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indomethacin and Tachycardia, Ventricular

indomethacin has been researched along with Tachycardia, Ventricular in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"The effects of aspirin and indomethacin on the ventricular arrhythmias produced by ligation (ischaemia) and unligation (reperfusion) of the circumflex branch of the left coronary vessel were evaluated in fifty male rabbits weighing 1."7.69Effects of aspirin and indomethacin on ventricular arrhythmias--comparative study. ( Bhatti, AS; Khan, HH, 1994)
"The perfusion with ibuprofen, indomethacin and diclofenac in commonly used doses raised the arrhythmia susceptibility in an established rabbit whole-heart model while APD shortening and shortened ERP seem to be crucial for arrhythmogenesis."4.12Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model. ( Bäumer, S; Eckardt, L; Ellermann, C; Fehr, M; Frommeyer, G; Leitz, PR; Wegner, F; Willy, K; Wolfes, J, 2022)
"The effects of aspirin and indomethacin on the ventricular arrhythmias produced by ligation (ischaemia) and unligation (reperfusion) of the circumflex branch of the left coronary vessel were evaluated in fifty male rabbits weighing 1."3.69Effects of aspirin and indomethacin on ventricular arrhythmias--comparative study. ( Bhatti, AS; Khan, HH, 1994)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Wolfes, J1
Ellermann, C1
Bäumer, S1
Fehr, M1
Willy, K1
Wegner, F1
Leitz, PR1
Eckardt, L1
Frommeyer, G1
Bhatti, AS1
Khan, HH1
Node, K1
Kitakaze, M1
Kosaka, H1
Minamino, T1
Funaya, H1
Hori, M1
Wang, L1

Other Studies

4 other studies available for indomethacin and Tachycardia, Ventricular

ArticleYear
Experimental evidence for proarrhythmic effects of nonsteroidal anti-inflammatory drugs in a sensitive whole-heart model.
    Basic & clinical pharmacology & toxicology, 2022, Volume: 130, Issue:1

    Topics: Action Potentials; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Cardiac E

2022
Effects of aspirin and indomethacin on ventricular arrhythmias--comparative study.
    JPMA. The Journal of the Pakistan Medical Association, 1994, Volume: 44, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; Aspirin; Blood Pressure; Cardiac Complexes, Premature; Cause of Death

1994
Amelioration of ischemia- and reperfusion-induced myocardial injury by 17beta-estradiol: role of nitric oxide and calcium-activated potassium channels.
    Circulation, 1997, Sep-16, Volume: 96, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Calcium; Dogs; Enzyme Inhibitors; Estradiol; Heart Ventricles; In

1997
The role of prostaglandins in the antiarrhythmic effect of ischemic preconditioning.
    Journal of biomedical science, 2001, Volume: 8, Issue:5

    Topics: Animals; Arrhythmias, Cardiac; Cardiovascular Agents; Electrocardiography; Heart Rate; Indomethacin;

2001