indomethacin has been researched along with Pulmonary Arterial Remodeling in 4 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, PVR was induced in pups in utero by exposure of pregnant dams to indomethacin and hypoxia and cardiac lipids, echocardiographic function and cardiomyocyte mitochondrial function were subsequently examined." | 4.12 | Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups. ( Cole, LK; Dolinsky, VW; Hatch, GM; Sparagna, GC, 2022) |
| "CSA hypertension was associated with renal perivascular fibrosis and divergent changes in immunohistochemical signals of renal arteriolar ETA (increases) and ETB (decreases) receptors." | 1.42 | Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling. ( Ali, RM; El-Gowelli, HM; El-Mas, MM; Helmy, MW, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cole, LK | 1 |
| Sparagna, GC | 1 |
| Dolinsky, VW | 1 |
| Hatch, GM | 1 |
| Westergren-Thorsson, G | 1 |
| Bagher, M | 1 |
| Andersson-Sjöland, A | 1 |
| Thiman, L | 1 |
| Löfdahl, CG | 1 |
| Hallgren, O | 1 |
| Bjermer, L | 1 |
| Larsson-Callerfelt, AK | 1 |
| El-Mas, MM | 1 |
| Helmy, MW | 1 |
| Ali, RM | 1 |
| El-Gowelli, HM | 1 |
| Perez-Ternero, C | 1 |
| Rodriguez-Rodriguez, R | 1 |
| Herrera, MD | 1 |
| Alvarez de Sotomayor, M | 1 |
4 other studies available for indomethacin and Pulmonary Arterial Remodeling
| Article | Year |
|---|---|
Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups.
Topics: Animals; Animals, Newborn; Cardiolipins; Disease Models, Animal; Female; Hypoxia; Indomethacin; Mito | 2022 |
VEGF synthesis is induced by prostacyclin and TGF-β in distal lung fibroblasts from COPD patients and control subjects: Implications for pulmonary vascular remodelling.
Topics: Aged; Biglycan; Cell Movement; Cell Proliferation; Cells, Cultured; Cyclooxygenase Inhibitors; Fibro | 2018 |
Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Celecoxib; Cyclosporine; Cytoprote | 2015 |
Diet supplementation with rice bran enzymatic extract restores endothelial impairment and wall remodelling of ApoE(-/-) mice microvessels.
Topics: Animals; Apamin; Arteries; Charybdotoxin; Collagen; Dietary Supplements; Elastin; Endothelium, Vascu | 2016 |