indomethacin has been researched along with Pyrexia in 228 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Excerpt | Relevance | Reference |
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"Substance P (SP) is involved in fever that is induced by lipopolysaccharide (LPS) but not by interleukin-1β or macrophage inflammatory protein-1α." | 7.83 | Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever. ( Barbosa, FL; Borges, BS; Brito, HO; Fraga, D; Franco, CRC; Reis, RCD; Zampronio, AR, 2016) |
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively." | 7.80 | Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014) |
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)." | 7.73 | The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005) |
"Intraperitoneal indomethacin at 10 mg kg(-1) attenuated both phases of intravenous LPS (2 microg kg(-1)) fever, but the first more so than the second; at 50 mg kg(-1), it inhibited the febrile response completely." | 7.71 | Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs. ( Blatteis, CM; Li, S; Llanos-Q, J; Steiner, AA, 2001) |
"A 77-year-old man with relapsed non-Hodgkin's lymphoma, diffuse large B-cell type, was treated with naproxen, a nonsteroidal anti-inflammatory drug (NSAID), for paraneoplastic fever." | 7.71 | Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma. ( Iwabe, K; Kobayashi, S; Masuda, M; Mizoguchi, H; Motoji, T; Teramura, M; Yoshinaga, K, 2001) |
"We have studied the mechanism by which interleukin-8 (IL-8) induces fever in rats." | 7.69 | Interleukin-8 induces fever by a prostaglandin-independent mechanism. ( Cunha, FQ; Ferreira, SH; Silva, CA; Souza, GE; Zampronio, AR, 1994) |
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin." | 7.69 | [Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995) |
" This case report and review concerns a patient with Sweet's syndrome in whom dramatic relief of severe arthralgias, myalgias, and painful skin lesions occurred using indomethacin." | 7.65 | Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin. ( Hoffman, GS, 1977) |
"Fever is frequently a symptom in patients suffering from cancer and in most cases it is related to infections or complications of the treatment." | 6.67 | [Antipyretic effect of indomethacin vs aspirin in fever of tumor origin]. ( Asef, SG; Berbotto, GA; Elias, G; Ostoich, MT; Teglia, O, 1993) |
"Substance P (SP) is involved in fever that is induced by lipopolysaccharide (LPS) but not by interleukin-1β or macrophage inflammatory protein-1α." | 3.83 | Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever. ( Barbosa, FL; Borges, BS; Brito, HO; Fraga, D; Franco, CRC; Reis, RCD; Zampronio, AR, 2016) |
"The antipyretic and hypothermic prodrug dipyrone prevents PGE2 -dependent and -independent fever induced by LPS from Escherichia coli and Tityus serrulatus venom (Tsv) respectively." | 3.80 | Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever. ( Aguiar, FA; Assis, DC; Clososki, GC; de Melo, MC; de Souza, GE; Ferreira, SH; Jabor, VA; Kalapothakis, E; Malvar, Ddo C; Vaz, Ade L, 2014) |
" The oral administration of the Chantaleela recipe reduced ulcer formation in acute gastric ulcer models (EtOH/HCl-, indomethacin-, and stress-induced gastric lesions)." | 3.78 | Anti-inflammatory and anti-ulcerogenic activities of Chantaleela recipe. ( Jaijoy, K; Khonsung, P; Nanna, U; Piyabhan, P; Sireeratawong, S; Soonthornchareonnon, N, 2012) |
"This study compared the antipyretic effects of ibuprofen and indomethacin regarding the efficacy in blocking fevers induced by lipopolysaccharide (LPS from E." | 3.77 | Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin V₁ receptors. ( Cristofoletti, R; Fabricio, AS; Lindsey, CJ; Melo, MC; Soares, DM; Souza, GE; Veiga-Souza, FH, 2011) |
"Bacterial lipopolysaccharide (LPS) induces fever through two parallel pathways; one, prostaglandin (PG)-dependent and the other, PG-independent and involving endothelin-1 (ET-1)." | 3.77 | The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus. ( de Souza, GE; Fabrício, AS; Figueiredo, MJ; Kanashiro, A; Machado, RR; Malvar, Ddo C; Rae, GA; Soares, DM, 2011) |
" The anti- oedema effect was compared with indomethacin." | 3.76 | Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum. ( Antonisamy, P; Ignacimuthu, S, 2010) |
"It was previously shown that sustained fever can be induced in rats by central injection of endothelin-1 (ET-1)." | 3.73 | The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. ( Cristofoletti, R; Fabricio, AS; Navarra, P; Souza, GE; Veiga, FH, 2005) |
" This study was undertaken to elucidate the effects of the COX-inhibitor Indomethacin (INDO) and the selective FLAP inhibitor MK-886 on LPS-induced hypothermia, mortality and increase in production of hypothalamic prostaglandin E(2) (PGE(2)) and leukotriene during endotoxemia." | 3.72 | Involvement of eicosanoids in the hypothermic response to lipopolysaccharide during endotoxemia in rats. ( Azab, AN; Kaplanski, J, 2004) |
"Intraperitoneal indomethacin at 10 mg kg(-1) attenuated both phases of intravenous LPS (2 microg kg(-1)) fever, but the first more so than the second; at 50 mg kg(-1), it inhibited the febrile response completely." | 3.71 | Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs. ( Blatteis, CM; Li, S; Llanos-Q, J; Steiner, AA, 2001) |
"A 77-year-old man with relapsed non-Hodgkin's lymphoma, diffuse large B-cell type, was treated with naproxen, a nonsteroidal anti-inflammatory drug (NSAID), for paraneoplastic fever." | 3.71 | Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma. ( Iwabe, K; Kobayashi, S; Masuda, M; Mizoguchi, H; Motoji, T; Teramura, M; Yoshinaga, K, 2001) |
"A novel pre-formed pyrogenic factor (PFPF), released by LPS-stimulated macrophages, has been identified, that induces an indomethacin-resistant fever." | 3.70 | Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages. ( de Souza, GE; Hoadley, ME; Hopkins, SJ; Luheshi, G; Rothwell, NJ; Zampronio, AR, 2000) |
"Recently, the carbon monoxide (CO)-heme oxygenase pathway has been shown to play an important role in fever generation by acting on the central nervous system, but the mechanisms involved have not been assessed." | 3.70 | Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way. ( Branco, LG; Steiner, AA, 2000) |
" induced by acetic acid and the fever elicited by baker's yeast." | 3.70 | Antiinflammatory potency of dehydrocurdione, a zedoary-derived sesquiterpene. ( Endo, M; Fujii, E; Hohsho, H; Muraki, T; Shiba, N; Shibuya, H; Tokunaga, Y; Wada, K; Yoshioka, T, 1998) |
" Intraperitoneal pretreatment with the cyclo-oxygenase inhibitor indomethacin (2 mg kg(-1)), which partially reduced LPS-induced fever, did not modify the hyperthermic response to endothelin-1 (3 fmol, i." | 3.70 | Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats. ( D'Orléans-Juste, P; Fabricio, AS; Rae, GA; Silva, CA; Souza, GE, 1998) |
" Indomethacin (IND) has previously been shown to prevent lipopolysaccharide (LPS) fever in prepubertal pigs." | 3.70 | Comparison of the antipyretic actions of indomethacin and L-745,337, a selective cyclooxygenase-2 inhibitor, in endotoxin-treated prepubertal pigs. ( Parrott, RF; Vellucci, SV, 1998) |
"We have studied the mechanism by which interleukin-8 (IL-8) induces fever in rats." | 3.69 | Interleukin-8 induces fever by a prostaglandin-independent mechanism. ( Cunha, FQ; Ferreira, SH; Silva, CA; Souza, GE; Zampronio, AR, 1994) |
"As zymosan-induced arthritis in rats combines dual activation of early prostaglandin-dependent processes (edema, fever, pain) and IL-1 related effects on cartilage metabolism, we compared the respective influences of indomethacin (IMT) and dexamethasone (DEX) on its course." | 3.69 | Zymosan-induced arthritis in rats. II. Effects of anti-inflammatory drugs. ( Gegout, P; Gillet, P; Netter, P; Terlain, B, 1995) |
"The aim of this study was to determine if evolution of fever after administration of indomethacin to febrile patients could separate those with fever of infectious origin from those with non-infectious origin." | 3.69 | [Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?]. ( Barrier, J; Becq-Giraudon, B; Ramassamy, A; Roblot, P, 1995) |
"7 microgram/kg] induce monophasic fever, increase anterior and posterior pituitary hormone release, and enhance hypothalamic c-Fos expression in pigs, all of which can be prevented by indomethacin (Ind)." | 3.69 | Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs. ( Forsling, ML; Goode, JA; Lloyd, DM; Parrott, RF; Vellucci, SV, 1997) |
