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indomethacin and Rhinitis, Allergic, Nonseasonal

indomethacin has been researched along with Rhinitis, Allergic, Nonseasonal in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis."7.66Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981)
"To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis."3.66Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981)
"However, indomethacin-induced nasal blockage was not provoked in non-sensitized animals."1.34Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis. ( Fujii, M; Han, HY; Kohno, S; Mizutani, N; Nabe, T; Takenaka, H; Terada, T, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pettipher, R1
Whittaker, M1
Han, HY1
Nabe, T1
Mizutani, N1
Fujii, M1
Terada, T1
Takenaka, H1
Kohno, S1
Lumry, WR1
Curd, JG1
Zeiger, RS1
Pleskow, WW1
Stevenson, DD1
Fish, JE1
Ankin, MG1
Adkinson, NF1
Peterman, VI1
Fujita, M1
Yonetomi, Y1
Takeda, H1
Nakagawa, N1
Kawabata, K1
Ohno, H1

Reviews

1 review available for indomethacin and Rhinitis, Allergic, Nonseasonal

ArticleYear
Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis.
    Journal of medicinal chemistry, 2012, Apr-12, Volume: 55, Issue:7

    Topics: Acetates; Animals; Asthma; Aza Compounds; Carbazoles; Clinical Trials as Topic; Humans; Indoleacetic

2012

Other Studies

4 other studies available for indomethacin and Rhinitis, Allergic, Nonseasonal

ArticleYear
Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis.
    Journal of pharmacological sciences, 2007, Volume: 105, Issue:3

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Diclofen

2007
Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration.
    The Journal of allergy and clinical immunology, 1983, Volume: 71, Issue:6

    Topics: Adult; Aged; Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Indometha

1983
Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma.
    The American review of respiratory disease, 1981, Volume: 123, Issue:6

    Topics: Adult; Airway Resistance; Arachidonic Acids; Asthma; Dose-Response Relationship, Drug; Female; Human

1981
Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.
    Japanese journal of pharmacology, 1997, Volume: 75, Issue:4

    Topics: Airway Resistance; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chromones; Cyclooxygenase I

1997