Page last updated: 2024-10-29

indomethacin and Pyrexia

indomethacin has been researched along with Pyrexia in 228 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
"Substance P (SP) is involved in fever that is induced by lipopolysaccharide (LPS) but not by interleukin-1β or macrophage inflammatory protein-1α."7.83Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever. ( Barbosa, FL; Borges, BS; Brito, HO; Fraga, D; Franco, CRC; Reis, RCD; Zampronio, AR, 2016)
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively."7.80Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014)
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)."7.73The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005)
"Intraperitoneal indomethacin at 10 mg kg(-1) attenuated both phases of intravenous LPS (2 microg kg(-1)) fever, but the first more so than the second; at 50 mg kg(-1), it inhibited the febrile response completely."7.71Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs. ( Blatteis, CM; Li, S; Llanos-Q, J; Steiner, AA, 2001)
"A 77-year-old man with relapsed non-Hodgkin's lymphoma, diffuse large B-cell type, was treated with naproxen, a nonsteroidal anti-inflammatory drug (NSAID), for paraneoplastic fever."7.71Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma. ( Iwabe, K; Kobayashi, S; Masuda, M; Mizoguchi, H; Motoji, T; Teramura, M; Yoshinaga, K, 2001)
"We have studied the mechanism by which interleukin-8 (IL-8) induces fever in rats."7.69Interleukin-8 induces fever by a prostaglandin-independent mechanism. ( Cunha, FQ; Ferreira, SH; Silva, CA; Souza, GE; Zampronio, AR, 1994)
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin."7.69[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995)
" This case report and review concerns a patient with Sweet's syndrome in whom dramatic relief of severe arthralgias, myalgias, and painful skin lesions occurred using indomethacin."7.65Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin. ( Hoffman, GS, 1977)
"Fever is frequently a symptom in patients suffering from cancer and in most cases it is related to infections or complications of the treatment."6.67[Antipyretic effect of indomethacin vs aspirin in fever of tumor origin]. ( Asef, SG; Berbotto, GA; Elias, G; Ostoich, MT; Teglia, O, 1993)
"Substance P (SP) is involved in fever that is induced by lipopolysaccharide (LPS) but not by interleukin-1β or macrophage inflammatory protein-1α."3.83Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever. ( Barbosa, FL; Borges, BS; Brito, HO; Fraga, D; Franco, CRC; Reis, RCD; Zampronio, AR, 2016)
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively."3.80Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014)
" The oral administration of the Chantaleela recipe reduced ulcer formation in acute gastric ulcer models (EtOH/HCl-, indomethacin-, and stress-induced gastric lesions)."3.78Anti-inflammatory and anti-ulcerogenic activities of Chantaleela recipe. ( Jaijoy, K; Khonsung, P; Nanna, U; Piyabhan, P; Sireeratawong, S; Soonthornchareonnon, N, 2012)
"This study compared the antipyretic effects of ibuprofen and indomethacin regarding the efficacy in blocking fevers induced by lipopolysaccharide (LPS from E."3.77Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin V₁ receptors. ( Cristofoletti, R; Fabricio, AS; Lindsey, CJ; Melo, MC; Soares, DM; Souza, GE; Veiga-Souza, FH, 2011)
"Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)-dependent and the other, PG-independent and involving endothelin-1 (ET-1)."3.77The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus. ( de Souza, GE; Fabrício, AS; Figueiredo, MJ; Kanashiro, A; Machado, RR; Malvar, Ddo C; Rae, GA; Soares, DM, 2011)
" The anti- oedema effect was compared with indomethacin."3.76Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum. ( Antonisamy, P; Ignacimuthu, S, 2010)
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)."3.73The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005)
" This study was undertaken to elucidate the effects of the COX-inhibitor Indomethacin (INDO) and the selective FLAP inhibitor MK-886 on LPS-induced hypothermia, mortality and increase in production of hypothalamic prostaglandin E(2) (PGE(2)) and leukotriene during endotoxemia."3.72Involvement of eicosanoids in the hypothermic response to lipopolysaccharide during endotoxemia in rats. ( Azab, AN; Kaplanski, J, 2004)
"Intraperitoneal indomethacin at 10 mg kg(-1) attenuated both phases of intravenous LPS (2 microg kg(-1)) fever, but the first more so than the second; at 50 mg kg(-1), it inhibited the febrile response completely."3.71Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs. ( Blatteis, CM; Li, S; Llanos-Q, J; Steiner, AA, 2001)
"A 77-year-old man with relapsed non-Hodgkin's lymphoma, diffuse large B-cell type, was treated with naproxen, a nonsteroidal anti-inflammatory drug (NSAID), for paraneoplastic fever."3.71Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma. ( Iwabe, K; Kobayashi, S; Masuda, M; Mizoguchi, H; Motoji, T; Teramura, M; Yoshinaga, K, 2001)
"A novel pre-formed pyrogenic factor (PFPF), released by LPS-stimulated macrophages, has been identified, that induces an indomethacin-resistant fever."3.70Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages. ( de Souza, GE; Hoadley, ME; Hopkins, SJ; Luheshi, G; Rothwell, NJ; Zampronio, AR, 2000)
"Recently, the carbon monoxide (CO)-heme oxygenase pathway has been shown to play an important role in fever generation by acting on the central nervous system, but the mechanisms involved have not been assessed."3.70Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way. ( Branco, LG; Steiner, AA, 2000)
" induced by acetic acid and the fever elicited by baker's yeast."3.70Antiinflammatory potency of dehydrocurdione, a zedoary-derived sesquiterpene. ( Endo, M; Fujii, E; Hohsho, H; Muraki, T; Shiba, N; Shibuya, H; Tokunaga, Y; Wada, K; Yoshioka, T, 1998)
" Intraperitoneal pretreatment with the cyclo-oxygenase inhibitor indomethacin (2 mg kg(-1)), which partially reduced LPS-induced fever, did not modify the hyperthermic response to endothelin-1 (3 fmol, i."3.70Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats. ( D'Orléans-Juste, P; Fabricio, AS; Rae, GA; Silva, CA; Souza, GE, 1998)
" Indomethacin (IND) has previously been shown to prevent lipopolysaccharide (LPS) fever in prepubertal pigs."3.70Comparison of the antipyretic actions of indomethacin and L-745,337, a selective cyclooxygenase-2 inhibitor, in endotoxin-treated prepubertal pigs. ( Parrott, RF; Vellucci, SV, 1998)
"We have studied the mechanism by which interleukin-8 (IL-8) induces fever in rats."3.69Interleukin-8 induces fever by a prostaglandin-independent mechanism. ( Cunha, FQ; Ferreira, SH; Silva, CA; Souza, GE; Zampronio, AR, 1994)
"As zymosan-induced arthritis in rats combines dual activation of early prostaglandin-dependent processes (edema, fever, pain) and IL-1 related effects on cartilage metabolism, we compared the respective influences of indomethacin (IMT) and dexamethasone (DEX) on its course."3.69Zymosan-induced arthritis in rats. II. Effects of anti-inflammatory drugs. ( Gegout, P; Gillet, P; Netter, P; Terlain, B, 1995)
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin."3.69[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995)
"7 microgram/kg] induce monophasic fever, increase anterior and posterior pituitary hormone release, and enhance hypothalamic c-Fos expression in pigs, all of which can be prevented by indomethacin (Ind)."3.69Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs. ( Forsling, ML; Goode, JA; Lloyd, DM; Parrott, RF; Vellucci, SV, 1997)
" Both the fever and the increased circulating levels of IFN, TNF, and IL-2 produced by SEA were decreased by pretreatment with indomethacin (a cyclo-oxygenase inhibitor) (15 mg/kg, intraperitoneally), anisomycin (a protein synthesis inhibitor) (15 mg/kg, subcutaneously), or dexamethasone (an effective anti-inflammatory and immunosuppressive agent) (4 mg/kg, intravenously) in rabbits."3.69Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits. ( Huang, WT; Lin, MT; Won, SJ, 1997)
" In rat adjuvant arthritis, NS-398 showed a therapeutic effect comparable to that seen with loxoprofen but less than that seen with indomethacin and diclofenac."3.68NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993)
"To investigate the relation of arachidonate metabolism to the induction of fever by interleukin-1, indomethacin was administered in either an intracerebroventricular (icv) or a subcutaneous (sc) route in conscious rabbits."3.68Characterization and mechanism of fever induction by interleukin-1 beta. ( Hashimoto, M, 1991)
" In adjuvant arthritis, E5090 suppressed both the paw swelling and the enhancements of ESR and number of peripheral blood leucocytes, like the steroidal antiinflammatory drug prednisolone."3.68Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation. ( Chiba, K; Goto, M; Hashida, R; Ono, H; Shirota, H, 1991)
"These experiments sought to determine the role of arginine vasopressin (AVP) in the inability of newborns to produce a fever."3.67Vasopressin functions as an endogenous antipyretic in the newborn. ( Kasting, NW; Wilkinson, MF, 1987)
"Acetylsalicylic acid (300 mg/kg), mefenamic acid (30 mg/kg) or indomethacin (20 mg/kg) given orally in the doses preventing the postpyrogenic fever, inhibited the stimulatory effect of LPS on phagocytic and killing activity of neutrophils."3.67Inhibition of postpyrogenic increase of phagocytic and killing activity of neutrophils by nonsteroid antiinflammatory drugs. ( Debowy, J; Garbuliński, T; Obmińska-Domoradzka, B; Switała, M, 1988)
"Effects of indomethacin, a potent inhibitor of prostaglandin (PG) synthesis, on the fever induced by recombinant human interleukin 1-alpha (rhIL 1-alpha) was studied in conscious rabbits."3.67Effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits. ( Bando, T; Hashimoto, K; Hashimoto, M; Iriki, M, 1988)
"In the rabbit, intracerebroventricular administration of dibutyryl cyclic AMP (DBC) produces fever which is selectively antagonised by phenoxybenzamine."3.66Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit. ( Kandasamy, SB, 1980)
" The effects of indomethacin on fever induced by MDP or its conjugated derivative were studied."3.66Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide. ( Chedid, L; Dinarello, CA; Parant, F; Parant, M; Riveau, G; Wolff, SM, 1980)
" This case report and review concerns a patient with Sweet's syndrome in whom dramatic relief of severe arthralgias, myalgias, and painful skin lesions occurred using indomethacin."3.65Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin. ( Hoffman, GS, 1977)
