indomethacin has been researched along with Sunburn in 18 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Sunburn: An injury to the skin causing erythema, tenderness, and sometimes blistering and resulting from excessive exposure to the sun. The reaction is produced by the ultraviolet radiation in sunlight.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study we evaluated an assumptive anti-inflammatory effect of the nonsedative histamine H1-receptor antagonist, mizolastine, on UV-induced acute sunburn reaction." | 9.09 | UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin. ( Böckelmann, R; Bonnekoh, B; Gollnick, HP; Grundmann, JU, 2001) |
| "The inhibitory effects of topical indomethacin (IM)-treatment on sunburn and suntan reactions after ultraviolet (UV)-irradiation were investigated in the dorsal skin of hairless descendants of Mexican hairless dogs." | 7.70 | Effects of indomethacin on sunburn and suntan reactions in hairless descendants of Mexican hairless dogs. ( Doi, K; Kimura, T, 1998) |
| "The extent to which topical and intradermal corticosteroids and topical indomethacin suppress sunburn erythema was investigated in human volunteers." | 7.65 | The influence of corticosteroids and topical indomethacin on sunburn erythema. ( Kaidbey, KH; Kurban, AK, 1976) |
| " In this study we evaluated an assumptive anti-inflammatory effect of the nonsedative histamine H1-receptor antagonist, mizolastine, on UV-induced acute sunburn reaction." | 5.09 | UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin. ( Böckelmann, R; Bonnekoh, B; Gollnick, HP; Grundmann, JU, 2001) |
| "The inhibitory effects of topical indomethacin (IM)-treatment on sunburn and suntan reactions after ultraviolet (UV)-irradiation were investigated in the dorsal skin of hairless descendants of Mexican hairless dogs." | 3.70 | Effects of indomethacin on sunburn and suntan reactions in hairless descendants of Mexican hairless dogs. ( Doi, K; Kimura, T, 1998) |
| "5 per cent indomethacin (IM) solution to the sunburned skin of humans and guinea pigs resulted in a marked decrease in ultraviolet light (UVL) -induced erythema." | 3.65 | Cutaneous effects of topical indomethacin, an inhibitor of prostaglandin synthesis, on UV-damaged skin. ( Snyder, DS, 1975) |
| "The extent to which topical and intradermal corticosteroids and topical indomethacin suppress sunburn erythema was investigated in human volunteers." | 3.65 | The influence of corticosteroids and topical indomethacin on sunburn erythema. ( Kaidbey, KH; Kurban, AK, 1976) |
| " A skin biopsy was taken at 24 h after each dosing with UVB." | 2.67 | Synergistic effects of oral nonsteroidal drugs and topical corticosteroids in the therapy of sunburn in humans. ( Bohan, DF; Caruana, C; Francom, SF; Holland, M; Hughes, GS; Means, LK, 1992) |
| "Treatment with indomethacin, an inhibitor of prostaglandin (PG) synthesis, inhibited UV-induced inflammation and abrogated immunosuppression." | 1.31 | Photobiologic and photoimmunologic characteristics of XPA gene-deficient mice. ( Horiki, S; Horio, T; Kuwamoto, K; Miyauchi-Hashimoto, H; Okamoto, H; Tanaka, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 2 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pilkington, SM | 1 |
| Murphy, SA | 1 |
| Kudva, S | 1 |
| Nicolaou, A | 1 |
| Rhodes, LE | 1 |
| Nakamura, M | 1 |
| Haarmann-Stemmann, T | 1 |
| Krutmann, J | 1 |
| Lim, HW | 1 |
| Thorbecke, GJ | 1 |
| Baer, RL | 1 |
| Gigli, I | 1 |
| Sloan, KB | 1 |
| Selk, S | 1 |
| Haslam, J | 1 |
| Caldwell, L | 1 |
| Shaffer, R | 1 |
| Gschnait, F | 2 |
| Schwarz, T | 1 |
| Seiser, A | 1 |
| Kimura, T | 1 |
| Doi, K | 1 |
| Grundmann, JU | 1 |
| Böckelmann, R | 1 |
| Bonnekoh, B | 1 |
| Gollnick, HP | 1 |
| Horio, T | 1 |
| Miyauchi-Hashimoto, H | 1 |
| Kuwamoto, K | 1 |
| Horiki, S | 1 |
| Okamoto, H | 1 |
| Tanaka, K | 1 |
| Peters, P | 1 |
| Cooper, C | 1 |
| Maiorana, K | 1 |
| Graeme, ML | 1 |
| Holý, B | 1 |
| Faberová, J | 1 |
| Pehamberger, H | 1 |
| Weirich, EG | 1 |
| Lutz, UC | 1 |
| Snyder, DS | 3 |
| Eaglstein, WH | 2 |
| Kaidbey, KH | 1 |
| Kurban, AK | 1 |
| Hughes, GS | 1 |
| Francom, SF | 1 |
| Means, LK | 1 |
| Bohan, DF | 1 |
| Caruana, C | 1 |
| Holland, M | 1 |
3 trials available for indomethacin and Sunburn
| Article | Year |
|---|---|
UV erythema reducing capacity of mizolastine compared to acetylsalicylic acid or both combined in comparison to indomethacin.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Benzimidazoles; Cells, Cultured | 2001 |
Synergistic effects of oral nonsteroidal drugs and topical corticosteroids in the therapy of sunburn in humans.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Betameth | 1992 |
Topical indomethacin and sunburn.