" Both the fever and the increased circulating levels of IFN, TNF, and IL-2 produced by SEA were decreased by pretreatment with indomethacin (a cyclo-oxygenase inhibitor) (15 mg/kg, intraperitoneally), anisomycin (a protein synthesis inhibitor) (15 mg/kg, subcutaneously), or dexamethasone (an effective anti-inflammatory and immunosuppressive agent) (4 mg/kg, intravenously) in rabbits." | 3.69 | Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits. ( Huang, WT; Lin, MT; Won, SJ, 1997) |
" In rat adjuvant arthritis, NS-398 showed a therapeutic effect comparable to that seen with loxoprofen but less than that seen with indomethacin and diclofenac." | 3.68 | NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. ( Arai, I; Futaki, N; Hamasaka, Y; Higuchi, S; Iizuka, H; Otomo, S; Yoshikawa, K, 1993) |
"To investigate the relation of arachidonate metabolism to the induction of fever by interleukin-1, indomethacin was administered in either an intracerebroventricular (icv) or a subcutaneous (sc) route in conscious rabbits." | 3.68 | Characterization and mechanism of fever induction by interleukin-1 beta. ( Hashimoto, M, 1991) |
" In adjuvant arthritis, E5090 suppressed both the paw swelling and the enhancements of ESR and number of peripheral blood leucocytes, like the steroidal antiinflammatory drug prednisolone." | 3.68 | Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation. ( Chiba, K; Goto, M; Hashida, R; Ono, H; Shirota, H, 1991) |
"These experiments sought to determine the role of arginine vasopressin (AVP) in the inability of newborns to produce a fever." | 3.67 | Vasopressin functions as an endogenous antipyretic in the newborn. ( Kasting, NW; Wilkinson, MF, 1987) |
"Acetylsalicylic acid (300 mg/kg), mefenamic acid (30 mg/kg) or indomethacin (20 mg/kg) given orally in the doses preventing the postpyrogenic fever, inhibited the stimulatory effect of LPS on phagocytic and killing activity of neutrophils." | 3.67 | Inhibition of postpyrogenic increase of phagocytic and killing activity of neutrophils by nonsteroid antiinflammatory drugs. ( Debowy, J; Garbuliński, T; Obmińska-Domoradzka, B; Switała, M, 1988) |
"Effects of indomethacin, a potent inhibitor of prostaglandin (PG) synthesis, on the fever induced by recombinant human interleukin 1-alpha (rhIL 1-alpha) was studied in conscious rabbits." | 3.67 | Effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits. ( Bando, T; Hashimoto, K; Hashimoto, M; Iriki, M, 1988) |
"In the rabbit, intracerebroventricular administration of dibutyryl cyclic AMP (DBC) produces fever which is selectively antagonised by phenoxybenzamine." | 3.66 | Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit. ( Kandasamy, SB, 1980) |
" The effects of indomethacin on fever induced by MDP or its conjugated derivative were studied." | 3.66 | Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide. ( Chedid, L; Dinarello, CA; Parant, F; Parant, M; Riveau, G; Wolff, SM, 1980) |
" This case report and review concerns a patient with Sweet's syndrome in whom dramatic relief of severe arthralgias, myalgias, and painful skin lesions occurred using indomethacin." | 3.65 | Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin. ( Hoffman, GS, 1977) |
" Arachidonate fever was inhibited by intraventricular injection of indomethacin, but not by the simultaneous intraventricular injection of either of the two prostaglandin antagonists SC 19220 or HR 546." | 3.65 | Effects of prostaglandin antagonism on sodium arachidonate fever in rabbits. ( Laburn, H; Mitchell, D; Rosendorff, C, 1977) |
"The simlutaneous oral administration of benorylate (4-(acetamido) phenyl 2-acetoxybenzoate) with either indomethacin or phenylbutazone to rats suffering from Freund's adjuvant-induced arthritis leads to an anti-inflammatory effect which is significantly greater than the effect of the same drugs administered alone." | 3.65 | Benorylate interaction with indomethacin and phenylbutazone. ( Khalili-Varasteh, H; Legros, J; Rosner, I, 1976) |
"The capacity of ibuprofen to reduce fever in children was compared with that of aspirin, paracetamol, aminophenazone and indomethacin." | 3.65 | Oral antipyretic therapy. ( Keinänen, S; Kouvalainen, K; Similä, S, 1976) |
" In a rat paw edema test for anti-inflammatory activity naproxen was 55 times more active than aspirin." | 3.65 | Chemistry and pharmacology of naproxen. ( Dorfman, RI, 1975) |
"Evidence for the effectiveness of ketoprofen in animal models of inflammation and its antipyretic effect is reviewed." | 3.65 | Some pharmacological and toxicological studies on ketoprofen. ( Ducrot, R; Guyonnet, JC; Julou, L; Pasquet, J, 1976) |
"LADG for early gastric cancer is a feasible and safe procedure with short-term clinical results superior to those of ODG." | 2.78 | Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial. ( Bax, L; Futawatari, N; Katada, N; Kikuchi, S; Okutomi, T; Sakuramoto, S; Wang, G; Watanabe, M; Yamashita, K, 2013) |
"Paraneoplastic fever is well known, and is not an uncommon problem in daily practice." | 2.67 | A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever. ( Bacojanis, C; Beldecos, D; Karabelis, A; Karvounis, N; Kosmidis, P; Milonacis, N; Tsavaris, N; Zinelis, A, 1990) |
"Indomethacin was significantly quicker at clearing fever than acetaminophen (P < 0." | 2.67 | Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria. ( Looareesuwan, S; Wilairatana, P, 1994) |
"Fever is frequently a symptom in patients suffering from cancer and in most cases it is related to infections or complications of the treatment." | 2.67 | [Antipyretic effect of indomethacin vs aspirin in fever of tumor origin]. ( Asef, SG; Berbotto, GA; Elias, G; Ostoich, MT; Teglia, O, 1993) |
"Systemic-onset juvenile idiopathic arthritis (SoJIA), sometimes called Still's disease, is a systemic inflammatory disease classified within the spectrum of juvenile idiopathic arthritis (JIA)." | 2.48 | Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease. ( Cimaz, R; Hofer, M; Von Scheven, A, 2012) |
"Juvenile idiopathic arthritis is the most common chronic rheumatic disease of unknown aetiology in childhood and predominantly presents with peripheral arthritis." | 1.46 | Juvenile Idiopathic Arthritis. ( Adrovic, A; Barut, K; Kasapçopur, Ö; Şahin, S, 2017) |
"Morphine-induced fever was not modified by the cyclooxygenase (COX) inhibitor indomethacin (2." | 1.35 | Endogenous opioids: role in prostaglandin-dependent and -independent fever. ( Fernandes, LC; Fraga, D; Machado, RR; Souza, GE; Zampronio, AR, 2008) |
"Exposure to hypoxemia resulted in significant elevation of plasma IL-6 in both untreated and treated with lipopolysaccharide (LPS) mice." | 1.33 | Hypoxia-induced sickness behaviour. ( Kozak, W; Walentynowicz, K; Wrotek, S, 2006) |
"Pre-treatment with indomethacin reduced the fever and adrenocortical activation induced by gp120 administration, but not its behavioral effects." | 1.31 | Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandins. ( Barak, O; Ben-Hur, T; Goshen, I; Taylor, AN; Weidenfeld, J; Yirmiya, R, 2002) |
"Fever was monitored using a rectal probe." | 1.31 | Involvement of CRH in fever induced by a distinct pre-formed pyrogenic factor (PFPF). ( Hopkins, SJ; Melo, MC; Souza, GE; Zampronio, AR, 2000) |
"Indomethacin was a potent inhibitor of both COX-1 (IC50 = 18 +/- 3 nM) and COX-2 (IC50 = 26 +/- 6 nM) under the same assay conditions." | 1.30 | Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. ( Boyce, S; Brideau, C; Chan, CC; Charleson, S; Cromlish, W; Ethier, D; Evans, J; Falgueyret, JP; Ford-Hutchinson, AW; Gordon, R; Greig, G; Gresser, M; Guay, J; Kargman, S; Léger, S; Mancini, JA; O'Neill, G; Ouellet, M; Percival, MD; Riendeau, D; Rodger, IW; Thérien, M; Wang, Z; Webb, JK; Wong, E, 1997) |
"Local inflammation was induced by subcutaneous injection of turpentine (100 microl/mouse)." | 1.30 | Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation. ( Conn, CA; Kluger, MJ; Kozak, W; Rudolph, K; Soszynski, D, 1997) |
"A patient with rheumatoid arthritis is described who presented with low-grade fever for 3 months, in whom Actinobacillus ureae was cultured from bone marrow aspirate." | 1.30 | Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient. ( Avlami, A; Dounis, E; Kordossis, T; Papalambrou, C; Tzivra, M, 1997) |
"Fever was induced by intraperitoneal injection of lipopolysaccharide at doses from 10 micrograms/kg to 2." | 1.30 | Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice. ( Archuleta, I; Kluger, MJ; Kozak, A; Kozak, W; Mayfield, KP; Rudolph, K, 1998) |
"Indomethacin treatment (5 mg/kg subcutaneously) completely abolished these responses." | 1.30 | Polysaccharide mannan components of Candida albicans and Saccharomyces cerevisiae cell wall produce fever by intracerebroventricular injection in rats. ( Akarsu, ES; Ataoğlu, H; Ataoğlu, O; Doğan, MD, 1999) |
