indoprofen has been researched along with Adult Spinal Muscular Atrophy in 1 studies
Indoprofen: A drug that has analgesic and anti-inflammatory properties. Following reports of adverse reactions including reports of carcinogenicity in animal studies it was withdrawn from the market worldwide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p21)
indoprofen : A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xiao, J | 1 |
| Marugan, JJ | 1 |
| Zheng, W | 1 |
| Titus, S | 1 |
| Southall, N | 1 |
| Cherry, JJ | 1 |
| Evans, M | 1 |
| Androphy, EJ | 1 |
| Austin, CP | 1 |
1 other study available for indoprofen and Adult Spinal Muscular Atrophy
| Article | Year |
|---|---|
Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
Topics: Alternative Splicing; Caco-2 Cells; Cell Membrane Permeability; Drug Design; Exons; Fibroblasts; Gen | 2011 |