Page last updated: 2024-10-29

indomethacin and Tularemia

indomethacin has been researched along with Tularemia in 1 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Tularemia: A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin treatment partially restored T cell proliferation and lowered IL-5 production to wild-type levels."1.34Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response. ( Drake, JR; Frelinger, JA; Hensley, LL; Jania, LA; Kawula, TH; Wilson, JE; Woolard, MD, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Woolard, MD1
Wilson, JE1
Hensley, LL1
Jania, LA1
Kawula, TH1
Drake, JR1
Frelinger, JA1

Other Studies

1 other study available for indomethacin and Tularemia

ArticleYear
Francisella tularensis-infected macrophages release prostaglandin E2 that blocks T cell proliferation and promotes a Th2-like response.
    Journal of immunology (Baltimore, Md. : 1950), 2007, Feb-15, Volume: 178, Issue:4

    Topics: Animals; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinopros

2007