Compounds > indomethacin
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indomethacin and Transposition of Great Vessels

indomethacin has been researched along with Transposition of Great Vessels in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Transposition of Great Vessels: A congenital cardiovascular malformation in which the AORTA arises entirely from the RIGHT VENTRICLE, and the PULMONARY ARTERY arises from the LEFT VENTRICLE. Consequently, the pulmonary and the systemic circulations are parallel and not sequential, so that the venous return from the peripheral circulation is re-circulated by the right ventricle via aorta to the systemic circulation without being oxygenated in the lungs. This is a potentially lethal form of heart disease in newborns and infants.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Drummond, WH1
Bucciarelli, RL1
Gessner, IH1
Heymann, MA2
Rudolph, AM1
Clyman, RI1

Reviews

2 reviews available for indomethacin and Transposition of Great Vessels

ArticleYear
The ductus arteriosus: why and how to manipulate its patency.
    The Journal of the Florida Medical Association, 1983, Volume: 70, Issue:9

    Topics: Alprostadil; Ductus Arteriosus, Patent; Gestational Age; Heart Defects, Congenital; Humans; Indometh

1983
Neonatal manipulation: patent ductus arteriosus.
    Cardiovascular clinics, 1981, Volume: 11, Issue:2

    Topics: Animals; Aorta, Thoracic; Ductus Arteriosus, Patent; Heart Defects, Congenital; Heart Ventricles; Hu

1981

Other Studies

1 other study available for indomethacin and Transposition of Great Vessels

ArticleYear
Pharmacology of the ductus arteriosus.
    Pediatric clinics of North America, 1981, Volume: 28, Issue:1

    Topics: Animals; Aorta, Thoracic; Cattle; Ductus Arteriosus; Ductus Arteriosus, Patent; Gestational Age; Hea

1981