indoprofen has been researched along with Drug Hypersensitivity in 2 studies
Indoprofen: A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)
indoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this paper we report on the positive identification of an indoprofen-induced severe pancytopenia in a multi-drug-treated patient with active systemic lupus erythematosus by use of a drug-specific lymphocyte transformation test." | 3.67 | Indoprofen-induced aplastic anemia in active connective tissue disease detected by drug-specific lymphocyte transformation. ( Berg, PA; Daniel, PT; Saal, JG, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Varga, JM | 1 |
| Kalchschmid, G | 1 |
| Klein, GF | 1 |
| Fritsch, P | 1 |
| Saal, JG | 1 |
| Daniel, PT | 1 |
| Berg, PA | 1 |
2 other studies available for indoprofen and Drug Hypersensitivity
| Article | Year |
|---|---|
Mechanism of allergic cross-reactions--I. Multispecific binding of ligands to a mouse monoclonal anti-DNP IgE antibody.
Topics: Amino Acids; Antibodies, Monoclonal; Antibody Specificity; Cinnamates; Cross Reactions; Dinitropheno | 1991 |
Indoprofen-induced aplastic anemia in active connective tissue disease detected by drug-specific lymphocyte transformation.
Topics: Adult; Agranulocytosis; Anemia, Aplastic; Diagnosis, Differential; Drug Hypersensitivity; Drug Thera | 1986 |