" Arachidonate fever was inhibited by intraventricular injection of indomethacin, but not by the simultaneous intraventricular injection of either of the two prostaglandin antagonists SC 19220 or HR 546."3.65Effects of prostaglandin antagonism on sodium arachidonate fever in rabbits. ( Laburn, H; Mitchell, D; Rosendorff, C, 1977)
"The simlutaneous oral administration of benorylate (4-(acetamido) phenyl 2-acetoxybenzoate) with either indomethacin or phenylbutazone to rats suffering from Freund's adjuvant-induced arthritis leads to an anti-inflammatory effect which is significantly greater than the effect of the same drugs administered alone."3.65Benorylate interaction with indomethacin and phenylbutazone. ( Khalili-Varasteh, H; Legros, J; Rosner, I, 1976)
"The capacity of ibuprofen to reduce fever in children was compared with that of aspirin, paracetamol, aminophenazone and indomethacin."3.65Oral antipyretic therapy. ( Keinänen, S; Kouvalainen, K; Similä, S, 1976)
" In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin."3.65Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975)
"Evidence for the effectiveness of ketoprofen in animal models of inflammation and its antipyretic effect is reviewed."3.65Some pharmacological and toxicological studies on ketoprofen. ( Ducrot, R; Guyonnet, JC; Julou, L; Pasquet, J, 1976)
"LADG for early gastric cancer is a feasible and safe procedure with short-term clinical results superior to those of ODG."2.78Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial. ( Bax, L; Futawatari, N; Katada, N; Kikuchi, S; Okutomi, T; Sakuramoto, S; Wang, G; Watanabe, M; Yamashita, K, 2013)
"Paraneoplastic fever is well known, and is not an uncommon problem in daily practice."2.67A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever. ( Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A, 1990)
"Indomethacin was significantly quicker at clearing fever than acetaminophen (P < 0."2.67Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria. ( Looareesuwan, S; Wilairatana, P, 1994)
"Fever is frequently a symptom in patients suffering from cancer and in most cases it is related to infections or complications of the treatment."2.67[Antipyretic effect of indomethacin vs aspirin in fever of tumor origin]. ( Asef, SG; Berbotto, GA; Elias, G; Ostoich, MT; Teglia, O, 1993)
"Systemic-onset juvenile idiopathic arthritis (SoJIA), sometimes called Still's disease, is a systemic inflammatory disease classified within the spectrum of juvenile idiopathic arthritis (JIA)."2.48Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease. ( Cimaz, R; Hofer, M; Von Scheven, A, 2012)
"Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis."1.46Juvenile Idiopathic Arthritis. ( Adrovic, A; Barut, K; Kasapçopur, Ö; Şahin, S, 2017)
"Morphine-induced fever was not modified by the cyclooxygenase (COX) inhibitor indomethacin (2."1.35Endogenous opioids: role in prostaglandin-dependent and -independent fever. ( Fernandes, LC; Fraga, D; Machado, RR; Souza, GE; Zampronio, AR, 2008)
"Exposure to hypoxemia resulted in significant elevation of plasma IL-6 in both untreated and treated with lipopolysaccharide (LPS) mice."1.33Hypoxia-induced sickness behaviour. ( Kozak, W; Walentynowicz, K; Wrotek, S, 2006)
"Pre-treatment with indomethacin reduced the fever and adrenocortical activation induced by gp120 administration, but not its behavioral effects."1.31Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandins. ( Barak, O; Ben-Hur, T; Goshen, I; Taylor, AN; Weidenfeld, J; Yirmiya, R, 2002)
"Fever was monitored using a rectal probe."1.31Involvement of CRH in fever induced by a distinct pre-formed pyrogenic factor (PFPF). ( Hopkins, SJ; Melo, MC; Souza, GE; Zampronio, AR, 2000)
"Indomethacin was a potent inhibitor of both COX-1 (IC50 = 18 +/- 3 nM) and COX-2 (IC50 = 26 +/- 6 nM) under the same assay conditions."1.30Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. ( Boyce, S; Brideau, C; Chan, CC; Charleson, S; Cromlish, W; Ethier, D; Evans, J; Falgueyret, JP; Ford-Hutchinson, AW; Gordon, R; Greig, G; Gresser, M; Guay, J; Kargman, S; Léger, S; Mancini, JA; O'Neill, G; Ouellet, M; Percival, MD; Riendeau, D; Rodger, IW; Thérien, M; Wang, Z; Webb, JK; Wong, E, 1997)
"Local inflammation was induced by subcutaneous injection of turpentine (100 microl/mouse)."1.30Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation. ( Conn, CA; Kluger, MJ; Kozak, W; Rudolph, K; Soszynski, D, 1997)
"A patient with rheumatoid arthritis is described who presented with low-grade fever for 3 months, in whom Actinobacillus ureae was cultured from bone marrow aspirate."1.30Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient. ( Avlami, A; Dounis, E; Kordossis, T; Papalambrou, C; Tzivra, M, 1997)
"Fever was induced by intraperitoneal injection of lipopolysaccharide at doses from 10 micrograms/kg to 2."1.30Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice. ( Archuleta, I; Kluger, MJ; Kozak, A; Kozak, W; Mayfield, KP; Rudolph, K, 1998)
"Indomethacin treatment (5 mg/kg subcutaneously) completely abolished these responses."1.30Polysaccharide mannan components of Candida albicans and Saccharomyces cerevisiae cell wall produce fever by intracerebroventricular injection in rats. ( Akarsu, ES; Ataoğlu, H; Ataoğlu, O; Doğan, MD, 1999)
"The influence of dosing time on the fever induced by interferon-alpha (IFN-alpha) was investigated in ICR male mice under light-dark cycle."1.30Circadian rhythm of fever induced by interferon-alpha in mice. ( Higuchi, S; Koyanagi, S; Ohdo, S; Yukawa, E, 1997)
"Pretreatment with indomethacin, an inhibitor of prostaglandin synthesis, did not affect IL-1 beta production in the brain induced by 4 micrograms kg-1 LPS."1.29Interleukin-1 beta production in the rabbit brain during endotoxin-induced fever. ( Morimoto, A; Murakami, N; Nakamori, T; Watanabe, T; Yamaguchi, K, 1994)
"Prolonged fever is an uncommon diagnostic problem in a spinal cord injury patient."1.29Prolonged fever and heterotopic ossification in a C4 tetraplegic patient. Case report. ( Kong, KH; Tow, AP, 1995)
"LPS induced thermal and mechanical hyperalgesia which was reversed by i."1.29Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists. ( Dray, A; Perkins, M; Walker, K, 1996)
"1."1.29Nitric oxide synthase-cyclo-oxygenase pathways in organum vasculosum laminae terminalis: possible role in pyrogenic fever in rabbits. ( Lin, JH; Lin, MT, 1996)
"The indomethacin was well tolerated."1.29A retrospective analysis of the effect of indomethacin on adverse reactions to orthoclone OKT3 in the therapy of acute renal allograft rejection. ( Burke, JF; Dunn, SR; Francos, BB; Francos, GC; Gaughan, WJ, 1994)
" MIP-1 induced a biphasic or monophasic fever of short latency characterized by an inverse dose-response curve."1.28Macrophage inflammatory protein-1: unique action on the hypothalamus to evoke fever. ( Cerami, A; Davatelis, G; Fahey, T; Miñano, FJ; Myers, RD; Paez, X; Sancibrian, M; Sherry, B; Vizcaino, M, 1990)
"Fever was induced by intravenous injection of lipopolysaccharide (LPS) of E."1.28Influence of nonsteroid anti-inflammatory drugs on lymphocyte subpopulation and on the primary humoral response in normothermic and feverish rabbits. ( Debowy, J; Garbuliński, T; Obmińska-Domoradzka, B; Switała, M, 1989)
" After acclimation, rectal temperatures were recorded hourly following five separate ascorbate dosage treatments: 0 (control dosage), 2, 10 or 50 mg ascorbic acid/100 g body wt, or 50 mg ascorbic acid and 0."1.28Effect of single oral doses of ascorbic acid on body temperature in healthy guinea pigs. ( Johnston, CS, 1989)
"Fevers were induced by IP EP (1."1.27Activation of acute-phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs. ( Ahokas, RA; Blatteis, CM; Hunter, WS; Llanos, J; Mashburn, TA, 1984)
"Indomethacin pretreatment prevented the initial phase of pulmonary hypertension, the increases in thromboxane and prostacyclin metabolites in lung lymph, and the febrile response to toxin infusion but did not modify the granulocytopenia or the increased pulmonary vascular permeability."1.27Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. ( Brigham, KL; Larsson, LE; Ogletree, ML; Rojas, J; Stahlman, MT, 1983)
"Indomethacin was effective in reducing temperature in 10 of 11 cases which showed a dipyrone-resistant hyperthermia developing in the first 24 hours after brain damage, while no significant antipyretic effect was seen in hyperthermic cases developing more than 72 hours after cranial trauma or brain surgery."1.27Indomethacin is effective against neurogenic hyperthermia following cranial trauma or brain surgery. ( Benedek, G; Colner-Sasi, K; Hortobágyi, A; Janáky, J; Obál, F; Tóth-Daru, P, 1987)
"Treatment with indomethacin prevented the 1-2 degrees C increase in body temperature observed in septic animals."1.27Fever is not responsible for the elevated glucose kinetics in sepsis. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987)
"indomethacin were qualitatively similar to i."1.27The antipyretic effects of centrally administered vasopressin at different ambient temperatures. ( Kasting, NW; Wilkinson, MF, 1987)
"Biphasic fevers were induced in sheep with intravascular infusions or injections of 4-10 mug (80-200 ng/kg) of endotoxin, whereas monophasic fevers were obtained with doses of 1-2/mug (20-40 ng/kg)."1.26Role of prostaglandin E in the biphasic fever response to endotoxin. ( Brown, SK; Hull, SS; McCracken, JA; Skarnes, RC, 1981)
"Indomethacin pretreatment prevented the first part of the febrile response and only a slight temperature rise occurred after a long latency."1.26Endotoxin fever in the newborn kitten. The role of prostaglandins and monoamines. ( Székely, M, 1979)
" The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid."1.25Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975)
" A dose of 10 mug/kg caused a parallel shift to the right of the log dose-response curve for I."1.25The antipyretic effect of indomethacin. ( Clark, WG; Cumby, HR, 1975)
"Indomethacin was more potent than paracetamol and both were more potent than injected I."1.25Prostaglandins, endotoxin and lipid A on body temperature in rats. ( Feldberg, W; Saxena, PN, 1975)
"Fever was produced by injection of the bacterial pyrogen of Shigella dysenteriae either into the third ventricle, cisterna magna or I."1.25Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats. ( Feldberg, W; Gupta, KP; Milton, AS; Wendlandt, S, 1973)

