indomethacin has been researched along with Schistosoma mansoni Infection in 9 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indomethacin treatment led to distortion of hepatic cell arrangement as well as marked cellular infiltration and congestion." | 5.29 | Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure. ( Abdel-Wahab, MM; Bayoumy, AS; Hassounah, OA, 1995) |
| "Indomethacin treatment led to distortion of hepatic cell arrangement as well as marked cellular infiltration and congestion." | 1.29 | Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure. ( Abdel-Wahab, MM; Bayoumy, AS; Hassounah, OA, 1995) |
| "mansoni eggs in patients with chronic intestinal schistosomiasis and do so by inducing macrophages to secrete prostaglandins." | 1.28 | Granulomatous hypersensitivity to Schistosoma mansoni egg antigens in human schistosomiasis. III. In vitro granuloma modulation induced by immune complexes. ( Doughty, BL; Gazzinelli, G; Goes, AM; Katz, N; Rocha, R, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martin, F | 1 |
| Penet, MF | 1 |
| Malergue, F | 1 |
| Lepidi, H | 1 |
| Dessein, A | 1 |
| Galland, F | 1 |
| de Reggi, M | 1 |
| Naquet, P | 1 |
| Gharib, B | 1 |
| Hassounah, OA | 1 |
| Bayoumy, AS | 1 |
| Abdel-Wahab, MM | 1 |
| Aloe, L | 1 |
| Moroni, R | 1 |
| Angelucci, F | 1 |
| Fiore, M | 1 |
| Goes, AM | 1 |
| Gazzinelli, G | 1 |
| Rocha, R | 1 |
| Katz, N | 1 |
| Doughty, BL | 1 |
| Elliott, DE | 2 |
| Ragheb, S | 1 |
| Wellhausen, SR | 1 |
| Boros, DL | 2 |
| Gastl, GA | 1 |
| Feldmeier, H | 1 |
| Kortmann, C | 1 |
| Daffalla, AA | 1 |
| Peter, HH | 1 |
| Kelly, EA | 1 |
| Colley, DG | 1 |
| Righthand, VF | 1 |
| Remick, DG | 1 |
| Kunkel, SL | 1 |
| Higashi, GI | 1 |
| Hiserodt, JC | 1 |
9 other studies available for indomethacin and Schistosoma mansoni Infection
| Article | Year |
|---|---|
Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores.
Topics: Amidohydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion Molecules; Chemokin | 2004 |
Studies on the effect of acute doses of indomethacin (prostaglandins inhibitor) during induced liver failure.
Topics: Animals; Carbon Tetrachloride Poisoning; Dose-Response Relationship, Drug; Indomethacin; Kidney Func | 1995 |
Role of TNF-alpha but not NGF in murine hyperalgesia induced by parasitic infection.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Degranulation; Female; Hyperalgesia; Indometh | 1997 |
Granulomatous hypersensitivity to Schistosoma mansoni egg antigens in human schistosomiasis. III. In vitro granuloma modulation induced by immune complexes.
Topics: Alprostadil; Animals; Antibodies; Antibodies, Helminth; Antigen-Antibody Complex; Antigens, Helminth | 1991 |
Interactions between adherent mononuclear cells and lymphocytes from granulomas of mice with schistosomiasis mansoni.
Topics: Animals; Antigens, Helminth; Concanavalin A; Granuloma; Immune Tolerance; Indomethacin; Interferon T | 1990 |
Human schistosomiasis: deficiency of large granular lymphocytes and indomethacin-sensitive suppression of natural killing.
Topics: Child; Humans; Immune Tolerance; Indomethacin; Interferons; Killer Cells, Natural; Lymphocytes; Schi | 1986 |
Effects of immunomanipulations on resistance induced by irradiated Schistosoma mansoni cercarial sensitization of C57BL/6 and CBA/J mice.
Topics: Animals; Cimetidine; Cyclophosphamide; Female; Immunity, Innate; Immunization; Indomethacin; Male; M | 1986 |
Characterization of regulatory (interferon-alpha/beta) and accessory (LAF/IL 1) monokine activities from liver granuloma macrophages of Schistosoma mansoni-infected mice.
Topics: Animals; Antigens, Helminth; Antiviral Agents; Female; Granuloma; Indomethacin; Interferon Type I; I | 1987 |
Suppression of natural killer cytolytic activity in mice undergoing pulmonary granulomatous inflammation.
Topics: Animals; Cytotoxicity, Immunologic; Foreign-Body Reaction; Granuloma; Immune Tolerance; Indomethacin | 1988 |