indomethacin has been researched along with Pulpitis in 7 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Pulpitis: Inflammation of the DENTAL PULP, usually due to bacterial infection in dental caries, tooth fracture, or other conditions causing exposure of the pulp to bacterial invasion. Chemical irritants, thermal factors, hyperemic changes, and other factors may also cause pulpitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia." | 9.14 | The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010) |
| "In a randomized double-blinded clinical trial, 150 patients (50 per group) with irreversible pulpitis were given placebo, 600 mg ibuprofen, or 75 mg indomethacin 1 hour before local anesthesia." | 5.14 | The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis. ( Abbott, PV; Ashouri, R; Askarifard, S; Nakhaee, N; Pardakhti, A; Parirokh, M; Rekabi, AR, 2010) |
| "Following the induction of experimental pulpitis in baboon teeth, calf skin collagen, indomethacin, or zinc oxide-eugenol was used to dress exposed dental pulp wounds in selected teeth." | 3.67 | The effect of collagen and indomethacin on inflamed dental pulp wounds of baboon teeth. ( Dover, MS; Franklin, CJ; Oguntebi, BR; Tuwaijri, AS, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parirokh, M | 1 |
| Ashouri, R | 1 |
| Rekabi, AR | 1 |
| Nakhaee, N | 1 |
| Pardakhti, A | 1 |
| Askarifard, S | 1 |
| Abbott, PV | 1 |
| Benoliel, R | 1 |
| Sharav, Y | 1 |
| Ohnishi, T | 1 |
| Suwa, M | 1 |
| Oyama, T | 1 |
| Arakaki, N | 1 |
| Torii, M | 1 |
| Daikuhara, Y | 1 |
| Lin, SK | 1 |
| Kuo, MY | 1 |
| Wang, JS | 1 |
| Lee, JJ | 1 |
| Wang, CC | 1 |
| Huang, S | 1 |
| Shun, CT | 1 |
| Hong, CY | 1 |
| Okiji, T | 2 |
| Morita, I | 2 |
| Sunada, I | 2 |
| Murota, S | 2 |
| Oguntebi, BR | 1 |
| Dover, MS | 1 |
| Franklin, CJ | 1 |
| Tuwaijri, AS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Electroacupuncture (EA) on the Success of Inferior Alveolar Nerve Block (IANB) and Post-operative Pain Relief in Mandibular Molar With Symptomatic Irreversible Pulpitis (SIP) Among Malaysians: A Study Protocol for Randomized Double-Blinded C[NCT04804761] | 20 participants (Anticipated) | Interventional | 2023-01-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for indomethacin and Pulpitis
| Article | Year |
|---|---|
Paroxysmal hemicrania. Case studies and review of the literature.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Cluster Headache; Conjunctiva | 1998 |
1 trial available for indomethacin and Pulpitis
| Article | Year |
|---|---|
The effect of premedication with ibuprofen and indomethacin on the success of inferior alveolar nerve block for teeth with irreversible pulpitis.
Topics: Adult; Analysis of Variance; Anesthesia, Dental; Anesthetics, Local; Anti-Inflammatory Agents, Non-S | 2010 |
5 other studies available for indomethacin and Pulpitis
| Article | Year |
|---|---|
Prostaglandin E2 predominantly induces production of hepatocyte growth factor/scatter factor in human dental pulp in acute inflammation.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cells, Cultured; Chi | 2000 |
Differential regulation of interleukin-6 and inducible cyclooxygenase gene expression by cytokines through prostaglandin-dependent and -independent mechanisms in human dental pulp fibroblasts.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blotting, Northern; Cells, Cultured; Cyclooxygenase 2; Cycl | 2002 |
The role of leukotriene B4 in neutrophil infiltration in experimentally-induced inflammation of rat tooth pulp.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Cell Movement; Cyclophosphami | 1991 |
Involvement of arachidonic acid metabolites in increases in vascular permeability in experimental dental pulpal inflammation in the rat.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; | 1989 |
The effect of collagen and indomethacin on inflamed dental pulp wounds of baboon teeth.
Topics: Animals; Collagen; Dental Pulp; Dental Pulp Necrosis; Dentin, Secondary; Indomethacin; Papio; Pulpit | 1988 |