Research

Studies (228)

TimeframeStudies, this research(%)All Research%
pre-1990106 (46.49)18.7374
1990's73 (32.02)18.2507
2000's25 (10.96)29.6817
2010's21 (9.21)24.3611
2020's3 (1.32)2.80

Authors

AuthorsStudies
Terada, A1
Naruto, S1
Wachi, K1
Tanaka, S1
Iizuka, Y2
Misaka, E1
Puig, C1
Crespo, MI1
Godessart, N1
Feixas, J1
Ibarzo, J1
Jiménez, JM1
Soca, L1
Cardelús, I1
Heredia, A1
Miralpeix, M1
Puig, J1
Beleta, J1
Huerta, JM1
López, M1
Segarra, V1
Ryder, H1
Palacios, JM1
Uramaru, N1
Shigematsu, H1
Toda, A1
Eyanagi, R1
Kitamura, S1
Ohta, S1
Nascimento, WM1
Oliveira, JRS1
Cunha, RX1
Gambôa, DSR1
Silva, APS1
Lima, VLM1
Mota, CMD1
Madden, CJ1
Siddique, S1
Ahmad, KR1
Nawaz, SK1
Ahmad, SN1
Ali, R1
Inayat, I1
Suleman, S1
Kanwal, MA1
Usman, M1
Barut, K1
Adrovic, A1
Şahin, S1
Kasapçopur, Ö1
Bastos-Pereira, AL2
Fraga, D4
Dreifuss, AA1
Zampronio, AR10
Sireeratawong, S1
Khonsung, P1
Piyabhan, P1
Nanna, U1
Soonthornchareonnon, N1
Jaijoy, K1
Malvar, Ddo C2
Aguiar, FA1
Vaz, Ade L1
Assis, DC1
de Melo, MC1
Jabor, VA1
Kalapothakis, E1
Ferreira, SH4
Clososki, GC1
de Souza, GE3
Raju, GS1
Moghal, MM1
Hossain, MS1
Hassan, MM1
Billah, MM1
Ahamed, SK1
Rana, SM1
Leite, MC1
Sugita, R1
Kubota, K1
Sugimoto, K1
Tachida, Y1
Shibayama, T1
Kiho, T1
Kawakami, K1
Shimada, K1
Brito, HO2
Barbosa, FL1
Reis, RCD1
Borges, BS1
Franco, CRC1
Xia, L1
Bartlett, D1
Leiter, JC1
Radulski, DR1
Wilhelms, DB1
Stojakovic, A1
Brito, LM1
Engblom, D1
Franco, CR1
Antonisamy, P1
Ignacimuthu, S1
Pozharitskaya, ON1
Shikov, AN1
Makarova, MN1
Kosman, VM1
Faustova, NM1
Tesakova, SV1
Makarov, VG1
Galambosi, B1
Vilela, FC1
Bitencourt, AD1
Cabral, LD1
Franqui, LS1
Soncini, R1
Giusti-Paiva, A1
Soares, DM3
Cristofoletti, R2
Melo, MC2
Lindsey, CJ1
Veiga-Souza, FH1
Fabricio, AS5
Souza, GE8
Kanashiro, A1
Machado, RR2
Figueiredo, MJ1
Rae, GA2
Osborn, O1
Sanchez-Alavez, M1
Dubins, JS1
Gonzalez, AS1
Morrison, B1
Hadcock, JR1
Bartfai, T1
Smith, FG1
Fewell, JE1
Qi, W1
Cimaz, R1
Von Scheven, A1
Hofer, M1
Sakuramoto, S1
Yamashita, K1
Kikuchi, S1
Futawatari, N1
Katada, N1
Watanabe, M2
Okutomi, T1
Wang, G1
Bax, L1
Adham, KG1
Al-Humaidhi, EM1
Daghestani, MH1
Aleisa, NA1
Farhood, MH1
Bicego, KC1
Steiner, AA3
Antunes-Rodrigues, J1
Branco, LG2
Stone, JH1
Barak, O1
Weidenfeld, J1
Goshen, I1
Ben-Hur, T1
Taylor, AN1
Yirmiya, R1
Guerrero-Lindner, E1
Castro, M1
Muñoz, JM1
Arruebo, MP1
Murillo, MD1
Buéno, L2
Plaza, MA2
BRODIE, DA1
KUNDRATS, SK1
Nomoto, S1
Azab, AN1
Kaplanski, J2
Fonseca Aizpuru, EM1
Nuño Mateo, FJ1
Noval Menéndez, J1
Menéndez Calderón, MJ1
Kagiwada, K1
Chida, D1
Sakatani, T1
Asano, M1
Nambu, A1
Kakuta, S1
Iwakura, Y1
Rau, V1
Grijalva, CV1
Veiga, FH1
Navarra, P1
Daud, A1
Habib, N1
Riera, AS1
Werner, MF1
Hiratsuka Veiga-Souza, F1
Javier Miñano, F1
Petto Souza, GE1
Kozak, W5
Wrotek, S2
Walentynowicz, K2
Szefer, M1
Wojtal, B1
Terlecki, P1
Sam, TS1
Ngan, MP1
Riendeau, D2
Robichaud, A1
Rudd, JA1
Fernandes, LC1
Laburn, H2
Mitchell, D3
Stephen, J1
Krupin, T1
Koloms, BA1
Klutho, L1
Webb, G1
Becker, B1
Kandasamy, SB4
Nakamura, H1
Yokoyama, Y1
Seto, Y1
Kadokawa, T1
Shimizu, M1
Tocco, RJ1
Kahn, LL1
Kluger, MJ6
Vander, AJ3
Baracos, V1
Rodemann, HP1
Dinarello, CA4
Goldberg, AL1
Rojas, J1
Larsson, LE1
Ogletree, ML1
Brigham, KL1
Stahlman, MT1
Blatteis, CM5
Hunter, WS1
Llanos, J1
Ahokas, RA1
Mashburn, TA1
Greer, KE1
Cooper, PH1
Nistico', G1
Rotiroti, D1
De Gori, N1
Pisanti, N1
Mandolfino, T1
Tommasini, R2
Kitamoto, O1
Kobayashi, H1
Kaji, M1
Kashiwagi, S1
Hayashida, K1
Shingu, T1
Hara, K1
Izumikawa, K1
Fukui, M1
Ikebe, A1
Yamaguchi, K2
Suzuyama, Y1
Horiuchi, N1
Komori, M1
Fujimori, I2
Hayakawa, Y1
Katayama, T1
Kohno, M1
Sekita, K1
Tanaka, T1
Scott, GM1
Ward, RJ1
Wright, DJ1
Robinson, JA1
Onwubalili, JK1
Gauci, CL1
Williams, BA1
Parant, M2
Riveau, G2
Chedid, L2
Martin, JP1
Perret, JL1
Pasquier, J1
Bredt, AB1
Girey, GJ1
Warshaw, AL1
Carey, RW1
Robinson, DR1
Skarnes, RC1
Brown, SK1
Hull, SS1
McCracken, JA1
Parant, F1
Wolff, SM3
Barrier, J1
Roblot, P1
Ramassamy, A1
Becq-Giraudon, B1
Sawamura, M1
Yamaguchi, S1
Murakami, H1
Kitahara, T1
Itoh, K1
Maehara, T1
Kawada, E1
Matsushima, T1
Tamura, J1
Naruse, T2
Xin, L2
Quan, N2
Lennie, TA1
Hirvonen, MD1
McCarthy, DO1
Keesey, RE1
Parrott, RF5
Vellucci, SV4
Goode, JA2
Lloyd, DM3
Forsling, ML2
Gegout, P1
Gillet, P1
Terlain, B1
Netter, P1
Sakata, Y3
Morimoto, A4
Murakami, N7
Tow, AP1
Kong, KH1
Lopez-Valpuesta, FJ1
Myers, RD3
Lorenzetti, BB1
Devissaguet, M1
Lesieur, D1
Tsouderos, Y1
Watanabe, T6
Clark, WG4
Ceriani, G1
Lipton, JM1
Wilairatana, P1
Looareesuwan, S1
Nakamori, T3
Gaughan, WJ1
Francos, BB1
Dunn, SR1
Francos, GC1
Burke, JF1
Silva, CA3
Cunha, FQ2
Berbotto, GA1
Asef, SG1
Elias, G1
Ostoich, MT1
Teglia, O1
Conn, CA2
Wilkinson, MF4
Kasting, NW4
Coelho, MM1
Pelá, IR2
Rothwell, NJ2
First, MR2
Schroeder, TJ2
Hariharan, S2
Weiskittel, P2
Futaki, N1
Yoshikawa, K1
Hamasaka, Y1
Arai, I1
Higuchi, S2
Iizuka, H1
Otomo, S1
Samii, A1
Walker, K2
Dray, A2
Perkins, M2
Lin, JH1
Lin, MT3
Ostrov, BE1
Athreya, BH1
Eichenfield, AH1
Goldsmith, DP1
Tay, YK1
Paz, RS1
Ng, SK1
Chng, HH1
Ferguson, JL1
Harris, AH1
Davis, HD1
Landauer, MR1
Fioramonti, J1
Jin, M1
Otaka, M1
Otani, S1
Okuyama, A1
Itoh, S1
Iwabuchi, A1
Sasahara, H1
Fujimori, S1
Itoh, H1
Tashima, Y1
Masamune, O1
Szelényi, Z1
Székely, M4
Balaskó, M1
Sehic, E1
Ungar, AL1
Oladehin, A1
Soszynski, D1
Rudolph, K2
Percival, MD1
Boyce, S1
Brideau, C1
Charleson, S2
Cromlish, W1
Ethier, D1
Evans, J1
Falgueyret, JP1
Ford-Hutchinson, AW1
Gordon, R2
Greig, G1
Gresser, M1
Guay, J1
Kargman, S2
Léger, S1
Mancini, JA1
O'Neill, G1
Ouellet, M2
Rodger, IW1
Thérien, M1
Wang, Z1
Webb, JK1
Wong, E2
Chan, CC1
Huang, WT1
Won, SJ2
Ohdo, S1
Koyanagi, S1
Yukawa, E1
Lau, CK1
Black, WC1
Belley, M1
Chan, C1
Denis, D1
Gauthier, JY1
Guay, D1
Hamel, P1
Leblanc, Y1
Mancini, J1
Percival, D1
Prasit, P1
Roy, P1
Skorey, K1
Tagari, P1
Vickers, P1
Laburn, HP1
Sakurada, S1
Hales, JR1
Avlami, A1
Papalambrou, C1
Tzivra, M1
Dounis, E1
Kordossis, T1
Kido, H1
Ito, A1
Kimura, K1
Kodera, N1
Doi, T1
Fraifeld, V1
Alagiakrishnan, K1
Botti, AC1
Kodali, P1
Archuleta, I1
Mayfield, KP1
Kozak, A1
D'Orléans-Juste, P1
Yoshioka, T1
Fujii, E1
Endo, M1
Wada, K1
Tokunaga, Y1
Shiba, N1
Hohsho, H1
Shibuya, H1
Muraki, T1
Furlan, RL1
Macari, M1
Malheiros, EB1
Secato, ER1
Guerreiro, JR1
Doğan, MD1
Ataoğlu, H1
Ataoğlu, O1
Akarsu, ES1
Raghavendra, V1
Agrewala, JN1
Kulkarni, SK1
Graff, GR1
Gozal, D1
Caputa, M1
Dokladny, K1
Kurowicka, B1
Hopkins, SJ2
Hoadley, ME1
Luheshi, G1
Yoshinaga, K1
Teramura, M1
Iwabe, K1
Kobayashi, S3
Masuda, M1
Motoji, T1
Mizoguchi, H1
Süleyman, H1
Demírezer, LO1
Kuruüzüm-Uz, A1
Li, S1
Llanos-Q, J1
Khalili-Varasteh, H1
Rosner, I1
Legros, J1
Rosendorff, C1
Schlievert, PM1
Bettin, KM1
Watson, DW1
Livelli, FD1
Johnson, RA1
McEnany, MT1
Sherman, E1
Newell, J1
Block, PC1
DeSanctis, RW1
Saxena, PN2
Schuurmans, D1
Vincent, JE1
Bruinvels, J1
Bonta, IL1
Rudy, TA1
Williams, JW1
Yaksh, TL1
Perlow, M1
Mannella, W1
Brodsky, I1
Sufian, S1
Matsumoto, T1
Hoffman, GS1
Similä, S2
Kouvalainen, K1
Keinänen, S1
Cumby, HR3
Julou, L1
Guyonnet, JC1
Ducrot, R1
Pasquet, J1
Vlaho, M2
Groth, W1
Gross, R1
Adams, SS1
McCullough, KF1
Nicholson, JS1
Hirschmann, W1
Eggeling, B1
Mitrenga, D1
Sieberth, HG1
Dorfman, RI1
Feldberg, W4
Niemegeers, CJ1
Lenaerts, FM1
Janssen, PA1
Takahashi, H2
Nishimura, M2
Sakamoto, M1
Ikegaki, I2
Nakanishi, T1
Yoshimura, M2
Rogers, C1
Ghanta, V1
Hsueh, CM1
Hiramoto, N1
Hiramoto, R1
Spízková, K1
Stefl, B1
Ko, YH1
Chuang, J1
Alexander, JW1
Hashimoto, M2
Coceani, F2
Bishai, I2
Lees, J1
Hynes, N1
Miñano, FJ2
Vizcaino, M2
Ransome, OJ1
Roode, H1
Bowie, MD1
van der Merwe, PL1
Naude, SP1
Utian, HL1
Beatty, DW1
Wittenberg, DF1
Farrant, PJ1
Househam, KC1
Velasco, S1
Tarlow, M1
Olsen, K1
Shay, JW1
McCracken, GH1
Nisen, PD1
Shirota, H2
Chiba, K2
Goto, M1
Hashida, R1
Ono, H2
Sancibrian, M1
Paez, X1
Davatelis, G1
Fahey, T1
Sherry, B1
Cerami, A1
Tsavaris, N1
Zinelis, A1
Karabelis, A1
Beldecos, D1
Bacojanis, C1
Milonacis, N1
Karvounis, N1
Kosmidis, P1
LeMay, LG1
Shimozato, T1
Iwata, M1
Tamura, N1
Debowy, J3
Obmińska-Domoradzka, B3
Switała, M3
Garbuliński, T3
Simpson, RK1
Fischer, DK1
Ehni, BL1
Ramanathan, M1
Sirko, S1
Daniel, PT1
Holzschuh, J1
Berg, PA1
Johnston, CS1
Benedek, G1
Tóth-Daru, P1
Janáky, J1
Hortobágyi, A1
Obál, F1
Colner-Sasi, K1
Lang, CH1
Bagby, GJ1
Blakesley, HL1
Spitzer, JJ1
Busija, DW1
Leffler, CW1
Pourcyrous, M1
Domer, FR1
Mori, K1
Sokoloff, L1
Bando, T1
Iriki, M1
Hashimoto, K1
Sosman, JA1
Kohler, PC1
Hank, JA1
Moore, KH1
Bechhofer, R1
Storer, B1
Sondel, PM1
Suga, K1
Matsusawa, M1
Cremades, A1
Garcia-Peñarrubia, P1
Garcia, F1
Sánchez Rincón, I1
Sauvaire, D1
Michel, A1
Serrano, JJ1
Richard, M1
Katayama, K1
Terato, K1
Ikuta, H1
Yamatsu, I1
O'Reilly, B1
Shope, TR1
Asoh, T1
Shirasaka, C1
Uchida, I1
Tsuji, H1
Feest, TG1
Wallis, JP1
Stitt, JT1
Bernheim, HA1
Clavel, B1
Gazeau, JN1
Kiely, JM1
Dey, PK2
Gupta, KP2
Milton, AS2
Wendlandt, S3
Orozco-Alcala, JJ1
Baum, J1
Calabro, JJ1
Katz, RM1
Maltz, BA1
Davis, NE1
Sobański, H1
Krupinńska, J1
Gryglewski, RJ1
Schiatti, P1
Selva, D1
Arrigoni-Martelli, E1
Lerner, LJ1
Diena, A1
Sardi, A1
Maffii, G1
Banerjee, AK1
Flower, RJ1
Vane, JR1
Simon, HB1
Mössner, G1
Husmann, F1
Buttinoni, A1
Cuttica, A1
Franceschini, J1
Mandelli, V1
Orsini, G1
Passerini, N1
Turba, C1
Riedel, R1
Schoetensack, W1
Lusch, CJ1
Serpick, AA1
Slater, L1
Brewer, EJ1
Sanzgiri, RR1
Samuel, MR1
Samuel, AM1
Akizuki, M1
Katsu, M1
Kimura, ET1
Young, PR1
Dodge, PW1
Sweit, LR1
Ronchi, W1
Gardelli, G1
Tanaka, K1
Marazzi-Uberti, E1
Lumachi, B1
Gaetani, M1
Coppi, G1
Bianchi, C1
Takagi, H1
Kerawalla, FC1
Rele, RV1
Mehta, KA1
Kuhn, D1
Schilling, F1
Huhnstock, K1
Koivisto, M1
Cashin, CH1
Heading, CE1
Yamamoto, H1
Saito, C1
Okamoto, T1
Awata, H1
Inukai, T1
Hirohashi, A1
Yukawa, Y1
Silberman, HR1
McGinn, TG1
Kremer, WB1
Marcolongo, R1
Boggiano, CA1

