parrinello, L; Pellegrini, A; Pellegrini, P; Rigamonti, G; Sacchetti, G; Usai, A, 1983) |
| " The double-blind cross-over trial was carried out in 18 patients of both sexes suffering from pain due to malignant tumours who received single doses of 200 mg indoprofen and 250 mg naproxen p." | 5.04 | A controlled study of the analgetic effect of two non-steroidal anti-inflammatory drugs in cancer pain. ( Emanueli, A; Mandelli, V; Martino, G; Ventafridda, V, 1978) |
| "Indoprofen and morphine were not significantly different as regards pain relief, but both were significantly more effective than placebo." | 2.65 | Effect of i.v. indoprofen on cancer pain and serum prolactin and growth hormone levels--a controlled pharmacologic study vs i. m. morphine and placebo. ( Bruni, G; Defraia, E; Massidda, B; Parrinello, L; Pellegrini, A; Pellegrini, P; Rigamonti, G; Sacchetti, G; Usai, A, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lin, R | 1 |
| Elf, S | 1 |
| Shan, C | 1 |
| Kang, HB | 1 |
| Ji, Q | 1 |
| Zhou, L | 1 |
| Hitosugi, T | 1 |
| Zhang, L | 1 |
| Zhang, S | 1 |
| Seo, JH | 1 |
| Xie, J | 1 |
| Tucker, M | 1 |
| Gu, TL | 1 |
| Sudderth, J | 1 |
| Jiang, L | 1 |
| Mitsche, M | 1 |
| DeBerardinis, RJ | 1 |
| Wu, S | 1 |
| Li, Y | 1 |
| Mao, H | 1 |
| Chen, PR | 1 |
| Wang, D | 1 |
| Chen, GZ | 1 |
| Hurwitz, SJ | 1 |
| Lonial, S | 1 |
| Arellano, ML | 1 |
| Khoury, HJ | 1 |
| Khuri, FR | 1 |
| Lee, BH | 1 |
| Lei, Q | 1 |
| Brat, DJ | 1 |
| Ye, K | 1 |
| Boggon, TJ | 1 |
| He, C | 1 |
| Kang, S | 1 |
| Fan, J | 1 |
| Chen, J | 1 |
| Pellegrini, A | 1 |
| Massidda, B | 1 |
| Pellegrini, P | 1 |
| Defraia, E | 1 |
| Usai, A | 1 |
| Parrinello, L | 1 |
| Bruni, G | 1 |
| Rigamonti, G | 1 |
| Sacchetti, G | 1 |
| Martino, G | 1 |
| Emanueli, A | 1 |
| Mandelli, V | 1 |
| Ventafridda, V | 1 |
1 review available for indoprofen and Neoplasms
| Article | Year |
|---|---|
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms; | 2015 |
2 trials available for indoprofen and Neoplasms
| Article | Year |
|---|---|
Effect of i.v. indoprofen on cancer pain and serum prolactin and growth hormone levels--a controlled pharmacologic study vs i. m. morphine and placebo.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Growth Hormone; Humans; Indoprof | 1983 |
A controlled study of the analgetic effect of two non-steroidal anti-inflammatory drugs in cancer pain.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indoprofen; Male; Middle | 1978 |