indomethacin has been researched along with Primary Peritonitis in 65 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility of inducing peritoneal inflammation in three murine species (gerbils, rats and mice) via the oral administration of indomethacin was investigated with the overall aim of developing an experimental animal model for human peritonitis." | 7.73 | Experimental peritonitis induced by oral administration of indomethacin in Mongolian gerbils. ( Kim, O; Lee, JU, 2006) |
| "We determined the importance of prostanoid production in the enhanced protein loss observed during acute peritonitis by inhibition experiments using indomethacin, an inhibitor of cyclooxygenase activity." | 7.71 | Effect of indomethacin on peritoneal protein loss in a rabbit model of peritonitis. ( Cheung, AK; Kamerath, CD; Leypoldt, JK; Peng, H; Reimer, LG, 2001) |
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 7.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| "Salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their complexes [Zn(LASSBio-466)H(2)O](2) (1) and [Zn(HLASSBio-1064)Cl](2) (2) were evaluated in animal models of peripheral and central nociception, and acute inflammation." | 3.77 | Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes. ( Alexandre-Moreira, MS; Alves, MA; Barreiro, EJ; Beraldo, H; Castellano, EE; Júnior, WB; Lima, LM; Parrilha, GL; Perez-Rebolledo, A; Piro, OE, 2011) |
| "The possibility of inducing peritoneal inflammation in three murine species (gerbils, rats and mice) via the oral administration of indomethacin was investigated with the overall aim of developing an experimental animal model for human peritonitis." | 3.73 | Experimental peritonitis induced by oral administration of indomethacin in Mongolian gerbils. ( Kim, O; Lee, JU, 2006) |
| "The anti-inflammatory effect of the leaves of Bryonia laciniosa was evaluated using carrageenan, dextran, histamine, serotonin induced rat paw oedema and cotton pellet induced granuloma (chronic) models in rats." | 3.72 | Evaluation of anti-inflammatory activity of chloroform extract of Bryonia laciniosa in experimental animal models. ( Gupta, M; Karki, SS; Manikandan, L; Mazumdar, UK; Sambathkumar, R; Sivakumar, T; Vamsi, ML, 2003) |
| "We determined the importance of prostanoid production in the enhanced protein loss observed during acute peritonitis by inhibition experiments using indomethacin, an inhibitor of cyclooxygenase activity." | 3.71 | Effect of indomethacin on peritoneal protein loss in a rabbit model of peritonitis. ( Cheung, AK; Kamerath, CD; Leypoldt, JK; Peng, H; Reimer, LG, 2001) |
| " Prostaglandin inhibition in continuous ambulatory peritoneal dialysis (CAPD) patients during peritonitis using indomethacin intraperitoneally was found to decrease the intrinsic permeability to macromolecules." | 3.71 | Prostaglandin inhibition by intraperitoneal indomethacin has no effect on peritoneal permeability during stable CAPD. ( de Waart, DR; Douma, CE; Krediet, RT; Struijk, DG; Zemel, D, 2001) |
