indomethacin has been researched along with Tularemia in 1 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Tularemia: A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin treatment partially restored T cell proliferation and lowered IL-5 production to wild-type levels." | 1.34 | Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response. ( Drake, JR; Frelinger, JA; Hensley, LL; Jania, LA; Kawula, TH; Wilson, JE; Woolard, MD, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Woolard, MD | 1 |
| Wilson, JE | 1 |
| Hensley, LL | 1 |
| Jania, LA | 1 |
| Kawula, TH | 1 |
| Drake, JR | 1 |
| Frelinger, JA | 1 |
1 other study available for indomethacin and Tularemia
| Article | Year |
|---|---|
Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response.
Topics: Animals; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinopros | 2007 |