indomethacin has been researched along with Vascular Diseases in 17 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Vascular Diseases: Pathological processes involving any of the BLOOD VESSELS in the cardiac or peripheral circulation. They include diseases of ARTERIES; VEINS; and rest of the vasculature system in the body.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thiamine deficiency is a condition that is known to cause damage to the nervous and cardiovascular systems because it interferes with cellular metabolism." | 1.40 | Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats. ( Capettini, LS; Cruz, JS; Gioda, CR; Lemos, VS, 2014) |
| "Whereas the articular complications of heterotopic ossification have been well documented, the vascular complications are less well known." | 1.29 | [Heterotopic ossification and vascular compression]. ( Brissot, R; Gallien, P; Le Bot, MP; Nicolas, B; Rivier, I; Robineau, S; Sarkis, S, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 2 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Steireif, C | 1 |
| García-Prieto, CF | 1 |
| Ruiz-Hurtado, G | 1 |
| Pulido-Olmo, H | 1 |
| Aranguez, I | 1 |
| Gil-Ortega, M | 1 |
| Somoza, B | 1 |
| Schönfelder, G | 1 |
| Schulz, A | 1 |
| Fernández-Alfonso, MS | 1 |
| Kreutz, R | 1 |
| Gioda, CR | 1 |
| Capettini, LS | 1 |
| Cruz, JS | 1 |
| Lemos, VS | 1 |
| Wong, RK | 1 |
| Pettit, AI | 1 |
| Quinn, PA | 1 |
| Jennings, SC | 1 |
| Davies, JE | 1 |
| Ng, LL | 1 |
| Taddei, S | 1 |
| Caraccio, N | 1 |
| Virdis, A | 1 |
| Dardano, A | 1 |
| Versari, D | 1 |
| Ghiadoni, L | 1 |
| Ferrannini, E | 1 |
| Salvetti, A | 1 |
| Monzani, F | 1 |
| de Boer, AC | 1 |
| Genton, E | 1 |
| Turpie, AG | 1 |
| Gallien, P | 1 |
| Nicolas, B | 1 |
| Le Bot, MP | 1 |
| Robineau, S | 1 |
| Rivier, I | 1 |
| Sarkis, S | 1 |
| Brissot, R | 1 |
| Hicks, RC | 1 |
| Moss, J | 1 |
| Higman, DJ | 1 |
| Greenhalgh, RM | 1 |
| Powell, JT | 1 |
| Alm, R | 1 |
| Edvinsson, L | 1 |
| Malmsjö, M | 1 |
| Levin, DL | 1 |
| Mills, LJ | 1 |
| Weinberg, AG | 1 |
| Franceschetti, AT | 1 |
| Shijo, H | 1 |
| Sasaki, H | 1 |
| Miyajima, Y | 1 |
| Okumura, M | 1 |
| Lundberg, C | 1 |
| Gardinali, M | 1 |
| Hugli, TE | 1 |
| Mikhailidis, DP | 1 |
| Barradas, MA | 1 |
| Maris, A | 1 |
| Jeremy, JY | 1 |
| Dandona, P | 1 |
| Bounameaux, H | 1 |
| Gresele, P | 1 |
| Hanss, M | 1 |
| De Cock, F | 1 |
| Vermylen, J | 1 |
| Collen, D | 1 |
| Calabro, JJ | 1 |
| Katz, RM | 1 |
| Maltz, BA | 1 |
| Vojtìsek, O | 1 |
| Kankovà, D | 1 |
| Temime, P | 1 |
3 reviews available for indomethacin and Vascular Diseases
| Article | Year |
|---|---|
Chemistry, measurement, and clinical significance of platelet specific proteins.
Topics: Aspirin; Beta-Globulins; beta-Thromboglobulin; Blood Coagulation; Blood Coagulation Factors; Blood P | 1982 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
[Polymyalgia rheumatica (comprehensive review)].
Topics: Age Factors; Aspirin; Blood Protein Electrophoresis; Blood Sedimentation; Diagnosis, Differential; G | 1973 |
2 trials available for indomethacin and Vascular Diseases
| Article | Year |
|---|---|
Low-grade systemic inflammation causes endothelial dysfunction in patients with Hashimoto's thyroiditis.
Topics: Acetylcholine; Adult; Algorithms; Ascorbic Acid; Celecoxib; Cyclooxygenase 2; Endothelium, Vascular; | 2006 |
Aspirin, indomethacin and dazoxiben do not affect the fibrinolytic activation induced by venous occlusion.
Topics: Aspirin; Double-Blind Method; Fibrinolysis; Humans; Imidazoles; Indomethacin; Male; Prostaglandins; | 1985 |
12 other studies available for indomethacin and Vascular Diseases
| Article | Year |
|---|---|
Dissecting the genetic predisposition to albuminuria and endothelial dysfunction in a genetic rat model.
Topics: Acetylcholine; Albuminuria; Animals; Aorta; Arginine; Endothelium, Vascular; Genetic Predisposition | 2013 |
Thiamine deficiency leads to reduced nitric oxide production and vascular dysfunction in rats.
Topics: Acetylcholine; Animals; Aorta; Hydrazines; Indomethacin; Male; Muscle Contraction; NG-Nitroarginine | 2014 |
Advanced glycation end products stimulate an enhanced neutrophil respiratory burst mediated through the activation of cytosolic phospholipase A2 and generation of arachidonic Acid.
Topics: Acetylcysteine; Adult; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Enzyme Inhibitors; Glyc | 2003 |
[Heterotopic ossification and vascular compression].
Topics: Adult; Craniocerebral Trauma; Etidronic Acid; Femoral Vein; Humans; Indomethacin; Male; Middle Aged; | 1994 |
The influence of diabetes on the vasomotor responses of saphenous vein and the development of infra-inguinal vein graft stenosis.
Topics: Aged; Aged, 80 and over; Amputation, Surgical; Blood Vessel Prosthesis; Bradykinin; Calcimycin; Coll | 1997 |
Organ culture: a new model for vascular endothelium dysfunction.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Apamin; | 2002 |
Hemodynamic, pulmonary vascular, and myocardial abnormalities secondary to pharmacologic constriction of the fetal ductus arteriosus. A possible mechanism for persistent pulmonary hypertension and transient tricuspid insufficiency in the newborn infant.
Topics: Animals; Blood Pressure; Blood Vessels; Constriction, Pathologic; Ductus Arteriosus; Fetal Heart; He | 1979 |
Fabry disease: ocular manifestations.
Topics: Adult; Aminoquinolines; Animals; Cataract; Child; Conjunctiva; Corneal Diseases; Corneal Opacity; Di | 1976 |
Prostaglandin F2 alpha and indomethacin in hepatogenic pulmonary angiodysplasia. Effects on pulmonary hemodynamics and gas exchange.
Topics: Aged; Dilatation, Pathologic; Dinoprost; Drug Therapy, Combination; Hemodynamics; Humans; Indomethac | 1991 |
Complement activation and membrane lipids in lung vascular injury.
Topics: Animals; Blood Vessels; Complement Activation; Complement C5; Complement C5a; Hemodynamics; Hypotens | 1987 |
Fibrinogen mediated activation of platelet aggregation and thromboxane A2 release: pathological implications in vascular disease.
Topics: Animals; Aorta; Blood Platelets; Epoprostenol; Female; Fibrinogen; Humans; In Vitro Techniques; Indo | 1985 |
[Vasculo-cutaneous anti-inflammatory drugs].
Topics: Anti-Inflammatory Agents; Antimalarials; Flavonoids; Humans; Indomethacin; Skin Diseases; Vascular D | 1967 |