indomethacin has been researched along with Pregnancy in 1320 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Further studies are needed to determine whether any dose adjustments are necessary as a result of the increased clearance of indomethacin during pregnancy." | 9.19 | Pharmacokinetics of indomethacin in pregnancy. ( Abdel-Rahman, SM; Ahmed, MS; Caritis, SN; Clark, SM; Cochran, M; Hankins, GD; Nanovskaya, TN; Rytting, E; Venkataramanan, R; Vernikovskaya, DI; Wang, X, 2014) |
| "The postoperative analgesic effects of rectal indomethacin and tramadol were compared in patients undergoing elective termination of first trimester pregnancy and diagnostic dilatation and curettage." | 9.15 | Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy. ( Debby, A; Evron, S; Ezri, T; Golan, A; Khazin, V; Rozenzvit-Podles, E; Weitzman, S, 2011) |
| "The use of indomethacin as a tocolytic agent for preterm labor is associated with an increased risk for severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia." | 8.91 | Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis. ( Hammers, AL; Kaunitz, AM; Sanchez-Ramos, L, 2015) |
| "Our aim was to estimate if indomethacin therapy prevents preterm birth (PTB) in women with a short cervical length (CL) on transvaginal ultrasound (TVU)." | 8.83 | Short cervix on ultrasound: does indomethacin prevent preterm birth? ( Althuisius, SM; Berghella, V; Rust, OA, 2006) |
| "It appears that maternal indomethacin therapy may be a useful adjunct in selected cases of polyhydramnios." | 8.78 | Indomethacin therapy in the treatment of symptomatic polyhydramnios. ( Moise, KJ, 1991) |
| "To determine if intestinal perforations before 14 days (either spontaneous (SIP) or necrotizing enterocolitis-induced) are increased when infants who received antenatal betamethasone shortly before birth are treated with prophylactic indomethacin (PINDO)." | 8.31 | Prophylactic indomethacin, antenatal betamethasone, and the risk of intestinal perforation in infants <28 weeks' gestation. ( Clyman, RI; Hills, NK, 2023) |
| "To estimate if the odds of spontaneous intestinal perforation (SIP) are increased when antenatal steroids (ANS) given close to delivery are combined with indomethacin on day 1 after birth (Indo-D1)." | 8.31 | Antenatal Steroids, Prophylactic Indomethacin, and the Risk of Spontaneous Intestinal Perforation. ( Arnautovic, TI; Brion, LP; Chowdhury, D; Das, A; Keszler, M; Laptook, AR; Oh, W; Weydig, H; Wyckoff, MH; Younge, N, 2023) |
| "To evaluate the efficacy of long-term indomethacin therapy (LIT) in prolonging pregnancy and reducing spontaneous preterm birth (PTB) in patients undergoing fetoscopic laser surgery (FLS) for the management of twin-to-twin transfusion syndrome (TTTS)." | 8.12 | Efficacy of long-term indomethacin therapy in prolonging pregnancy after fetoscopic laser surgery for twin-to-twin transfusion syndrome: a collaborative cohort study. ( Belfort, MA; Cortes, MS; Donepudi, R; Espinoza, J; Harman, C; Krispin, E; Mustafa, HJ; Nassr, AA; Pederson, N; Shamshirsaz, AA; Tadbiri, H; Turan, OM, 2022) |
| "Indomethacin is used for the treatment of preterm labour, short cervices and idiopathic polyhydramnios during pregnancy." | 8.12 | Prediction of maternal and fetal pharmacokinetics of indomethacin in pregnancy. ( Ahmed, MS; Caritis, SN; Clark, SM; Hankins, GDV; Nanovskaya, TN; Pillai, VC; Rytting, E; Shah, M; Venkataramanan, R; Wang, X, 2022) |
| "To determine if antenatal variables affect the risk of spontaneous intestinal perforation (SIP) among preterm infants when prophylactic indomethacin is used." | 8.02 | Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin. ( Arnautovic, TI; Keszler, M; Laptook, AR; Longo, JL; Trail-Burns, EJ; Tucker, R, 2021) |
| "To evaluate the association of a combined exposure to antenatal steroids and prophylactic indomethacin with the outcome of spontaneous intestinal perforation (SIP) among neonates born at <26 weeks of gestation or <750 g birth weight." | 8.02 | Association of Co-Exposure of Antenatal Steroid and Prophylactic Indomethacin with Spontaneous Intestinal Perforation. ( Adie, MA; Daspal, S; Dorling, J; Kandraju, H; Kanungo, J; Lee, KS; Lee, SK; Shah, PS; Ye, XY, 2021) |
| "Postnatal indomethacin is reportedly associated with an increased incidence of necrotizing enterocolitis (NEC) in preterm infants." | 7.77 | The risk of necrotizing enterocolitis after indomethacin tocolysis. ( Holzhausen, KA; Kellogg, H; Lulic-Botica, M; Pruder, S; Salari, V; Sood, BG; Thomas, R, 2011) |
| "Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal." | 7.76 | Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010) |
| "We sought to estimate the effect of indomethacin on duration of pregnancy in women with dilated cervix between 14 (0)/ (7) to 25 (6)/ (7) weeks." | 7.75 | Does indomethacin prevent preterm birth in women with cervical dilatation in the second trimester? ( Berghella, V; Chaithongwongwatthana, S; Cotter, A; Gomez, R; Kearney, E; Mittal, S; Pereira, L; Prasertcharoensuk, W; Rasanen, J; Tolosa, JE, 2009) |
| "The purpose of this study was to estimate the effect of indomethacin on the prevention of preterm birth (PTB) in women with an ultrasound-indicated cerclage." | 7.74 | Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth? ( Airoldi, J; Berghella, V; Visintine, J, 2008) |
| "Although the association between oligohydramnios and indomethacin use for premature labor has been well known for many years, there have been few cases published about it." | 7.72 | Acute severe reversible oligohydramnios induced by indomethacin in a patient with rheumatoid arthritis: a case report and review of the literature. ( Ermiş, H; Has, R; Ibrahimoğlu, L; Topuz, S; Yildirim, A; Yüksel, A, 2004) |
| "To evaluate the effects of an increase in glucose infusion rate of 2 mg/kg per min from the basal infusion rate on the prevention of hypoglycemia in very low-birthweight (VLBW) infants, following indomethacin therapy for patent ductus arteriosus (PDA)." | 7.71 | Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus. ( Hosono, S; Kimoto, H; Nagoshi, R; Nozawa, M; Ohono, T; Shimizu, M, 2001) |
