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indomethacin and Suffocation

indomethacin has been researched along with Suffocation in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"The response of circulating catecholamines to asphyxia in unanesthetized, spontaneously breathing neonatal piglets was measured before and after treatment with indomethacin."7.67Indomethacin does not alter the circulating catecholamine response to asphyxia in the neonatal piglet. ( Beasley, DG; Busija, DW; Fletcher, AM; Green, RS; Leffler, CW, 1987)
"We determined the effect of breathing 9% CO2/10% O2/81% N2 (asphyxia) on cardiac output distribution (microspheres) in 4-5 day old unanesthetized, chronically instrumented piglets prior to and following intravenous indomethacin administration."7.67Effects of indomethacin on cardiac output distribution in normal and asphyxiated piglets. ( Beasley, DG; Busija, DW; Fletcher, AM; Green, RS; Leffler, CW, 1986)
"Cerebral hemodynamics during asphyxia and reventilation were investigated in normothermic, hypothermic (35 degrees C), and indomethacin-pretreated (5 mg/kg iv) anesthetized, newborn pigs."3.68Role of prostanoids in cerebrovascular responses to asphyxia and reventilation in newborn pigs. ( Busija, D; Leffler, C; Pourcyrous, M, 1990)
"The response of circulating catecholamines to asphyxia in unanesthetized, spontaneously breathing neonatal piglets was measured before and after treatment with indomethacin."3.67Indomethacin does not alter the circulating catecholamine response to asphyxia in the neonatal piglet. ( Beasley, DG; Busija, DW; Fletcher, AM; Green, RS; Leffler, CW, 1987)
"We determined the effect of breathing 9% CO2/10% O2/81% N2 (asphyxia) on cardiac output distribution (microspheres) in 4-5 day old unanesthetized, chronically instrumented piglets prior to and following intravenous indomethacin administration."3.67Effects of indomethacin on cardiac output distribution in normal and asphyxiated piglets. ( Beasley, DG; Busija, DW; Fletcher, AM; Green, RS; Leffler, CW, 1986)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19904 (66.67)18.7374
1990's2 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, LG1
Louis, TM1
Kopelman, AE1
Pourcyrous, M2
Leffler, CW4
Mirro, R1
Busija, DW4
Leffler, C1
Busija, D1
Brooks, DP1
Crofton, JT1
Share, L1
Beasley, DG3
Fletcher, AM3
Green, RS2

Other Studies

6 other studies available for indomethacin and Suffocation

ArticleYear
Brain prostaglandins E2 and F2 alpha following neonatal asphyxia in the guinea pig.
    Biology of the neonate, 1982, Volume: 42, Issue:1-2

    Topics: Animals; Animals, Newborn; Apnea; Asphyxia; Brain Chemistry; Guinea Pigs; Indomethacin; Prostaglandi

1982
Brain superoxide anion generation during asphyxia and reventilation in newborn pigs.
    Pediatric research, 1990, Volume: 28, Issue:6

    Topics: Animals; Animals, Newborn; Asphyxia; Brain; Female; Indomethacin; Male; Nitroblue Tetrazolium; Super

1990
Role of prostanoids in cerebrovascular responses to asphyxia and reventilation in newborn pigs.
    The American journal of physiology, 1990, Volume: 259, Issue:3 Pt 2

    Topics: Animals; Animals, Newborn; Asphyxia; Cerebrovascular Circulation; Female; Humans; Indomethacin; Male

1990
Vasopressin responses to asphyxia and hemorrhage in newborn pigs.
    The American journal of physiology, 1987, Volume: 252, Issue:1 Pt 2

    Topics: Animals; Animals, Newborn; Asphyxia; Blood Pressure; Carbon Dioxide; Hemorrhage; Hydrogen-Ion Concen

1987
Indomethacin does not alter the circulating catecholamine response to asphyxia in the neonatal piglet.
    Pediatric research, 1987, Volume: 21, Issue:6

    Topics: Animals; Animals, Newborn; Asphyxia; Blood Pressure; Catecholamines; Dopamine; Epinephrine; Hydrogen

1987
Effects of indomethacin on cardiac output distribution in normal and asphyxiated piglets.
    Prostaglandins, 1986, Volume: 31, Issue:2

    Topics: Animals; Animals, Newborn; Asphyxia; Cardiac Output; Indomethacin; Organ Specificity; Regional Blood

1986