"The influence of dosing time on the fever induced by interferon-alpha (IFN-alpha) was investigated in ICR male mice under light-dark cycle." | 1.30 | Circadian rhythm of fever induced by interferon-alpha in mice. ( Higuchi, S; Koyanagi, S; Ohdo, S; Yukawa, E, 1997) |
"Pretreatment with indomethacin, an inhibitor of prostaglandin synthesis, did not affect IL-1 beta production in the brain induced by 4 micrograms kg-1 LPS." | 1.29 | Interleukin-1 beta production in the rabbit brain during endotoxin-induced fever. ( Morimoto, A; Murakami, N; Nakamori, T; Watanabe, T; Yamaguchi, K, 1994) |
"Prolonged fever is an uncommon diagnostic problem in a spinal cord injury patient." | 1.29 | Prolonged fever and heterotopic ossification in a C4 tetraplegic patient. Case report. ( Kong, KH; Tow, AP, 1995) |
"LPS induced thermal and mechanical hyperalgesia which was reversed by i." | 1.29 | Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists. ( Dray, A; Perkins, M; Walker, K, 1996) |
"1." | 1.29 | Nitric oxide synthase-cyclo-oxygenase pathways in organum vasculosum laminae terminalis: possible role in pyrogenic fever in rabbits. ( Lin, JH; Lin, MT, 1996) |
"The indomethacin was well tolerated." | 1.29 | A retrospective analysis of the effect of indomethacin on adverse reactions to orthoclone OKT3 in the therapy of acute renal allograft rejection. ( Burke, JF; Dunn, SR; Francos, BB; Francos, GC; Gaughan, WJ, 1994) |
" MIP-1 induced a biphasic or monophasic fever of short latency characterized by an inverse dose-response curve." | 1.28 | Macrophage inflammatory protein-1: unique action on the hypothalamus to evoke fever. ( Cerami, A; Davatelis, G; Fahey, T; Miñano, FJ; Myers, RD; Paez, X; Sancibrian, M; Sherry, B; Vizcaino, M, 1990) |
"Fever was induced by intravenous injection of lipopolysaccharide (LPS) of E." | 1.28 | Influence of nonsteroid anti-inflammatory drugs on lymphocyte subpopulation and on the primary humoral response in normothermic and feverish rabbits. ( Debowy, J; Garbuliński, T; Obmińska-Domoradzka, B; Switała, M, 1989) |
" After acclimation, rectal temperatures were recorded hourly following five separate ascorbate dosage treatments: 0 (control dosage), 2, 10 or 50 mg ascorbic acid/100 g body wt, or 50 mg ascorbic acid and 0." | 1.28 | Effect of single oral doses of ascorbic acid on body temperature in healthy guinea pigs. ( Johnston, CS, 1989) |
"Fevers were induced by IP EP (1." | 1.27 | Activation of acute-phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs. ( Ahokas, RA; Blatteis, CM; Hunter, WS; Llanos, J; Mashburn, TA, 1984) |
"Indomethacin pretreatment prevented the initial phase of pulmonary hypertension, the increases in thromboxane and prostacyclin metabolites in lung lymph, and the febrile response to toxin infusion but did not modify the granulocytopenia or the increased pulmonary vascular permeability." | 1.27 | Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep. ( Brigham, KL; Larsson, LE; Ogletree, ML; Rojas, J; Stahlman, MT, 1983) |
"Indomethacin was effective in reducing temperature in 10 of 11 cases which showed a dipyrone-resistant hyperthermia developing in the first 24 hours after brain damage, while no significant antipyretic effect was seen in hyperthermic cases developing more than 72 hours after cranial trauma or brain surgery." | 1.27 | Indomethacin is effective against neurogenic hyperthermia following cranial trauma or brain surgery. ( Benedek, G; Colner-Sasi, K; Hortobágyi, A; Janáky, J; Obál, F; Tóth-Daru, P, 1987) |
"Treatment with indomethacin prevented the 1-2 degrees C increase in body temperature observed in septic animals." | 1.27 | Fever is not responsible for the elevated glucose kinetics in sepsis. ( Bagby, GJ; Blakesley, HL; Lang, CH; Spitzer, JJ, 1987) |
"indomethacin were qualitatively similar to i." | 1.27 | The antipyretic effects of centrally administered vasopressin at different ambient temperatures. ( Kasting, NW; Wilkinson, MF, 1987) |
"Biphasic fevers were induced in sheep with intravascular infusions or injections of 4-10 mug (80-200 ng/kg) of endotoxin, whereas monophasic fevers were obtained with doses of 1-2/mug (20-40 ng/kg)." | 1.26 | Role of prostaglandin E in the biphasic fever response to endotoxin. ( Brown, SK; Hull, SS; McCracken, JA; Skarnes, RC, 1981) |
"Indomethacin pretreatment prevented the first part of the febrile response and only a slight temperature rise occurred after a long latency." | 1.26 | Endotoxin fever in the newborn kitten. The role of prostaglandins and monoamines. ( Székely, M, 1979) |
" The very shallow dose-response curves for flurbiprofen compared with acetylsalicylic acid, especially in the mouse and the rat test systems, are not due to an unreliable or abnormal absorption, which suggests that in these species the mode of action of flurbiprofen is not identical with that of acetylsalicylic acid." | 1.25 | Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent. ( Adams, SS; McCullough, KF; Nicholson, JS, 1975) |
" A dose of 10 mug/kg caused a parallel shift to the right of the log dose-response curve for I." | 1.25 | The antipyretic effect of indomethacin. ( Clark, WG; Cumby, HR, 1975) |
"Indomethacin was more potent than paracetamol and both were more potent than injected I." | 1.25 | Prostaglandins, endotoxin and lipid A on body temperature in rats. ( Feldberg, W; Saxena, PN, 1975) |
"Fever was produced by injection of the bacterial pyrogen of Shigella dysenteriae either into the third ventricle, cisterna magna or I." | 1.25 | Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats. ( Feldberg, W; Gupta, KP; Milton, AS; Wendlandt, S, 1973) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 106 (46.49) | 18.7374 |
1990's | 73 (32.02) | 18.2507 |
2000's | 25 (10.96) | 29.6817 |
2010's | 21 (9.21) | 24.3611 |
2020's | 3 (1.32) | 2.80 |
Authors | Studies |
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Terada, A | 1 |
Naruto, S | 1 |
Wachi, K | 1 |
Tanaka, S | 1 |
Iizuka, Y | 2 |
Misaka, E | 1 |
Puig, C | 1 |
Crespo, MI | 1 |
Godessart, N | 1 |
Feixas, J | 1 |
Ibarzo, J | 1 |
Jiménez, JM | 1 |
Soca, L | 1 |
Cardelús, I | 1 |
Heredia, A | 1 |
Miralpeix, M | 1 |
Puig, J | 1 |
Beleta, J | 1 |
Huerta, JM | 1 |
López, M | 1 |
Segarra, V | 1 |
Ryder, H | 1 |
Palacios, JM | 1 |
Uramaru, N | 1 |
Shigematsu, H | 1 |
Toda, A | 1 |
Eyanagi, R | 1 |
Kitamura, S | 1 |
Ohta, S | 1 |
Nascimento, WM | 1 |
Oliveira, JRS | 1 |
Cunha, RX | 1 |
Gambôa, DSR | 1 |
Silva, APS | 1 |
Lima, VLM | 1 |
Mota, CMD | 1 |
Madden, CJ | 1 |
Siddique, S | 1 |
Ahmad, KR | 1 |
Nawaz, SK | 1 |
Ahmad, SN | 1 |
Ali, R | 1 |
Inayat, I | 1 |
Suleman, S | 1 |
Kanwal, MA | 1 |
Usman, M | 1 |
Barut, K | 1 |
Adrovic, A | 1 |
Şahin, S | 1 |
Kasapçopur, Ö | 1 |
Bastos-Pereira, AL | 2 |
Fraga, D | 4 |
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Kluger, MJ | 6 |
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Watanabe, T | 6 |
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Yoshimura, M | 2 |
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Farrant, PJ | 1 |
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McCracken, GH | 1 |
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Shirota, H | 2 |
Chiba, K | 2 |
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Paez, X | 1 |
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Karvounis, N | 1 |
Kosmidis, P | 1 |
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Iwata, M | 1 |
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Debowy, J | 3 |
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Garbuliński, T | 3 |
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Domer, FR | 1 |
Mori, K | 1 |
Sokoloff, L | 1 |
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7 reviews available for indomethacin and Pyrexia
Article | Year |
---|---|
Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Ar | 2012 |
Sweet's syndrome (acute febrile neutrophilic dermatosis).
Topics: Adult; Arthritis; Clofazimine; Diagnosis, Differential; Eye Diseases; Female; Fever; Humans; Indomet | 1982 |
The neurological basis of fever.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Brain; Fever; Humans; Indomethacin; Prostaglandins | 1996 |
Successful treatment of severe cytophagic histiocytic panniculitis with cyclosporine A.
Topics: Adolescent; Adrenal Cortex Hormones; Biopsy; Bone Marrow; Cyclosporine; Female; Fever; Humans; Indom | 1996 |
Brain eicosanoids and LPS fever: species and age differences.
Topics: Age Factors; Animals; Brain Chemistry; Chickens; Cyclooxygenase Inhibitors; Eicosanoids; Fever; Hypo | 1998 |
A critical reappraisal of juvenile rheumatoid arthritis.