| "One objective of this experiment was to evaluate our hypotheses that estradiol-17beta regulates secretion of pregnancy specific protein B (PSPB) and that secretion of progesterone during pregnancy is regulated by a prostanoid by examining the effects of prostaglandin F2alpha (PGF2alpha), a luteolyic agent; indomethacin, a prostanoid synthesis inhibitor; tamoxifen, an estrogen receptor antagonist; estradiol 17-beta; and interaction of these factors on the incidence of abortion and progesterone and PSPB secretion." | 7.70 | Effect of PGF2alpha, indomethacin, tamoxifen, or estradiol-17beta on incidence of abortion, progesterone, and pregnancy-specific protein B (PSPB) secretion in 88- to 90-day pregnant sheep. ( Bridges, PJ; Kim, LM; LeaMaster, BR; Sasser, RG; Vincent, DL; Weems, CW; Weems, YS, 1999) |
| "To investigate the possible association of indomethacin tocolysis with neonatal necrotizing enterocolitis." | 7.70 | Indomethacin tocolysis and risk of necrotizing enterocolitis. ( Dooley, SL; Grobman, WA; Holtzman, RB; Parilla, BV; Thomas, HA, 2000) |
| "Long-term indomethacin treatment during pregnancy may lead to the development of renal failure and irreversible renal damage with cystic dilatation of developing nephrons in an exposed fetus." | 7.69 | Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin. ( Bavoux, F; Carlus, C; Delezoide, AL; Gubler, MC; Narcy, F; van der Heijden, BJ, 1994) |
| "This study characterises the reactivity of chorionic plate artery in pre-eclampsia to prostaglandin F2 alpha (PGF2 alpha), 5-hydroxytryptamine (5-HT), and potassium chloride (KCl) and examines the role of the vascular endothelium in these responses." | 7.69 | The role of the vascular endothelium in the contractile responses of human chorionic plate artery in pre-eclampsia to prostaglandin F2 alpha, 5-hydroxytryptamine, and potassium chloride. ( Aloamaka, CP; Ezimokhai, M; Mensah-Brown, EP; Morrison, J; Osman, NA, 1995) |
| "A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described." | 7.69 | In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale. ( Achiron, R; Berant, M; Hegesh, J; Kidron, D; Lipitz, S; Rotstein, Z, 1996) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 7.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "5 mg/kg per day of indomethacin for polyhydramnios are reported." | 7.68 | Efficacy and safety of indomethacin therapy for polyhydramnios. ( Cararach, V; Carmona, F; Iglesias, X; Martínez-Román, S; Mortera, C; Puerto, B, 1993) |
| " Nineteen pregnant rats, un-treated and treated with Indomethacin (3 mg/kg body/wt) for 4 days during peak glomerular hyperfiltration, were studied before and during pregnancy." | 7.68 | Chronic indomethacin administration and its relation with the renal kallikrein kinin system during rat pregnancy. ( Arrizurieta, EE; Martín, RS; Negri, AL; Oddo, EM; Santos, JC, 1993) |
| "Eighteen pregnant women were given indomethacin during the year 1989 for treatment of premature labor (n = 16) or polyhydramnios (n = 2)." | 7.68 | [Maternal and neonatal effects of indomethacin administrated during pregnancy. Apropos of 18 cases]. ( Bavoux, F; Blot, P; Boissinot, C; Guillonneau, M; Hartmann, JF; Jacqz-Aigrain, E, 1993) |
| " We retrospectively reviewed seven cases of degenerating fibroids complicating pregnancy where the prostaglandin synthetase inhibitor, indomethacin (25 mg orally every 6 hours), was used to treat symptoms of pain." | 7.68 | Indomethacin for the treatment of symptomatic leiomyoma uteri during pregnancy. ( Carpenter, RJ; Dildy, GA; Kirshon, B; Moise, KJ; Smith, LG, 1992) |
| "Prenatal administration of indomethacin for the treatment of polyhydramnios at 27 weeks' gestation resulted in the rapid restoration of normal amniotic fluid volume." | 7.68 | Indomethacin for the treatment of polyhydramnios: a case of constriction of the ductus arteriosus. ( D'Orsogna, L; Mohen, D; Newnham, JP, 1992) |
| "Indomethacin has been used in twins with polyhydramnios to decrease amniotic fluid volume." | 7.68 | Indomethacin therapy and fetal urine production in twins with polyhydramnios. ( Beyth, Y; Fejgin, MD; Rabinowitz, R; Regev, RH; Rosen, DJ, 1991) |
| "The Authors report their experience of two pregnancies complicated by polyhydramnios, treated with indomethacin (100 mg/day for 10 and 7 days respectively)." | 7.68 | [Use of indomethacin in the therapy of poly-hydramnios. Description and comments on a case]. ( Giordano, A; Moscolo, G; Toppano, B; Zardini, E, 1991) |
| "A case is reported in which exposure to cocaine and indomethacin was associated with development of fetal anuria, anasarca, and neonatal gastrointestinal hemorrhage." | 7.68 | Cocaine and indomethacin: fetal anuria, neonatal edema, and gastrointestinal bleeding. ( Angel, JL; Carlan, SJ; Harris, M; O'Brien, WF; Stromquist, C, 1991) |
| "Fifteen patients with polyhydramnios and clinical symptoms related to excess amniotic fluid volume were treated with indomethacin therapy that was started at a mean gestational age of 27." | 7.68 | Maternal indomethacin therapy in the treatment of polyhydramnios. ( Andreou, A; Assimakopoulos, E; Mamopoulos, M; Mantalenakis, S; Reece, EA; Zheng, XZ, 1990) |
| "Ten pregnancies with 13 fetuses complicated by symptomatic polyhydramnios were treated with indomethacin." | 7.68 | Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ; Wasserstrum, N, 1990) |
| "A case of polyhydramnios was effectively treated with amniotic fluid decompression and indomethacin." | 7.68 | Indomethacin treatment for polyhydramnios and subsequent infantile nephrogenic diabetes insipidus. ( Cotton, DB; Kirshon, B; Smith, LG, 1990) |
| "A case of recurrent acute polyhydramnios successfully treated with indomethacin is described." | 7.68 | [Recurrent acute polyhydramnios treated with indomethacin]. ( Faber, BL, 1990) |
| "The purpose of this study was to determine whether indomethacin alters the maternal and fetal hemodynamic response to magnesium sulfate (MgSO4) infusion and hemorrhage in gravid ewes." | 7.68 | Does indomethacin alter the hemodynamic response to magnesium sulfate infusion and hemorrhage in gravid ewes? ( Chestnut, DH; DeBruyn, CS; Thompson, CS; Weiner, CP, 1990) |
| "Little is known about the placental transfer of indomethacin in the human pregnancy." | 7.68 | Placental transfer of indomethacin in the human pregnancy. ( Cano, LE; Carpenter, RJ; Kirshon, B; Moise, KJ; Ou, CN; Rognerud, C, 1990) |
| "To investigate the effects of indomethacin on the human fetal renal blood flow velocity waveform, 17 fetuses whose mothers were treated for preterm labor (N = 8) or polyhydramnios (N = 9) were studied." | 7.68 | Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios. ( Carpenter, RJ; Deter, RL; Kirshon, B; Mari, G; Moise, KJ, 1990) |
