indomethacin has been researched along with Premature Rupture of Fetal Membranes in 11 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our aim was to estimate if indomethacin therapy prevents preterm birth (PTB) in women with a short cervical length (CL) on transvaginal ultrasound (TVU)." | 8.83 | Short cervix on ultrasound: does indomethacin prevent preterm birth? ( Althuisius, SM; Berghella, V; Rust, OA, 2006) |
| "The purpose of this study was to estimate the effect of indomethacin on the prevention of preterm birth (PTB) in women with an ultrasound-indicated cerclage." | 7.74 | Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth? ( Airoldi, J; Berghella, V; Visintine, J, 2008) |
| "Our aim was to estimate if indomethacin therapy prevents preterm birth (PTB) in women with a short cervical length (CL) on transvaginal ultrasound (TVU)." | 4.83 | Short cervix on ultrasound: does indomethacin prevent preterm birth? ( Althuisius, SM; Berghella, V; Rust, OA, 2006) |
| " Magnesium sulfate administration, steroid administration, maternal diabetes mellitus, gestational age at delivery, indomethacin exposure, birthweight, and chorioamnionitis were all considered as possible covariates in the multivariable regression models." | 3.83 | Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. ( DeWitt, PE; Faucett, AM; Gibbs, RS; Metz, TD, 2016) |
| "The purpose of this study was to estimate the effect of indomethacin on the prevention of preterm birth (PTB) in women with an ultrasound-indicated cerclage." | 3.74 | Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth? ( Airoldi, J; Berghella, V; Visintine, J, 2008) |
| "Indomethacin has been tested, in addition to betasympathicomimetic therapy, in cases with an insufficient inhibition of premature labour." | 1.27 | Inhibition of premature labour with indomethacin. ( Halle, H, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Emeruwa, UN | 1 |
| Krenitsky, NM | 1 |
| Sheen, JJ | 1 |
| Zanardini, C | 1 |
| Pagani, G | 1 |
| Fichera, A | 1 |
| Prefumo, F | 1 |
| Frusca, T | 1 |
| Faucett, AM | 1 |
| Metz, TD | 1 |
| DeWitt, PE | 1 |
| Gibbs, RS | 1 |
| Ventolini, G | 1 |
| Genrich, TJ | 1 |
| Roth, J | 1 |
| Neiger, R | 1 |
| Ehsanipoor, RM | 1 |
| Shrivastava, VK | 1 |
| Lee, RM | 1 |
| Chan, K | 1 |
| Galyean, AM | 1 |
| Garite, TJ | 1 |
| Rumney, PJ | 1 |
| Wing, DA | 1 |
| Berghella, V | 2 |
| Rust, OA | 1 |
| Althuisius, SM | 1 |
| Visintine, J | 1 |
| Airoldi, J | 1 |
| Van Overmeire, B | 1 |
| Slootmaekers, V | 1 |
| De Loor, J | 1 |
| Buytaert, P | 1 |
| Hagendorens, M | 1 |
| Sys, SU | 1 |
| Van Reempts, PJ | 1 |
| Spearing, G | 1 |
| Fuller, WE | 1 |
| Halle, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Control Trial Physical Exam Indicated Cerclage in Twin Gestations[NCT02490384] | 30 participants (Actual) | Interventional | 2015-06-30 | Terminated (stopped due to due to significant decrease of perinatal mortality in the cerclage group) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for indomethacin and Premature Rupture of Fetal Membranes
| Article | Year |
|---|---|
Advances in Management for Preterm Fetuses at Risk of Delivery.
Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Prema | 2020 |
Short cervix on ultrasound: does indomethacin prevent preterm birth?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cervix Uteri; Female; Fetal Membranes, Premature Rupture; H | 2006 |
1 trial available for indomethacin and Premature Rupture of Fetal Membranes
| Article | Year |
|---|---|
A randomized, double-masked trial of prophylactic indomethacin tocolysis versus placebo in women with premature rupture of membranes.
Topics: Adult; Double-Blind Method; Early Termination of Clinical Trials; Female; Fetal Membranes, Premature | 2011 |
8 other studies available for indomethacin and Premature Rupture of Fetal Membranes
| Article | Year |
|---|---|
Cervical cerclage in twin pregnancies.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cerclage, Cervical; Cervix Uteri; Female; Feta | 2013 |
Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Birth Weight; Case-Control Studies; Cerebral Hemorrhage; | 2016 |
Pregnancy outcome after placement of 'rescue' Shirodkar cerclage.
Topics: Adolescent; Adult; Bed Rest; Cerclage, Cervical; Cohort Studies; Combined Modality Therapy; Female; | 2009 |
Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cerclage, Cervical; Cervical Length Measurement; Cer | 2008 |
The addition of indomethacin to betamimetics for tocolysis: any benefit for the neonate?
Topics: Adrenergic beta-Agonists; Bronchopulmonary Dysplasia; Cohort Studies; Female; Fetal Membranes, Prema | 1998 |
Alcohol, indomethacin, and salbutamol. A comparative trial of their use in preterm labor.
Topics: Albuterol; Birth Weight; Drug Therapy, Combination; Ethanol; Female; Fetal Membranes, Premature Rupt | 1979 |
Management of premature labor.
Topics: Aspirin; Bed Rest; Betamethasone; Estrogens; Ethanol; Female; Fetal Membranes, Premature Rupture; Gl | 1978 |
Inhibition of premature labour with indomethacin.
Topics: Female; Fetal Membranes, Premature Rupture; Humans; Indomethacin; Infant, Low Birth Weight; Infant, | 1987 |