Topics: Acetates; Administration, Topical; Adult; Anti-Inflammatory Agents; Evaluation Studies as Topic; Flu | 1974 |
15 other studies available for indomethacin and Sunburn
| Article | Year |
|---|---|
COX inhibition reduces vasodilator PGE2 but is shown to increase levels of chemoattractant 12-HETE in vivo in human sunburn.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Adult; Cyclooxygenase Inhibitors; Dinoprostone; Female; | 2015 |
COX inhibition enhances inflammatory immune cell infiltration in UV-irradiated human skin: implications for the treatment of sunburn.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Cyclooxygenase Inhibitors; Dinoprostone; Female; Humans; | 2015 |
Effect of indomethacin on alteration of ATPase-positive Langerhans cell density and cutaneous sunburn reaction induced by ultraviolet-B radiation.
Topics: 4-Aminobenzoic Acid; Adenosine Triphosphatases; Administration, Topical; Animals; Guinea Pigs; Indom | 1983 |
Acyloxyamines as prodrugs of anti-inflammatory carboxylic acids for improved delivery through skin.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents; Burns; Carboxylic Acids; Chemical Phenom | 1984 |
Topical indomethacin protects from UVB and UVA irradiation.
Topics: Administration, Topical; Dose-Response Relationship, Radiation; Humans; Indomethacin; Sunburn; Ultra | 1984 |
Effects of indomethacin on sunburn and suntan reactions in hairless descendants of Mexican hairless dogs.
Topics: Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dinoprostone; Dogs; Femal | 1998 |
Photobiologic and photoimmunologic characteristics of XPA gene-deficient mice.
Topics: Animals; Apyrase; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dermatit | 2001 |
The effect of topically applied agents on ultraviolet erythema in guinea pigs.
Topics: 4-Aminobenzoic Acid; Administration, Topical; Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhi | 1977 |
[Antiphlogistic effect of indomethacin in local therapy (author's transl)].
Topics: Adult; Anti-Inflammatory Agents; Betamethasone Valerate; Humans; Indomethacin; Phenylbutazone; Skin; | 1978 |
Indomethacin does not affect PUVA induced erythema.
Topics: Adult; Humans; Indomethacin; Methoxsalen; Sunburn; Ultraviolet Rays | 1977 |
[Inhibition of ultraviolet irradiation response of human skin by topical phlogostatic compounds (author's transl)].
Topics: Bufexamac; Flumethasone; Fluocinolone Acetonide; Humans; Hydrocortisone; Indomethacin; Oxyphenbutazo | 1977 |
Effect of topical indomethacin on UVR-induced redness and prostaglandin E levels in sunburned guinea pig skin.
Topics: Administration, Topical; Animals; Female; Guinea Pigs; Indomethacin; Prostaglandins E; Radiation Inj | 1976 |
Cutaneous effects of topical indomethacin, an inhibitor of prostaglandin synthesis, on UV-damaged skin.
Topics: Administration, Topical; Animals; Cell Survival; Depression, Chemical; DNA; Erythema; Female; Guinea | 1975 |
Indomethacin: treatment for sunburn or investigative tool in ultraviolet inflammation?
Topics: Indomethacin; Sunburn; Ultraviolet Rays | 1975 |
The influence of corticosteroids and topical indomethacin on sunburn erythema.
Topics: Administration, Topical; Adult; Betamethasone; Betamethasone Valerate; Humans; Indomethacin; Injecti | 1976 |