indomethacin has been researched along with Rhinitis, Allergic, Nonseasonal in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis." | 7.66 | Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981) |
| "To examine the role of arachidonic acid metabolism in the modulation of immediate-type immunologic airway responses, we compared the effects of indomethacin (50 mg every 6 h for 96 h) and placebo on responses to antigen inhalation challenge in allergic asthmatic subjects and a group of nonasthmatic subjects with allergic rhinitis." | 3.66 | Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma. ( Adkinson, NF; Ankin, MG; Fish, JE; Peterman, VI, 1981) |
| "However, indomethacin-induced nasal blockage was not provoked in non-sensitized animals." | 1.34 | Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis. ( Fujii, M; Han, HY; Kohno, S; Mizutani, N; Nabe, T; Takenaka, H; Terada, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pettipher, R | 1 |
| Whittaker, M | 1 |
| Han, HY | 1 |
| Nabe, T | 1 |
| Mizutani, N | 1 |
| Fujii, M | 1 |
| Terada, T | 1 |
| Takenaka, H | 1 |
| Kohno, S | 1 |
| Lumry, WR | 1 |
| Curd, JG | 1 |
| Zeiger, RS | 1 |
| Pleskow, WW | 1 |
| Stevenson, DD | 1 |
| Fish, JE | 1 |
| Ankin, MG | 1 |
| Adkinson, NF | 1 |
| Peterman, VI | 1 |
| Fujita, M | 1 |
| Yonetomi, Y | 1 |
| Takeda, H | 1 |
| Nakagawa, N | 1 |
| Kawabata, K | 1 |
| Ohno, H | 1 |
1 review available for indomethacin and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Update on the development of antagonists of chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2). From lead optimization to clinical proof-of-concept in asthma and allergic rhinitis.
Topics: Acetates; Animals; Asthma; Aza Compounds; Carbazoles; Clinical Trials as Topic; Humans; Indoleacetic | 2012 |
4 other studies available for indomethacin and Rhinitis, Allergic, Nonseasonal
| Article | Year |
|---|---|
Nasal blockage induced by oral administration of non-steroidal anti-inflammatory drugs in a guinea-pig model of allergic rhinitis.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Chromones; Diclofen | 2007 |
Aspirin-sensitive rhinosinusitis: the clinical syndrome and effects of aspirin administration.
Topics: Adult; Aged; Aspirin; Desensitization, Immunologic; Drug Hypersensitivity; Female; Humans; Indometha | 1983 |
Indomethacin modification of immediate-type immunologic airway responses in allergic asthmatic and non-asthmatic subjects: evidence for altered arachidonic acid metabolism in asthma.
Topics: Adult; Airway Resistance; Arachidonic Acids; Asthma; Dose-Response Relationship, Drug; Female; Human | 1981 |
Effects of a specific cysteinyl leukotriene antagonist, pranlukast, on antigen-induced cysteinyl leukotriene-mediated rhinitis in guinea pigs.
Topics: Airway Resistance; Animals; Anti-Allergic Agents; Anti-Asthmatic Agents; Chromones; Cyclooxygenase I | 1997 |