| "Eight gravidas with symptomatic polyhydramnios were managed with maternal indomethacin therapy." | 7.68 | Indomethacin therapy in the treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ, 1990) |
| "Indomethacin was administered to suppress premature uterine contractions in a twin pregnancy from the 27th until the 32nd week of pregnancy." | 7.67 | Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report. ( Abramovici, H; Atad, J; Lissak, A; Rofe, A, 1987) |
| " Inhibition of prostaglandin (PG) synthesis by indomethacin (Id) during early pregnancy in rabbits apparently disrupts the process of sex steroid production by the ovaries." | 7.67 | Effect of indomethacin on plasma levels of vitamin D metabolites, oestradiol and progesterone in rabbits during early pregnancy. ( el-Banna, AA; Sedrani, SH, 1987) |
| " We took advantage of the treatment of pregnant women with indomethacin, because of premature labor or hydramnios, to investigate the role of prostaglandins in the activation of T suppressor (TS) activity." | 7.67 | The effects of indomethacin administration during pregnancy on women's and newborns' T-suppressor lymphocyte activity and on HLA class II expression by newborns' leukocytes. ( Brami, C; Durandy, A; Griscelli, C, 1985) |
| " In experiment 3, conceptuses were recovered on days 16, 20 and 24 of pregnancy and incubated with [3H] AA to determine the effects of indomethacin on [3H] AA metabolism." | 7.67 | Metabolism of arachidonic acid in vitro by ovine conceptuses recovered during early pregnancy. ( Lewis, GS; Waterman, RA, 1985) |
| "A pregnancy during which both beta-adrenergics and indomethacin were administered in order to stop preterm uterine contractions is reported." | 7.66 | Indomethacin and the fetal renal nonfunction syndrome. ( de Jong, PA; van Wijck, JA; Veersema, D, 1983) |
| "Pregnant gilts (3/group) were given no treatment, 10 mg bromocriptine twice daily by mouth, from Day 111 of pregnancy to 1 day post partum, 25 mg progesterone s." | 7.66 | Plasma concentrations of prolactin, progesterone, relaxin and oestradiol-17 beta in sows treated with progesterone, bromocriptine or indomethacin during late pregnancy. ( Bevers, M; Bradshaw, JM; Dieleman, SJ; Porter, DG; Taverne, M; Willemse, AH, 1982) |
| " The effects of acetaminophen in pregnancy and in the newborn have not been studied extensively; when ingested in usual therapeutic doses, the available data have shown no adverse effects." | 7.66 | Effects of aspirin and acetaminophen in pregnancy and in the newborn. ( Rudolph, AM, 1981) |
| "Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia." | 7.66 | [Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980) |
| "Pregnant women destined to develop pregnancy-induced hypertension (PIH) lose refractoriness to the pressor effects of infused angiotensin II (A-II) several weeks before the onset of hypertension." | 7.66 | Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "Indomethacin was administered during the luteal phase of the menstrual cycle and during late pregnancy in rhesus monkeys." | 7.65 | Effects of indomethacin on corpus luteum function and pregnancy in rhesus monkeys. ( Manaugh, LC; Novy, MJ, 1976) |
| "75 mg/day); phenylbutazone (20 mg/day); flufenamic acid (10 mg/day); and Compound 83161 (tetrazolo less than 1,5-alpha greater than s-triazolo less than 3,4-c greater than quinoxoline) (8 mg/day and 12 mg/day) were each given to intact rats during early pregnancy (days 1 and/or 2 through day 8)." | 7.65 | Studies on the effects of pharmacologic doses of cortisone acetate and several nonsteroidal anti-inflammatory compounds on ovo-implantation, early pregnancy, and the deciduomal response in the rat. ( Bennett, DR; Cochrane, RL; Powell, JG; Rathmacher, RP; Shaar, CJ; Smalstig, EB, 1977) |
| "Preterm birth is the most common cause of neonatal morbidity and mortality." | 7.01 | The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol. ( Abdelrahiem, SK; Adam, I; Elfaki, T; Elhassan, EM; Ibrahim, MH, 2021) |
| "Cerebral palsy was found in 36 (9." | 6.68 | Antecedents of cerebral palsy in a multicenter trial of indomethacin for intraventricular hemorrhage. ( Allan, WC; Katz, KH; Makuch, RW; Ment, LR; Vohr, B, 1997) |
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 6.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| "Indomethacin has been shown to reduce amniotic fluid volume in certain cases, but a strict monitoring schedule should be followed whenever it is administered." | 6.39 | Treatment of polyhydramnios with indomethacin. ( Kirshon, B; Kramer, WB; Van den Veyver, IB, 1994) |
| "When Indomethacin in a dosage of 175 mg/day was used to treat threatened premature labour more than 70% of cases carried on until 37 weeks." | 6.37 | [Value and dangers of indomethacin used in pregnancy. Apropos of 304 treated patients]. ( Barrat, J; Bouillie, J; Boyer, F; Keskes, J; Marpeau, L; Pigné, A; Vincenti, O, 1988) |
| " The concentration of ETV in the liver was not obviously altered during pregnancy, which indicates that dosage adjustment in pregnancy is not necessary." | 5.51 | Roles of organic anion transporter 2 and equilibrative nucleoside transporter 1 in hepatic disposition and antiviral activity of entecavir during non-pregnancy and pregnancy. ( Bai, M; Jiang, H; Jiang, T; Lin, N; Lu, S; Ma, Z; Sun, D; Zeng, S; Zhou, H, 2019) |
| " Our PBPK/PD model suggested a higher indomethacin dosing requirement during pregnancy." | 5.42 | Development of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in Pregnancy. ( Alqahtani, S; Kaddoumi, A, 2015) |
| " Indomethacin was superior to celecoxib for pain score at rest at 8-12 h and celecoxib + parecoxib, diclofenac, and ketorolac for pain score on movement at 48 h." | 5.41 | Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis. ( Blake, L; Carvalho, B; Carver, AL; Desai, N; Murdoch, I; O'Carroll, JE; Onwochei, DN; Sultan, P, 2023) |
| "Indomethacin has been also used in women with short cervices as well as in those with idiopathic polyhydramnios." | 5.38 | Indomethacin in pregnancy: applications and safety. ( Abou-Ghannam, G; Nassar, AH; Usta, IM, 2012) |