Topics: Agammaglobulinemia; Arthritis, Juvenile; Aspirin; Cardiomegaly; Child; Child, Preschool; Chloroquine | 1971 |
Inhibition of prostaglandin biosynthesis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Cats; Cattle; Depression, Chemical; Dogs; Fa | 1974 |
14 trials available for indomethacin and Pyrexia
Article | Year |
---|---|
Laparoscopy versus open distal gastrectomy by expert surgeons for early gastric cancer in Japanese patients: short-term clinical outcomes of a randomized clinical trial.
Topics: Administration, Rectal; Aged; Analgesia, Patient-Controlled; Analgesics; Carcinoma; Comorbidity; Cri | 2013 |
[A clinical study on the effect of K-708 (acemetacin)--a double blind comparative study with ibuprofen in upper respiratory tract inflammation with fever (author's transl)].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blind Method; Femal | 1981 |
Antipyretic efficacy of indomethacin and acetaminophen in uncomplicated falciparum malaria.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Female; Fever; Humans; Indomethacin; Malaria | 1994 |
[Antipyretic effect of indomethacin vs aspirin in fever of tumor origin].
Topics: Aspirin; Body Temperature; Female; Fever; Humans; Indomethacin; Male; Middle Aged; Neoplasms | 1993 |
Reduction of the initial febrile response to OKT3 with indomethacin.
Topics: Acetaminophen; Adult; Creatinine; Diphenhydramine; Drug Administration Schedule; Female; Fever; Graf | 1993 |
Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo.
Topics: Cardiac Surgical Procedures; Clinical Trials as Topic; Cross Infection; Double-Blind Method; Fever; | 1978 |
A randomized trial of the effect of three non-steroid anti-inflammatory agents in ameliorating cancer-induced fever.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female; Fever; Humans; Indomethacin; Male; Napr | 1990 |
Repetitive weekly cycles of interleukin-2. II. Clinical and immunologic effects of dose, schedule, and addition of indomethacin.
Topics: Adult; Aged; Cytotoxicity, Immunologic; Drug Administration Schedule; Female; Fever; Humans; Hypoten | 1988 |
Effects of indomethacin on endocrine responses and nitrogen loss after surgery.
Topics: Blood Glucose; Catecholamines; Female; Fever; Glucagon; Humans; Hydrocortisone; Indomethacin; Male; | 1987 |
Treatment of juvenile rheumatoid arthritis -- a world survey.
Topics: Adrenal Cortex Hormones; Arthritis, Juvenile; Aspirin; Australia; Clinical Trials as Topic; Drug The | 1974 |
A comparative evaluation of indomethacin, acetaminophen and placebo as antipyretic agents in children.
Topics: Acetaminophen; Chemical Phenomena; Chemistry; Child; Clinical Trials as Topic; Fever; Humans; Indome | 1968 |
A controlled clinical trial with indomethacin as an antipyretic in children.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Fever; Humans; Indomethacin; Infant; Placebos; Su | 1969 |
[Antipyretic effects of indomethacin in acute infectious diseases--a double blind test].
Topics: Adolescent; Adult; Aged; Cholecystitis; Colitis; Female; Fever; Humans; Indomethacin; Infections; Ma | 1971 |
Antipyretic effect of indomethacin suppositories: A double-blind study.
Topics: Analgesics; Child; Child, Preschool; Fever; Humans; Indomethacin; Infant; Infant, Newborn; Infection | 1969 |
207 other studies available for indomethacin and Pyrexia
Article | Year |
---|---|
Synthesis and antiinflammatory activity of [(cycloalkylmethyl)phenyl]acetic acids and related compounds.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Female; Fever; Ibuprofen; Indomethacin; Inflamma | 1984 |
Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Cyclooxygenase Inhibitors | 2000 |
Design, synthesis, and pharmacological activity of nonallergenic pyrazolone-type antipyretic analgesics.
Topics: Allergens; Analgesics; Animals; Antipyretics; Body Temperature; Drug Design; Fever; Guinea Pigs; Hyp | 2010 |
Evaluation of the treatment of fever, pain and inflammation with Indigofera suffruticosa Miller Leaves Aqueous Extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Fever; Indigofera; Indomethacin; Inflam | 2022 |
Neural circuits mediating circulating interleukin-1β-evoked fever in the absence of prostaglandin E2 production.
Topics: Adipose Tissue, Brown; Animals; Dinoprostone; Fever; Hypothalamus; Indomethacin; Interleukin-1beta; | 2022 |
Evaluation of the anti-inflammatory, analgesic, anti-pyretic and anti-ulcerogenic potentials of synthetic indole derivatives.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics | 2023 |
Juvenile Idiopathic Arthritis.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; | 2017 |
Central mediators of the zymosan-induced febrile response.
Topics: Animals; Body Temperature; Celecoxib; Dinoprostone; Fever; Indomethacin; Infusions, Intraventricular | 2017 |
Anti-inflammatory and anti-ulcerogenic activities of Chantaleela recipe.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antipyretics; Carrageenan; Dinopro | 2012 |
Dipyrone metabolite 4-MAA induces hypothermia and inhibits PGE2 -dependent and -independent fever while 4-AA only blocks PGE2 -dependent fever.
Topics: Ampyrone; Animals; Antipyretics; Body Temperature; Dinoprostone; Dipyrone; Fever; Hypothalamus; Hypo | 2014 |
Assessment of pharmacological activities of two medicinal plant of Bangladesh: Launaea sarmentosa and Aegialitis rotundifolia roxb in the management of pain, pyrexia and inflammation.
Topics: Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Aspirin; Asteraceae; Ban | 2014 |
Central mediators involved in the febrile response induced by polyinosinic-polycytidylic acid: lack of involvement of endothelins and substance P.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Body Temperature; Celecoxib; Central N | 2015 |
A novel selective prostaglandin E2 synthesis inhibitor relieves pyrexia and arthritis in Guinea pigs inflammatory models.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimen | 2016 |
Evidence of substance P autocrine circuitry that involves TNF-α, IL-6, and PGE2 in endogenous pyrogen-induced fever.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Corticotropin-Releasing Hormone; | 2016 |
Interleukin-1β and interleukin-6 enhance thermal prolongation of the LCR in decerebrate piglets.
Topics: Animals; Animals, Newborn; Body Temperature; Cyclooxygenase Inhibitors; Decerebrate State; Disease M | 2016 |
Female Sex Hormones Influence the Febrile Response Induced by Lipopolysaccharide, Cytokines and Prostaglandins but not by Interleukin-1β in Rats.
Topics: Animals; Body Temperature; Cytokines; Estrogens; Female; Fever; Gonadal Steroid Hormones; Indomethac | 2016 |
Immunomodulatory, analgesic and antipyretic effects of violacein isolated from Chromobacterium violaceum.
Topics: Acetic Acid; Analgesics; Anaphylaxis; Animals; Behavior, Animal; Chromobacterium; Dose-Response Rela | 2010 |
Anti-inflammatory activity of a HPLC-fingerprinted aqueous infusion of aerial part of Bidens tripartita L.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Bidens; Carrageenan; Chromatography, High Pressure Li | 2010 |
Anti-inflammatory and antipyretic effects of Sonchus oleraceus in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cotton Fiber; Disease Models, Animal; Edema; Fever; | 2010 |
Cyclooxygenase-independent mechanism of ibuprofen-induced antipyresis: the role of central vasopressin V₁ receptors.
Topics: Animals; Antipyretics; Arginine Vasopressin; Dinoprostone; Dose-Response Relationship, Drug; Fever; | 2011 |
The antipyretic effect of dipyrone is unrelated to inhibition of PGE(2) synthesis in the hypothalamus.
Topics: Animals; Antipyretics; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Dipyrone; Endothel | 2011 |
Ccl22/MDC, is a prostaglandin dependent pyrogen, acting in the anterior hypothalamus to induce hyperthermia via activation of brown adipose tissue.
Topics: Adipose Tissue, Brown; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Chemokine | 2011 |
Indomethacin abolishes core temperature, but not cardiovascular or renal, responses to lipopolysaccharide in conscious lambs.
Topics: Animals; Blood Pressure; Body Temperature; Cardiovascular Agents; Cardiovascular System; Consciousne | 2011 |
Protective role of indomethacin on lipopolysaccharide-stimulated fever induction and cerebral catecholamine biosynthesis in Wistar rat.
Topics: Acute-Phase Reaction; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain; Dop | 2012 |
Indomethacin impairs LPS-induced behavioral fever in toads.
Topics: Animals; Behavior, Animal; Body Temperature Regulation; Bufonidae; Cyclooxygenase Inhibitors; Female | 2002 |
Polyarteritis nodosa.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclophosphamide; Diagnostic Errors; Fever; Glucocor | 2002 |
Intracerebral HIV-1 glycoprotein 120 produces sickness behavior and pituitary-adrenal activation in rats: role of prostaglandins.
Topics: Adrenocorticotropic Hormone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cor | 2002 |
Central tumour necrosis factor-alpha mediates the early gastrointestinal motor disturbances induced by lipopolysaccharide in sheep.
Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Female; Fever; Gastrointestinal Motility; Huma | 2003 |
THE EFFECT OF PYREXIA ON RAT GASTRIC SECRETION.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Body Temperature; Fever; Gastric Juice; Hot Temp | 1964 |
Role of prostaglandin E2 and indomethacin in the febrile response of pigeons.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Columbidae; Dinoprostone; Escherichia coli; Fever; | 2003 |
Involvement of eicosanoids in the hypothermic response to lipopolysaccharide during endotoxemia in rats.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Eicosanoids; Endotoxemia; Fever; Hypoth | 2004 |
[Fever and arthritis in a 36 year-old woman].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Viral; Arthritis; Female; Fever; Humans; | 2004 |
Interleukin (IL)-6, but not IL-1, induction in the brain downstream of cyclooxygenase-2 is essential for the induction of febrile response against peripheral IL-1alpha.
Topics: Animals; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Female; Fe | 2004 |
Indomethacin attenuates hyperthermia produced by anterior coronal lateral hypothalamic knife cuts.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Brain Injuries; Fever; Hypothala | 2004 |
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Dinoprost; Dinoprostone; Dose-Response Re | 2005 |
Anti-inflammatory, anti-nociceptive and antipyretic effects of extracts of Phrygilanthus acutifolius flowers.
Topics: Acetic Acid; Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non- | 2006 |
Nimesulide-induced antipyresis in rats involves both cyclooxygenase-dependent and independent mechanisms.
Topics: Analgesics, Non-Narcotic; Animals; Arachidonic Acid; Body Temperature; Chemokine CCL3; Chemokine CCL | 2006 |
CCL3/macrophage inflammatory protein-1alpha induces fever and increases prostaglandin E2 in cerebrospinal fluid of rats: effect of antipyretic drugs.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Body Temperature; Body Temperature Regulati | 2006 |
Hypoxia-induced sickness behaviour.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Dinoprostone; Eating; Fever; Hypoxia; Indo | 2006 |
Role of prostaglandins in heme-induced fever.
Topics: Animals; Body Temperature; Brain; Dinoprostone; Dose-Response Relationship, Drug; Fever; Heme; Immun | 2006 |
Action of cyclooxygenase inhibitors and a leukotriene biosynthesis inhibitor on cisplatin-induced acute and delayed emesis in the ferret.
Topics: Animals; Antineoplastic Agents; Cisplatin; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; D | 2007 |
Endogenous opioids: role in prostaglandin-dependent and -independent fever.
Topics: Analgesics, Opioid; Animals; Cyclooxygenase Inhibitors; Fever; Indomethacin; Lipopolysaccharides; Ma | 2008 |
Effects of intracerebroventricular floctafenine and indomethacin on body temperature in febrile rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Female; Fever; In Vitro Techniqu | 1980 |
Increased intraocular pressure and hyperthermia following administration of substance P into rabbit third ventricle.
Topics: Acetazolamide; Animals; Aqueous Humor; Body Temperature; Dose-Response Relationship, Drug; Fever; In | 1982 |
Central effect of dibutyryl cyclic AMP on the temperature in the conscious rabbit.
Topics: Animals; Body Temperature; Brain; Bucladesine; Cyproheptadine; Drug Interactions; Fever; Hydroxydopa | 1980 |
Central versus peripheral sites of antipyretic action of a non-steroidal anti-inflammatory agent, AD-1590, in rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Catecholamines; Dibenzoxepins; Dinoprostone | 1984 |
Relationship of trace metals to fever during infection: are prostaglandins involved?
Topics: Animals; Body Temperature; Endotoxins; Escherichia coli; Fever; Indomethacin; Male; Pasteurella Infe | 1983 |
Stimulation of muscle protein degradation and prostaglandin E2 release by leukocytic pyrogen (interleukin-1). A mechanism for the increased degradation of muscle proteins during fever.
Topics: Animals; Body Temperature; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Humans; In Vitro Techniqu | 1983 |
Effects of cyclooxygenase inhibition on the response to group B streptococcal toxin in sheep.
Topics: Animals; Bacterial Toxins; Capillary Permeability; Cyclooxygenase Inhibitors; Fever; Granulocytes; H | 1983 |
Activation of acute-phase responses by intrapreoptic injections of endogenous pyrogen in guinea pigs.
Topics: Animals; Body Temperature; Dinoprostone; Fever; Guinea Pigs; Indomethacin; Interleukin-1; Leukocytes | 1984 |
Comparative effects of indoprofen and indomethacin on rat hypothalamic prostaglandin-synthetase activity.
Topics: Animals; Cyclooxygenase Inhibitors; Fever; Hypothalamus; Indomethacin; Indoprofen; Phenylpropionates | 1981 |
Effects of cloned interferon alpha 2 in normal volunteers: febrile reactions and changes in circulating corticosteroids and trace metals.
Topics: 11-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adult; Female; Fever; Humans; Indomethacin; Inte | 1983 |
Hyperthermic responses to central injections of some peptide and non-peptide opioids in the guinea-pig.
Topics: Animals; Body Temperature; Endorphins; Fever; Guinea Pigs; Indomethacin; Iodipamide; Naloxone; Narco | 1983 |
Influence of indomethacin on various immunopharmacological effects of muramyl dipeptide (MDP).
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Cattle; Cycloheximide; Fever; Glycopeptides; Guinea Pigs | 1980 |
[Efficacy of indomethacin in neoplastic fever].
Topics: Adult; Female; Fever; Humans; Indomethacin; Neoplasms | 1982 |
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 17-1982. Fever and subcutaneous masses in an elderly man.
Topics: Adipose Tissue; Aged; Diagnosis, Differential; Fever; Humans; Indomethacin; Male; Panniculitis, Nodu | 1982 |
Antipyretic effects of indomethacin in liver metastases of solid tumors.
Topics: Drug Administration Schedule; Female; Fever; Humans; Indomethacin; Liver Neoplasms; Male; Middle Age | 1982 |
Control of fever associated with visceral cancers by indomethacin.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas | 1981 |
Role of prostaglandin E in the biphasic fever response to endotoxin.
Topics: Animals; Blood Pressure; Body Temperature; Carotid Arteries; Endotoxins; Female; Fever; Indomethacin | 1981 |
Effect of indomethacin on increased resistance to bacterial infection and on febrile responses induced by muramyl dipeptide.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Drug Synergism; Fever; Glycopeptides; Immunity, Innate; | 1980 |
[Is the indomethacin test able to indicate the etiological diagnosis of isolated fever?].
Topics: Adult; Aged; Aged, 80 and over; Body Temperature; Diagnosis, Differential; Female; Fever; Humans; Hy | 1995 |
Cyclic haemopoiesis at 7- or 8-day intervals.
Topics: Adult; Anemia; C-Reactive Protein; Erythropoietin; Female; Fever; Granulocyte Colony-Stimulating Fac | 1994 |
Neuromodulation of fever. A possible role for substance P.
Topics: Animals; Fever; Guinea Pigs; Indomethacin; Interleukin 1 Receptor Antagonist Protein; Lipopolysaccha | 1994 |
Fever and the acute elevation in whole-body thermogenesis induced by lateral hypothalamic lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature Regulation; Body Weight; Energy M | 1995 |
Cyclo-oxygenase mediation of endotoxin-induced fever, anterior and posterior pituitary hormone release, and hypothalamic c-Fos expression in the prepubertal pig.
Topics: Animals; Body Temperature; Endotoxins; Fever; Hormones; Hypothalamus; Indomethacin; Lipopolysacchari | 1995 |
Restraint, but not frustration, induces prostaglandin-mediated hyperthermia in pigs.
Topics: Animals; Body Temperature; Fever; Food Deprivation; Frustration; Hydrocortisone; Indomethacin; Prost | 1995 |
Zymosan-induced arthritis in rats. II. Effects of anti-inflammatory drugs.
Topics: Animals; Arthritis; Cartilage, Articular; Dexamethasone; Edema; Fever; Indomethacin; Knee Joint; Mal | 1995 |
Changes in plasma catecholamines during fever induced by bacterial endotoxin and interleukin-1 beta.
Topics: Animals; Catecholamines; Endotoxins; Epinephrine; Fever; Indomethacin; Interleukin-1; Lipopolysaccha | 1994 |
Prolonged fever and heterotopic ossification in a C4 tetraplegic patient. Case report.
Topics: Adult; Fever; Hip; Humans; Indomethacin; Leukocyte Count; Magnetic Resonance Imaging; Male; Ossifica | 1995 |
Fever produced by interleukin-11 (IL-11) injected into the anterior hypothalamic pre-optic area of the rat is antagonized by indomethacin.
Topics: Animals; Body Temperature; Body Weight; Eating; Fever; Humans; Indomethacin; Interleukin-11; Male; M | 1994 |
S14080, a peripheral analgesic acting by release of an endogenous circulating opioid-like substance.
Topics: Adrenalectomy; Analgesics; Animals; Arginine; Dipyrone; Drug Tolerance; Edema; Endorphins; Fever; Hy | 1995 |
Elevation of plasma ACTH concentration in rabbits made febrile by systemic injection of bacterial endotoxin.
Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Corticotropin-Releasing Hormone; Dinoproston | 1994 |
Interleukin-1 beta production in the rabbit brain during endotoxin-induced fever.
Topics: Animals; Bacterial Toxins; Brain Chemistry; Cerebral Ventricles; Endotoxins; Fever; Immunohistochemi | 1994 |
A retrospective analysis of the effect of indomethacin on adverse reactions to orthoclone OKT3 in the therapy of acute renal allograft rejection.
