indomethacin has been researched along with Rhinitis in 7 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Rhinitis: Inflammation of the NASAL MUCOSA, the mucous membrane lining the NASAL CAVITIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 7.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| "Starting with the weak agonist indomethacin, a series of potent, selective CRTh2 (DP(2)) antagonists have been discovered as potential treatments for asthma, allergic rhinitis and other inflammatory diseases." | 3.73 | Discovery of potent CRTh2 (DP2) receptor antagonists. ( Arrowsmith, EC; Beech, C; Bell, FM; Birkinshaw, TN; Bonnert, RV; Carrillo, JJ; Dougall, IG; Hill, S; Paine, SW; Patel, A; Phillips, TT; Reakes, S; Salter, S; Sanganee, H; Schmidt, J; Teague, SJ; Weaver, R, 2006) |
| "Eleven patients with asthma and aspirin hypersensitivity have been challenged with eight non-steroidal anti-inflammatory drugs." | 3.65 | Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. ( Czerniawska-Mysik, G; Gryglewski, RJ; Szczeklik, A, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Birkinshaw, TN | 1 |
| Teague, SJ | 1 |
| Beech, C | 1 |
| Bonnert, RV | 1 |
| Hill, S | 1 |
| Patel, A | 1 |
| Reakes, S | 1 |
| Sanganee, H | 1 |
| Dougall, IG | 1 |
| Phillips, TT | 1 |
| Salter, S | 1 |
| Schmidt, J | 1 |
| Arrowsmith, EC | 1 |
| Carrillo, JJ | 1 |
| Bell, FM | 1 |
| Paine, SW | 1 |
| Weaver, R | 1 |
| Rahman, A | 1 |
| Yatsuzuka, R | 1 |
| Jiang, S | 1 |
| Ueda, Y | 1 |
| Kamei, C | 1 |
| Benoliel, R | 1 |
| Sharav, Y | 1 |
| Szczeklik, A | 1 |
| Gryglewski, RJ | 1 |
| Czerniawska-Mysik, G | 1 |
| Fisherman, EW | 1 |
| Cohen, GN | 1 |
| Samter, M | 1 |
| Beers, RF | 1 |
| Haff, RF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Challenge Test for Acetylsalicylic Acid Hypersensitivity[NCT01681615] | 50 participants (Anticipated) | Interventional | 2012-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for indomethacin and Rhinitis
| Article | Year |
|---|---|
Paroxysmal hemicrania. Case studies and review of the literature.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cluster Headache; Conjunctiva | 1998 |
6 other studies available for indomethacin and Rhinitis
| Article | Year |
|---|---|
Discovery of potent CRTh2 (DP2) receptor antagonists.
Topics: Asthma; Chemistry, Pharmaceutical; Drug Design; Humans; Indomethacin; Inflammation; Inhibitory Conce | 2006 |
Involvement of cyclooxygenase-2 in allergic nasal inflammation in rats.
Topics: Animals; Carbazoles; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Electroenc | 2006 |
Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients.
Topics: Adult; Aged; Analgesics; Aspirin; Asthma; Bronchi; Drug Hypersensitivity; Female; Flufenamic Acid; H | 1975 |
Aspirin and other cross-reacting small chemicals in known aspirin intolerant patients.
Topics: Analgesics; Antioxidants; Aspirin; Asthma; Blood Coagulation; Cross Reactions; Dose-Response Relatio | 1973 |
Concerning the nature of intolerance to aspirin.
Topics: Aminopyrine; Antipyrine; Aspirin; Asthma; Chemoreceptor Cells; Drug Hypersensitivity; Edema; Histami | 1967 |
Symptomatic therapy of influenza rhinitis in ferrets by topical application of compounds.
Topics: Airway Resistance; Animals; Anti-Inflammatory Agents; Capillary Permeability; Carnivora; Cresols; Cy | 1970 |