| " SK&F 105809 inhibited oedema and inflammatory-cell infiltration in arachidonic acid-induced inflammation in the mouse ear and rat paw as well as in carrageenan- and monosodium urate crystal-induced peritonitis." | 3.68 | Pharmacological profile of SK&F 105809, a dual inhibitor of arachidonic acid metabolism. ( Adams, J; Bender, P; Dimartino, MJ; Griswold, DE; Hanna, N; Kirsh, R; Marshall, PJ; Newton, J; Schwartz, L, 1990) |
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 3.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| " When the effect of anticomplementary agents (FUT-175 and K-76 COONa) and anti-inflammatory drugs (indomethacin and dexamethasone) on phytohemagglutinin-induced peritonitis was examined, FUT-175, K-76 COONa and indomethacin suppressed only the plasma protein exudation." | 3.67 | Studies on phytohemagglutinin-induced peritonitis of mice: dynamics of inflammatory responses and influence of anticomplementary agents and anti-inflammatory drugs. ( Ishibashi, Y; Nagaoka, I; Yamashita, T, 1987) |
| " The effects of ibuprofen, methylprednisolone-sodium succinate, and gentamicin alone, or in combination on survival time and, TxA2 and PGI2 production in rats in a LD100 fecal peritonitis shock model were assessed." | 3.67 | Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock. ( Cook, JA; Halushka, PV; Knapp, RG; Wise, WC, 1985) |
| "We investigated the effects of the thromboxane synthetase inhibitor 7-(1-imidazolyl)heptanoic acid (7-IHA) and the fatty acid cyclooxygenase inhibitors indomethacin or ibuprofen in the treatment of fecal peritonitis in the rat." | 3.66 | Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production. ( Butler, RR; Cook, JA; Halushka, PV; Wise, WC, 1983) |
| "Indomethacin given orally to conventional rats produced in three days a syndrome, often fatal, of intestinal lesions characterized by multiple ulcers and peritonitis." | 3.65 | Resistance of germfree rats to indomethacin-induced intestinal lesions. ( Asano, T; Robert, A, 1977) |
| "Indomethacin was given intraperitoneally during the first 3 days." | 2.68 | Effects of intraperitoneal cyclooxygenase inhibition on inflammatory mediators in dialysate and peritoneal membrane characteristics during peritonitis in continuous ambulatory peritoneal dialysis. ( Dinkla, C; Krediet, RT; Stolk, LM; Struijk, DG; ten Berge, IJ; Zemel, D, 1995) |
| "Methods used included the in-vitro inhibition of cyclooxygenase-1 and -2, in-vivo evaluation of anti-inflammatory activity by air pouch and peritonitis models and the pharmacokinetic profile after intravenous (3 mg/kg) and oral (3 and 6 mg/kg) dosing to rats." | 1.35 | Preclinical pharmacokinetic and pharmacodynamic evaluation of thiazolidinone PG15: an anti-inflammatory candidate. ( da Silva, TG; Dalla Costa, T; de Lima, Mdo C; Galdino, SL; Pitta, Ida R; Uchôa, Fde T, 2009) |