Reviews

7 reviews available for indomethacin and Pyrexia

ArticleYear
Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease.
    Swiss medical weekly, 2012, Volume: 142

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Ar

2012
Sweet's syndrome (acute febrile neutrophilic dermatosis).
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:2

    Topics: Adult; Arthritis; Clofazimine; Diagnosis, Differential; Eye Diseases; Female; Fever; Humans; Indomet

1982
The neurological basis of fever.
    Surgical neurology, 1996, Volume: 45, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Fever; Humans; Indomethacin; Prostaglandins

1996
Successful treatment of severe cytophagic histiocytic panniculitis with cyclosporine A.
    Seminars in arthritis and rheumatism, 1996, Volume: 25, Issue:6

    Topics: Adolescent; Adrenal Cortex Hormones; Biopsy; Bone Marrow; Cyclosporine; Female; Fever; Humans; Indom

1996
Brain eicosanoids and LPS fever: species and age differences.
    Progress in brain research, 1998, Volume: 115

    Topics: Age Factors; Animals; Brain Chemistry; Chickens; Cyclooxygenase Inhibitors; Eicosanoids; Fever; Hypo

1998
A critical reappraisal of juvenile rheumatoid arthritis.
    Clinical orthopaedics and related research, 1971, Volume: 74

    Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine

1971
Inhibition of prostaglandin biosynthesis.
    Biochemical pharmacology, 1974, May-15, Volume: 23, Issue:10

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cats; Cattle; Depression, Chemical; Dogs; Fa

1974

Trials

14 trials available for indomethacin and Pyrexia

ArticleYear
Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial.
    Surgical endoscopy, 2013, Volume: 27, Issue:5

    Topics: Administration, Rectal; Aged; Analgesia, Patient-Controlled; Analgesics; Carcinoma; Comorbidity; Cri

2013
[A clinical study on the effect of K-708 (acemetacin)--a double blind comparative study with ibuprofen in upper respiratory tract inflammation with fever (author's transl)].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1981, Volume: 55, Issue:9

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Femal

1981
Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria.
    Annals of tropical medicine and parasitology, 1994, Volume: 88, Issue:4

    Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Female; Fever; Humans; Indomethacin; Malaria

1994
[Antipyretic effect of indomethacin vs aspirin in fever of tumor origin].
    Medicina, 1993, Volume: 53, Issue:1

    Topics: Aspirin; Body Temperature; Female; Fever; Humans; Indomethacin; Male; Middle Aged; Neoplasms

1993
Reduction of the initial febrile response to OKT3 with indomethacin.
    Transplantation proceedings, 1993, Volume: 25, Issue:2 Suppl 1

    Topics: Acetaminophen; Adult; Creatinine; Diphenhydramine; Drug Administration Schedule; Female; Fever; Graf

1993
Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo.
    Circulation, 1978, Volume: 57, Issue:5

    Topics: Cardiac Surgical Procedures; Clinical Trials as Topic; Cross Infection; Double-Blind Method; Fever;

1978
A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
    Journal of internal medicine, 1990, Volume: 228, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Humans; Indomethacin; Male; Napr

1990
Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and addition of indomethacin.
    Journal of the National Cancer Institute, 1988, Nov-16, Volume: 80, Issue:18

    Topics: Adult; Aged; Cytotoxicity, Immunologic; Drug Administration Schedule; Female; Fever; Humans; Hypoten

1988
Effects of indomethacin on endocrine responses and nitrogen loss after surgery.
    Annals of surgery, 1987, Volume: 206, Issue:6

    Topics: Blood Glucose; Catecholamines; Female; Fever; Glucagon; Humans; Hydrocortisone; Indomethacin; Male;

1987
Treatment of juvenile rheumatoid arthritis -- a world survey.
    The Journal of rheumatology, 1974, Volume: 1, Issue:2

    Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Australia; Clinical Trials as Topic; Drug The

1974
A comparative evaluation of indomethacin, acetaminophen and placebo as antipyretic agents in children.
    Arthritis and rheumatism, 1968, Volume: 11, Issue:5

    Topics: Acetaminophen; Chemical Phenomena; Chemistry; Child; Clinical Trials as Topic; Fever; Humans; Indome

1968
A controlled clinical trial with indomethacin as an antipyretic in children.
    Journal of postgraduate medicine, 1969, Volume: 15, Issue:1

    Topics: Child; Child, Preschool; Clinical Trials as Topic; Fever; Humans; Indomethacin; Infant; Placebos; Su

1969
[Antipyretic effects of indomethacin in acute infectious diseases--a double blind test].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1971, Volume: 45, Issue:8

    Topics: Adolescent; Adult; Aged; Cholecystitis; Colitis; Female; Fever; Humans; Indomethacin; Infections; Ma

1971
Antipyretic effect of indomethacin suppositories: A double-blind study.
    Indian pediatrics, 1969, Volume: 6, Issue:6

    Topics: Analgesics; Child; Child, Preschool; Fever; Humans; Indomethacin; Infant; Infant, Newborn; Infection

1969

Other Studies

207 other studies available for indomethacin and Pyrexia

ArticleYear
Synthesis and antiinflammatory activity of [(cycloalkylmethyl)phenyl]acetic acids and related compounds.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:2

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Female; Fever; Ibuprofen; Indomethacin; Inflamma

1984
Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors.
    Journal of medicinal chemistry, 2000, Jan-27, Volume: 43, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors

2000
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics.
    Journal of medicinal chemistry, 2010, Dec-23, Volume: 53, Issue:24

    Topics: Allergens; Analgesics; Animals; Antipyretics; Body Temperature; Drug Design; Fever; Guinea Pigs; Hyp

2010
Evaluation of the treatment of fever, pain and inflammation with Indigofera suffruticosa Miller Leaves Aqueous Extract.
    Journal of ethnopharmacology, 2022, Apr-06, Volume: 287

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Fever; Indigofera; Indomethacin; Inflam

2022
Neural circuits mediating circulating interleukin-1β-evoked fever in the absence of prostaglandin E2 production.
    Brain, behavior, and immunity, 2022, Volume: 103

    Topics: Adipose Tissue, Brown; Animals; Dinoprostone; Fever; Hypothalamus; Indomethacin; Interleukin-1beta;

2022
Evaluation of the anti-inflammatory, analgesic, anti-pyretic and anti-ulcerogenic potentials of synthetic indole derivatives.
    Scientific reports, 2023, 05-27, Volume: 13, Issue:1

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics

2023
Juvenile Idiopathic Arthritis.
    Balkan medical journal, 2017, Apr-05, Volume: 34, Issue:2

    Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents;

2017
Central mediators of the zymosan-induced febrile response.
    Journal of basic and clinical physiology and pharmacology, 2017, Nov-27, Volume: 28, Issue:6

    Topics: Animals; Body Temperature; Celecoxib; Dinoprostone; Fever; Indomethacin; Infusions, Intraventricular

2017
Anti-inflammatory and anti-ulcerogenic activities of Chantaleela recipe.
    African journal of traditional, complementary, and alternative medicines : AJTCAM, 2012, Volume: 9, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antipyretics; Carrageenan; Dinopro

2012
Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever.
    British journal of pharmacology, 2014, Volume: 171, Issue:15

