indomethacin has been researched along with Sarcoma in 6 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Sarcoma: A connective tissue neoplasm formed by proliferation of mesodermal cells; it is usually highly malignant.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An infant presented with a non-metastatic renal spindle cell sarcoma and hypercalcaemia, which resolved after treatment with indomethacin." | 7.68 | Indomethacin responsive hypercalcaemia associated with a renal sarcoma. ( Dillon, MJ; Gibbs, J; Lang, S; Meghji, S; Pritchard, J, 1990) |
| " The direct cytotoxicity of piroxicam indomethacin, and aspirin against 4 canine tumor cell lines (transitional cell carcinoma, squamous cell carcinoma, melanoma, and soft tissue sarcoma) was determined in short-term growth rate assays and in clonogenic assays." | 3.69 | Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells. ( Chan, TC; Knapp, DW; Kuczek, T; Park, B; Reagan, WJ, 1995) |
| "An infant presented with a non-metastatic renal spindle cell sarcoma and hypercalcaemia, which resolved after treatment with indomethacin." | 3.68 | Indomethacin responsive hypercalcaemia associated with a renal sarcoma. ( Dillon, MJ; Gibbs, J; Lang, S; Meghji, S; Pritchard, J, 1990) |
| "The responses to Concanavalin A (Con A) of peripheral blood mononuclear cells were studied in 22 patients with malignant bone and soft tissue sarcoma." | 3.66 | [Studies on the suppressor cells acting on the mitogen induced blastogenesis in tumor-bearing hosts. II. Suppressor cells in the peripheral blood of patients with malignant bone and soft tissue sarcoma (author's transl)]. ( Takami, M, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takami, M | 1 |
| Knapp, DW | 1 |
| Chan, TC | 1 |
| Kuczek, T | 1 |
| Reagan, WJ | 1 |
| Park, B | 1 |
| Huang, P | 1 |
| Allam, A | 1 |
| Taghian, A | 1 |
| Ruka, W | 1 |
| Freeman, J | 1 |
| Duffy, M | 1 |
| Suit, HD | 1 |
| Gibbs, J | 1 |
| Dillon, MJ | 1 |
| Lang, S | 1 |
| Meghji, S | 1 |
| Pritchard, J | 1 |
| Jaffe, BM | 1 |
| Liotta, S | 1 |
| Ronchi, F | 1 |
1 review available for indomethacin and Sarcoma
| Article | Year |
|---|---|
Prostaglandins and cancer: an update.
Topics: Animals; Aspirin; Bucladesine; Calcium; Carcinoma; Cell Division; Cell Line; Depression, Chemical; H | 1974 |
5 other studies available for indomethacin and Sarcoma
| Article | Year |
|---|---|
[Studies on the suppressor cells acting on the mitogen induced blastogenesis in tumor-bearing hosts. II. Suppressor cells in the peripheral blood of patients with malignant bone and soft tissue sarcoma (author's transl)].
Topics: Bone Neoplasms; Cell Adhesion; Concanavalin A; Humans; Indomethacin; Monocytes; Sarcoma; Soft Tissue | 1980 |
Evaluation of in vitro cytotoxicity of nonsteroidal anti-inflammatory drugs against canine tumor cells.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Aspirin; Carcinoma, Squamou | 1995 |
Quantitative comparison of xenotransplantation of a human soft tissue sarcoma into the subcutaneous tissue of normal, postincision, and postincision plus indomethacin-treated nude mice.
Topics: Animals; Dermatologic Surgical Procedures; Female; Humans; Indomethacin; Male; Mice; Mice, Nude; Neo | 1995 |
Indomethacin responsive hypercalcaemia associated with a renal sarcoma.
Topics: Combined Modality Therapy; Dinoprostone; Humans; Hypercalcemia; Indomethacin; Infant; Kidney Neoplas | 1990 |
[Antipyretic activity of indomethacin in histiocytic sarcomatosis of a systemic type].
Topics: Adolescent; Adult; Aged; Female; Histiocytes; Hodgkin Disease; Humans; Indomethacin; Leukemia; Male; | 1967 |