indoprofen has been researched along with Complication, Postoperative in 3 studies
Indoprofen: A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)
indoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A double-blind, controlled trial is described in which a total of forty hospital in-patients suffering from severe post-operative pain were randomly allocated to treatment with one of two non-steroidal anti-inflammatory drugs, namely, either indoprofen which has a short half-life (two-hours) or naproxen which has a long half-life (thirteen hours)." | 5.04 | Kinetics of analgesic response in man; an example with two non-steroidal anti-inflammatory analgesic drugs. ( Ferrati, GC; Parrinello, L; Sacchetti, G; Salami, A, 1978) |
| " A double-placebo method was used, as dosage regimens for the two treatments were different." | 2.66 | The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery. ( Olstad, OA; Skjelbred, P, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sacchetti, G | 1 |
| Ferrati, GC | 1 |
| Parrinello, L | 1 |
| Salami, A | 1 |
| Raucci, D | 1 |
| Caso, P | 1 |
| Gualtieri, S | 1 |
| Iarussi, D | 1 |
| Jacono, A | 1 |
| Olstad, OA | 1 |
| Skjelbred, P | 1 |
2 trials available for indoprofen and Complication, Postoperative
| Article | Year |
|---|---|
Kinetics of analgesic response in man; an example with two non-steroidal anti-inflammatory analgesic drugs.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indoprofen; Kineti | 1978 |
The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Female; Hemorrhage; Humans; Indoprofen; | 1986 |
1 other study available for indoprofen and Complication, Postoperative
| Article | Year |
|---|---|
[Anti-aggregant therapy in subjects with a cardiac valve prosthesis and under treatment with oral anticoagulants].
Topics: Adult; Anticoagulants; Blood Coagulation; Female; Heart Valve Diseases; Heart Valve Prosthesis; Huma | 1979 |