    Topics: Ampyrone; Animals; Antipyretics; Body Temperature; Dinoprostone; Dipyrone; Fever; Hypothalamus; Hypo

2014
Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation.
    Biological research, 2014, Oct-28, Volume: 47

    Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Aspirin; Asteraceae; Ban

2014
Central mediators involved in the febrile response induced by polyinosinic-polycytidylic acid: lack of involvement of endothelins and substance P.
    Journal of neuroimmunology, 2015, Jan-15, Volume: 278

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Body Temperature; Celecoxib; Central N

2015
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.
    Journal of pharmacological sciences, 2016, Volume: 130, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimen

2016
Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever.
    Journal of neuroimmunology, 2016, Apr-15, Volume: 293

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Corticotropin-Releasing Hormone;

2016
Interleukin-1β and interleukin-6 enhance thermal prolongation of the LCR in decerebrate piglets.
    Respiratory physiology & neurobiology, 2016, Volume: 230

    Topics: Animals; Animals, Newborn; Body Temperature; Cyclooxygenase Inhibitors; Decerebrate State; Disease M

2016
Female Sex Hormones Influence the Febrile Response Induced by Lipopolysaccharide, Cytokines and Prostaglandins but not by Interleukin-1β in Rats.
    Journal of neuroendocrinology, 2016, Volume: 28, Issue:10

    Topics: Animals; Body Temperature; Cytokines; Estrogens; Female; Fever; Gonadal Steroid Hormones; Indomethac

2016
Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:3-4

    Topics: Acetic Acid; Analgesics; Anaphylaxis; Animals; Behavior, Animal; Chromobacterium; Dose-Response Rela

2010
Anti-inflammatory activity of a HPLC-fingerprinted aqueous infusion of aerial part of Bidens tripartita L.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2010, Volume: 17, Issue:6

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Bidens; Carrageenan; Chromatography, High Pressure Li

2010
Anti-inflammatory and antipyretic effects of Sonchus oleraceus in rats.
    Journal of ethnopharmacology, 2010, Feb-17, Volume: 127, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cotton Fiber; Disease Models, Animal; Edema; Fever;

2010
Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin V₁ receptors.
    Fundamental & clinical pharmacology, 2011, Volume: 25, Issue:6

    Topics: Animals; Antipyretics; Arginine Vasopressin; Dinoprostone; Dose-Response Relationship, Drug; Fever;

2011
The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus.
    British journal of pharmacology, 2011, Volume: 162, Issue:6

    Topics: Animals; Antipyretics; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Dipyrone; Endothel

2011
Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.
    Cytokine, 2011, Volume: 53, Issue:3

    Topics: Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Chemokine

2011
Indomethacin abolishes core temperature, but not cardiovascular or renal, responses to lipopolysaccharide in conscious lambs.
    Clinical and experimental pharmacology & physiology, 2011, Volume: 38, Issue:8

    Topics: Animals; Blood Pressure; Body Temperature; Cardiovascular Agents; Cardiovascular System; Consciousne

2011
Protective role of indomethacin on lipopolysaccharide-stimulated fever induction and cerebral catecholamine biosynthesis in Wistar rat.
    Neuro endocrinology letters, 2012, Volume: 33, Issue:7

    Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain; Dop

2012
Indomethacin impairs LPS-induced behavioral fever in toads.
    Journal of applied physiology (Bethesda, Md. : 1985), 2002, Volume: 93, Issue:2

    Topics: Animals; Behavior, Animal; Body Temperature Regulation; Bufonidae; Cyclooxygenase Inhibitors; Female

2002
Polyarteritis nodosa.
    JAMA, 2002, Oct-02, Volume: 288, Issue:13

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclophosphamide; Diagnostic Errors; Fever; Glucocor

2002
Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandins.
    Brain, behavior, and immunity, 2002, Volume: 16, Issue:6

    Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cor

2002
Central tumour necrosis factor-alpha mediates the early gastrointestinal motor disturbances induced by lipopolysaccharide in sheep.
    Neurogastroenterology and motility, 2003, Volume: 15, Issue:3

    Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Female; Fever; Gastrointestinal Motility; Huma

2003
THE EFFECT OF PYREXIA ON RAT GASTRIC SECRETION.
    Gastroenterology, 1964, Volume: 47

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Body Temperature; Fever; Gastric Juice; Hot Temp

1964
Role of prostaglandin E2 and indomethacin in the febrile response of pigeons.
    The Japanese journal of physiology, 2003, Volume: 53, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Columbidae; Dinoprostone; Escherichia coli; Fever;

2003
Involvement of eicosanoids in the hypothermic response to lipopolysaccharide during endotoxemia in rats.
    Prostaglandins, leukotrienes, and essential fatty acids, 2004, Volume: 70, Issue:1

    Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Eicosanoids; Endotoxemia; Fever; Hypoth

2004
[Fever and arthritis in a 36 year-old woman].
    Revista clinica espanola, 2004, Volume: 204, Issue:4

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Viral; Arthritis; Female; Fever; Humans;

2004
Interleukin (IL)-6, but not IL-1, induction in the brain downstream of cyclooxygenase-2 is essential for the induction of febrile response against peripheral IL-1alpha.
    Endocrinology, 2004, Volume: 145, Issue:11

    Topics: Animals; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Fe

2004
Indomethacin attenuates hyperthermia produced by anterior coronal lateral hypothalamic knife cuts.
    Brain research bulletin, 2004, Jul-30, Volume: 64, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain Injuries; Fever; Hypothala

2004
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2005, Volume: 288, Issue:3

    Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Re

2005
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
    Journal of ethnopharmacology, 2006, Nov-24, Volume: 108, Issue:2

    Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-

2006
Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms.
    European journal of pharmacology, 2006, Aug-14, Volume: 543, Issue:1-3

    Topics: Analgesics, Non-Narcotic; Animals; Arachidonic Acid; Body Temperature; Chemokine CCL3; Chemokine CCL

2006
CCL3/macrophage inflammatory protein-1alpha induces fever and increases prostaglandin E2 in cerebrospinal fluid of rats: effect of antipyretic drugs.
    Brain research, 2006, Sep-13, Volume: 1109, Issue:1

    Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Body Temperature; Body Temperature Regulati

2006
Hypoxia-induced sickness behaviour.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 8

    Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dinoprostone; Eating; Fever; Hypoxia; Indo

2006
Role of prostaglandins in heme-induced fever.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2006, Volume: 57 Suppl 8

    Topics: Animals; Body Temperature; Brain; Dinoprostone; Dose-Response Relationship, Drug; Fever; Heme; Immun

2006
Action of cyclooxygenase inhibitors and a leukotriene biosynthesis inhibitor on cisplatin-induced acute and delayed emesis in the ferret.
    Journal of pharmacological sciences, 2007, Volume: 103, Issue:2

    Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; D

2007
Endogenous opioids: role in prostaglandin-dependent and -independent fever.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 294, Issue:2

    Topics: Analgesics, Opioid; Animals; Cyclooxygenase Inhibitors; Fever; Indomethacin; Lipopolysaccharides; Ma

2008
Effects of intracerebroventricular floctafenine and indomethacin on body temperature in febrile rabbits.
    British journal of pharmacology, 1980, Volume: 71, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Fever; In Vitro Techniqu

1980
Increased intraocular pressure and hyperthermia following administration of substance P into rabbit third ventricle.
    Experimental eye research, 1982, Volume: 34, Issue:3

    Topics: Acetazolamide; Animals; Aqueous Humor; Body Temperature; Dose-Response Relationship, Drug; Fever; In

1982
Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit.
    Pharmacology, 1980, Volume: 20, Issue:6

    Topics: Animals; Body Temperature; Brain; Bucladesine; Cyproheptadine; Drug Interactions; Fever; Hydroxydopa

1980
Central versus peripheral sites of antipyretic action of a non-steroidal anti-inflammatory agent, AD-1590, in rabbits.
    Agents and actions, 1984, Volume: 15, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Catecholamines; Dibenzoxepins; Dinoprostone

1984
Relationship of trace metals to fever during infection: are prostaglandins involved?
    The American journal of physiology, 1983, Volume: 244, Issue:3

    Topics: Animals; Body Temperature; Endotoxins; Escherichia coli; Fever; Indomethacin; Male; Pasteurella Infe

1983
Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
    The New England journal of medicine, 1983, Mar-10, Volume: 308, Issue:10

    Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Humans; In Vitro Techniqu

1983
Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep.
    Pediatric research, 1983, Volume: 17, Issue:2

    Topics: Animals; Bacterial Toxins; Capillary Permeability; Cyclooxygenase Inhibitors; Fever; Granulocytes; H

1983
Activation of acute-phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs.
    Brain research bulletin, 1984, Volume: 12, Issue:6

    Topics: Animals; Body Temperature; Dinoprostone; Fever; Guinea Pigs; Indomethacin; Interleukin-1; Leukocytes

1984
Comparative effects of indoprofen and indomethacin on rat hypothalamic prostaglandin-synthetase activity.
    Research communications in chemical pathology and pharmacology, 1981, Volume: 32, Issue:2

    Topics: Animals; Cyclooxygenase Inhibitors; Fever; Hypothalamus; Indomethacin; Indoprofen; Phenylpropionates

1981
Effects of cloned interferon alpha 2 in normal volunteers: febrile reactions and changes in circulating corticosteroids and trace metals.
    Antimicrobial agents and chemotherapy, 1983, Volume: 23, Issue:4

    Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adult; Female; Fever; Humans; Indomethacin; Inte

1983
Hyperthermic responses to central injections of some peptide and non-peptide opioids in the guinea-pig.
    Neuropharmacology, 1983, Volume: 22, Issue:5

    Topics: Animals; Body Temperature; Endorphins; Fever; Guinea Pigs; Indomethacin; Iodipamide; Naloxone; Narco

1983
Influence of indomethacin on various immunopharmacological effects of muramyl dipeptide (MDP).
    Agents and actions. Supplements, 1980, Volume: 7

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Cattle; Cycloheximide; Fever; Glycopeptides; Guinea Pigs

1980
[Efficacy of indomethacin in neoplastic fever].
    La Nouvelle presse medicale, 1982, Jan-30, Volume: 11, Issue:4

    Topics: Adult; Female; Fever; Humans; Indomethacin; Neoplasms

1982
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-1982. Fever and subcutaneous masses in an elderly man.
    The New England journal of medicine, 1982, Apr-29, Volume: 306, Issue:17

    Topics: Adipose Tissue; Aged; Diagnosis, Differential; Fever; Humans; Indomethacin; Male; Panniculitis, Nodu

1982
Antipyretic effects of indomethacin in liver metastases of solid tumors.
    Cancer, 1982, Oct-01, Volume: 50, Issue:7

    Topics: Drug Administration Schedule; Female; Fever; Humans; Indomethacin; Liver Neoplasms; Male; Middle Age

1982
Control of fever associated with visceral cancers by indomethacin.
    Surgery, 1981, Volume: 89, Issue:4

    Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas

1981
Role of prostaglandin E in the biphasic fever response to endotoxin.
    The Journal of experimental medicine, 1981, Oct-01, Volume: 154, Issue:4

    Topics: Animals; Blood Pressure; Body Temperature; Carotid Arteries; Endotoxins; Female; Fever; Indomethacin

1981
Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide.
    The Journal of infectious diseases, 1980, Volume: 142, Issue:5

    Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Drug Synergism; Fever; Glycopeptides; Immunity, Innate;

1980
[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?].
    La Revue de medecine interne, 1995, Volume: 16, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Body Temperature; Diagnosis, Differential; Female; Fever; Humans; Hy