| "In women with twin pregnancies and asymptomatic cervical dilation before 24 weeks of gestation, a combination of physical examination-indicated cerclage, indomethacin, and antibiotics significantly decreased preterm birth at all evaluated gestational ages." | 5.34 | Physical examination-indicated cerclage in twin pregnancy: a randomized controlled trial. ( Berghella, V; Colihan, S; Gimovsky, AC; Haeri, S; Roman, A; Saccone, G; Schoen, CN; Seligman, NS; Zelig, C; Zork, N; Zullo, F, 2020) |
| "Pregnancy is associated with a significant increase in uterine blood flow which contributes to optimal fetal development." | 5.31 | Pregnancy is associated with altered response to neuropeptide Y in uterine artery. ( Grbovic, L; Jovanovic, A; Jovanovic, S, 2000) |
| "Success rate correcting symptomatic polyhydramnios with Indomethacin was 100%." | 5.30 | [Pregnancy complicated with symptomatic polyhydramnios: treatment with indomethacin]. ( Campos-Rivera, P; Lasso-de la Vega, J; Vigil-de Gracia, PE, 1997) |
| "A condition similar to preeclampsia was induced by infusing pregnant rats with the nitric oxide synthase inhibitor N G -nitro- L -arginine methyl ester through subcutaneously implanted osmotic minipumps." | 5.30 | The effect of indomethacin and prostacyclin agonists on blood pressure in a rat model of preeclampsia. ( Buhimschi, I; Chwalisz, K; Garfield, RE; Liao, QP; Saade, GR; Zlatnik, MG, 1999) |
| "Indomethacin was discontinued beyond the 33rd week of gestational age." | 5.29 | [Has the use of indomethacin during pregnancy consequences in newborn infants? Prospective study of 83 pregnant women and 115 newborn infants]. ( Blot, P; Boissinot, C; Carbillon, L; de Gayffier, A; Germain, JF; Jacqz-Aigrain, E; Oury, JF; Sibony, O, 1994) |
| "Pretreatment with indomethacin did not result in improved fetal survival." | 5.29 | A rabbit model for ascending infection in pregnancy: intervention with indomethacin and delayed ampicillin-sulbactam therapy. ( Gibbs, RS; Heddleston, L; McDuffie, RS, 1993) |
| "Indomethacin was given at a dose of 3 mg/kg/day." | 5.29 | Treatment of symptomatic polyhydramnios with indomethacin. ( Cabrol, D; Jannet, D; Pannier, E, 1996) |
| "Indomethacin is a potent tocolytic agent used in premature labor." | 5.28 | Oligohydramnios induced by maternal indomethacin therapy. ( Aydin, C; Ozcan, FS; Uslu, T, 1992) |
| "Among the difficulties encountered, premature labor and polyhydramnios are common." | 5.28 | Indomethacin therapy and chronic hemodialysis during pregnancy. A case report. ( Dolkart, LA; Eshwar, KP; Reimers, FT, 1992) |
| "The vasodilation of pregnancy is thought by many to be due to increased endothelial production of prostacyclin, a vasodilatory prostanoid." | 5.28 | The maternal hemodynamic effect of indomethacin in normal pregnancy. ( Benedetti, TJ; Brateng, DA; Carlson, KL; Easterling, TR; Sorensen, TK, 1992) |
| "Indomethacin was used for tocolysis and to maintain mild oligohydraminios (amniotic fluid index 5-7 cm)." | 5.28 | Intraoperative amniocentesis and indomethacin treatment in the management of an immature pregnancy with completely dilated cervix. ( Evans, DJ; King, K; Kofinas, AD, 1992) |
| "Provided that preeclampsia comprises enhanced vascular actions of thromboxane A2, the present results support the established use of Mg++ in the treatment of this condition and suggest that calcium antagonists are of potential benefit." | 5.28 | Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy. ( Andersson, KE; Forman, A; Skajaa, K; Svane, D, 1990) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 5.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| "A case of polyhydramnios associated with a ring chromosome is described." | 5.27 | Polyhydramnios associated with a ring chromosome and low maternal serum alpha-fetoprotein levels managed with indomethacin. ( Cotton, DB; Kirshon, B, 1988) |
| "Despite the reduction in leukocytosis, implantation was prevented by the high dose of indomethacin." | 5.27 | Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat. ( Hurst, PR; Peplow, PV, 1985) |
| "Indomethacin purportedly arrests premature labor by inhibiting the production of prostaglandins." | 5.26 | Possible association between maternal indomethacin therapy and primary pulmonary hypertension of the newborn. ( Manchester, D; Margolis, HS; Sheldon, RE, 1976) |
| "Indomethacin treatment at the time of implantation interfered with pregnancy and caused degeneration and resorption of embryos." | 5.26 | Effect of indomethacin on egg transport and pregnancy in the rabbit. ( El-Banna, AA; Sacher, B; Schilling, E, 1976) |
| "Treatment with indomethacin significantly prolonged the length of gestation (P smaller than 0-01) compared iwth control, untreated animals." | 5.25 | The effects of dexamethasone and indomethacin on the outcome of pregnancy in the rabbit. ( Challis, JR; Davies, IJ; Ryan, KJ, 1975) |
| "Nifedipine may be better for delayed delivery and less likely to produce adverse pregnancy outcomes, followed by indomethacin." | 5.22 | Four kinds of tocolytic therapy for preterm delivery: Systematic review and network meta-analysis. ( Pei, S; Xiong, Z; Zhu, Z, 2022) |
| "The postoperative analgesic effects of rectal indomethacin and tramadol were compared in patients undergoing elective termination of first trimester pregnancy and diagnostic dilatation and curettage." | 5.15 | Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy. ( Debby, A; Evron, S; Ezri, T; Golan, A; Khazin, V; Rozenzvit-Podles, E; Weitzman, S, 2011) |
| "Thirty patients with a low-risk pregnancy, gestational age 26 to 32 weeks, and no signs of preterm labor were randomly assigned to receive either terbutaline (5 mg), indomethacin (50 mg), or a placebo." | 5.07 | The effect of tocolytic agents (indomethacin and terbutaline) on fetal breathing and body movements: a prospective, randomized, double-blind, placebo-controlled clinical trial. ( Cotton, DB; Dorman, KF; Hallak, M; Lira, N; Moise, K; Smith, EO, 1992) |
| "5 mg 15(S) 15 methyl PGF2 alpha (15 me PGF2 alpha) in terminating mid-trimester pregnancy in 10 subjects has been compared with the effect of the same medication given to 10 others who had had indomethacin 25 mg and 50 mg orally three and one hour before the PG administration." | 5.06 | Effect of indomethacin on the injection-abortion interval of 15(S) 15 methyl PGF2 alpha-induced mid-trimester abortions--a randomized study. ( Adaikan, PG; Kottegoda, SR; Prasad, RN; Ratnam, SS, 1987) |
