indomethacin has been researched along with Schwartzman Phenomenon in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin has this effect if given before the first but not the second injection of endotoxin." | 1.26 | The effects of indomethacin on the generalized shwartzman reaction. ( Howes, EL; Kwok, MT; McKay, DG, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howes, EL | 1 |
| Kwok, MT | 1 |
| McKay, DG | 1 |
| Latour, JG | 1 |
| Leger-Gauthier, C | 1 |
| Shim, BS | 1 |
| Kim, IK | 1 |
| Herman, AJ | 1 |
| Nakanishi, M | 1 |
| Goto, K | 1 |
| Van Arman, CG | 1 |
| Carlson, RP | 1 |
| Brown, WR | 1 |
| Itkin, A | 1 |
6 other studies available for indomethacin and Schwartzman Phenomenon
| Article | Year |
|---|---|
The effects of indomethacin on the generalized shwartzman reaction.
Topics: Animals; Bacterial Toxins; Blood Cell Count; Blood Coagulation; Endotoxins; Escherichia coli; Female | 1978 |
Prostaglandins in the pathogenesis of the generalized Shwartzman reaction.
Topics: Animals; Aspirin; Bradykinin; Cortisone; Endotoxins; Female; Indomethacin; Male; Pregnancy; Prostagl | 1979 |
Local Shwartzman-like phenomenon prepared with haptoglobin-hemoglobin complex and provoked with prostaglandin.
Topics: Animals; Endotoxins; Haptoglobins; Hemoglobins; Indomethacin; Injections, Intradermal; Prostaglandin | 1978 |
Proceedings: Release of prostaglandins in the knee joint of the dog during local Shwartzman-like reaction.
Topics: Animals; Concanavalin A; Dogs; Endotoxins; Female; Indomethacin; Knee Joint; Male; Prostaglandins; S | 1975 |
[Studies on anti-inflammatory agents. XXVI. Effect on local Shwartzman reaction in rabbits (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Indomethacin; Male; Rabbits; Shwartzman Phenomenon; Xanthenes | 1974 |
Indomethacin inhibits the local Shwartzman reaction.
Topics: Animals; Depression, Chemical; Endotoxins; Indomethacin; Neutrophils; Rabbits; Shwartzman Phenomenon | 1970 |