1995
Cyclic haemopoiesis at 7- or 8-day intervals.
    British journal of haematology, 1994, Volume: 88, Issue:1

    Topics: Adult; Anemia; C-Reactive Protein; Erythropoietin; Female; Fever; Granulocyte Colony-Stimulating Fac

1994
Neuromodulation of fever. A possible role for substance P.
    Annals of the New York Academy of Sciences, 1994, Nov-25, Volume: 741

    Topics: Animals; Fever; Guinea Pigs; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Lipopolysaccha

1994
Fever and the acute elevation in whole-body thermogenesis induced by lateral hypothalamic lesions.
    Physiology & behavior, 1995, Volume: 58, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Body Weight; Energy M

1995
Cyclo-oxygenase mediation of endotoxin-induced fever, anterior and posterior pituitary hormone release, and hypothalamic c-Fos expression in the prepubertal pig.
    Experimental physiology, 1995, Volume: 80, Issue:4

    Topics: Animals; Body Temperature; Endotoxins; Fever; Hormones; Hypothalamus; Indomethacin; Lipopolysacchari

1995
Restraint, but not frustration, induces prostaglandin-mediated hyperthermia in pigs.
    Physiology & behavior, 1995, Volume: 57, Issue:6

    Topics: Animals; Body Temperature; Fever; Food Deprivation; Frustration; Hydrocortisone; Indomethacin; Prost

1995
Zymosan-induced arthritis in rats. II. Effects of anti-inflammatory drugs.
    Life sciences, 1995, Volume: 56, Issue:20

    Topics: Animals; Arthritis; Cartilage, Articular; Dexamethasone; Edema; Fever; Indomethacin; Knee Joint; Mal

1995
Changes in plasma catecholamines during fever induced by bacterial endotoxin and interleukin-1 beta.
    The Japanese journal of physiology, 1994, Volume: 44, Issue:6

    Topics: Animals; Catecholamines; Endotoxins; Epinephrine; Fever; Indomethacin; Interleukin-1; Lipopolysaccha

1994
Prolonged fever and heterotopic ossification in a C4 tetraplegic patient. Case report.
    Paraplegia, 1995, Volume: 33, Issue:3

    Topics: Adult; Fever; Hip; Humans; Indomethacin; Leukocyte Count; Magnetic Resonance Imaging; Male; Ossifica

1995
Fever produced by interleukin-11 (IL-11) injected into the anterior hypothalamic pre-optic area of the rat is antagonized by indomethacin.
    Neuropharmacology, 1994, Volume: 33, Issue:8

    Topics: Animals; Body Temperature; Body Weight; Eating; Fever; Humans; Indomethacin; Interleukin-11; Male; M

1994
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
    British journal of pharmacology, 1995, Volume: 114, Issue:2

    Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hy

1995
Elevation of plasma ACTH concentration in rabbits made febrile by systemic injection of bacterial endotoxin.
    Brain research, 1994, Aug-01, Volume: 652, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Corticotropin-Releasing Hormone; Dinoproston

1994
Interleukin-1 beta production in the rabbit brain during endotoxin-induced fever.
    The Journal of physiology, 1994, Apr-01, Volume: 476, Issue:1

    Topics: Animals; Bacterial Toxins; Brain Chemistry; Cerebral Ventricles; Endotoxins; Fever; Immunohistochemi

1994
A retrospective analysis of the effect of indomethacin on adverse reactions to orthoclone OKT3 in the therapy of acute renal allograft rejection.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1994, Volume: 24, Issue:3

    Topics: Acute Disease; Adult; Female; Fever; Graft Rejection; Humans; Indomethacin; Kidney Transplantation;

1994
Interleukin-8 induces fever by a prostaglandin-independent mechanism.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Animals; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Dexamethasone; Fever; H

1994
Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice.
    The American journal of physiology, 1994, Volume: 266, Issue:1 Pt 2

    Topics: Animals; Body Temperature; Body Weight; Feeding Behavior; Fever; Indomethacin; Lipopolysaccharides;

1994
Vasopressin release within the ventral septal area of the rat brain during drug-induced antipyresis.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 2

    Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Fever; Indome

1993
Dexamethasone inhibits the pyrogenic activity of prostaglandin F2 alpha, but not prostaglandin E2.
    European journal of pharmacology, 1993, Jul-20, Volume: 238, Issue:2-3

    Topics: Animals; Body Temperature; Dexamethasone; Dinoprost; Dinoprostone; Fever; Indomethacin; Injections,

1993
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
    General pharmacology, 1993, Volume: 24, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena

1993
Prostaglandin-dependent c-Fos expression in the median preoptic nucleus of pigs subjected to restraint: correlation with hyperthermia.
    Neuroscience letters, 1995, Sep-22, Volume: 198, Issue:1

    Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Fever; Gene Expression Regulation;

1995
Indomethacin blocks the febrile response induced by interleukin-8 in rabbits.
    The American journal of physiology, 1995, Volume: 269, Issue:6 Pt 2

    Topics: Animals; Cyclooxygenase Inhibitors; Fever; Humans; Indomethacin; Injections, Intravenous; Injections

1995
Development of hyperthermia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists.
    British journal of pharmacology, 1996, Volume: 117, Issue:4

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Fever; Indomethacin; Injections, Intraventricu

1996
Nitric oxide synthase-cyclo-oxygenase pathways in organum vasculosum laminae terminalis: possible role in pyrogenic fever in rabbits.
    British journal of pharmacology, 1996, Volume: 118, Issue:1

    Topics: Animals; Body Temperature Regulation; Cyclic GMP; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme In

1996
A case of adult onset Still's disease presenting with fever and a rash.
    Annals of the Academy of Medicine, Singapore, 1996, Volume: 25, Issue:2

    Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; F

1996
Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists.
    Immunopharmacology, 1996, Volume: 33, Issue:1-3

    Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Fever; Hyperalgesia; Indomethacin; Inflammatio

1996
Indomethacin attenuation of radiation-induced hyperthermia does not modify radiation-induced motor hypoactivity.
    Journal of radiation research, 1996, Volume: 37, Issue:3

    Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Fever; Indomethacin; Male; Motor Ac

1996
Role of central interleukin-1 beta in gastrointestinal motor disturbances induced by lipopolysaccharide in sheep.
    Digestive diseases and sciences, 1997, Volume: 42, Issue:2

    Topics: Animals; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Escherichia coli; Female; Fever

1997
Effect of pre-induction of heat shock proteins on indomethacin-induced small-intestinal lesion in rats.
    Journal of gastroenterology, 1997, Volume: 32, Issue:1

    Topics: Animals; Fever; Heat-Shock Proteins; Indomethacin; Intestine, Small; Male; Rats; Rats, Sprague-Dawle

1997
Role of substance P (SP) in the mediation of endotoxin (LPS) fever in rats.
    Annals of the New York Academy of Sciences, 1997, Mar-15, Volume: 813

    Topics: Alprostadil; Animals; Female; Fever; Indomethacin; Injections, Intraventricular; Lipopolysaccharides

1997
Hypothalamic prostaglandin E2 during lipopolysaccharide-induced fever in guinea pigs.
    Brain research bulletin, 1996, Volume: 39, Issue:6

    Topics: Animals; Blood-Brain Barrier; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Guinea Pigs; Hypothala

1996
Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation.
    The American journal of physiology, 1997, Volume: 272, Issue:4 Pt 2

    Topics: Animals; Anorexia; Behavior, Animal; Body Temperature; Body Weight; Cachexia; Coconut Oil; Fatty Aci

1997
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
    British journal of pharmacology, 1997, Volume: 121, Issue:1

    Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetinae; Cyclo

1997
Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits.
    Infection and immunity, 1997, Volume: 65, Issue:7

    Topics: Animals; Anisomycin; Anti-Inflammatory Agents; Body Temperature; Dexamethasone; Enterotoxins; Fever;

1997
Circadian rhythm of fever induced by interferon-alpha in mice.
    Life sciences, 1997, Volume: 61, Issue:8

    Topics: Analgesics, Non-Narcotic; Animals; Circadian Rhythm; Fever; Indomethacin; Interferon-alpha; Male; Mi

1997
Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs.
    The American journal of physiology, 1997, Volume: 273, Issue:3 Pt 2

    Topics: Analgesics, Non-Narcotic; Animals; Body Temperature Regulation; Dexamethasone; Endotoxins; Escherich

1997
From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.
    Advances in experimental medicine and biology, 1997, Volume: 407

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromium Radioisotopes; Cyclooxygenas

1997
Extracts of rhinoceros horn are not antipyretic in rabbits.
    Journal of basic and clinical physiology and pharmacology, 1997, Volume: 8, Issue:1-2

    Topics: Analgesics, Non-Narcotic; Animals; Female; Fever; Horns; Indomethacin; Male; Medicine, Chinese Tradi

1997
A role for gastrointestinal endotoxins in enhancement of heat tolerance by physical fitness.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Endotoxins; Fever; Hemodynamics;

1998
Comparison of the antipyretic actions of indomethacin and L-745,337, a selective cyclooxygenase-2 inhibitor, in endotoxin-treated prepubertal pigs.
    General pharmacology, 1998, Volume: 30, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Body Temperature; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors;

1998
Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient.
    The Journal of infection, 1997, Volume: 35, Issue:3

    Topics: Actinobacillus; Actinobacillus Infections; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis,

1997
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:1

    Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1998
Neoplastic fever: choice of antipyrogenic therapy makes a difference.
    Geriatrics, 1998, Volume: 53, Issue:8

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Fever; Humans; Indomethacin

1998
Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Animals; Antioxidants; Arachidonic Acid; Body Temperature; Body Temperature Regulation; Clotrimazole

1998
Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats.
    British journal of pharmacology, 1998, Volume: 125, Issue:3

    Topics: Animals; Endothelin Receptor Antagonists; Escherichia coli; Fever; Indomethacin; Injections, Intrave

1998
Antiinflammatory potency of dehydrocurdione, a zedoary-derived sesquiterpene.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47, Issue:12

    Topics: Acetic Acid; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Arthritis, Exp

1998
Effect of indomethacin on hyperthermia induced by heat stress in broiler chickens.
    International journal of biometeorology, 1998, Volume: 42, Issue:2

    Topics: Animals; Body Temperature; Chickens; Cyclooxygenase Inhibitors; Fever; Heat Stress Disorders; Indome

1998
Polysaccharide mannan components of Candida albicans and Saccharomyces cerevisiae cell wall produce fever by intracerebroventricular injection in rats.
    Brain research bulletin, 1999, Mar-15, Volume: 48, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Candida albicans; Cytokines; Fev

1999
Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia.
    Prostaglandins, leukotrienes, and essential fatty acids, 1999, Volume: 60, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cyclooxygenase Inhibitors; Dinop

1999
Cardiorespiratory responses to interleukin-1beta in adult rats: role of nitric oxide, eicosanoids and glucocorticoids.
    Archives of physiology and biochemistry, 1999, Volume: 107, Issue:2

    Topics: Animals; Blood Pressure; Body Temperature; Cyclooxygenase Inhibitors; Dexamethasone; Eicosanoids; En

1999
Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way.
    Journal of applied physiology (Bethesda, Md. : 1985), 2000, Volume: 88, Issue:5

    Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclooxygenase Inhibitors; Deute

2000
Endotoxaemia does not limit heat tolerance in rats: the role of plasma lipoproteins.
    European journal of applied physiology, 2000, Volume: 82, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Body Temperature; Brain; Endotox