| " Moderate certainty evidence showed a reduction in NEC following administration of a combination of species of probiotics, probiotics (any), antenatal corticosteroids in pregnant women at risk of preterm birth, and ibuprofen versus indomethacin for treatment of patent ductus arteriosus (PDA)." | 5.05 | An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants. ( Ei-Saie, A; Maheshwari, A; Neu, J; Pammi, M; Xiong, T, 2020) |
| "A single-blind, non-crossover study of the effectiveness of paracetamol, compared with aspirin and indomethacin has been carried out in 143 patients suffering from rheumatoid arthritis." | 5.04 | Therapeutic effectiveness of paracetamol in rheumatoid arthritis. ( Anderson, J; Buchanan, W; Lee, P; Watson, M; Webb, J, 1975) |
| "This study was undertaken to determine if post-abortion luteolysis in early pregnancy could be accelerated by the administration of 15(S)15-methyl-PGF2alpha(15-me-PGF2alpha) or delayed following pretreatment with indomethacin." | 5.04 | Prostaglandins and post-abortion luteolysis in early pregnancy. ( Bygdeman, M; Cekan, SZ; Diczfalusy, E; Guerrero, R; Leader, A; Martin, JN; Wiqvist, N, 1975) |
| "The use of indomethacin as a tocolytic agent for preterm labor is associated with an increased risk for severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia." | 4.91 | Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis. ( Hammers, AL; Kaunitz, AM; Sanchez-Ramos, L, 2015) |
| "Antenatal indomethacin may be associated with an increased risk of periventricular leukomalacia and necrotizing enterocolitis in premature infants and therefore should be used judiciously for tocolysis." | 4.84 | Metaanalysis of the effect of antenatal indomethacin on neonatal outcomes. ( Amin, SB; Glantz, JC; Sinkin, RA, 2007) |
| "This review, which summarizes our findings concerning the long-term effects of pre-, peri- and postnatal factors affecting development, nociception and sensorimotor functions, focuses on three areas: 1) perinatal factors influencing nociception in adult rats were examined in rats with hippocampal lesions, after the administration of stress influencing and psychostimulant drugs (dexamethasone, indomethacine and methamphetamine); 2) the effect of pre- and early postnatal methamphetamine administration was shown to impair the development of sensorimotor functions tested in rat pups throughout the preweaning period; 3) the effect of extensive dorsal rhizotomy of the brachial plexus during the early postnatal period was studied with respect to neuropathic pain development and sensorimotor functions." | 4.84 | Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development. ( Franek, M; Hrubá, L; Pometlová, M; Rokyta, R; Schutová, B; Slamberová, R; Vaculín, S; Yamamotová, A, 2008) |
| "Our aim was to estimate if indomethacin therapy prevents preterm birth (PTB) in women with a short cervical length (CL) on transvaginal ultrasound (TVU)." | 4.83 | Short cervix on ultrasound: does indomethacin prevent preterm birth? ( Althuisius, SM; Berghella, V; Rust, OA, 2006) |
| "Clinical trials have demonstrated that most tocolytic agents such as beta mimetics, atosiban and indometacine -exception made for magnesium sulfate- extend the duration of pregnancy, when compared to placebo." | 4.81 | [Tocolysis: indications and contraindications. When to start and when to stop]. ( Boubli, L; Bretelle, F; D'ercole, C; Desbriere, R; Shojai, R, 2002) |
| " Up to the present day, several cases of severe and sometimes irreversible renal insufficiency have been described in neonates exposed to indomethacin prenatally or in the first days of life for treatment of patent ductus arteriosus (PDA)." | 4.81 | NSAID-induced nephrotoxicity from the fetus to the child. ( Cuzzolin, L; Dal Cerè, M; Fanos, V, 2001) |
| "It appears that maternal indomethacin therapy may be a useful adjunct in selected cases of polyhydramnios." | 4.78 | Indomethacin therapy in the treatment of symptomatic polyhydramnios. ( Moise, KJ, 1991) |
| "Three preterm infants exposed antenatally to indomethacin developed a characteristic syndrome consisting of edema and hydrops with a bleeding disorder at birth, oliguric renal failure during the first 3 postnatal days, and acute pneumoperitoneum resulting from localized ileal perforation(s) at the end of the first week of life." | 4.77 | Oligohydramnios, renal insufficiency, and ileal perforation in preterm infants after intrauterine exposure to indomethacin. ( Coppens, M; Cuvelier, C; de Praeter, C; Dhont, M; Govaert, P; Leroy, JG; Thiery, M; Vanhaesebrouck, P, 1988) |
| " D-Penicillamine may be teratogenic thus it should not be commenced during pregnancy and if a patient becomes pregnant whilst receiving the drug, it should be slowly withdrawn or the dosage reduced." | 4.77 | Antirheumatic medication in pregnancy. ( Brooks, PM; Needs, CJ, 1985) |
| " These factors (immaturity, hyperoxia, hypoxia, blood transfusions, intraventricular hemorrhage, apnea, infection, hypercarbia, hypocarbia, patent ductus arteriosus, prostaglandin synthetase inhibitors, vitamin E deficiency, lactic acidosis, prenatal complications, genetic factors) may all be present in an infant." | 4.76 | A reexamination of the role of oxygen in retrolental fibroplasia. ( Dangman, B; Lucey, JF, 1984) |
| "This study aimed to estimate whether a combination of ultrasound-indicated cerclage, indomethacin, and antibiotics in twin pregnancies between 18 and 26 weeks' gestation could extend the pregnancy, reduce the risk for spontaneous preterm birth, and improve perinatal and neonatal outcomes." | 4.31 | Efficacy of ultrasound-indicated cerclage in twin pregnancies: a retrospective case-control study matched by cervical length. ( Chen, C; Li, J; Luo, Q; Lv, M; Qiu, L; Zhao, B, 2023) |
| "To determine if intestinal perforations before 14 days (either spontaneous (SIP) or necrotizing enterocolitis-induced) are increased when infants who received antenatal betamethasone shortly before birth are treated with prophylactic indomethacin (PINDO)." | 4.31 | Prophylactic indomethacin, antenatal betamethasone, and the risk of intestinal perforation in infants <28 weeks' gestation. ( Clyman, RI; Hills, NK, 2023) |
| "To estimate if the odds of spontaneous intestinal perforation (SIP) are increased when antenatal steroids (ANS) given close to delivery are combined with indomethacin on day 1 after birth (Indo-D1)." | 4.31 | Antenatal Steroids, Prophylactic Indomethacin, and the Risk of Spontaneous Intestinal Perforation. ( Arnautovic, TI; Brion, LP; Chowdhury, D; Das, A; Keszler, M; Laptook, AR; Oh, W; Weydig, H; Wyckoff, MH; Younge, N, 2023) |
