Page last updated: 2024-10-29

indomethacin and Water Intoxication

indomethacin has been researched along with Water Intoxication in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Water Intoxication: A condition resulting from the excessive retention of water with sodium depletion.

Research Excerpts

ExcerptRelevanceReference
" We report a case of congenital nephrogenic diabetes insipidus that was complicated by paradoxical water intoxication secondary to liberal water intake and the initiation of hydrochlorothiazide and indomethacin combination therapy."3.75Nephrogenic diabetes insipidus: treat with caution. ( Boussemart, T; Champion, G; Martin-Coignard, D; Nsota, J, 2009)
"We report the case of a patient with multiple myeloma who developed acute life-threatening water intoxication following treatment with oral indomethacin and low dose intravenous cyclophosphamide."3.67Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin. ( Murray, JA; Webberley, MJ, 1989)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boussemart, T1
Nsota, J1
Martin-Coignard, D1
Champion, G1
Agnoli, GC1
Borgatti, R1
Cacciari, M1
Ikonomu, E1
Lenzi, P1
Marinelli, M1
Bhargava, R1
Lewandowski, BJ1
Webberley, MJ1
Murray, JA1
Petersson, I1
Nilsson, G1
Hansson, BG1
Hedner, T1

Trials

1 trial available for indomethacin and Water Intoxication

ArticleYear
Urinary prostanoid excretion in healthy women with different degrees of induced potassium depletion.
    Prostaglandins, leukotrienes, and essential fatty acids, 1992, Volume: 46, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Chlorides; Dinoprostone; Female; Glomerular Filtration Rate; Hu

1992

Other Studies

4 other studies available for indomethacin and Water Intoxication

ArticleYear
Nephrogenic diabetes insipidus: treat with caution.
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:9

    Topics: Amiloride; Combined Modality Therapy; Cyclooxygenase Inhibitors; Diabetes Insipidus, Nephrogenic; Di

2009
Water intoxication: a complication of pelvic US in a patient with syndrome of inappropriate antidiuretic hormone secretion.
    Radiology, 1991, Volume: 180, Issue:3

    Topics: Aged; Female; Humans; Inappropriate ADH Syndrome; Indomethacin; Pelvis; Ultrasonography; Water Intox

1991
Life-threatening acute hyponatraemia induced by low dose cyclophosphamide and indomethacin.
    Postgraduate medical journal, 1989, Volume: 65, Issue:770

    Topics: Aged; Cyclophosphamide; Drug Interactions; Humans; Hyponatremia; Indomethacin; Male; Multiple Myelom

1989
Water intoxication associated with non-steroidal anti-inflammatory drug therapy.
    Acta medica Scandinavica, 1987, Volume: 221, Issue:2

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; Female; Humans; Hy

1987