indomethacin has been researched along with Tricuspid Incompetence in 16 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ten pregnancies with 13 fetuses complicated by symptomatic polyhydramnios were treated with indomethacin." | 7.68 | Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ; Wasserstrum, N, 1990) |
| "To investigate the effects of indomethacin on the human fetal renal blood flow velocity waveform, 17 fetuses whose mothers were treated for preterm labor (N = 8) or polyhydramnios (N = 9) were studied." | 7.68 | Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios. ( Carpenter, RJ; Deter, RL; Kirshon, B; Mari, G; Moise, KJ, 1990) |
| " To mitigate the extent of CS and allow the pregnancy to continue, maternal non-steroidal anti-inflammatory drug (NSAID) therapy with indomethacin was started at 33 + 5 weeks to induce DA constriction." | 4.02 | Inadvertent irreversible closure of arterial duct following therapeutic use of transplacental indomethacin in a fetus with severe Ebstein's anomaly and circular shunt. ( Arbic, N; Gill, K; Honjo, O; Jaeggi, E; Ryan, G; Seed, M, 2021) |
| "Indomethacin was given for the treatment of preterm labor in a twin pregnancy at a dosage of 200 mg/day for 7 days beginning at 34 weeks and 5 days' gestation." | 3.68 | Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation. ( Ayres, NA; Hallak, M; Moise, KJ; Reiter, AA, 1991) |
| "Ten pregnancies with 13 fetuses complicated by symptomatic polyhydramnios were treated with indomethacin." | 3.68 | Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ; Wasserstrum, N, 1990) |
| "To investigate the effects of indomethacin on the human fetal renal blood flow velocity waveform, 17 fetuses whose mothers were treated for preterm labor (N = 8) or polyhydramnios (N = 9) were studied." | 3.68 | Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios. ( Carpenter, RJ; Deter, RL; Kirshon, B; Mari, G; Moise, KJ, 1990) |
| "Prenatally diagnosed Ebstein's anomaly with tricuspid valve dysplasia (EA/TVD) is a rare and high-risk congenital heart malformation with limited effective treatments." | 1.72 | Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy. ( Kraus, E; Lannaman, K; Powel, JE; Reddy, C, 2022) |
| " Initial dosing consisted of indomethacin, followed by ibuprofen in most cases." | 1.62 | Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly). ( Beroukhim, RS; Cumbermack, KM; Ferrer, Q; Freud, LR; Glickstein, JS; LaFranchi, T; Makhoul, M; Morris, SA; Pedra, SR; Phoon, CK; Sun, HY; Tworetzky, W; Wilkins-Haug, LE, 2021) |
| " The association of DA constriction and low BMI suggests that BMI-based dosing of indomethacin may be recommended for perioperative tocolysis in fetal MMC surgery." | 1.56 | Maternal low body mass index is a risk factor for fetal ductal constriction following indomethacin use among women undergoing fetal repair of spina bifida. ( Belfort, MA; Cortes, MS; Donado, MY; Erfani, H; Espinoza, J; Furtun, BY; Nassr, AA; Olutoye, O; Shamshirsaz, AA; Velez, MP; Whitehead, WE, 2020) |
| "We present a case of fetal hydrops associated with tricuspid regurgitation and ductal constriction developing within 30 hours of instituting indomethacin tocolysis in a 28-week singleton gestation." | 1.30 | Reversible fetal hydrops associated with indomethacin use. ( Digiosia, J; Martin, CB; Pratt, L; Swenson, JN; Trampe, B, 1997) |
| "Trivial tricuspid valve regurgitation was detected at a mean of 26." | 1.29 | Fetal echocardiography during indomethacin treatment. ( Huhta, JC; Respondek, M; Weil, SR, 1995) |
| "Indomethacin is a potent agent in the treatment of premature labor, but its use has been limited because of concern about its constrictive effects on the fetal ductus arteriosus." | 1.27 | Indomethacin in the treatment of premature labor. Effects on the fetal ductus arteriosus. ( Cano, L; Huhta, JC; Kirshon, B; Moise, KJ; Ou, CN; Sharif, DS; Wasserstrum, N, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 7 (43.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 5 (31.25) | 2.80 |
| Authors | Studies |
|---|---|
| Powel, JE | 1 |
| Kraus, E | 1 |
| Reddy, C | 1 |
| Lannaman, K | 1 |
| Nassr, AA | 1 |
| Furtun, BY | 1 |
| Cortes, MS | 1 |
| Erfani, H | 1 |
| Whitehead, WE | 1 |
| Donado, MY | 1 |
| Olutoye, O | 1 |
| Velez, MP | 1 |
| Espinoza, J | 1 |
| Belfort, MA | 1 |
| Shamshirsaz, AA | 1 |
| Hunter, L | 1 |
| Vigneswaran, TV | 1 |
| Pasupathy, D | 1 |
| Callaghan, N | 1 |
| Tenenbaum, J | 1 |
