indomethacin has been researched along with Retinal Diseases in 35 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Retinal Diseases: Diseases involving the RETINA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We conducted a prospective, double-masked, controlled study to determine the effects of indomethacin in preventing the development of cystoid macular edema after retinal detachment surgery." | 9.05 | Incidence of cystoid macular edema after retinal detachment surgery and the use of topical indomethacin. ( Asakura, M; Maekubo, K; Manabe, R; Miyake, K; Miyake, Y, 1983) |
| "A prospective double-masked study of 500 patients was performed to assess the effect of topical indomethacin on the angiographic incidence of cystoid macular edema (CME) in patients undergoing intraocular lens implant surgery." | 9.05 | Prophylaxis of pseudophakic cystoid macular edema with topical indomethacin. ( Jampol, LM; Kraff, MC; Lieberman, HL; Peyman, GA; Sanders, DR, 1982) |
| "A controlled, double-masked study in which patients with cystoid macular edema of more than four months' duration were treated with indomethacin failed to demonstrate a significant visual improvement when compared to patients who were treated with placebo." | 9.04 | Ineffectiveness of indomethacin in the treatment of chronic cystoid macular edema. ( Cohen, N; Katiz, I; Klein, RM; Wallyn, RH; Yannuzzi, LA, 1977) |
| "In patients treated with oral indomethacin for four weeks after intracapsular cataract extraction, five of 57 eyes (9%) had cystoid macular edema four to six weeks postoperatively as shown by fluorescein angiography." | 7.66 | The effect of indomethacin pretreatment on aphakic cystoid macular edema. ( Katzin, HM; Klein, RM; Yannuzzi, LA, 1979) |
| "Topically administered indomethacin was found to reduce the occurrence of cystoid macular edema after lens extraction." | 7.65 | Prevention of cystoid macular edema after lens extraction by topical indomethacin (I). A preliminary report. ( Miyake, K, 1977) |
| "Indomethacin is a known inhibitor of prostaglandin synthesis." | 6.65 | Indomethacin as a means of preventing cystoid macular edema following intracapsular cataract extraction. ( Frank, KE; Reinhart, WJ; Sholiton, DB, 1979) |
| "We conducted a prospective, double-masked, controlled study to determine the effects of indomethacin in preventing the development of cystoid macular edema after retinal detachment surgery." | 5.05 | Incidence of cystoid macular edema after retinal detachment surgery and the use of topical indomethacin. ( Asakura, M; Maekubo, K; Manabe, R; Miyake, K; Miyake, Y, 1983) |
| "A prospective double-masked study of 500 patients was performed to assess the effect of topical indomethacin on the angiographic incidence of cystoid macular edema (CME) in patients undergoing intraocular lens implant surgery." | 5.05 | Prophylaxis of pseudophakic cystoid macular edema with topical indomethacin. ( Jampol, LM; Kraff, MC; Lieberman, HL; Peyman, GA; Sanders, DR, 1982) |
| "A controlled, double-masked study in which patients with cystoid macular edema of more than four months' duration were treated with indomethacin failed to demonstrate a significant visual improvement when compared to patients who were treated with placebo." | 5.04 | Ineffectiveness of indomethacin in the treatment of chronic cystoid macular edema. ( Cohen, N; Katiz, I; Klein, RM; Wallyn, RH; Yannuzzi, LA, 1977) |
