Page last updated: 2024-10-29

indomethacin and Premenstrual Syndrome

indomethacin has been researched along with Premenstrual Syndrome in 3 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Premenstrual Syndrome: A combination of distressing physical, psychologic, or behavioral changes that occur during the luteal phase of the menstrual cycle. Symptoms of PMS are diverse (such as pain, water-retention, anxiety, cravings, and depression) and they diminish markedly 2 or 3 days after the initiation of menses.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gallo, MA1
Smith, SS2
Gong, QH1
Hsu, FC1
Markowitz, RS1
ffrench-Mullen, JM1
Li, X1
Sanz, ML1
Godfrey, C1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dienogest Versus Luteal Phase Fluoxetine in the Management of Premenstrual Syndrome: A Randomized Double Blind Placebo Controlled Trial[NCT02427334]Phase 3210 participants (Anticipated)Interventional2015-04-30Recruiting
The Synergistic Use of Combined Oral Contraceptives and Fluoxetine Versus Combined Oral Contraceptives in the Management of Severe Premenstrual Syndrome: A Randomized Double Blind Placebo Controlled Trial[NCT02488538]Phase 3300 participants (Anticipated)Interventional2015-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for indomethacin and Premenstrual Syndrome

ArticleYear
Progesterone withdrawal decreases latency to and increases duration of electrified prod burial: a possible rat model of PMS anxiety.
    Pharmacology, biochemistry, and behavior, 1993, Volume: 46, Issue:4

    Topics: Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Diazepam; Disease Models, Animal; Electrosh

1993
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
    Nature, 1998, Apr-30, Volume: 392, Issue:6679

    Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Carbolines; Female; gamma-Aminobutyric Acid;

1998
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
    Nature, 1998, Apr-30, Volume: 392, Issue:6679

    Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Carbolines; Female; gamma-Aminobutyric Acid;

1998
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
    Nature, 1998, Apr-30, Volume: 392, Issue:6679

    Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Carbolines; Female; gamma-Aminobutyric Acid;

1998
GABA(A) receptor alpha4 subunit suppression prevents withdrawal properties of an endogenous steroid.
    Nature, 1998, Apr-30, Volume: 392, Issue:6679

    Topics: Animals; Anti-Anxiety Agents; Azides; Benzodiazepines; Carbolines; Female; gamma-Aminobutyric Acid;

1998
Ischemic heart disease: part of the premenstrual syndrome?
    American heart journal, 1985, Volume: 110, Issue:3

    Topics: Adult; Angina Pectoris; Female; Humans; Indomethacin; Myocardial Infarction; Premenstrual Syndrome;

1985