2000
Involvement of CRH in fever induced by a distinct pre-formed pyrogenic factor (PFPF).
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2000, Volume: 49, Issue:9

    Topics: Animals; Chemokine CCL4; Corticotropin-Releasing Hormone; Fever; Indomethacin; Interleukin-8; Macrop

2000
Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages.
    European cytokine network, 2000, Volume: 11, Issue:4

    Topics: Animals; Cells, Cultured; Cytokines; Fever; Indomethacin; Interleukin-6; Isoelectric Focusing; Lipop

2000
Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma.
    American journal of hematology, 2001, Volume: 66, Issue:3

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Fever; Humans; Indomethacin; Lymph Nodes; Lymphoma, B

2001
Analgesic and antipyretic activities of Rumex patientia extract on mice and rabbits.
    Die Pharmazie, 2001, Volume: 56, Issue:10

    Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Aspirin; Fever; Formaldehyde; Indomethacin; L

2001
Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs.
    Neuroimmunomodulation, 2001, Volume: 9, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Cyclooxygenase 1; Cycl

2001
Benorylate interaction with indomethacin and phenylbutazone.
    Archives internationales de pharmacodynamie et de therapie, 1976, Volume: 219, Issue:1

    Topics: Animals; Arthritis; Aspirin; Drug Interactions; Drug Synergism; Fever; Indomethacin; Male; Phenylbut

1976
Effects of prostaglandin antagonism on sodium arachidonate fever in rabbits.
    The Journal of physiology, 1977, Volume: 267, Issue:2

    Topics: Animals; Arachidonic Acids; Body Temperature; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-c

1977
Endotoxin fever in the new-born guinea-pig and the modulating effects of indomethacin and p-chlorophenylalanine.
    The Journal of physiology, 1978, Volume: 281

    Topics: Animals; Animals, Newborn; Body Temperature; Endotoxins; Escherichia coli; Fenclonine; Fever; Guinea

1978
Endotoxin fever in the newborn kitten. The role of prostaglandins and monoamines.
    Acta physiologica Academiae Scientiarum Hungaricae, 1979, Volume: 54, Issue:3

    Topics: Animals; Body Temperature; Cats; Endotoxins; Escherichia coli; Fenclonine; Fever; Indomethacin; Nore

1979
Effect of antipyretics on group A streptococcal pyrogenic exotoxin fever production and ability to enhance lethal endotoxin shock.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1978, Volume: 157, Issue:3

    Topics: Animals; Aspirin; Cortisone; Drug Synergism; Endotoxins; Exotoxins; Fever; Indomethacin; Prostagland

1978
Role of prostaglandins in mediation of pyrogen fever.
    The Indian journal of medical research, 1979, Volume: 70

    Topics: Animals; Fever; Indomethacin; Methysergide; Prostaglandins E; Rabbits; Rats; Stomach; Typhoid-Paraty

1979
Increase in body temperature during carrageenin-induced paw oedema in the rat. Effect of non-steroid anti-inflammatory substances and essential fatty acid deficiency.
    Prostaglandins and medicine, 1979, Volume: 2, Issue:5

    Topics: Acetaminophen; Aging; Animals; Anti-Inflammatory Agents; Brain Chemistry; Carrageenan; Edema; Fatty

1979
Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit.
    Experientia, 1977, Dec-15, Volume: 33, Issue:12

    Topics: Animals; Arachidonic Acids; Body Temperature; Cyproheptadine; Fever; Hydroxydopamines; Indomethacin;

1977
Antagonism by indomethacin of neurogenic hyperthermia produced by unilateral puncture of the anterior hypothalamic/preoptic region.
    The Journal of physiology, 1977, Volume: 272, Issue:3

    Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Fever; Hypothalamus; Hypothalamus, Ante

1977
A primate model for the study of human fever.
    The Journal of infectious diseases, 1975, Volume: 132, Issue:2

    Topics: Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Dose-Response Relationship, Dru

1975
Postoperative fever in patients with hematologic malignancy.
    International surgery, 1977, Volume: 62, Issue:4

    Topics: Adult; Aged; Colonic Neoplasms; Female; Fever; Humans; Indomethacin; Leukemia; Male; Neoplasms, Mult

1977
Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin.
    The Journal of rheumatology, 1977,Summer, Volume: 4, Issue:2

    Topics: Drug Evaluation; Fever; Humans; Indomethacin; Joint Diseases; Male; Middle Aged; Muscular Diseases;

1977
Oral antipyretic therapy.
    Scandinavian journal of rheumatology, 1976, Volume: 5, Issue:2

    Topics: Acetaminophen; Administration, Oral; Aminopyrine; Aspirin; Child; Child, Preschool; Drug Evaluation;

1976
Antagonism by antipyretics of the hyperthermic effect of a prostaglandin precursor, sodium arachidonate, in the cat.
    The Journal of physiology, 1976, Volume: 257, Issue:3

    Topics: Acetaminophen; Analgesics; Animals; Arachidonic Acids; Body Temperature; Cats; Fever; Indomethacin;

1976
Some pharmacological and toxicological studies on ketoprofen.
    Rheumatology and rehabilitation, 1976, Volume: Suppl

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indometha

1976
[Modification of experimental etiocholanolone fever through indomethacin].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1976, Volume: 82 Pt 2

    Topics: Adult; Etiocholanolone; Fever; Humans; Indomethacin

1976
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:11

    Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap

1975
[Etiocholanolone fever].
    Die Medizinische Welt, 1975, Mar-07, Volume: 26, Issue:10

    Topics: Adult; Diagnosis, Differential; Etiocholanolone; Female; Fever; Fever of Unknown Origin; Humans; Ind

1975
The antipyretic effect of indomethacin.
    The Journal of physiology, 1975, Volume: 248, Issue:3

    Topics: Animals; Body Temperature; Brain; Cats; Cerebral Ventricles; Dose-Response Relationship, Drug; Fever

1975
Chemistry and pharmacology of naproxen.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:2A

    Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed

1975
Prostaglandins, endotoxin and lipid A on body temperature in rats.
    The Journal of physiology, 1975, Volume: 249, Issue:3

    Topics: Acetaminophen; Animals; Body Temperature; Cerebral Ventricles; Endotoxins; Female; Fever; Indomethac

1975
The antipyretic effect of suprofen in rats with yeast-induced fever.
    Arzneimittel-Forschung, 1975, Volume: 25, Issue:10

    Topics: Analgesics; Animals; Aspirin; Body Temperature; Dose-Response Relationship, Drug; Drug Evaluation, P

1975
Effects of interleukin-1 beta on blood pressure, sympathetic nerve activity, and pituitary endocrine functions in anesthetized rats.
    American journal of hypertension, 1992, Volume: 5, Issue:4 Pt 1

    Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Blood Pressure; Dose-Response Relationsh

1992
Indomethacin and sodium carbonate effects on conditioned fever and NK cell activity.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:2

    Topics: Animals; Body Temperature; Carbonates; Conditioning, Psychological; Female; Fever; Indomethacin; Kil

1992
Quantitative aspects of the fever response elicited by intracerebral injection of endotoxin in the guinea-pig.
    Physiological research, 1992, Volume: 41, Issue:1

    Topics: Analysis of Variance; Animals; Endotoxins; Fever; Guinea Pigs; Indomethacin; Injections; Lipopolysac

1992
Characteristics of TNF alpha- and TNF beta-induced fever in the rabbit.
    The Japanese journal of physiology, 1992, Volume: 42, Issue:1

    Topics: Animals; Body Temperature; Fever; Indomethacin; Injections, Intravenous; Injections, Intraventricula

1992
The fever induced by polyriboinosinic:polyribocytidylic acid is not related to interferon synthesis in the rabbit's hypothalamus.
    Journal of interferon research, 1991, Volume: 11, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cells, Cultured; Cycloheximide;

1991
The effect of indomethacin on the febrile response following OKT3 therapy.
    Transplantation, 1992, Volume: 53, Issue:1

    Topics: Adolescent; Adult; Creatinine; Drug Therapy, Combination; Female; Fever; Graft Rejection; Humans; In

1992
Characterization and mechanism of fever induction by interleukin-1 beta.
    Pflugers Archiv : European journal of physiology, 1991, Volume: 419, Issue:6

    Topics: Animals; Arachidonic Acid; Dose-Response Relationship, Drug; Fever; Humans; Indomethacin; Injections

1991
Leukotrienes in cerebrospinal fluid of the conscious cat: effect of platelet-activating factor and pyrogens.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1991, Volume: 21A

    Topics: Animals; Cats; Diterpenes; Endotoxins; Fever; Ginkgolides; Indomethacin; Interleukin-1; Lactones; Le

1991
Hypothalamic indomethacin fails to block fever induced in rats by central macrophage inflammatory protein-1 (MIP-1).
    Pharmacology, biochemistry, and behavior, 1991, Volume: 39, Issue:2

    Topics: Animals; Body Temperature Regulation; Chemokine CCL4; Cytokines; Electrophoresis, Polyacrylamide Gel

1991
Neuromodulation of fever: apparent involvement of opioids.
    Brain research bulletin, 1991, Volume: 26, Issue:2

    Topics: Animals; Fever; Guinea Pigs; Indomethacin; Interleukin-6; Lipopolysaccharides; Male; Naloxone; Tumor

1991
Indomethacin suppositories for pyrexia in children.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1991, Mar-16, Volume: 79, Issue:6

    Topics: Child; Fever; Humans; Indomethacin; Suppositories

1991
Temperature-dependent modulation of lipopolysaccharide-induced interleukin-1 beta and tumor necrosis factor alpha expression in cultured human astroglial cells by dexamethasone and indomethacin.
    The Journal of clinical investigation, 1991, Volume: 87, Issue:5

    Topics: Astrocytes; Cells, Cultured; Dexamethasone; Fever; Humans; Indomethacin; Interleukin-1; Lipopolysacc

1991
Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation.
    Agents and actions. Supplements, 1991, Volume: 32

    Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Collagen; Edem

1991
Macrophage inflammatory protein-1: unique action on the hypothalamus to evoke fever.
    Brain research bulletin, 1990, Volume: 24, Issue:6

    Topics: Animals; Chemotactic Factors; Fever; Hypothalamus; Indomethacin; Interleukin-8; Male; Prostaglandins

1990
Central action sites of interleukin-1 beta for inducing fever in rabbits.
    The Journal of physiology, 1990, Volume: 428

    Topics: Animals; Blood-Brain Barrier; Brain; Fever; Indomethacin; Injections, Intravenous; Injections, Intra

1990
Role of interleukin 6 in fever in rats.
    The American journal of physiology, 1990, Volume: 258, Issue:3 Pt 2

    Topics: Animals; Body Temperature; Cerebral Ventricles; Fever; Indomethacin; Injections, Intraperitoneal; In

1990
Suppression of tumor necrosis factor alpha production by a human immunoglobulin preparation for intravenous use.
    Infection and immunity, 1990, Volume: 58, Issue:5

    Topics: Animals; Dinoprostone; Fever; Gene Expression; Immunoglobulins; Indomethacin; Infusions, Intravenous

1990
Influence of nonsteroid anti-inflammatory drugs on lymphocyte subpopulation and on the primary humoral response in normothermic and feverish rabbits.
    Archivum immunologiae et therapiae experimentalis, 1989, Volume: 37, Issue:5-6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Dose-Response Relatio