| " These factors (immaturity, hyperoxia, hypoxia, blood transfusions, intraventricular hemorrhage, apnea, infection, hypercarbia, hypocarbia, patent ductus arteriosus, prostaglandin synthetase inhibitors, vitamin E deficiency, lactic acidosis, prenatal complications, genetic factors) may all be present in an infant." | 4.76 | A reexamination of the role of oxygen in retrolental fibroplasia. ( Dangman, B; Lucey, JF, 1984) |
| "In patients treated with oral indomethacin for four weeks after intracapsular cataract extraction, five of 57 eyes (9%) had cystoid macular edema four to six weeks postoperatively as shown by fluorescein angiography." | 3.66 | The effect of indomethacin pretreatment on aphakic cystoid macular edema. ( Katzin, HM; Klein, RM; Yannuzzi, LA, 1979) |
| "Topically administered indomethacin was found to reduce the occurrence of cystoid macular edema after lens extraction." | 3.65 | Prevention of cystoid macular edema after lens extraction by topical indomethacin (I). A preliminary report. ( Miyake, K, 1977) |
| "Indomethacin is a known inhibitor of prostaglandin synthesis." | 2.65 | Indomethacin as a means of preventing cystoid macular edema following intracapsular cataract extraction. ( Frank, KE; Reinhart, WJ; Sholiton, DB, 1979) |
| "We describe a 9 1/2-year-old boy with Bartter's syndrome and severe retinopathy whose features may be those of a previously unrecognized disorder." | 1.29 | Bartter's syndrome associated with severe retinopathy and presenting as pseudohypoaldosteronism in a newborn. ( Dillon, MJ; Eckhardt, S; Grant, DB, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (82.86) | 18.7374 |
| 1990's | 4 (11.43) | 18.2507 |
| 2000's | 1 (2.86) | 29.6817 |
| 2010's | 1 (2.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Russo, A | 1 |
| Morescalchi, F | 1 |
| Vezzoli, S | 1 |
| Bernini, M | 1 |
| Turano, R | 1 |
| Costagliola, C | 1 |
| De Ferrari, F | 1 |
| Semeraro, F | 1 |
| Toler, SM | 1 |
| Miyake, K | 6 |
| Miyake, Y | 1 |
| Maekubo, K | 1 |
| Asakura, M | 1 |
| Manabe, R | 1 |
| Lucey, JF | 1 |
| Dangman, B | 1 |
| Kraff, MC | 1 |
| Sanders, DR | 1 |
| Jampol, LM | 2 |
| Peyman, GA | 1 |
| Lieberman, HL | 1 |
| Fechner, PU | 1 |
| Merritt, TA | 1 |
| White, CL | 1 |
| Coen, RW | 1 |
| Friedman, WF | 1 |
| Gluck, L | 1 |
| Rosenberg, M | 1 |
| Beale, JP | 1 |
| Worst, JG | 1 |
| Severin, SL | 1 |
| Procianoy, RS | 1 |
| Garcia-Prats, JA | 1 |
| Hittner, HM | 1 |
| Adams, JM | 1 |
| Rudolph, AJ | 1 |
| Sakamura, S | 1 |
| Miura, H | 1 |
| Gomolin, JE | 1 |
| Koenekoop, RK | 1 |
| Kaliska, G | 1 |
| Kałuzny, J | 1 |
| Szweda, E | 1 |
| Mierzejewski, A | 1 |
| Eckhardt, S | 1 |
| Dillon, MJ | 1 |
| Grant, DB | 1 |
| Jaeger, W | 1 |
| Sugiyama, S | 1 |
| Norimatsu, I | 1 |
| Ozawa, T | 1 |
| Yannuzzi, LA | 2 |
| Klein, RM | 2 |
| Wallyn, RH | 1 |
| Cohen, N | 1 |
| Katiz, I | 1 |
| Tillmann, W | 1 |
| Keitel, L | 1 |
| Katzin, HM | 1 |
| Waitzman, MB | 1 |
| Sholiton, DB | 1 |
| Reinhart, WJ | 1 |
| Frank, KE | 1 |
| François, J | 1 |
| Freedman, B | 1 |
| Glass, KC | 1 |
| Shirasawa, E | 1 |
| Hikita, M | 1 |
| Larricart, P | 1 |
| Graham, CM | 1 |
| Blach, RK | 1 |
| Henkind, P | 1 |
| Gold, DH | 1 |
| Henkes, HE | 2 |
| van Lith, GH | 1 |
| Canta, LR | 1 |
| Koliopoulos, J | 2 |
| Palimeris, G | 2 |
| Velissaropoulos, P | 1 |
| Deutman, AF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Masked Comparison of Topical Ketorolac 0,4% Versus Placebo in Cataract Surgery.[NCT01542190] | Phase 4 | 80 participants (Anticipated) | Interventional | 2011-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for indomethacin and Retinal Diseases
| Article | Year |
|---|---|
Oxidative stress plays an important role in the pathogenesis of drug-induced retinopathy.