| "Peritonitis was induced by cecal ligation and puncture in 8 rats." | 1.35 | Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis. ( Altun, A; Bagcivan, I; Durmus, N; Guney, C; Karadas, B; Kaya, T; Koyluoglu, G, 2008) |
| " Male Sprague-Dawley rats were dosed with two doses of metronidazole (50 mg/kg, 12 and 1 h pre-NSAID) or a single 100 mg/kg dose of tempo 1 h prior to NSAIDs." | 1.30 | Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers. ( Davies, NM; Jamali, F, 1997) |
| "On the carrageenin-induced pleurisy, fepradinol (100 mg/kg p." | 1.29 | Effects of fepradinol on rat acute models of vascular permeability and leucocyte migration. ( Conde, JR; Martorell, J; Masso, JM; Villar, AM, 1994) |
| "Bilateral hyperalgesia was observed when this factor, denoted macrophage hyperalgesic factor (MHF), was injected into one hind paw or into the peritoneal cavity of the rat." | 1.27 | Interleukin-1 mimics the hyperalgesia induced by a factor obtained by macrophage lysis. ( Ferreira, SH; Francischi, JN; Lorenzetti, BB, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (41.54) | 18.7374 |
| 1990's | 14 (21.54) | 18.2507 |
| 2000's | 13 (20.00) | 29.6817 |
| 2010's | 10 (15.38) | 24.3611 |
| 2020's | 1 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, H | 1 |
| Altenbach, RJ | 1 |
| Carr, TL | 1 |
| Chandran, P | 1 |
| Hsieh, GC | 1 |
| Lewis, LG | 1 |
| Manelli, AM | 1 |
| Milicic, I | 1 |
| Marsh, KC | 1 |
| Miller, TR | 1 |
| Strakhova, MI | 1 |
| Vortherms, TA | 1 |
| Wakefield, BD | 1 |
| Wetter, JM | 1 |
| Witte, DG | 1 |
| Honore, P | 1 |
| Esbenshade, TA | 1 |
| Brioni, JD | 1 |
| Cowart, MD | 1 |
| da Silva, YK | 1 |
| Augusto, CV | 1 |
| de Castro Barbosa, ML | 1 |
| de Albuquerque Melo, GM | 1 |
| de Queiroz, AC | 1 |
| de Lima Matos Freire Dias, T | 1 |
| Júnior, WB | 2 |
| Barreiro, EJ | 2 |
| Lima, LM | 3 |
| Alexandre-Moreira, MS | 5 |
| dos Santos, JL | 1 |
| Lanaro, C | 1 |
| Gambero, S | 1 |
| Franco-Penteado, CF | 1 |
| Wade, M | 1 |
| Yerigenahally, S | 1 |
| Kutlar, A | 1 |
| Meiler, SE | 1 |
| Costa, FF | 1 |
| Chung, M | 1 |
| Hanke, T | 1 |
| Dehm, F | 1 |
| Liening, S | 1 |
| Popella, SD | 1 |
| Maczewsky, J | 1 |
| Pillong, M | 1 |
| Kunze, J | 1 |
| Weinigel, C | 2 |
| Barz, D | 2 |
| Kaiser, A | 1 |
| Wurglics, M | 1 |
| Lämmerhofer, M | 1 |
| Schneider, G | 1 |
| Sautebin, L | 2 |
| Schubert-Zsilavecz, M | 1 |
| Werz, O | 2 |
| Koeberle, A | 1 |
| Muñoz, E | 1 |
| Appendino, GB | 1 |
| Minassi, A | 1 |
| Pace, S | 1 |
| Rossi, A | 1 |
| Caprioglio, D | 1 |
| Collado, JA | 1 |
| de Meneses Santos, R | 1 |
| Barros, PR | 1 |
| Bortoluzzi, JH | 1 |
| Meneghetti, MR | 1 |
| da Silva, YKC | 1 |
| da Silva, AE | 1 |
| da Silva Santos, M | 1 |
| Meira, CS | 1 |
| Dos Santos Filho, JM | 1 |
| Sousa, CC | 1 |
| Anjos, PS | 1 |
| Cerqueira, JV | 1 |
| Dias Neto, HA | 1 |
| da Silveira, RG | 1 |
| Russo, HM | 1 |
| Wolfender, JL | 1 |
| Queiroz, EF | 1 |
| Moreira, DRM | 1 |
| Soares, MBP | 1 |
