Page last updated: 2024-10-29

indomethacin and Tongue Neoplasms

indomethacin has been researched along with Tongue Neoplasms in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Tongue Neoplasms: Tumors or cancer of the TONGUE.

Research Excerpts

ExcerptRelevanceReference
"Esophageal and tongue cancers have both been associated with dietary zinc deficiency (ZD), and cyclooxygenase (COX-2) is often overexpressed in these cancers."1.33Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. ( Farber, JL; Fong, LY; Jiang, Y; Zhang, L, 2005)
"Treatment with etretinate and in a later phase with indomethacin and prednisolone was not effective, except for a limited initial response of the tumour to etretinate."1.28Xeroderma pigmentosum: squamous cell carcinoma of the tongue. ( Keukens, F; Kleijer, WJ; Oosterhuis, JW; Panders, AK; van Voorst Vader, PC; Vinks, S, 1989)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's2 (25.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fong, LY1
Zhang, L1
Jiang, Y1
Farber, JL1
Scheper, MA1
Nikitakis, NG1
Sauk, JJ1
Tsao, SW1
Burman, JF1
Carter, RL1
ElAttar, TM2
Virji, AS1
Lin, HS2
Tanaka, T1
Nishikawa, A1
Mori, Y1
Morishita, Y1
Mori, H1
Keukens, F1
van Voorst Vader, PC1
Panders, AK1
Vinks, S1
Oosterhuis, JW1
Kleijer, WJ1
el Attar, TM1

Other Studies

8 other studies available for indomethacin and Tongue Neoplasms

ArticleYear
Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats.
    Journal of the National Cancer Institute, 2005, Jan-05, Volume: 97, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Blotting, Western; Carcinogens; Carcinoma, Squamous Ce

2005
Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer.
    International journal of oral and maxillofacial surgery, 2007, Volume: 36, Issue:7

    Topics: Annexin A5; Antineoplastic Agents; Apoptosis; Carcinoma, Squamous Cell; Celecoxib; Cell Division; Ce

2007
Hypercalcaemia and in vitro osteolysis associated with xenografts of squamous carcinomas of the tongue.
    British journal of cancer, 1983, Volume: 48, Issue:1

    Topics: Animals; Bone Resorption; Calcium; Carcinoma, Squamous Cell; Culture Techniques; Dinoprost; Dinopros

1983
Modulating effect of resveratrol and quercetin on oral cancer cell growth and proliferation.
    Anti-cancer drugs, 1999, Volume: 10, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents, Phytogenic; Antineoplastic Combined

1999
Effect of retinoids and carotenoids on prostaglandin formation by oral squamous carcinoma cells.
    Prostaglandins, leukotrienes, and essential fatty acids, 1991, Volume: 43, Issue:3

    Topics: beta Carotene; Canthaxanthin; Carcinoma, Squamous Cell; Carotenoids; Chromatography, Thin Layer; Fen

1991
Inhibitory effects of non-steroidal anti-inflammatory drugs, piroxicam and indomethacin on 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in male ACI/N rats.
    Cancer letters, 1989, Volume: 48, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Indomethacin; Male; Nitroquinolines; Ornithine Decarboxylase Inhi

1989
Xeroderma pigmentosum: squamous cell carcinoma of the tongue.
    Acta dermato-venereologica, 1989, Volume: 69, Issue:6

    Topics: Carcinoma, Squamous Cell; Child; Etretinate; Humans; Indomethacin; Male; Prednisolone; Tongue Neopla

1989
Prostaglandin synthesis by squamous carcinoma cells of head and neck, and its inhibition by non-steroidal anti-inflammatory drugs.
    Journal of oral pathology, 1987, Volume: 16, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acids; Aspirin; Carcinoma, Squamous Cell; Cell

1987