Topics: Animals; Blindness; Chloroquine; Humans; Indomethacin; Oxidative Stress; Retina; Retinal Diseases; T | 2004 |
A reexamination of the role of oxygen in retrolental fibroplasia.
Topics: Anencephaly; Apnea; Carbon Dioxide; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Exchange Transfu | 1984 |
Indomethacin retinopathy: case report and review.
Topics: Adult; Humans; Indomethacin; Male; Retinal Diseases | 1988 |
Ocular manifestations of rheumatic disorders. Natural and iatrogenic.
Topics: Adrenal Cortex Hormones; Arteritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Chloroquine; Conjunc | 1973 |
7 trials available for indomethacin and Retinal Diseases
| Article | Year |
|---|---|
REDUCTION OF VITREOUS PROSTAGLANDIN E2 LEVELS AFTER TOPICAL ADMINISTRATION OF INDOMETHACIN 0.5%, BROMFENAC 0.09%, AND NEPAFENAC 0.1.
Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Benzeneac | 2016 |
Incidence of cystoid macular edema after retinal detachment surgery and the use of topical indomethacin.
Topics: Administration, Topical; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Indom | 1983 |
Prophylaxis of pseudophakic cystoid macular edema with topical indomethacin.
Topics: Adrenal Cortex Hormones; Adult; Aged; Cataract Extraction; Clinical Trials as Topic; Double-Blind Me | 1982 |
Long-term follow-up study on prevention of aphakic cystoid macular oedema by topical indomethacin.
Topics: Administration, Topical; Aged; Aphakia, Postcataract; Double-Blind Method; Edema; Female; Follow-Up | 1980 |
Presumed photic retinopathy after cataract surgery: an angiographic study.
Topics: Cataract Extraction; Fluorescein Angiography; Flurbiprofen; Follow-Up Studies; Fundus Oculi; Humans; | 1993 |
Ineffectiveness of indomethacin in the treatment of chronic cystoid macular edema.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Edema; Female; Humans; Indomet | 1977 |
Indomethacin as a means of preventing cystoid macular edema following intracapsular cataract extraction.
Topics: Aged; Cataract Extraction; Edema; Evaluation Studies as Topic; Humans; Indomethacin; Macula Lutea; M | 1979 |
24 other studies available for indomethacin and Retinal Diseases
| Article | Year |
|---|---|
[Prevention of cystoid macula edema using indomethacin eyedrops].
Topics: Cataract Extraction; Edema; Humans; Indomethacin; Lenses, Intraocular; Macula Lutea; Ophthalmic Solu | 1982 |
Preschool assessment of infants with a patent ductus arteriosus: comparison of ligation and indomethacin therapy.
Topics: Body Height; Body Weight; Bronchopulmonary Dysplasia; Child Development; Child, Preschool; Ductus Ar | 1982 |
Pharmacologic therapy of aphakic cystoid macular edema. A review.
Topics: Administration, Topical; Adrenal Cortex Hormones; Edema; Humans; Indomethacin; Macula Lutea; Prostag | 1982 |
Indomethacin and CME.
Topics: Aged; Cataract Extraction; Edema; Female; Gastrointestinal Diseases; Humans; Indomethacin; Macula Lu | 1980 |
Indomethacin and CME.
Topics: Cataract Extraction; Edema; Humans; Indomethacin; Macula Lutea; Ophthalmic Solutions; Postoperative | 1980 |
Late cystoid macular edema in pseudophakia.
Topics: Adrenal Cortex Hormones; Aged; Betamethasone; Cataract Extraction; Edema; Female; Humans; Indomethac | 1980 |
Use of indomethacin and its relationship to retinopathy of prematurity in very low birthweight infants.
