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indomethacin and Vertigo

indomethacin has been researched along with Vertigo in 16 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)

Research Excerpts

ExcerptRelevanceReference
"Lumiracoxib is as effective as indomethacin for treatment of acute gout and may have a better safety and tolerability profile."9.12Lumiracoxib 400 mg once daily is comparable to indomethacin 50 mg three times daily for the treatment of acute flares of gout. ( Derbot, J; Jung, T; Krammer, G; Kreiss, A; Litschig, S; Mysler, E; Tate, GA; Thurston, H; Willburger, RE, 2007)
"The efficacy and tolerability of aceclofenac (100 mg bid; n = 109), a new non-steroidal anti-inflammatory agent, was compared to that of indomethacin (50 mg bid; n = 110) in a multi-centre, 12-week, randomized, double-blind clinical trial in patients with rheumatoid arthritis."9.08The efficacy and tolerability of aceclofenac compared to indomethacin in patients with rheumatoid arthritis. ( Bowdler, J; Kornasoff, D; Maisenbacher, J; Raber, A, 1996)
"In a multicenter double-blind cross-over trial the therapeutic effect and the tolerance of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen) and indometacin were compared including 46 patients with rheumatoid arthritis, 35 patients with ankylosing spondylitis and 19 patients with osteoarthrosis."9.04[Clinical results of a multicentral double-blind examination of naproxen compared to indomethacin in chronic rheumatoid arthritis, ankylosing spondylitis, and osteoarthrosis]. ( Aeidler, H, 1975)
"Lumiracoxib is as effective as indomethacin for treatment of acute gout and may have a better safety and tolerability profile."5.12Lumiracoxib 400 mg once daily is comparable to indomethacin 50 mg three times daily for the treatment of acute flares of gout. ( Derbot, J; Jung, T; Krammer, G; Kreiss, A; Litschig, S; Mysler, E; Tate, GA; Thurston, H; Willburger, RE, 2007)
"The efficacy and tolerability of aceclofenac (100 mg bid; n = 109), a new non-steroidal anti-inflammatory agent, was compared to that of indomethacin (50 mg bid; n = 110) in a multi-centre, 12-week, randomized, double-blind clinical trial in patients with rheumatoid arthritis."5.08The efficacy and tolerability of aceclofenac compared to indomethacin in patients with rheumatoid arthritis. ( Bowdler, J; Kornasoff, D; Maisenbacher, J; Raber, A, 1996)
"In a controlled trial the effect of indomethacin was studied in 54 patients with primary dysmenorrhea."5.04[Symptomatic therapy of primary dysmonorrhea by inhibition of prostaglandin synthesis with indomethacin (author's transl)]. ( Beutnagel, H; Cornely, M; Schönhöfer, PS, 1978)
"300 mg/day phenylbutazone, 210 mg/day indomethacin, and 600 mg/day pyrasanone were administered for 14 days to three randomised groups of patients respectively, consisting of a total of 76 subjects with various forms of non-infectious inflammation (osteoarthritis, fibrositis, rheumatoid arthritis, gout, phlebitis), in a double-blind trila designed to determine the activity of the three drugs and their tolerance."5.04[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa]. ( Bianchi, PA; Polli, EE; Vigo, PL, 1976)
"In a multicenter double-blind cross-over trial the therapeutic effect and the tolerance of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen) and indometacin were compared including 46 patients with rheumatoid arthritis, 35 patients with ankylosing spondylitis and 19 patients with osteoarthrosis."5.04[Clinical results of a multicentral double-blind examination of naproxen compared to indomethacin in chronic rheumatoid arthritis, ankylosing spondylitis, and osteoarthrosis]. ( Aeidler, H, 1975)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199014 (87.50)18.7374
1990's1 (6.25)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BUCHMANN, E2
Willburger, RE1
Mysler, E1
Derbot, J1
Jung, T1
Thurston, H1
Kreiss, A1
Litschig, S1
Krammer, G1
Tate, GA1
Kornasoff, D1
Maisenbacher, J1
Bowdler, J1
Raber, A1
Cornely, M1
Beutnagel, H1
Schönhöfer, PS1
Tausch, G1
Eberl, R1
Tuschl, P1
Bianchi, PA1
Vigo, PL1
Polli, EE1
Aeidler, H1
Kinsella, TD1
MacKenzie, KR1
Kim, SO1
Johnson, LG1
Caruso, I1
Watson, PG1
Lobascher, D1
Crifò, S1
Orestano, O1
Sidoli, A1
D'Arco, F1
Hahn, KJ1
Sturrock, RD1
Hart, FD1
Bain, LS1
Masheter, HC1
Svec, V1
Trnavský, K1
Zbojanová, M1