| Nascimento, WM | 1 |
| Oliveira, JRS | 1 |
| Cunha, RX | 1 |
| Gambôa, DSR | 1 |
| Silva, APS | 1 |
| Lima, VLM | 1 |
| Peters, BM | 1 |
| Noverr, MC | 1 |
| Uchôa, Fde T | 1 |
| da Silva, TG | 1 |
| de Lima, Mdo C | 1 |
| Galdino, SL | 1 |
| Pitta, Ida R | 1 |
| Dalla Costa, T | 1 |
| Vilela, FC | 1 |
| Bitencourt, AD | 1 |
| Cabral, LD | 1 |
| Franqui, LS | 1 |
| Soncini, R | 1 |
| Giusti-Paiva, A | 1 |
| Alves, MA | 1 |
| Perez-Rebolledo, A | 1 |
| Parrilha, GL | 1 |
| Castellano, EE | 1 |
| Piro, OE | 1 |
| Beraldo, H | 1 |
| Cavalcante-Silva, LHA | 1 |
| Barbosa Brito da Matta, C | 1 |
| De Araújo, MV | 1 |
| Barbosa-Filho, JM | 1 |
| Pereira de Lira, D | 1 |
| De Oliveira Santos, BV | 1 |
| De Miranda, GEC | 1 |
| Gupta, M | 1 |
| Mazumdar, UK | 1 |
| Sivakumar, T | 1 |
| Vamsi, ML | 1 |
| Karki, SS | 1 |
| Sambathkumar, R | 1 |
| Manikandan, L | 1 |
| VECCHIO, C | 1 |
| FONTANA, A | 1 |
| TAVAZZI, L | 1 |
| Abdel-Salam, OM | 1 |
| Kim, O | 1 |
| Lee, JU | 1 |
| Leypoldt, JK | 2 |
| Kamerath, CD | 2 |
| Gilson, JF | 1 |
| Koyluoglu, G | 1 |
| Bagcivan, I | 1 |
| Karadas, B | 1 |
| Guney, C | 1 |
| Durmus, N | 1 |
| Altun, A | 1 |
| Kaya, T | 1 |
| Butler, RR | 2 |
| Wise, WC | 3 |
| Halushka, PV | 3 |
| Cook, JA | 3 |
| Fink, MP | 2 |
| MacVittie, TJ | 2 |
| Casey, LC | 2 |
| Joncic, DL | 1 |
| Dreher, R | 1 |
| Fink, K | 1 |
| Seidel, H | 1 |
| Wagner, P | 1 |
| Rohrbach, B | 1 |
| Federlin, K | 1 |
| Short, BL | 1 |
| Gardiner, M | 1 |
| Walker, RI | 1 |
| Jones, SR | 1 |
| Fletcher, JR | 1 |
| Török, K | 1 |
| Németh, K | 1 |
| Erdö, F | 1 |
| Arányi, P | 1 |
| Székely, JI | 1 |
| Zemel, D | 2 |
| Struijk, DG | 2 |
| Dinkla, C | 1 |
| Stolk, LM | 1 |
| ten Berge, IJ | 1 |
| Krediet, RT | 2 |
| Zuany-Amorim, C | 1 |
| Leduc, D | 1 |
| Vargaftig, BB | 1 |
| Pretolani, M | 1 |
| Masso, JM | 1 |
| Villar, AM | 1 |
| Conde, JR | 1 |
| Martorell, J | 1 |
| Dauksas, V | 1 |
| Gaidelis, P | 1 |
| Udrènaitè, E | 1 |
| Kuliesius, V | 1 |
| Labanauskas, L | 1 |
| Sugimoto, K | 1 |
| Kawamura, M | 1 |
| Katori, M | 1 |
| Shindo, M | 1 |
| Ohwada, T | 1 |
| De La Puerta, R | 2 |
| Martinez, E | 2 |
| Bravo, L | 1 |
| Ahumada, MC | 1 |
| Ahumada, C | 1 |
| Sáenz, T | 1 |
| García, D | 1 |
| Fernandez, A | 1 |
| Davies, NM | 1 |
| Jamali, F | 1 |
| Grzegorzewska, AE | 1 |
| Goulet, JL | 1 |
| Byrum, RS | 1 |
| Key, ML | 1 |
| Nguyen, M | 1 |
| Wagoner, VA | 1 |
| Koller, BH | 1 |
| Gross, G | 1 |
| Imamura, T | 1 |
| Vogt, SK | 1 |
| Wozniak, DF | 1 |
| Nelson, DM | 1 |
| Sadovsky, Y | 1 |
| Muglia, LJ | 1 |
| Peng, H | 1 |
| Cheung, AK | 1 |
| Reimer, LG | 1 |
| Douma, CE | 1 |
| de Waart, DR | 1 |
| Takahashi, H | 1 |
| Ohno, N | 1 |
| Adachi, Y | 1 |
| Yadomae, T | 1 |
| Kolaczkowska, E | 1 |
| Shahzidi, S | 1 |
| Seljelid, R | 1 |
| van Rooijen, N | 1 |
| Plytycz, B | 1 |
| Arrigoni-Martelli, E | 1 |
| Bramm, E | 1 |
| Binderup, L | 1 |
| Robert, A | 1 |
| Asano, T | 1 |
| Maruyama, Y | 1 |
| Terasawa, M | 1 |
