Page last updated: 2024-10-29

indomethacin and Schwartzman Phenomenon

indomethacin has been researched along with Schwartzman Phenomenon in 6 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin has this effect if given before the first but not the second injection of endotoxin."1.26The effects of indomethacin on the generalized shwartzman reaction. ( Howes, EL; Kwok, MT; McKay, DG, 1978)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19906 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Howes, EL1
Kwok, MT1
McKay, DG1
Latour, JG1
Leger-Gauthier, C1
Shim, BS1
Kim, IK1
Herman, AJ1
Nakanishi, M1
Goto, K1
Van Arman, CG1
Carlson, RP1
Brown, WR1
Itkin, A1

Other Studies

6 other studies available for indomethacin and Schwartzman Phenomenon

ArticleYear
The effects of indomethacin on the generalized shwartzman reaction.
    The American journal of pathology, 1978, Volume: 90, Issue:1

    Topics: Animals; Bacterial Toxins; Blood Cell Count; Blood Coagulation; Endotoxins; Escherichia coli; Female

1978
Prostaglandins in the pathogenesis of the generalized Shwartzman reaction.
    American journal of obstetrics and gynecology, 1979, Nov-01, Volume: 135, Issue:5

    Topics: Animals; Aspirin; Bradykinin; Cortisone; Endotoxins; Female; Indomethacin; Male; Pregnancy; Prostagl

1979
Local Shwartzman-like phenomenon prepared with haptoglobin-hemoglobin complex and provoked with prostaglandin.
    Vox sanguinis, 1978, Volume: 35, Issue:6

    Topics: Animals; Endotoxins; Haptoglobins; Hemoglobins; Indomethacin; Injections, Intradermal; Prostaglandin

1978
Proceedings: Release of prostaglandins in the knee joint of the dog during local Shwartzman-like reaction.
    British journal of pharmacology, 1975, Volume: 55, Issue:2

    Topics: Animals; Concanavalin A; Dogs; Endotoxins; Female; Indomethacin; Knee Joint; Male; Prostaglandins; S

1975
[Studies on anti-inflammatory agents. XXVI. Effect on local Shwartzman reaction in rabbits (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1974, Volume: 94, Issue:11

    Topics: Animals; Anti-Inflammatory Agents; Indomethacin; Male; Rabbits; Shwartzman Phenomenon; Xanthenes

1974
Indomethacin inhibits the local Shwartzman reaction.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1970, Volume: 134, Issue:1

    Topics: Animals; Depression, Chemical; Endotoxins; Indomethacin; Neutrophils; Rabbits; Shwartzman Phenomenon

1970