Topics: Acute Disease; Adult; Female; Fever; Graft Rejection; Humans; Indomethacin; Kidney Transplantation; | 1994 |
Interleukin-8 induces fever by a prostaglandin-independent mechanism.
Topics: Animals; Body Temperature; Body Temperature Regulation; Cerebral Ventricles; Dexamethasone; Fever; H | 1994 |
Lipopolysaccharide induces fever and depresses locomotor activity in unrestrained mice.
Topics: Animals; Body Temperature; Body Weight; Feeding Behavior; Fever; Indomethacin; Lipopolysaccharides; | 1994 |
Vasopressin release within the ventral septal area of the rat brain during drug-induced antipyresis.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Fever; Indome | 1993 |
Dexamethasone inhibits the pyrogenic activity of prostaglandin F2 alpha, but not prostaglandin E2.
Topics: Animals; Body Temperature; Dexamethasone; Dinoprost; Dinoprostone; Fever; Indomethacin; Injections, | 1993 |
NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Carrageenan; Cyclooxygena | 1993 |
Prostaglandin-dependent c-Fos expression in the median preoptic nucleus of pigs subjected to restraint: correlation with hyperthermia.
Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Fever; Gene Expression Regulation; | 1995 |
Indomethacin blocks the febrile response induced by interleukin-8 in rabbits.
Topics: Animals; Cyclooxygenase Inhibitors; Fever; Humans; Indomethacin; Injections, Intravenous; Injections | 1995 |
Development of hyperthermia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Fever; Indomethacin; Injections, Intraventricu | 1996 |
Nitric oxide synthase-cyclo-oxygenase pathways in organum vasculosum laminae terminalis: possible role in pyrogenic fever in rabbits.
Topics: Animals; Body Temperature Regulation; Cyclic GMP; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme In | 1996 |
A case of adult onset Still's disease presenting with fever and a rash.
Topics: Adult; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; F | 1996 |
Development of hyperthermia and hyperalgesia following intracerebroventricular administration of endotoxin in the rat: effect of kinin B1 and B2 receptor antagonists.
Topics: Animals; Bradykinin; Bradykinin Receptor Antagonists; Fever; Hyperalgesia; Indomethacin; Inflammatio | 1996 |
Indomethacin attenuation of radiation-induced hyperthermia does not modify radiation-induced motor hypoactivity.
Topics: Animals; Body Temperature Regulation; Cyclooxygenase Inhibitors; Fever; Indomethacin; Male; Motor Ac | 1996 |
Role of central interleukin-1 beta in gastrointestinal motor disturbances induced by lipopolysaccharide in sheep.
Topics: Animals; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Escherichia coli; Female; Fever | 1997 |
Effect of pre-induction of heat shock proteins on indomethacin-induced small-intestinal lesion in rats.
Topics: Animals; Fever; Heat-Shock Proteins; Indomethacin; Intestine, Small; Male; Rats; Rats, Sprague-Dawle | 1997 |
Role of substance P (SP) in the mediation of endotoxin (LPS) fever in rats.
Topics: Alprostadil; Animals; Female; Fever; Indomethacin; Injections, Intraventricular; Lipopolysaccharides | 1997 |
Hypothalamic prostaglandin E2 during lipopolysaccharide-induced fever in guinea pigs.
Topics: Animals; Blood-Brain Barrier; Cyclooxygenase Inhibitors; Dinoprostone; Fever; Guinea Pigs; Hypothala | 1996 |
Dietary n-3 fatty acids differentially affect sickness behavior in mice during local and systemic inflammation.
Topics: Animals; Anorexia; Behavior, Animal; Body Temperature; Body Weight; Cachexia; Coconut Oil; Fatty Aci | 1997 |
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; CHO Cells; Cricetinae; Cyclo | 1997 |
Staphylococcal enterotoxin A-induced fever is associated with increased circulating levels of cytokines in rabbits.
Topics: Animals; Anisomycin; Anti-Inflammatory Agents; Body Temperature; Dexamethasone; Enterotoxins; Fever; | 1997 |
Circadian rhythm of fever induced by interferon-alpha in mice.
Topics: Analgesics, Non-Narcotic; Animals; Circadian Rhythm; Fever; Indomethacin; Interferon-alpha; Male; Mi | 1997 |
Interrelated adrenocortical and neurohypophysial responses associated with fever in endotoxin-treated pigs.
Topics: Analgesics, Non-Narcotic; Animals; Body Temperature Regulation; Dexamethasone; Endotoxins; Escherich | 1997 |
From indomethacin to a selective COX-2 inhibitor. Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Chromium Radioisotopes; Cyclooxygenas | 1997 |
Extracts of rhinoceros horn are not antipyretic in rabbits.
Topics: Analgesics, Non-Narcotic; Animals; Female; Fever; Horns; Indomethacin; Male; Medicine, Chinese Tradi | 1997 |
A role for gastrointestinal endotoxins in enhancement of heat tolerance by physical fitness.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Endotoxins; Fever; Hemodynamics; | 1998 |
Comparison of the antipyretic actions of indomethacin and L-745,337, a selective cyclooxygenase-2 inhibitor, in endotoxin-treated prepubertal pigs.
Topics: Analgesics, Non-Narcotic; Animals; Body Temperature; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; | 1998 |
Bone marrow infection caused by Actinobacillus ureae in a rheumatoid arthritis patient.
Topics: Actinobacillus; Actinobacillus Infections; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, | 1997 |
Anti-inflammatory, analgesic and anti-pyretic effects of d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), a new non-steroidal anti-inflammatory drug, in rats and guinea pigs.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1998 |
Neoplastic fever: choice of antipyrogenic therapy makes a difference.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Carcinoma, Squamous Cell; Fever; Humans; Indomethacin | 1998 |
Inhibitors of alternative pathways of arachidonate metabolism differentially affect fever in mice.
Topics: Animals; Antioxidants; Arachidonic Acid; Body Temperature; Body Temperature Regulation; Clotrimazole | 1998 |
Essential role for endothelin ET(B) receptors in fever induced by LPS (E. coli) in rats.
Topics: Animals; Endothelin Receptor Antagonists; Escherichia coli; Fever; Indomethacin; Injections, Intrave | 1998 |
Antiinflammatory potency of dehydrocurdione, a zedoary-derived sesquiterpene.
Topics: Acetic Acid; Analgesics; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents; Arthritis, Exp | 1998 |
Effect of indomethacin on hyperthermia induced by heat stress in broiler chickens.
Topics: Animals; Body Temperature; Chickens; Cyclooxygenase Inhibitors; Fever; Heat Stress Disorders; Indome | 1998 |
Polysaccharide mannan components of Candida albicans and Saccharomyces cerevisiae cell wall produce fever by intracerebroventricular injection in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Candida albicans; Cytokines; Fev | 1999 |
Role of centrally administered melatonin and inhibitors of COX and NOS in LPS-induced hyperthermia and adipsia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cyclooxygenase Inhibitors; Dinop | 1999 |
Cardiorespiratory responses to interleukin-1beta in adult rats: role of nitric oxide, eicosanoids and glucocorticoids.
Topics: Animals; Blood Pressure; Body Temperature; Cyclooxygenase Inhibitors; Dexamethasone; Eicosanoids; En | 1999 |
Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way.
Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclooxygenase Inhibitors; Deute | 2000 |
Endotoxaemia does not limit heat tolerance in rats: the role of plasma lipoproteins.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Body Temperature; Brain; Endotox | 2000 |
Involvement of CRH in fever induced by a distinct pre-formed pyrogenic factor (PFPF).
Topics: Animals; Chemokine CCL4; Corticotropin-Releasing Hormone; Fever; Indomethacin; Interleukin-8; Macrop | 2000 |
Interleukin (IL)-6 release and fever induced by a pre-formed pyrogenic factor (PFPF) derived from LPS-stimulated macrophages.
Topics: Animals; Cells, Cultured; Cytokines; Fever; Indomethacin; Interleukin-6; Isoelectric Focusing; Lipop | 2000 |
Anti-lymphoma effect of naproxen and indomethacin in a patient with relapsed diffuse large B-cell lymphoma.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Fever; Humans; Indomethacin; Lymph Nodes; Lymphoma, B | 2001 |
Analgesic and antipyretic activities of Rumex patientia extract on mice and rabbits.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Aspirin; Fever; Formaldehyde; Indomethacin; L | 2001 |
Differential inhibition by nimesulide of the early and late phases of intravenous- and intracerebroventricular-LPS-induced fever in guinea pigs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood-Brain Barrier; Brain; Cyclooxygenase 1; Cycl | 2001 |
Benorylate interaction with indomethacin and phenylbutazone.
Topics: Animals; Arthritis; Aspirin; Drug Interactions; Drug Synergism; Fever; Indomethacin; Male; Phenylbut | 1976 |
Effects of prostaglandin antagonism on sodium arachidonate fever in rabbits.
Topics: Animals; Arachidonic Acids; Body Temperature; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-c | 1977 |
Endotoxin fever in the new-born guinea-pig and the modulating effects of indomethacin and p-chlorophenylalanine.
Topics: Animals; Animals, Newborn; Body Temperature; Endotoxins; Escherichia coli; Fenclonine; Fever; Guinea | 1978 |
Endotoxin fever in the newborn kitten. The role of prostaglandins and monoamines.
