Page last updated: 2024-10-29

indomethacin and Sprains

indomethacin has been researched along with Sprains in 10 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Seventy-eight patients, aged 12-87 years, with osteoarthritis or extremity trauma, attached one indomethacin patch (containing 96 mg indomethacin) to the most symptomatic site twice daily."9.08Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma. ( Hatori, M; Kokubun, S, 1997)
"In a controlled randomized double-blind study, the effectiveness and tolerance of two gels containing the active substance indomethacin used in the treatment of acute sprains of the ankle were compared."9.07[Treatment of acute ankle sprains. Comparison of the efficacy and tolerance of 2 indomethacin-gel preparations]. ( Diebschlag, W; Lehmacher, W; Nocker, W, 1992)
"Seventy-eight patients, aged 12-87 years, with osteoarthritis or extremity trauma, attached one indomethacin patch (containing 96 mg indomethacin) to the most symptomatic site twice daily."5.08Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma. ( Hatori, M; Kokubun, S, 1997)
"In a controlled randomized double-blind study, the effectiveness and tolerance of two gels containing the active substance indomethacin used in the treatment of acute sprains of the ankle were compared."5.07[Treatment of acute ankle sprains. Comparison of the efficacy and tolerance of 2 indomethacin-gel preparations]. ( Diebschlag, W; Lehmacher, W; Nocker, W, 1992)
"Pain threshold increased after treatment, and was significantly increased in the loxoprofen-Na group compared with the control group (p < 0."3.74Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model. ( Kikuchi, S; Konno, S; Sekiguchi, M; Shirasaka, M, 2008)
" 92 patients received piroxicam in a daily dosage of 4 capsules (40 mg) during the first two days, then 20 mg during the following days."2.65Double blind comparative study of piroxicam and indomethacin in acute locomotor affections linked with sports activity. ( Commandre, F, 1983)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19905 (50.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kim, HY1
Wang, J1
Chung, K1
Chung, JM1
Sekiguchi, M1
Shirasaka, M1
Konno, S1
Kikuchi, S1
Commandre, F1
Oian, P1
Kleive, I1
Lereim, P1
Hatori, M1
Kokubun, S1
Pulido, Z1
González, E1
Alfaya, T1
Alvarez, JA1
Ceña, M1
de la Hoz, B1
Diebschlag, W1
Nocker, W1
Lehmacher, W1
Machtey, I1
Stucke, K1
Brüner, M1
Brzoska, U1
Engelhardt, G1

Trials

5 trials available for indomethacin and Sprains

ArticleYear
Double blind comparative study of piroxicam and indomethacin in acute locomotor affections linked with sports activity.
    European journal of rheumatology and inflammation, 1983, Volume: 6, Issue:1

    Topics: Adult; Aging; Anti-Inflammatory Agents; Athletic Injuries; Clinical Trials as Topic; Double-Blind Me

1983
[Indomethacin in acute ankle torsion].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1981, Jan-10, Volume: 101, Issue:1B

    Topics: Adult; Ankle Injuries; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin;

1981
Clinical evaluation of indomethacin-containing patches for osteoarthritis and extremity trauma.
    Current medical research and opinion, 1997, Volume: 13, Issue:9

    Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non

1997
[Treatment of acute ankle sprains. Comparison of the efficacy and tolerance of 2 indomethacin-gel preparations].
    Fortschritte der Medizin, 1992, Feb-28, Volume: 110, Issue:6

    Topics: Administration, Topical; Adolescent; Adult; Ankle Injuries; Double-Blind Method; Female; Gels; Human

1992
[Indometacin in athletic injuries and overstrain].
    Munchener medizinische Wochenschrift (1950), 1972, Dec-08, Volume: 114, Issue:49

    Topics: Adult; Athletic Injuries; Blood Pressure; Cardiac Output; Electrocardiography; Female; Humans; Indom

1972

Other Studies

5 other studies available for indomethacin and Sprains

ArticleYear
A surgical ankle sprain pain model in the rat: effects of morphine and indomethacin.
    Neuroscience letters, 2008, Sep-12, Volume: 442, Issue:2

    Topics: Analgesics, Opioid; Analysis of Variance; Animals; Ankle Injuries; Anti-Inflammatory Agents, Non-Ste

2008
Analgesic effect of percutaneously absorbed non-steroidal anti-inflammatory drugs: an experimental study in a rat acute inflammation model.
    BMC musculoskeletal disorders, 2008, Jan-31, Volume: 9

    Topics: Acute Disease; Administration, Topical; Animals; Anti-Inflammatory Agents, Non-Steroidal; Contusions

2008
Allergic contact dermatitis from indomethacin.
    Contact dermatitis, 1999, Volume: 41, Issue:2

    Topics: Adolescent; Ankle Injuries; Anti-Inflammatory Agents, Non-Steroidal; Dermatitis, Allergic Contact; D

1999
Editorial: Pain relief in minor musculoskeletal disorders.
    British medical journal, 1976, May-29, Volume: 1, Issue:6021

    Topics: Aspirin; Athletic Injuries; Dimethyl Sulfoxide; Humans; Indomethacin; Pain; Sprains and Strains

1976
Diclofenac in the treatment of painful joints and traumatic tendinitis (including strains and sprains): a brief review.
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:2 Suppl 1

    Topics: Diclofenac; Flufenamic Acid; Humans; Ibuprofen; Indomethacin; Joint Diseases; Ketoprofen; Naproxen;

1985