| Anami, K | 1 |
| Kadobe, Y | 1 |
| Marshall, LA | 1 |
| Murphy, J | 1 |
| Marinari, L | 1 |
| Chang, J | 1 |
| Fieren, MW | 1 |
| van den Bemd, GJ | 1 |
| Ben-Efraim, S | 1 |
| Bonta, IL | 1 |
| Shany, S | 1 |
| Rapoport, J | 1 |
| Zuili, I | 1 |
| Gavriel, A | 1 |
| Lavi, N | 1 |
| Chaimovitz, C | 1 |
| Hanna, N | 1 |
| Marshall, PJ | 1 |
| Newton, J | 1 |
| Schwartz, L | 1 |
| Kirsh, R | 1 |
| Dimartino, MJ | 1 |
| Adams, J | 1 |
| Bender, P | 1 |
| Griswold, DE | 1 |
| Francischi, JN | 1 |
| Lorenzetti, BB | 1 |
| Ferreira, SH | 1 |
| Steinhauer, HB | 1 |
| Schollmeyer, P | 1 |
| Narisawa, T | 1 |
| Takahashi, M | 1 |
| Masuda, T | 1 |
| Nagasawa, O | 1 |
| Koyama, H | 1 |
| Schirmer, WJ | 1 |
| Schirmer, JM | 1 |
| Townsend, MC | 1 |
| Fry, DE | 1 |
| Nagaoka, I | 1 |
| Ishibashi, Y | 1 |
| Yamashita, T | 1 |
| Knapp, RG | 1 |
| Julou, L | 1 |
| Guyonnet, JC | 1 |
| Ducrot, R | 1 |
| Bardone, MC | 1 |
| Detaille, JY | 1 |
| Laffargue, B | 1 |
| Selye, H | 3 |
| Tomisawa, S | 1 |
| Sato, NL | 1 |
| Warshaw, AL | 1 |
| Ehrlich, CE | 1 |
| Wharton, JT | 1 |
| Gallager, HS | 1 |
| Martino, A | 1 |
| De Risi, F | 1 |
| Faiella, F | 1 |
| Kent, TH | 1 |
| Cardelli, RM | 1 |
| Stamler, FW | 1 |
| Yamamoto, H | 1 |
| Saito, C | 1 |
| Okamoto, T | 1 |
| Awata, H | 1 |
| Inukai, T | 1 |
| Hirohashi, A | 1 |
| Yukawa, Y | 1 |
1 review available for indomethacin and Primary Peritonitis
| Article | Year |
|---|---|
[Intraperitoneal administration of drugs in patients treated with peritoneal dialysis].
Topics: Anti-Bacterial Agents; Calcitriol; Calcium Channel Blockers; Cytokines; Dialysis Solutions; Drug Sta | 1997 |
1 trial available for indomethacin and Primary Peritonitis
| Article | Year |
|---|---|
Effects of intraperitoneal cyclooxygenase inhibition on inflammatory mediators in dialysate and peritoneal membrane characteristics during peritonitis in continuous ambulatory peritoneal dialysis.
Topics: Adult; Aged; beta 2-Microglobulin; Cell Membrane Permeability; Dinoprostone; Female; Humans; Indomet | 1995 |
63 other studies available for indomethacin and Primary Peritonitis
| Article | Year |
|---|---|
cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzofurans; Carrageenan; Disease Models, Animal; | 2008 |
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Ear; Edema; Female; Freund's Adjuvant; Hyd | 2010 |
Design, synthesis, and pharmacological evaluation of novel hybrid compounds to treat sickle cell disease symptoms.
Topics: Acetic Acid; Analgesics; Anemia, Sickle Cell; Animals; Anti-Inflammatory Agents; Antisickling Agents | 2011 |
Aminothiazole-featured pirinixic acid derivatives as dual 5-lipoxygenase and microsomal prostaglandin E2 synthase-1 inhibitors with improved potency and efficiency in vivo.
Topics: Animals; Arachidonate 5-Lipoxygenase; Binding Sites; Drug Design; Humans; Hydrophobic and Hydrophili | 2013 |
SAR studies on curcumin's pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase.