| "To evaluate the efficacy of long-term indomethacin therapy (LIT) in prolonging pregnancy and reducing spontaneous preterm birth (PTB) in patients undergoing fetoscopic laser surgery (FLS) for the management of twin-to-twin transfusion syndrome (TTTS)." | 4.12 | Efficacy of long-term indomethacin therapy in prolonging pregnancy after fetoscopic laser surgery for twin-to-twin transfusion syndrome: a collaborative cohort study. ( Belfort, MA; Cortes, MS; Donepudi, R; Espinoza, J; Harman, C; Krispin, E; Mustafa, HJ; Nassr, AA; Pederson, N; Shamshirsaz, AA; Tadbiri, H; Turan, OM, 2022) |
| " In this study, PVR was induced in pups in utero by exposure of pregnant dams to indomethacin and hypoxia and cardiac lipids, echocardiographic function and cardiomyocyte mitochondrial function were subsequently examined." | 4.12 | Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups. ( Cole, LK; Dolinsky, VW; Hatch, GM; Sparagna, GC, 2022) |
| " Early indomethacin was associated with a lower risk of patent ductus arteriosus and bronchopulmonary dysplasia and a higher risk of spontaneous intestinal perforation." | 4.12 | Model for severe intracranial hemorrhage and role of early indomethacin in extreme preterm infants. ( Ambalavanan, N; Bell, EF; Carlo, WA; Chawla, S; Chowdhury, D; Das, A; Gantz, M; Harmon, HM; Laptook, AR; Natarajan, G; Shankaran, S; Tapia, JL, 2022) |
| "Our findings suggest that a short course of tocolytic indomethacin does not result in neonatal acute kidney injury." | 4.12 | The Effect of a Short Course of Tocolytic Indomethacin on Urinary Biomarkers in Premature Infants. ( El Samra, A; Guillet, R; Lande, M; Mian, A; Wang, H, 2022) |
| "To determine if antenatal variables affect the risk of spontaneous intestinal perforation (SIP) among preterm infants when prophylactic indomethacin is used." | 4.02 | Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin. ( Arnautovic, TI; Keszler, M; Laptook, AR; Longo, JL; Trail-Burns, EJ; Tucker, R, 2021) |
| "To evaluate the impact of prophylactic indomethacin on early death (<10 days after birth) or severe neurologic injury and on early death or spontaneous intestinal perforation by completed weeks of gestational age in neonates born <29 weeks of gestation." | 4.02 | Gestational Age-Dependent Variations in Effects of Prophylactic Indomethacin on Brain Injury and Intestinal Injury. ( Abdelgadir, D; Afifi, J; Aziz, K; Crossman, SC; Mohammad, K; Piedboeuf, B; Qureshi, M; Shah, PS; Taylor, B; Ye, XY; Yuen, R, 2021) |
| "To evaluate the association of a combined exposure to antenatal steroids and prophylactic indomethacin with the outcome of spontaneous intestinal perforation (SIP) among neonates born at <26 weeks of gestation or <750 g birth weight." | 4.02 | Association of Co-Exposure of Antenatal Steroid and Prophylactic Indomethacin with Spontaneous Intestinal Perforation. ( Adie, MA; Daspal, S; Dorling, J; Kandraju, H; Kanungo, J; Lee, KS; Lee, SK; Shah, PS; Ye, XY, 2021) |
| "Based on data from this study, it can be concluded that indomethacin reduces cycle cancelation due to PO in patients with POR -without compromising implantation and pregnancy rates." | 4.02 | The impact of indomethacin on the number of oocytes retrieved and IVF outcomes in patients with poor ovarian response. ( Oner, G; Sonmezer, M; Tas, M; Yavuz, A, 2021) |
| " To mitigate the extent of CS and allow the pregnancy to continue, maternal non-steroidal anti-inflammatory drug (NSAID) therapy with indomethacin was started at 33 + 5 weeks to induce DA constriction." | 4.02 | Inadvertent irreversible closure of arterial duct following therapeutic use of transplacental indomethacin in a fetus with severe Ebstein's anomaly and circular shunt. ( Arbic, N; Gill, K; Honjo, O; Jaeggi, E; Ryan, G; Seed, M, 2021) |
| " We evaluated the ability of oxytocin receptor-targeted liposomes to localize to uterine tissue in vivo, and assessed if targeted liposomes loaded with indomethacin were capable of preventing lipopolysaccharide-induced preterm birth in mice." | 3.85 | Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor. ( Butler, T; Hua, S; Ilicic, M; Paul, JW; Robertson, S; Smith, R; Tolosa, JM, 2017) |
| " Magnesium sulfate administration, steroid administration, maternal diabetes mellitus, gestational age at delivery, indomethacin exposure, birthweight, and chorioamnionitis were all considered as possible covariates in the multivariable regression models." | 3.83 | Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes. ( DeWitt, PE; Faucett, AM; Gibbs, RS; Metz, TD, 2016) |
| "In the present study, we evaluated the therapeutic value of indomethacin (IDM) and dexamethasone (DXS) on reducing the preterm birth rate in experimental goats after IUBAV." | 3.78 | Protective effects of indomethacin and dexamethasone in a goat model with intrauterine balloon aortic valvuloplasty. ( Hua, Y; Huang, X; Li, Y; Mu, D; Wu, G; Zhao, L; Zhou, K; Zhou, R; Zhu, Q, 2012) |
| " With serial amniocentesis and indomethacin therapy, the pregnancy continued to 36 weeks." | 3.77 | Antenatal Bartter syndrome: a rare cause of unexplained severe polyhydramnios. ( Bhat, YR; Prashanth, KA; Sreelakshmi, K; Vani, R; Vinayaka, G, 2011) |
| "Postnatal indomethacin is reportedly associated with an increased incidence of necrotizing enterocolitis (NEC) in preterm infants." | 3.77 | The risk of necrotizing enterocolitis after indomethacin tocolysis. ( Holzhausen, KA; Kellogg, H; Lulic-Botica, M; Pruder, S; Salari, V; Sood, BG; Thomas, R, 2011) |
| "Close echocardiographic monitoring of fetal Doppler flow velocities is very important after fetal intervention and indomethacin treatment, as the consequences of DA constriction in a fetus with hypoplastic left heart syndrome are potentially lethal." | 3.76 | Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum. ( Benson, CB; Marshall, AC; McElhinney, DB; Silva, V; Tworetzky, W; Vogel, M; Wilkins-Haug, LE, 2010) |
| "We sought to estimate the effect of indomethacin on duration of pregnancy in women with dilated cervix between 14 (0)/ (7) to 25 (6)/ (7) weeks." | 3.75 | Does indomethacin prevent preterm birth in women with cervical dilatation in the second trimester? ( Berghella, V; Chaithongwongwatthana, S; Cotter, A; Gomez, R; Kearney, E; Mittal, S; Pereira, L; Prasertcharoensuk, W; Rasanen, J; Tolosa, JE, 2009) |