Topics: Animals; Body Temperature; Cats; Endotoxins; Escherichia coli; Fenclonine; Fever; Indomethacin; Nore | 1979 |
Effect of antipyretics on group A streptococcal pyrogenic exotoxin fever production and ability to enhance lethal endotoxin shock.
Topics: Animals; Aspirin; Cortisone; Drug Synergism; Endotoxins; Exotoxins; Fever; Indomethacin; Prostagland | 1978 |
Role of prostaglandins in mediation of pyrogen fever.
Topics: Animals; Fever; Indomethacin; Methysergide; Prostaglandins E; Rabbits; Rats; Stomach; Typhoid-Paraty | 1979 |
Increase in body temperature during carrageenin-induced paw oedema in the rat. Effect of non-steroid anti-inflammatory substances and essential fatty acid deficiency.
Topics: Acetaminophen; Aging; Animals; Anti-Inflammatory Agents; Brain Chemistry; Carrageenan; Edema; Fatty | 1979 |
Central effect of 5,8,11,14-eicosatetraenoic acid (arachidonic acid) on the temperature in the conscious rabbit.
Topics: Animals; Arachidonic Acids; Body Temperature; Cyproheptadine; Fever; Hydroxydopamines; Indomethacin; | 1977 |
Antagonism by indomethacin of neurogenic hyperthermia produced by unilateral puncture of the anterior hypothalamic/preoptic region.
Topics: Animals; Body Temperature; Dose-Response Relationship, Drug; Fever; Hypothalamus; Hypothalamus, Ante | 1977 |
A primate model for the study of human fever.
Topics: Animals; Body Temperature; Circadian Rhythm; Disease Models, Animal; Dose-Response Relationship, Dru | 1975 |
Postoperative fever in patients with hematologic malignancy.
Topics: Adult; Aged; Colonic Neoplasms; Female; Fever; Humans; Indomethacin; Leukemia; Male; Neoplasms, Mult | 1977 |
Treatment of Sweet's syndrome (active febrile neutrophilic dermatosis) with indomethacin.
Topics: Drug Evaluation; Fever; Humans; Indomethacin; Joint Diseases; Male; Middle Aged; Muscular Diseases; | 1977 |
Oral antipyretic therapy.
Topics: Acetaminophen; Administration, Oral; Aminopyrine; Aspirin; Child; Child, Preschool; Drug Evaluation; | 1976 |
Antagonism by antipyretics of the hyperthermic effect of a prostaglandin precursor, sodium arachidonate, in the cat.
Topics: Acetaminophen; Analgesics; Animals; Arachidonic Acids; Body Temperature; Cats; Fever; Indomethacin; | 1976 |
Some pharmacological and toxicological studies on ketoprofen.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Aspirin; Benzophenones; Fever; Guinea Pigs; Indometha | 1976 |
[Modification of experimental etiocholanolone fever through indomethacin].
Topics: Adult; Etiocholanolone; Fever; Humans; Indomethacin | 1976 |
Some biological properties of flurbiprofen, an anti-inflammatory, analgesic and antipyretic agent.
Topics: Adrenalectomy; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Cap | 1975 |
[Etiocholanolone fever].
Topics: Adult; Diagnosis, Differential; Etiocholanolone; Female; Fever; Fever of Unknown Origin; Humans; Ind | 1975 |
The antipyretic effect of indomethacin.
Topics: Animals; Body Temperature; Brain; Cats; Cerebral Ventricles; Dose-Response Relationship, Drug; Fever | 1975 |
Chemistry and pharmacology of naproxen.
Topics: Administration, Oral; Adrenalectomy; Animals; Aspirin; Carrageenan; Drug Evaluation, Preclinical; Ed | 1975 |
Prostaglandins, endotoxin and lipid A on body temperature in rats.
Topics: Acetaminophen; Animals; Body Temperature; Cerebral Ventricles; Endotoxins; Female; Fever; Indomethac | 1975 |
The antipyretic effect of suprofen in rats with yeast-induced fever.
Topics: Analgesics; Animals; Aspirin; Body Temperature; Dose-Response Relationship, Drug; Drug Evaluation, P | 1975 |
Effects of interleukin-1 beta on blood pressure, sympathetic nerve activity, and pituitary endocrine functions in anesthetized rats.
Topics: Adrenocorticotropic Hormone; Animals; Arginine Vasopressin; Blood Pressure; Dose-Response Relationsh | 1992 |
Indomethacin and sodium carbonate effects on conditioned fever and NK cell activity.
Topics: Animals; Body Temperature; Carbonates; Conditioning, Psychological; Female; Fever; Indomethacin; Kil | 1992 |
Quantitative aspects of the fever response elicited by intracerebral injection of endotoxin in the guinea-pig.
Topics: Analysis of Variance; Animals; Endotoxins; Fever; Guinea Pigs; Indomethacin; Injections; Lipopolysac | 1992 |
Characteristics of TNF alpha- and TNF beta-induced fever in the rabbit.
Topics: Animals; Body Temperature; Fever; Indomethacin; Injections, Intravenous; Injections, Intraventricula | 1992 |
The fever induced by polyriboinosinic:polyribocytidylic acid is not related to interferon synthesis in the rabbit's hypothalamus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Temperature; Cells, Cultured; Cycloheximide; | 1991 |
The effect of indomethacin on the febrile response following OKT3 therapy.
Topics: Adolescent; Adult; Creatinine; Drug Therapy, Combination; Female; Fever; Graft Rejection; Humans; In | 1992 |
Characterization and mechanism of fever induction by interleukin-1 beta.
Topics: Animals; Arachidonic Acid; Dose-Response Relationship, Drug; Fever; Humans; Indomethacin; Injections | 1991 |
Leukotrienes in cerebrospinal fluid of the conscious cat: effect of platelet-activating factor and pyrogens.
Topics: Animals; Cats; Diterpenes; Endotoxins; Fever; Ginkgolides; Indomethacin; Interleukin-1; Lactones; Le | 1991 |
Hypothalamic indomethacin fails to block fever induced in rats by central macrophage inflammatory protein-1 (MIP-1).
Topics: Animals; Body Temperature Regulation; Chemokine CCL4; Cytokines; Electrophoresis, Polyacrylamide Gel | 1991 |
Neuromodulation of fever: apparent involvement of opioids.
Topics: Animals; Fever; Guinea Pigs; Indomethacin; Interleukin-6; Lipopolysaccharides; Male; Naloxone; Tumor | 1991 |
Indomethacin suppositories for pyrexia in children.
Topics: Child; Fever; Humans; Indomethacin; Suppositories | 1991 |
Temperature-dependent modulation of lipopolysaccharide-induced interleukin-1 beta and tumor necrosis factor alpha expression in cultured human astroglial cells by dexamethasone and indomethacin.
Topics: Astrocytes; Cells, Cultured; Dexamethasone; Fever; Humans; Indomethacin; Interleukin-1; Lipopolysacc | 1991 |
Antiinflammatory properties of E5090, a novel orally active inhibitor of IL-1 generation.
Topics: Acrylates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Collagen; Edem | 1991 |
Macrophage inflammatory protein-1: unique action on the hypothalamus to evoke fever.
Topics: Animals; Chemotactic Factors; Fever; Hypothalamus; Indomethacin; Interleukin-8; Male; Prostaglandins | 1990 |
Central action sites of interleukin-1 beta for inducing fever in rabbits.
Topics: Animals; Blood-Brain Barrier; Brain; Fever; Indomethacin; Injections, Intravenous; Injections, Intra | 1990 |
Role of interleukin 6 in fever in rats.
Topics: Animals; Body Temperature; Cerebral Ventricles; Fever; Indomethacin; Injections, Intraperitoneal; In | 1990 |
Suppression of tumor necrosis factor alpha production by a human immunoglobulin preparation for intravenous use.
Topics: Animals; Dinoprostone; Fever; Gene Expression; Immunoglobulins; Indomethacin; Infusions, Intravenous | 1990 |
Influence of nonsteroid anti-inflammatory drugs on lymphocyte subpopulation and on the primary humoral response in normothermic and feverish rabbits.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Dose-Response Relatio | 1989 |
Activation of ACTH release is mediated by the same molecule as the final mediator, PGE2, of febrile response in rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticotropin-Releasing Hormone; Dinoprostone; Dose-Response R | 1989 |
Possible involvement of prostaglandin E in development of ACTH response in rats induced by human recombinant interleukin-1.
Topics: Adrenocorticotropic Hormone; Animals; Body Temperature; Dinoprostone; Dose-Response Relationship, Dr | 1989 |
Neurogenic hyperthermia in subarachnoid hemorrhage.
Topics: Adult; Combined Modality Therapy; Cyproheptadine; Fever; Humans; Indomethacin; Ischemic Attack, Tran | 1989 |
Adult Still's disease: a missed diagnosis.
Topics: Adult; Arthritis, Gouty; Arthritis, Juvenile; Female; Fever; Humans; Indomethacin; Male; Naproxen | 1989 |
Prostaglandin formation in the hypothalamus in vivo: effect of pyrogens.