Topics: Ductus Arteriosus, Patent; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Infant, | 1980 |
[Use of transconjunctival cryoapplication in chronic pars planitis with involvement of peripheral retina and choroid].
Topics: Adolescent; Adult; Choroid Diseases; Cryosurgery; Dexamethasone; Female; Humans; Indomethacin; Male; | 1993 |
Bartter's syndrome associated with severe retinopathy and presenting as pseudohypoaldosteronism in a newborn.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Child; Humans; Indomethacin; Male; Pseudo | 1995 |
[Acquired colour-vision-deficiencies caused by side-effects of pharmacotherapy (author's transl)].
Topics: Antipsychotic Agents; Chloramphenicol; Chloroquine; Chlorpropamide; Color Vision Defects; Contracept | 1977 |
Prevention of cystoid macular edema after lens extraction by topical indomethacin (I). A preliminary report.
Topics: Administration, Topical; Aged; Cataract Extraction; Edema; Humans; Indomethacin; Lens, Crystalline; | 1977 |
Prevention of cystoid macular edema after lens extraction by topical indomethacin (III) radioimmunoassay measurement of prostaglandins in the aqueous during and after lens extraction procedures.
Topics: Aged; Aqueous Humor; Cataract Extraction; Edema; Female; Humans; Indomethacin; Macula Lutea; Male; M | 1978 |
[Indomethacin induced corneal deposits (author's transl)].
Topics: Aged; Arthritis, Rheumatoid; Cornea; Eye Diseases; Female; Humans; Indomethacin; Lacrimal Duct Obstr | 1977 |
The effect of indomethacin pretreatment on aphakic cystoid macular edema.
Topics: Adult; Aged; Aphakia, Postcataract; Edema; Humans; Indomethacin; Macula Lutea; Middle Aged; Retinal | 1979 |
Topical indomethacin in treatment and prevention of intraocular inflammation--with special reference to lens extraction and cystoid macular edema.
Topics: Animals; Edema; Humans; Indomethacin; Inflammation; Intraocular Pressure; Lenses, Intraocular; Macul | 1979 |
[Toxic retinopathies].
Topics: Chloroquine; Copper; Digitalis Glycosides; Epinephrine; Ethambutol; Humans; Immunosuppressive Agents | 1979 |
Prophylaxis of aphakic cystoid macular edema using topical indomethacin.
Topics: Administration, Topical; Aged; Aphakia, Postcataract; Edema; Fluorescein Angiography; Follow-Up Stud | 1978 |
Weiss v. Solomon: a case study in institutional responsibility for clinical research.
Topics: Cataract Extraction; Compensation and Redress; Disclosure; Ethics Committees, Research; Fluorescein | 1990 |
Hypotheses on the role of prostaglandins in the pathogenesis of epinephrine maculopathy and aphakic cystoid macular edema.
Topics: Animals; Aqueous Humor; Blood-Retinal Barrier; Epinephrine; Humans; Indomethacin; Macula Lutea; Macu | 1989 |
[Retinal diseases].
Topics: Anti-Bacterial Agents; Antimalarials; Antineoplastic Agents; Antipsychotic Agents; Canthaxanthin; Ca | 1985 |
Indomethacin retinopathy.
Topics: Arthritis, Rheumatoid; Color Perception; Dark Adaptation; Electroretinography; Fluoresceins; Fundus | 1972 |
On acquired colour vision disturbances during treatment with ethambutol and indomethacin.
Topics: Adolescent; Adult; Aged; Child; Color Vision Defects; Ethambutol; Female; Humans; Indomethacin; Macu | 1972 |
Electrophysiological findings in patients treated with indomethacin.
Topics: Adaptation, Ocular; Adult; Age Factors; Aged; Electroretinography; Female; Humans; Indomethacin; Mal | 1972 |
Electrodiagnostic procedures in drug-induced ocular diseases.
Topics: Chloroquine; Electrodiagnosis; Electrooculography; Electroretinography; Evoked Potentials; Eye; Huma | 1973 |