| "Our objective was to determine the effect of chorioamnionitis on plasma prostaglandin E2 (PGE2) and thromboxane B2 (TxB2) during the first week in preterm infants." | 3.74 | Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants. ( Aranda, JV; Glibetic, M; Natarajan, G; Thomas, RL, 2008) |
| "The purpose of this study was to describe the fetal and newborn safety profile of prolonged indomethacin treatment during pregnancy." | 3.74 | The safety of prolonged indomethacin therapy. ( Anderson, BL; Savage, AH; Simhan, HN, 2007) |
| "The purpose of this study was to estimate the effect of indomethacin on the prevention of preterm birth (PTB) in women with an ultrasound-indicated cerclage." | 3.74 | Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth? ( Airoldi, J; Berghella, V; Visintine, J, 2008) |
| "In this retrospective study, we tested the following hypotheses: rates of severe intraventricular hemorrhage (SIVH) and early neonatal survival are similar among extremely low birth weight (ELBW) infants treated with combination prophylaxis of phenobarbital and indomethacin compared with phenobarbital alone or no prophylaxis; and rates of patent ductus arteriosus (PDA) and necrotizing enterocolitis (NEC) are similar among indomethacin-exposed and nonexposed ELBW infants." | 3.73 | Combining phenobarbital and indomethacin to improve early neonatal outcomes in the extremely low birth weight infant. ( Ekekezie, II; Mundy, DC; Okah, FA, 2005) |
| " The differential effects of these PDE 3 inhibitors on the near-term and preterm ductus were studied by injecting indomethacin (10 mg/kg) and PDE 3 inhibitors into 21D (21st day of pregnancy: term-21." | 3.73 | In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats. ( Imamura, S; Momma, K; Nakanishi, T; Toyoshima, K, 2006) |
| "To investigate the effect and explore the mechanism of Bushen Antai Recipe (BAR) on pregnancy rate and number of implantation site in blastocyst implantation dysfunction (BID) mice induced by indomethacin." | 3.73 | [Study on regulatory effect of Bushen Antai Recipe on levels of estrogen and progesterone in blastocyst implantation dysfunction mice]. ( Huang, YQ; Zeng, KQ; Zhang, MM, 2006) |
| "To examine whether antenatal steroids (ANS), alone or with early indomethacin, are associated with spontaneous intestinal perforation (SIP)." | 3.73 | New insights into spontaneous intestinal perforation using a national data set (3): antenatal steroids have no adverse association with spontaneous intestinal perforation. ( Attridge, JT; Clark, R; Gordon, PV, 2006) |
| "There were no significant differences between the indomethacin-exposed infants and control infants in birth weight, Apgar scores, frequency of cesarean section deliveries, and multiple gestation." | 3.72 | Neonatal outcome after exposure to indomethacin in utero: a retrospective case cohort study. ( Abbasi, S; Gerdes, JS; Ludmir, J; Samimi, SS; Sehdev, HM, 2003) |
| "Although the association between oligohydramnios and indomethacin use for premature labor has been well known for many years, there have been few cases published about it." | 3.72 | Acute severe reversible oligohydramnios induced by indomethacin in a patient with rheumatoid arthritis: a case report and review of the literature. ( Ermiş, H; Has, R; Ibrahimoğlu, L; Topuz, S; Yildirim, A; Yüksel, A, 2004) |
| "The effects of PGE2, PGF2alpha, trilostane, RU-486, PA, INDO, MER-25, PGE2, or PGF2alpha + PA on secretion of progesterone, PGE2, or PGF2alpha by bovine corpora lutea (CL) of mid-pregnancy in vitro for 4 and 8 hr was examined." | 3.71 | Effects of prostaglandins E2 and F2alpha (PGE2; PGF2alpha), trilostane, mifepristone, palmitic acid (PA), indomethacin (INDO), ethamoxytriphetol (MER-25), PGE2 + PA, or PGF2alpha + PA on PGE2, PGF2alpha, and progesterone secretion by bovine corpora lutea ( Lewis, AW; Randel, RD; Weems, CW; Weems, YS, 2002) |
| "The aim of this study was to investigate the role of nitric oxide in the vasorelaxant effect of magnesium sulfate during pregnancy." | 3.71 | Endothelium dependence and gestational regulation of inhibition of vascular tone by magnesium sulfate in rat aorta. ( Facchinetti, F; Garfield, RE; Jain, V; Longo, M; Saade, GR; Vedernikov, YP, 2001) |
| "To determine the natural history of lung vascular remodeling and cardiac changes in the rat model of persistent pulmonary hypertension syndrome (PPHN) of the newborn, we studied fetal rats subjected to maternal indomethacin administration initiated on day 19 of gestation and continued for 2, 3, or 4 days." | 3.71 | Progressive lung and cardiac changes associated with pulmonary hypertension in the fetal rat. ( Belik, J; Fabris, VE; Pato, MD, 2001) |
| "To investigate the effect of cervical application of nonselective and selective inhibitors of nitric oxide synthases--N-nitro-L-arginine methyl ester, L-N-iminoethyl-lysine, and aminoguanidine--as well as inhibitors of cyclooxygenases--indomethacin, and nimesulide--on timing of delivery and fetal death and disease in pregnant rats." | 3.71 | The effects of cervical application of inhibitors of inducible nitric oxide synthase, cyclooxygenase-1, and cyclooxygenase-2 on delivery in rats. ( Bukowski, R; Garfield, RE; McKay, L; Saade, GR; Shi, SQ, 2001) |
| "To evaluate the effects of an increase in glucose infusion rate of 2 mg/kg per min from the basal infusion rate on the prevention of hypoglycemia in very low-birthweight (VLBW) infants, following indomethacin therapy for patent ductus arteriosus (PDA)." | 3.71 | Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus. ( Hosono, S; Kimoto, H; Nagoshi, R; Nozawa, M; Ohono, T; Shimizu, M, 2001) |
| " Indomethacin therapy from 26 to 31 weeks prevented further progression of polyhydramnios without major side effects." | 3.70 | Prenatal and postnatal management of hyperprostaglandin E syndrome after genetic diagnosis from amniocytes. ( Hensen, P; Köckerling, A; Konrad, M; Leonhardt, A; Seyberth, HW, 1999) |
| "One objective of this experiment was to evaluate our hypotheses that estradiol-17beta regulates secretion of pregnancy specific protein B (PSPB) and that secretion of progesterone during pregnancy is regulated by a prostanoid by examining the effects of prostaglandin F2alpha (PGF2alpha), a luteolyic agent; indomethacin, a prostanoid synthesis inhibitor; tamoxifen, an estrogen receptor antagonist; estradiol 17-beta; and interaction of these factors on the incidence of abortion and progesterone and PSPB secretion." | 3.70 | Effect of PGF2alpha, indomethacin, tamoxifen, or estradiol-17beta on incidence of abortion, progesterone, and pregnancy-specific protein B (PSPB) secretion in 88- to 90-day pregnant sheep. ( Bridges, PJ; Kim, LM; LeaMaster, BR; Sasser, RG; Vincent, DL; Weems, CW; Weems, YS, 1999) |