Topics: Animals; Anti-Inflammatory Agents; Arachidonate 5-Lipoxygenase; Curcumin; Humans; Lipoxygenase Inhib | 2014 |
Synthesis and evaluation of the anti-nociceptive and anti-inflammatory activity of 4-aminoquinoline derivatives.
Topics: Aminoquinolines; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Freund's Adjuvant; Male; | 2015 |
Structural design, synthesis and substituent effect of hydrazone-N-acylhydrazones reveal potent immunomodulatory agents.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Crystallography, X-Ray; Dinoprostone; Disease Mode | 2018 |
Evaluation of the treatment of fever, pain and inflammation with Indigofera suffruticosa Miller Leaves Aqueous Extract.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antipyretics; Fever; Indigofera; Indomethacin; Inflam | 2022 |
Candida albicans-Staphylococcus aureus polymicrobial peritonitis modulates host innate immunity.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Candida albicans; Candidiasis; Coinfection; Enzyme | 2013 |
Preclinical pharmacokinetic and pharmacodynamic evaluation of thiazolidinone PG15: an anti-inflammatory candidate.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents; Cyclooxygenase 1; Cyclooxygenase 2; Cycloox | 2009 |
Anti-inflammatory and antipyretic effects of Sonchus oleraceus in rats.
Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cotton Fiber; Disease Models, Animal; Edema; Fever; | 2010 |
Analgesic and anti-inflammatory activities of salicylaldehyde 2-chlorobenzoyl hydrazone (H(2)LASSBio-466), salicylaldehyde 4-chlorobenzoyl hydrazone (H(2)LASSBio-1064) and their zinc(II) complexes.
Topics: Acetic Acid; Aldehydes; Analgesics; Animals; Anti-Inflammatory Agents; Coordination Complexes; Cryst | 2011 |
Antinociceptive and anti-inflammatory activities of crude methanolic extract of red alga Bryothamnion triquetrum.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Dipyrone; Female; Indomethacin; Leukocytes; Male; Met | 2012 |
Evaluation of anti-inflammatory activity of chloroform extract of Bryonia laciniosa in experimental animal models.
Topics: Animals; Anti-Inflammatory Agents; Bryonia; Carrageenan; Chloroform; Dextrans; Edema; Exudates and T | 2003 |
[ON THE GASTRO-LESIONAL EFFECT OF INDOMETHACIN].
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Indoles; Indomethacin; Peptic Ulcer Perforation; | 1964 |
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats.
Topics: Acetic Acid; Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capsaicin; | 2005 |
Experimental peritonitis induced by oral administration of indomethacin in Mongolian gerbils.
Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Female; Gerbillinae; Indomethacin; | 2006 |
Enhanced local production of vascular endothelial growth factor is not sufficient to increase peritoneal permeability to protein during acute peritonitis.
Topics: Acute Disease; Animals; Gene Expression Regulation; Indomethacin; Male; Peritoneum; Peritonitis; Per | 2007 |
Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis.
Topics: Animals; Celecoxib; Guanidines; Ileum; In Vitro Techniques; Indomethacin; Jejunum; Male; Muscle Cont | 2008 |
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
Topics: Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinogen Degradation Products; Genta | 1983 |
Effects of nonsteroidal anti-inflammatory drugs on renal function in septic dogs.
Topics: Animals; Anti-Inflammatory Agents; Dogs; Escherichia coli Infections; Female; Glomerular Filtration | 1984 |
Inhibition of prostaglandin synthesis restores normal hemodynamics in canine hyperdynamic sepsis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Dogs; Escherichia coli Infections; Fe | 1984 |
[Inflammatory conditions and indomethacin. Modification of severe life-threatening infections following surgery and injuries with indomethacin].
Topics: Accidents, Traffic; Adult; Female; Humans; Indomethacin; Male; Peritonitis; Surgical Wound Infection | 1983 |
[Immunomodulation by symptomaticly active antirheumatic agents].