| Zidere, V | 1 |
| Simpson, JM | 1 |
| Freud, LR | 1 |
| Wilkins-Haug, LE | 1 |
| Beroukhim, RS | 1 |
| LaFranchi, T | 1 |
| Phoon, CK | 1 |
| Glickstein, JS | 1 |
| Cumbermack, KM | 1 |
| Makhoul, M | 1 |
| Morris, SA | 1 |
| Sun, HY | 1 |
| Ferrer, Q | 1 |
| Pedra, SR | 1 |
| Tworetzky, W | 1 |
| Gill, K | 1 |
| Arbic, N | 1 |
| Seed, M | 1 |
| Honjo, O | 1 |
| Ryan, G | 1 |
| Jaeggi, E | 1 |
| Respondek, M | 1 |
| Weil, SR | 1 |
| Huhta, JC | 2 |
| Takahashi, Y | 1 |
| Harada, K | 1 |
| Ishida, A | 1 |
| Tanaka, T | 1 |
| Tsuda, A | 1 |
| Takada, G | 1 |
| Pomeranz, A | 1 |
| Korzets, Z | 1 |
| Dolfin, Z | 1 |
| Eliakim, A | 1 |
| Bernheim, J | 1 |
| Wolach, B | 1 |
| Kumar, R | 1 |
| Sharma, YP | 1 |
| Gupta, I | 1 |
| Pratt, L | 1 |
| Digiosia, J | 1 |
| Swenson, JN | 1 |
| Trampe, B | 1 |
| Martin, CB | 1 |
| Levin, DL | 1 |
| Mills, LJ | 1 |
| Weinberg, AG | 1 |
| Hallak, M | 1 |
| Reiter, AA | 1 |
| Ayres, NA | 1 |
| Moise, KJ | 4 |
| Kirshon, B | 3 |
| Mari, G | 2 |
| Wasserstrum, N | 2 |
| Deter, RL | 1 |
| Carpenter, RJ | 1 |
| Sharif, DS | 1 |
| Ou, CN | 1 |
| Cano, L | 1 |
| Magny, JF | 1 |
| Petit, J | 1 |
| Saby, MA | 1 |
| Dehan, M | 1 |
| Gabilan, JC | 1 |
16 other studies available for indomethacin and Tricuspid Incompetence
| Article | Year |
|---|---|
Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ebstein Anomaly; Female; Fetal Diseases; Heart Defects, Con | 2022 |
Maternal low body mass index is a risk factor for fetal ductal constriction following indomethacin use among women undergoing fetal repair of spina bifida.
Topics: Adult; Body Mass Index; Cohort Studies; Constriction, Pathologic; Cyclooxygenase Inhibitors; Ductus | 2020 |
Effects and side effects of maternal administration of indomethacin for fetal tricuspid valve dysplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gestational Age; Heart Defects, Congenital; | 2021 |
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Ductus Arteriosus; Duration of Therapy; Ebste | 2021 |
Inadvertent irreversible closure of arterial duct following therapeutic use of transplacental indomethacin in a fetus with severe Ebstein's anomaly and circular shunt.
Topics: Administration, Oral; Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteri | 2021 |
Fetal echocardiography during indomethacin treatment.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Constriction, Pathologic; Ductus Arteriosus; Echoc | 1995 |
Doppler echocardiographic findings of indomethacin-induced occlusion of the fetal ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Cyclooxygenase Inhibitors; Dilatat | 1996 |
Acute renal failure in the neonate induced by the administration of indomethacin as a tocolytic agent.
Topics: Acute Kidney Injury; Adult; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn | 1996 |
Tricuspid regurgitation in a pair of twins at birth secondary to antenatal indomethacin.
Topics: Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Polyhydramnios; Pregnancy; Tocolyti | 2001 |
Reversible fetal hydrops associated with indomethacin use.
Topics: Adult; Ductus Arteriosus; Female; Humans; Hydrops Fetalis; Indomethacin; Pregnancy; Time Factors; To | 1997 |
Hemodynamic, pulmonary vascular, and myocardial abnormalities secondary to pharmacologic constriction of the fetal ductus arteriosus. A possible mechanism for persistent pulmonary hypertension and transient tricuspid insufficiency in the newborn infant.
Topics: Animals; Blood Pressure; Blood Vessels; Constriction, Pathologic; Ductus Arteriosus; Fetal Heart; He | 1979 |
Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation.
Topics: Abnormalities, Drug-Induced; Adult; Diseases in Twins; Drug Monitoring; Ductus Arteriosus; Female; F | 1991 |
Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios.
Topics: Ductus Arteriosus; Echocardiography; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Tricus | 1990 |
Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios.
Topics: Ductus Arteriosus; Female; Fetal Monitoring; Gestational Age; Humans; Indomethacin; Kidney; Maternal | 1990 |
Indomethacin in the treatment of premature labor. Effects on the fetal ductus arteriosus.
Topics: Adolescent; Adult; Constriction, Pathologic; Dose-Response Relationship, Drug; Ductus Arteriosus; Ec | 1988 |
[Maternal administration of indomethacin and neonatal tricuspid insufficiency].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Premature; Pregnancy; Tricuspi | 1987 |