Topics: Animals; Body Temperature; Cats; Dinoprostone; Endotoxins; Female; Fever; Hypothalamus; Indomethacin | 1989 |
Central vasopressin V1-receptors mediate indomethacin-induced antipyresis in rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Temperature; Brain; Fev | 1989 |
The pathogenesis of cianidanol-induced fever.
Topics: Catechin; Cyclic AMP; Cyclic GMP; Dinoprostone; Fever; Humans; Indomethacin; Interleukin-1; Macropha | 1988 |
Effect of single oral doses of ascorbic acid on body temperature in healthy guinea pigs.
Topics: Animals; Ascorbic Acid; Body Temperature; Fever; Guinea Pigs; Indomethacin; Male; Prostaglandins | 1989 |
Indomethacin is effective against neurogenic hyperthermia following cranial trauma or brain surgery.
Topics: Body Temperature; Brain; Brain Injuries; Dipyrone; Drug Resistance; Fever; Humans; Indomethacin; Pos | 1987 |
Fever is not responsible for the elevated glucose kinetics in sepsis.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Glucose; Blood Pressure; Cyclooxygenase Inhibito | 1987 |
Hyperthermia increases cerebral metabolic rate and blood flow in neonatal pigs.
Topics: Animals; Animals, Newborn; Blood Pressure; Brain; Carbon Dioxide; Cerebrovascular Circulation; Energ | 1988 |
Inhibition of postpyrogenic increase of phagocytic and killing activity of neutrophils by nonsteroid antiinflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Dose-Response Relationship, Drug; Fever; | 1988 |
Effects of leukocytic pyrogen (interleukin-1) on local cerebral glucose utilization in rats with and without premedication with indomethacin or dexamethasone.
Topics: Animals; Body Temperature; Brain; Dexamethasone; Fever; Glucose; Indomethacin; Interleukin-1; Male; | 1988 |
Effect of indomethacin on febrile response to recombinant human interleukin 1-alpha in rabbits.
Topics: Animals; Body Temperature; Cerebral Ventricles; Dose-Response Relationship, Drug; Fever; Indomethaci | 1988 |
Vasopressor responses and hyperthermia by intracerebroventricular injections of penicillin, a pyrogen, in rats: involvement of brain angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Brain; Consciousness; Desoxycorticosterone; Drinking; Fever | 1988 |
Effect of different treatments of the endotoxin-induced modifications in serum iron levels.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Endotoxins; Female; Fever; Indomethacin; Iron; Ket | 1986 |
Vasopressin functions as an endogenous antipyretic in the newborn.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Tempe | 1987 |
The antipyretic effects of centrally administered vasopressin at different ambient temperatures.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine Vasopressin; Body Temperature; Brain; Fev | 1987 |
Pharmacological activity and toxicity of apyramide: comparison with non-steroidal anti-inflammatory agents.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; | 1987 |
Pharmacological properties of N-methoxy-3-(3,5-ditert-butyl-4-hydroxybenzylidene)-2-pyrrolidone (E-5110), a novel nonsteroidal antiinflammatory agent.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Fever; Indomethacin; Inflammation; Pain; Piroxicam | 1987 |
Fever induced in rabbits by intraventricular injection of rabbit and human serum albumin.
Topics: Animals; Blood Cell Count; Body Temperature; Dinoprostone; Dose-Response Relationship, Drug; Fever; | 1987 |
Further evidence that stress hyperthermia is a fever.
Topics: Animals; Body Temperature; Fever; Indomethacin; Injections, Intraperitoneal; Injections, Intraventri | 1987 |
Migration of isolated rabbit lymphocytes in the course of pharmacological inhibition of pyrogenic fever.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cell Movement; Escherichia coli; Fever; Indomethacin; In | 1985 |
Familial nephropathic amyloidosis associated with indomethacin responsive fever.
Topics: Amyloidosis; Female; Fever; Genes, Dominant; Humans; Indomethacin; Kidney Diseases; Middle Aged | 1985 |
Differences in endogenous pyrogen fevers induced by iv and icv routes in rabbits.
Topics: Animals; Fever; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Interleukin-1; | 1985 |
[Action of indomethacin on fever in cancer patients].
Topics: Adolescent; Adult; Aged; Female; Fever; Humans; Indomethacin; Infections; Male; Middle Aged; Neoplas | 1971 |
Aspirin-like drugs and prostaglandins.
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Dogs; Fever; Humans; Indomethacin; Injections, Spinal; P | 1971 |
Symptomatic control of fever in lymphoma and leukemia.
Topics: Adolescent; Adult; Aged; Aminopyrine; Analgesics; Aspirin; Female; Fever; Hodgkin Disease; Humans; I | 1969 |
Further studies on the role of prostaglandin in fever.
Topics: Acetaminophen; Animals; Body Temperature; Calcium; Cats; Cerebral Ventricles; Cerebrospinal Fluid; C | 1974 |
The hyperthermic effect of intracerebroventricular cholera enterotoxin in the unanaesthetized cat.
Topics: Acetaminophen; Animals; Body Temperature; Bucladesine; Cats; Cerebral Ventricles; Consciousness; Cyc | 1974 |
Proceedings: Lipid A and prostaglandin.
Topics: Acetaminophen; Animals; Aspirin; Cats; Endotoxins; Fever; Indomethacin; Lipids; Prostaglandins | 1974 |
Carrageenin hyperthermia in rats.
Topics: Animals; Aspirin; Body Temperature; Carrageenan; Dose-Response Relationship, Drug; Edema; Female; Fe | 1974 |
Antiinflammatory activity and other pharmacological properties of phthalazino(2,3-b)phthalazine-5,12(7H, 14H)-dione (Diftalone).
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Pressure; Diuresis; Drug Ev | 1974 |
Use of Indomethacin as an anti-pyretic agent in malignant reticulosis.
Topics: Adolescent; Adult; Child; Evaluation Studies as Topic; Female; Fever; Hodgkin Disease; Humans; Indom | 1972 |
Effect of pyrogen and antipyretics on prostaglandin acitvity in cisternal c.s.f. of unanaesthetized cats.
Topics: Acetaminophen; Animals; Aspirin; Body Temperature; Cats; Cerebral Ventricles; Chromatography, Thin L | 1973 |
Granulomatous hepatitis and prolonged fever of unknown origin: a study of 13 patients.
Topics: Adult; Ascites; Dexamethasone; Edema; Female; Fever; Fever of Unknown Origin; Granuloma; Hepatitis; | 1973 |
[Recurring fever bouts].
Topics: Etiocholanolone; Familial Mediterranean Fever; Fever; Humans; Indomethacin; Male; Middle Aged; Recur | 1973 |
Pharmacological study on a new analgesic-anti-inflammatory drug: alpha-(4-(1-oxo-2-iso-indolinyl)-phenyl)-propionic acid of K 4277.
Topics: Adjuvants, Immunologic; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Behavi | 1973 |
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr | 1973 |
Antipyretic effect of indomethacin in patients with malignancy.
Topics: Anti-Bacterial Agents; Body Temperature; Female; Fever; Hodgkin Disease; Humans; Indomethacin; Leuke | 1968 |
Anti-inflammatory and other properties of 2,3-dihydrol-1-H-pyridino-(2,3- b) (1,4)-thiazine-2-one; ABBott-29590.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Dogs; Edema; Fever; Gastric Mucos | 1972 |
[Indomethacin in combination with anticoagulants in the treatment thrombophlebitis].
Topics: Aged; Anticoagulants; Drug Combinations; Edema; Female; Fever; Humans; Indomethacin; Male; Pain; Thr | 1972 |
[Anti-inflammatory effect of bimetopyrol. I. Suppressive effect on acute inflammation].
Topics: Animals; Anti-Inflammatory Agents; Aspirin; Cyproheptadine; Edema; Erythema; Fever; Flufenamic Acid; | 1972 |
Pharmacological investigations of 4-prenyl-1,2-diphenyl-3,5-pyrazolidinedione (DA 2370). 7. Pharmacological comparison with standard anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Benzyl Compounds; Edema; Female; Fever; Flufenamic Acid; Indometh | 1972 |
Fever responses to bacterial pyrogens in guinea pigs and application for screening of antipyretic agents.
Topics: Acetaminophen; Aminopyrine; Analgesics; Animals; Aspirin; Body Temperature; Female; Fever; Flufenami | 1968 |
[On the therapy of etiocholanolone fever].
Topics: Adolescent; Adult; Betamethasone; Child; Etiocholanolone; Female; Fever; Humans; Indomethacin; Male; | 1967 |
Indomethacin: as an antipyretic agent in pediatrics.
Topics: Analgesics; Animals; Body Temperature; Child; Fever; Humans; Indomethacin; Rabbits; Rats; Time Facto | 1968 |
The assay of anti-pyretic drugs in mice, using intracerebral injection of pyretogenins.
Topics: Acetaminophen; Analgesics; Animals; Antipyrine; Aspirin; Biological Assay; Body Temperature; Cerebra | 1968 |
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car | 1969 |
Control of fever in Hodgkin's disease by indomethacin.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Aspirin; Female; Fever | 1965 |
[On the antipyretic action of indomethacin in Hodgkin's lymphogranuloma and in neoplasms].
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Antineoplastic Agents; Fever; Hodgkin Disease; Human | 1966 |