Topics: Animals; Anti-Inflammatory Agents; Arthritis; Autoradiography; Dexamethasone; Disease Models, Animal | 1983 |
Thromboxane and prostacyclin production during septic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Fatty Acids, Essential; Female; Fibrin Fibrinog | 1982 |
Indomethacin improves survival in gram-negative sepsis.
Topics: Animals; Blood Pressure; Disease Models, Animal; Escherichia coli Infections; Indomethacin; Leukocyt | 1981 |
Measurement and drug induced modulation of interleukin-1 level during zymosan peritonitis in mice.
Topics: Analysis of Variance; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Bi | 1995 |
Characterization and pharmacological modulation of antigen-induced peritonitis in actively sensitized mice.
Topics: Animals; Benzeneacetamides; Cetirizine; Cycloheximide; Dexamethasone; Eosinophils; Histamine Release | 1993 |
Effects of fepradinol on rat acute models of vascular permeability and leucocyte migration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Carrageenan; Chemotaxis, L | 1994 |
Synthesis and anti-inflammatory properties of 1,2-dialkoxy-4-(3-dimethylaminopropionyl)benzenes and their 5-halogeno derivatives.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Experimental; Aspirin; Edema; Foot Inju | 1994 |
Transmigration routes and a delayed systemic hypotension in rats after intraperitoneal injection of endotoxin from Escherichia coli.
Topics: Animals; Body Temperature; Dinoprostone; Endotoxins; Escherichia coli; Exudates and Transudates; Hem | 1993 |
Effect of silymarin on different acute inflammation models and on leukocyte migration.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Movement; Ear, External; Edema; | 1996 |
The effects of a triterpene fraction isolated from Crataegus monogyna Jacq. on different acute inflammation models in rats and mice. Leucocyte migration and phospholipase A2 inhibition.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cell Migrat | 1997 |
Pharmacological protection of NSAID-induced intestinal permeability in the rat: effect of tempo and metronidazole as potential free radical scavengers.
Topics: Administration, Oral; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biomar | 1997 |
Genetic factors determine the contribution of leukotrienes to acute inflammatory responses.
Topics: Acute Disease; Animals; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Crosses, Genetic; Ear, Extern | 2000 |
Inhibition of cyclooxygenase-2 prevents inflammation-mediated preterm labor in the mouse.
Topics: Animals; Blotting, Northern; Calcium; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2000 |
Effect of indomethacin on peritoneal protein loss in a rabbit model of peritonitis.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cell Movement; Cyclooxygenase Inhibitors; Dialysis Solutions; | 2001 |
Prostaglandin inhibition by intraperitoneal indomethacin has no effect on peritoneal permeability during stable CAPD.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability; Humans; Indomethacin; | 2001 |
Association of immunological disorders in lethal side effect of NSAIDs on beta-glucan-administered mice.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; beta-Glucans; Butanones; Col | 2001 |
Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Capillary Leak Syndrome; Capillary Permeability; Cyclooxygena | 2002 |
Actinomycin D peritonitis in rats: a tool for the study of early events in inflammation.
Topics: Animals; Cell Movement; Cyclic AMP; Cyclic GMP; Dactinomycin; Disease Models, Animal; Female; Flupre | 1976 |
Resistance of germfree rats to indomethacin-induced intestinal lesions.
Topics: Animals; Escherichia coli; Female; Germ-Free Life; Indomethacin; Intestinal Diseases; Intestines; Ma | 1977 |
[Pharmacological studies of 2-(5H-(1)benzopyrano(2,3-b)pyridin-7-yl)propionic acid (Y-8004). (I) Anti-inflammatory, analgesic and antipyretic actions].
Topics: Adrenal Cortex; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Capillary Permeability | 1975 |
Characterization and pharmacological modulation of soluble phospholipase A2 generated during glycogen-induced rat peritonitis.
Topics: Animals; Cell Movement; Dexamethasone; Female; Glycogen; Indomethacin; Injections, Intraperitoneal; | 1992 |
Prostaglandin E2 inhibits the release of tumor necrosis factor-alpha, rather than interleukin 1 beta, from human macrophages.