Trials

12 trials available for indomethacin and Vertigo

ArticleYear
Lumiracoxib 400 mg once daily is comparable to indomethacin 50 mg three times daily for the treatment of acute flares of gout.
    Rheumatology (Oxford, England), 2007, Volume: 46, Issue:7

    Topics: Abdominal Pain; Acute Disease; Administration, Oral; Adult; Aged; Analysis of Variance; Argentina; D

2007
The efficacy and tolerability of aceclofenac compared to indomethacin in patients with rheumatoid arthritis.
    Rheumatology international, 1996, Volume: 15, Issue:6

    Topics: Alanine Transaminase; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Diclofenac; El

1996
[Symptomatic therapy of primary dysmonorrhea by inhibition of prostaglandin synthesis with indomethacin (author's transl)].
    Geburtshilfe und Frauenheilkunde, 1978, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Double-Blind Method; Dysmenorrhea; Female; Humans; Indomethacin; Nausea; Placebos

1978
[Clinical experiences and results of clinical experimental studies with Voltaren in rheumatic diseases].
    Wiener medizinische Wochenschrift (1946), 1976, Mar-05, Volume: 126, Issue:10

    Topics: Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Diclofenac; DNA Repair; Drug Evalu

1976
[Evaluation of the effects of some non-steroid anti-inflammatory agents on the gastric mucosa].
    Minerva medica, 1976, Jul-07, Volume: 67, Issue:33

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Diarrhea; Drug Tolerance; Female; Fibromyalgia; Gas

1976
[Clinical results of a multicentral double-blind examination of naproxen compared to indomethacin in chronic rheumatoid arthritis, ankylosing spondylitis, and osteoarthrosis].
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2A

    Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Fema

1975
Evaluation of indomethacin by a controlled, cross-over technique in 30 patients with ankylosing spondylitis.
    Canadian Medical Association journal, 1967, Jun-03, Volume: 96, Issue:22

    Topics: Alkaline Phosphatase; Anemia, Hypochromic; Aspartate Aminotransferases; Aspirin; Central Nervous Sys

1967
The diagnosis and management of episcleritis and scleritis.
    Transactions of the ophthalmological societies of the United Kingdom, 1965, Volume: 85

    Topics: Arteritis; Arthritis, Rheumatoid; Behcet Syndrome; Clinical Trials as Topic; Deafness; Eczema; Epine

1965
A comparison of phenylbutazone and indometacin in the treatment of rheumatoid arthritis.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:6

    Topics: Analysis of Variance; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Evaluation Studies

1973
Double-blind cross-over comparison of indomethacin, flurbiprofen, and placebo in ankylosing spondylitis.
    Annals of the rheumatic diseases, 1974, Volume: 33, Issue:2

    Topics: Acetaminophen; Adult; Anti-Inflammatory Agents; Biphenyl Compounds; Blood Sedimentation; Clinical Tr

1974
Flufenamic acid and indomethacin in rheumatoid arthritis.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Diarrhea; Digestion; Fema

1966
Mefenamic acid compared with indomethacin and placebo in osteoarthritis.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Anti-Inflammatory Agents; Clinical Trials as Topic; Diarrhea; Digestion; Duodenal Ulcer; Female; Fol

1966

Other Studies

4 other studies available for indomethacin and Vertigo

ArticleYear
THE ANTIRHEUMATIC EFFECT OF INDOMETHACIN.
    Acta rheumatologica Scandinavica, 1965, Volume: 11

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antirheumatic Agents; Arthritis; Arthritis, Rheu

1965
[Undesired collateral effects of antirheumatic drugs: indomethacin].
    La Clinica terapeutica, 1972, Feb-29, Volume: 60, Issue:4

    Topics: Arthritis, Rheumatoid; Drug Eruptions; Gastrointestinal Diseases; Headache; Humans; Indomethacin; Pa

1972
[Preliminary studies of the possible audio-toxicity of indomethacin].
    Bollettino della Societa italiana di biologia sperimentale, 1974, Feb-15, Volume: 50, Issue:3

    Topics: Animals; Audiometry; Ear; Guinea Pigs; Hearing; Indomethacin; Labyrinth Diseases; Tinnitus; Vertigo;

1974
[Therapy of ankylosing spondylitis using indomethacin].
    Fysiatricky a reumatologicky vestnik, 1970, Volume: 48, Issue:4

    Topics: Adult; Dyspepsia; Female; Humans; Indomethacin; Male; Middle Aged; Spondylitis, Ankylosing; Vertigo

1970