1989
Activation of ACTH release is mediated by the same molecule as the final mediator, PGE2, of febrile response in rats.
    Brain research, 1989, Jan-23, Volume: 478, Issue:1

    Topics: Adrenocorticotropic Hormone; Animals; Corticotropin-Releasing Hormone; Dinoprostone; Dose-Response R

1989
Possible involvement of prostaglandin E in development of ACTH response in rats induced by human recombinant interleukin-1.
    The Journal of physiology, 1989, Volume: 411

    Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Dinoprostone; Dose-Response Relationship, Dr

1989
Neurogenic hyperthermia in subarachnoid hemorrhage.
    Southern medical journal, 1989, Volume: 82, Issue:12

    Topics: Adult; Combined Modality Therapy; Cyproheptadine; Fever; Humans; Indomethacin; Ischemic Attack, Tran

1989
Adult Still's disease: a missed diagnosis.
    Singapore medical journal, 1989, Volume: 30, Issue:2

    Topics: Adult; Arthritis, Gouty; Arthritis, Juvenile; Female; Fever; Humans; Indomethacin; Male; Naproxen

1989
Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens.
    The American journal of physiology, 1989, Volume: 256, Issue:3 Pt 2

    Topics: Animals; Body Temperature; Cats; Dinoprostone; Endotoxins; Female; Fever; Hypothalamus; Indomethacin

1989
Central vasopressin V1-receptors mediate indomethacin-induced antipyresis in rats.
    The American journal of physiology, 1989, Volume: 256, Issue:5 Pt 2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Temperature; Brain; Fev

1989
The pathogenesis of cianidanol-induced fever.
    European journal of clinical pharmacology, 1988, Volume: 34, Issue:3

    Topics: Catechin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fever; Humans; Indomethacin; Interleukin-1; Macropha

1988
Effect of single oral doses of ascorbic acid on body temperature in healthy guinea pigs.
    The Journal of nutrition, 1989, Volume: 119, Issue:3

    Topics: Animals; Ascorbic Acid; Body Temperature; Fever; Guinea Pigs; Indomethacin; Male; Prostaglandins

1989
Indomethacin is effective against neurogenic hyperthermia following cranial trauma or brain surgery.
    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1987, Volume: 14, Issue:2

    Topics: Body Temperature; Brain; Brain Injuries; Dipyrone; Drug Resistance; Fever; Humans; Indomethacin; Pos

1987
Fever is not responsible for the elevated glucose kinetics in sepsis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 185, Issue:4

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibito

1987
Hyperthermia increases cerebral metabolic rate and blood flow in neonatal pigs.
    The American journal of physiology, 1988, Volume: 255, Issue:2 Pt 2

    Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Energ

1988
Inhibition of postpyrogenic increase of phagocytic and killing activity of neutrophils by nonsteroid antiinflammatory drugs.
    Archivum immunologiae et therapiae experimentalis, 1988, Volume: 36, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Fever;

1988
Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1988, Volume: 8, Issue:2

    Topics: Animals; Body Temperature; Brain; Dexamethasone; Fever; Glucose; Indomethacin; Interleukin-1; Male;

1988
Effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits.
    The American journal of physiology, 1988, Volume: 255, Issue:4 Pt 2

    Topics: Animals; Body Temperature; Cerebral Ventricles; Dose-Response Relationship, Drug; Fever; Indomethaci

1988
Vasopressor responses and hyperthermia by intracerebroventricular injections of penicillin, a pyrogen, in rats: involvement of brain angiotensin II.
    American journal of hypertension, 1988, Volume: 1, Issue:3 Pt 3

    Topics: Angiotensin II; Animals; Blood Pressure; Brain; Consciousness; Desoxycorticosterone; Drinking; Fever

1988
Effect of different treatments of the endotoxin-induced modifications in serum iron levels.
    General pharmacology, 1986, Volume: 17, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endotoxins; Female; Fever; Indomethacin; Iron; Ket

1986
Vasopressin functions as an endogenous antipyretic in the newborn.
    Biology of the neonate, 1987, Volume: 51, Issue:5

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Tempe

1987
The antipyretic effects of centrally administered vasopressin at different ambient temperatures.
    Brain research, 1987, Jul-14, Volume: 415, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Temperature; Brain; Fev

1987
Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents.
    Drugs under experimental and clinical research, 1987, Volume: 13, Issue:5

    Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental;

1987
Pharmacological properties of N-methoxy-3-(3,5-ditert-butyl-4-hydroxybenzylidene)-2-pyrrolidone (E-5110), a novel nonsteroidal antiinflammatory agent.
    Agents and actions, 1987, Volume: 21, Issue:3-4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Fever; Indomethacin; Inflammation; Pain; Piroxicam

1987
Fever induced in rabbits by intraventricular injection of rabbit and human serum albumin.
    The Journal of physiology, 1987, Volume: 390

    Topics: Animals; Blood Cell Count; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever;

1987
Further evidence that stress hyperthermia is a fever.
    Physiology & behavior, 1987, Volume: 39, Issue:6

    Topics: Animals; Body Temperature; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intraventri

1987
Migration of isolated rabbit lymphocytes in the course of pharmacological inhibition of pyrogenic fever.
    Archivum immunologiae et therapiae experimentalis, 1985, Volume: 33, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Escherichia coli; Fever; Indomethacin; In

1985
Familial nephropathic amyloidosis associated with indomethacin responsive fever.
    Proceedings of the European Dialysis and Transplant Association - European Renal Association. European Dialysis and Transplant Association - European Renal Association. Congress, 1985, Volume: 21

    Topics: Amyloidosis; Female; Fever; Genes, Dominant; Humans; Indomethacin; Kidney Diseases; Middle Aged

1985
Differences in endogenous pyrogen fevers induced by iv and icv routes in rabbits.
    Journal of applied physiology (Bethesda, Md. : 1985), 1985, Volume: 59, Issue:2

    Topics: Animals; Fever; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Interleukin-1;

1985
[Action of indomethacin on fever in cancer patients].
    Therapeutique (La Semaine des hopitaux), 1971, Volume: 47, Issue:3

    Topics: Adolescent; Adult; Aged; Female; Fever; Humans; Indomethacin; Infections; Male; Middle Aged; Neoplas

1971
Aspirin-like drugs and prostaglandins.
    Lancet (London, England), 1971, Aug-14, Volume: 2, Issue:7720

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Fever; Humans; Indomethacin; Injections, Spinal; P

1971
Symptomatic control of fever in lymphoma and leukemia.
    Mayo Clinic proceedings, 1969, Volume: 44, Issue:4

    Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Aspirin; Female; Fever; Hodgkin Disease; Humans; I

1969
Further studies on the role of prostaglandin in fever.
    The Journal of physiology, 1974, Volume: 241, Issue:3

    Topics: Acetaminophen; Animals; Body Temperature; Calcium; Cats; Cerebral Ventricles; Cerebrospinal Fluid; C

1974
The hyperthermic effect of intracerebroventricular cholera enterotoxin in the unanaesthetized cat.
    The Journal of physiology, 1974, Volume: 240, Issue:2

    Topics: Acetaminophen; Animals; Body Temperature; Bucladesine; Cats; Cerebral Ventricles; Consciousness; Cyc

1974
Proceedings: Lipid A and prostaglandin.
    The Journal of physiology, 1974, Volume: 239, Issue:2

    Topics: Acetaminophen; Animals; Aspirin; Cats; Endotoxins; Fever; Indomethacin; Lipids; Prostaglandins

1974
Carrageenin hyperthermia in rats.
    Experientia, 1974, Nov-15, Volume: 30, Issue:11

    Topics: Animals; Aspirin; Body Temperature; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fe

1974
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
    Arzneimittel-Forschung, 1974, Volume: 24, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev

1974
Use of Indomethacin as an anti-pyretic agent in malignant reticulosis.
    The Medical journal of Malaya, 1972, Volume: 26, Issue:3

    Topics: Adolescent; Adult; Child; Evaluation Studies as Topic; Female; Fever; Hodgkin Disease; Humans; Indom

1972
Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats.
    The Journal of physiology, 1973, Volume: 234, Issue:2

    Topics: Acetaminophen; Animals; Aspirin; Body Temperature; Cats; Cerebral Ventricles; Chromatography, Thin L

1973
Granulomatous hepatitis and prolonged fever of unknown origin: a study of 13 patients.
    Medicine, 1973, Volume: 52, Issue:1

    Topics: Adult; Ascites; Dexamethasone; Edema; Female; Fever; Fever of Unknown Origin; Granuloma; Hepatitis;

1973
[Recurring fever bouts].
    Deutsche medizinische Wochenschrift (1946), 1973, Mar-02, Volume: 98, Issue:9

    Topics: Etiocholanolone; Familial Mediterranean Fever; Fever; Humans; Indomethacin; Male; Middle Aged; Recur

1973
Pharmacological study on a new analgesic-anti-inflammatory drug: alpha-(4-(1-oxo-2-iso-indolinyl)-phenyl)-propionic acid of K 4277.
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:8

    Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Behavi

1973
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
    Arzneimittel-Forschung, 1973, Volume: 23, Issue:9

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr

1973
Antipyretic effect of indomethacin in patients with malignancy.
    Cancer, 1968, Volume: 21, Issue:4

    Topics: Anti-Bacterial Agents; Body Temperature; Female; Fever; Hodgkin Disease; Humans; Indomethacin; Leuke

1968
Anti-inflammatory and other properties of 2,3-dihydrol-1-H-pyridino-(2,3- b) (1,4)-thiazine-2-one; ABBott-29590.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:2

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dogs; Edema; Fever; Gastric Mucos

1972
[Indomethacin in combination with anticoagulants in the treatment thrombophlebitis].
    Minerva medica, 1972, Jan-17, Volume: 63, Issue:3

    Topics: Aged; Anticoagulants; Drug Combinations; Edema; Female; Fever; Humans; Indomethacin; Male; Pain; Thr

1972
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid;

1972
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 7. Pharmacological comparison with standard anti-inflammatory drugs.
    Arzneimittel-Forschung, 1972, Volume: 22, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Edema; Female; Fever; Flufenamic Acid; Indometh

1972
Fever responses to bacterial pyrogens in guinea pigs and application for screening of antipyretic agents.
    Japanese journal of pharmacology, 1968, Volume: 18, Issue:1

    Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Body Temperature; Female; Fever; Flufenami

1968
[On the therapy of etiocholanolone fever].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1967, Volume: 73

    Topics: Adolescent; Adult; Betamethasone; Child; Etiocholanolone; Female; Fever; Humans; Indomethacin; Male;

1967
Indomethacin: as an antipyretic agent in pediatrics.
    Clinical pediatrics, 1968, Volume: 7, Issue:2

    Topics: Analgesics; Animals; Body Temperature; Child; Fever; Humans; Indomethacin; Rabbits; Rats; Time Facto

1968
The assay of anti-pyretic drugs in mice, using intracerebral injection of pyretogenins.
    British journal of pharmacology, 1968, Volume: 34, Issue:1

    Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Biological Assay; Body Temperature; Cerebra

1968
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
    Arzneimittel-Forschung, 1969, Volume: 19, Issue:6

    Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car

1969
Control of fever in Hodgkin's disease by indomethacin.
    JAMA, 1965, Nov-08, Volume: 194, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Female; Fever

1965
[On the antipyretic action of indomethacin in Hodgkin's lymphogranuloma and in neoplasms].
    Minerva medica, 1966, Sep-05, Volume: 57, Issue:71

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Fever; Hodgkin Disease; Human

1966