Topics: Cells, Cultured; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indomethacin; Inte | 1992 |
Metabolism of 25-OH-vitamin D3 by peritoneal macrophages from CAPD patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcifediol; Calcitriol; Chromatography, High Pressure Liqu | 1991 |
Pharmacological profile of SK&F 105809, a dual inhibitor of arachidonic acid metabolism.
Topics: Administration, Oral; Analgesics; Animals; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimen | 1990 |
Interleukin-1 mimics the hyperalgesia induced by a factor obtained by macrophage lysis.
Topics: Animals; Carrageenan; Guinea Pigs; Hyperalgesia; Hyperesthesia; Indomethacin; Interleukin-1; Macroph | 1988 |
Prostaglandin-mediated loss of proteins during peritonitis in continuous ambulatory peritoneal dialysis.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Dinoprost; Dinoprostone; Female; Humans; Indomethacin; Ma | 1986 |
[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin].
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Dinoprostone; D | 1987 |
Imidazole and indomethacin improve hepatic perfusion in sepsis.
Topics: Animals; Female; Hemodynamics; Imidazoles; Indomethacin; Liver Circulation; Peritonitis; Rats; Rats, | 1987 |
Studies on phytohemagglutinin-induced peritonitis of mice: dynamics of inflammatory responses and influence of anticomplementary agents and anti-inflammatory drugs.
Topics: Animals; Anti-Inflammatory Agents; Benzamidines; Blood Proteins; Complement Inactivator Proteins; De | 1987 |
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Disease Models, Animal; Drug Therapy, Combination; Female; Ge | 1985 |
[General pharmacological properties of methiazinic acid (16091 RP)].
Topics: Abscess; Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis; Autonomic Nervous Syste | 1969 |
Prevention of indomethacin-induced intestinal ulcers by various catatoxic steroids.
Topics: Adrenal Cortex Hormones; Animals; Antitoxins; Chemical Phenomena; Chemistry; Corticosterone; Ethyles | 1970 |
Preventive and curative effects of non-steroidal anti-inflammatory drugs on experimental peritoneal inflammation in mice.
Topics: Animals; Anti-Inflammatory Agents; Ascitic Fluid; Aspirin; Capillary Permeability; Coloring Agents; | 1973 |
Management of starch peritonitis without the unnecessary second operation.
Topics: Adult; Anti-Inflammatory Agents; Ascitic Fluid; Female; Gloves, Surgical; Humans; Indomethacin; Male | 1973 |
Starch granulomatous peritonitis.
Topics: Adult; Diagnosis, Differential; Fallopian Tubes; Female; Foreign Bodies; Gloves, Surgical; Humans; I | 1974 |
Effect of catatoxic steroids upon established morbid changes.
Topics: Animals; Digitoxin; Female; Indomethacin; Intestine, Small; Nitriles; Peritonitis; Poisoning; Pregne | 1971 |
Prevention of indomethacin-induced intestinal ulcers by spironolactone and norbolethone.
Topics: Anabolic Agents; Animals; Digestive System; Female; Indomethacin; Peptic Ulcer; Peritonitis; Rats; S | 1969 |
[Preliminary results of the therapeutic use of a non-steroid anti-inflammatory agent in tubercular pathology].
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Indomethacin; Male; Middle Aged; Peritonitis; Pleura | 1968 |
Small intestinal ulcers and intestinal flora in rats given indomethacin.
Topics: Animals; Anti-Bacterial Agents; Cecal Diseases; Ileum; Indomethacin; Intestinal Diseases; Intestine, | 1969 |
Synthesis and pharmacology of a new potential anti-inflammatory drug, 1-(3',4'-methylenedioxybenzoyl)-2-methyl-5-methoxy-3-indolylacetic acid (ID-955).
Topics: Acetates; Analgesics; Animals; Anti-Inflammatory Agents; Blood Proteins; Capillary Permeability; Car | 1969 |