indoprofen has been researched along with Germinoblastoma in 1 studies
Indoprofen: A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)
indoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "(R)-Ketoprofen (1) was previously reported to be a potent and specific noncompetitive inhibitor of CXCL8-induced human PMNs chemotaxis." | 1.33 | 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. ( Allegretti, M; Berdini, V; Bertini, R; Bizzarri, C; Cesta, MC; Colotta, F; Di Bello, N; Di Bitondo, R; Di Cioccio, V; Fantucci, P; Florio, S; Galliera, E; Locati, M; Nano, G; Nicolini, L; Russo, V; Topai, A; Zampella, G, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allegretti, M | 1 |
| Bertini, R | 1 |
| Cesta, MC | 1 |
| Bizzarri, C | 1 |
| Di Bitondo, R | 1 |
| Di Cioccio, V | 1 |
| Galliera, E | 1 |
| Berdini, V | 1 |
| Topai, A | 1 |
| Zampella, G | 1 |
| Russo, V | 1 |
| Di Bello, N | 1 |
| Nano, G | 1 |
| Nicolini, L | 1 |
| Locati, M | 1 |
| Fantucci, P | 1 |
| Florio, S | 1 |
| Colotta, F | 1 |
1 other study available for indoprofen and Germinoblastoma
| Article | Year |
|---|---|
2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors.
Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Movement; Chemokines, CXC; Chemotaxis, Leukocyte; Fem | 2005 |