Page last updated: 2024-10-29

indomethacin and Temporomandibular Disorders

indomethacin has been researched along with Temporomandibular Disorders in 13 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Patients presenting with unilateral facial pain present a unique diagnostic challenge for dental practitioners."1.35Hemicrania continua presenting as temporomandibular joint pain. ( Stiles, A; Taub, D; Tucke, AG, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's6 (46.15)29.6817
2010's6 (46.15)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pelegrini-da-Silva, A2
Oliveira, MC2
Parada, CA3
Tambeli, CH3
Burgos, E1
Pascual, D1
Martín, MI1
Goicoechea, C1
Park, JW1
Chung, JW1
Cho, SH1
Whang, WW1
Oliveira-Fusaro, MC1
Clemente-Napimoga, JT1
Teixeira, JM1
Torres-Chávez, KE1
Noma, N1
Kamo, H1
Shimizu, K1
Plaza-Villegas, F1
Oka, S1
Imamura, Y1
Kawashima, M1
Ogura, N1
Akutsu, M1
Ito, K1
Kondoh, T1
Sarlani, E1
Schwartz, AH1
Greenspan, JD1
Grace, EG1
Rodrigues, LL1
de Arruda Veiga, MC1
Boulton, P1
Purdy, RA1
Bosch, EP1
Dodick, DW1
Thut, PD1
Hermanstyne, TO1
Flake, NM1
Gold, MS1
Taub, D1
Stiles, A1
Tucke, AG1
Benoliel, R1
Sharav, Y1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Cytokine and Growth Factor Changes and Correlation With Clinical Outcomes Following Acupuncture for TMD[NCT02324712]0 participants (Actual)InterventionalWithdrawn (stopped due to PI relocated to another institution; study may be resubmitted at a later date.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for indomethacin and Temporomandibular Disorders

ArticleYear
Acupuncture for temporomandibular disorders: a systematic review.
    Journal of orofacial pain, 2010,Spring, Volume: 24, Issue:2

    Topics: Acupuncture Therapy; Anti-Inflammatory Agents, Non-Steroidal; Humans; Indomethacin; Occlusal Splints

2010
Chronic paroxysmal hemicrania: a case report and review of the literature.
    Journal of orofacial pain, 2003,Winter, Volume: 17, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diagnosis, Differential; Female; Humans; I

2003
Paroxysmal hemicrania. Case studies and review of the literature.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 1998, Volume: 85, Issue:3

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cluster Headache; Conjunctiva

1998

Other Studies

10 other studies available for indomethacin and Temporomandibular Disorders

ArticleYear
Nerve growth factor acts with the beta2-adrenoceptor to induce spontaneous nociceptive behavior during temporomandibular joint inflammatory hyperalgesia.
    Life sciences, 2008, Dec-05, Volume: 83, Issue:23-24

    Topics: Adrenergic beta-2 Receptor Antagonists; Animals; Behavior, Animal; Carbazoles; Enzyme Inhibitors; Ep

2008
Antinociceptive effect of the cannabinoid agonist, WIN 55,212-2, in the orofacial and temporomandibular formalin tests.
    European journal of pain (London, England), 2010, Volume: 14, Issue:1

    Topics: Analgesics; Analgesics, Opioid; Anesthetics, Dissociative; Animals; Anti-Inflammatory Agents, Non-St

2010
Long-term treatment of Langerhans cell histiocytosis of the mandibular condyle with indomethacin.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2010, Volume: 109, Issue:4

    Topics: Abscess; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Infectious; Child; Diagnosis, Different

2010
5-HT induces temporomandibular joint nociception in rats through the local release of inflammatory mediators and activation of local β adrenoceptors.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 102, Issue:3

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroi

2012
Hemicrania continua in a patient with concomitant dental disease.
    Journal of the American Dental Association (1939), 2012, Volume: 143, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Dose-Response Relationship,

2012
The anti-inflammatory effect of cyclooxygenase inhibitors in fibroblast-like synoviocytes from the human temporomandibular joint results from the suppression of PGE2 production.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:6

    Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cell Culture Techniques; Cell

2013
Peripheral sympathetic component of the temporomandibular joint inflammatory pain in rats.
    The journal of pain, 2006, Volume: 7, Issue:12

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease

2006
Primary and secondary red ear syndrome: implications for treatment.
    Cephalalgia : an international journal of headache, 2007, Volume: 27, Issue:2

    Topics: Aged; Amines; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexanecarboxylic Acids; Ear

2007
An operant conditioning model to assess changes in feeding behavior associated with temporomandibular joint inflammation in the rat.
    Journal of orofacial pain, 2007,Winter, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; B

2007
Hemicrania continua presenting as temporomandibular joint pain.
    Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics, 2008, Volume: 105, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Diagnosis, Differential; Facial Pai

2008