| "Preterm infants with exposure to antenatal indomethacin might be at increased risk of grade I and II intraventricular haemorrhage and those with both ante- and postnatal exposure at an increased risk of necrotising enterocolitis and sepsis." | 3.70 | Perinatal indomethacin treatment and neonatal complications in preterm infants. ( Ikonen, S; Ojala, R; Tammela, O, 2000) |
| "To investigate the possible association of indomethacin tocolysis with neonatal necrotizing enterocolitis." | 3.70 | Indomethacin tocolysis and risk of necrotizing enterocolitis. ( Dooley, SL; Grobman, WA; Holtzman, RB; Parilla, BV; Thomas, HA, 2000) |
| "Pregnancy lymphocytes were treated with anti-progesterone-induced blocking factor antibody or lipopolysaccharide as a positive control in the presence or absence of indomethacin." | 3.70 | Cyclooxygenase is involved in the effects of progesterone-induced blocking factor on the production of interleukin 12. ( Bartok, B; Par, G; Szekeres-Bartho, J, 2000) |
| "We describe a case of twins with twin-to-twin transfusion syndrome (TTS) who were found to have renal tubular dysgenesis (TRD)-like lesions and hypocalvaria attributed to indomethacin treatment of the mother for acute polyhydramnios." | 3.70 | Renal tubular dysgenesis-like lesions and hypocalvaria. Report of two cases involving indomethacin. ( Dechelotte, P; Lemery, D; Orliaguet, T; Reynaud, P; Robin, YM; Vanlieferingen, P, 2000) |
| "6 weeks of gestation) pregnancy to endothelin-1 (ET-1) and attempts to characterize ET-1 receptor subtype, and the contribution of nitric oxide and cyclooxygenase products in these responses." | 3.70 | Mechanisms of endothelin-1-induced contraction in isolated placental veins from normal full-term and preterm pregnancies. ( Carrasco, G; Cruz, MA; Gallardo, V; González, C; Miguel, P, 2000) |
| "These results support a role for the use of aspirin for antiphospholipid antibody-related pregnancy loss through a mechanism similar to that postulated for preeclampsia, namely, selective inhibition of thromboxane production." | 3.69 | The effect of aspirin and indomethacin on prostacyclin and thromboxane production by placental tissue incubated with immunoglobulin G fractions from patients with lupus anticoagulant. ( Peaceman, AM; Rehnberg, KA, 1995) |
| "Previous studies have shown that epidermal growth factor (EGF) can replace estrogen for initiating embryo implantation in hypophysectomized rats in which pregnancy was maintained with progesterone, provided that uterine trauma preceded the intravenous dose of the growth factor." | 3.69 | The role of arachidonic acid and/or its metabolites in embryo implantation initiated by epidermal growth factor (EGF). ( Chatterjee, S; Johnson, DC, 1995) |
| "Long-term indomethacin treatment during pregnancy may lead to the development of renal failure and irreversible renal damage with cystic dilatation of developing nephrons in an exposed fetus." | 3.69 | Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin. ( Bavoux, F; Carlus, C; Delezoide, AL; Gubler, MC; Narcy, F; van der Heijden, BJ, 1994) |
| "Three cases of neonatal renal insufficiency in very low birthweight (VLBW) infants following repeated antenatal administration of indomethacin to prevent premature labor are reported." | 3.69 | Renal impairment in very low birthweight infants following antenatal indomethacin administration. ( Ichijo, M; Kawaguchi, C; Nakagawa, Y; Nakajima, M; Nishikubo, T; Takahashi, Y; Yoshioka, A, 1994) |
| "This study characterises the reactivity of chorionic plate artery in pre-eclampsia to prostaglandin F2 alpha (PGF2 alpha), 5-hydroxytryptamine (5-HT), and potassium chloride (KCl) and examines the role of the vascular endothelium in these responses." | 3.69 | The role of the vascular endothelium in the contractile responses of human chorionic plate artery in pre-eclampsia to prostaglandin F2 alpha, 5-hydroxytryptamine, and potassium chloride. ( Aloamaka, CP; Ezimokhai, M; Mensah-Brown, EP; Morrison, J; Osman, NA, 1995) |
| "To determine the effect of indomethacin on the amniotic fluid index of individual fetuses in multiple gestations, we evaluated seven sets of twins and two sets of triplets in preterm labor (eight cases) or with polyhydramnios (one case)." | 3.69 | Effect of indomethacin on individual amniotic fluid indices in multiple gestations. ( Hill, LM; Lazebnik, N; Many, A, 1996) |
| "A case of severe fetal congestive heart failure due to occlusion of the ductus arteriosus in a mother treated with indomethacin for polyhydramnios and premature contractions is described." | 3.69 | In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale. ( Achiron, R; Berant, M; Hegesh, J; Kidron, D; Lipitz, S; Rotstein, Z, 1996) |
| "The role of indomethacin-induced peptic ulceration in gastric acid secretion was investigated using albino rats of Wistar strain in early, mid and late pregnancy." | 3.68 | Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats. ( Bolarinwa, Y; Evbuomwan, MI, 1993) |
| "5 mg/kg per day of indomethacin for polyhydramnios are reported." | 3.68 | Efficacy and safety of indomethacin therapy for polyhydramnios. ( Cararach, V; Carmona, F; Iglesias, X; Martínez-Román, S; Mortera, C; Puerto, B, 1993) |
| ""In vitro" isometric developed tension (IDT) and frequency of contractions (FC), glucose (Glu), glycogen (GLY) and triglyceride (TG) metabolism, as well as prostaglandin PGE2 and PGE1 production, were studied in uterine strips and in embryos isolated from controls and diabetic rats at day 10 of pregnancy." | 3.68 | Glucose, glycogen and triglyceride metabolism, as well as prostaglandin production in uterine strips and in embryos from diabetic pregnant rats. Influences of the presence of substrate in the incubation medium. ( Catafau, JR; Gimeno, AL; Gimeno, MA; Gomez, G; Gonzalez, ET; Jawerbaum, A; Rodriguez, RR, 1993) |
| "Eighteen pregnant women were given indomethacin during the year 1989 for treatment of premature labor (n = 16) or polyhydramnios (n = 2)." | 3.68 | [Maternal and neonatal effects of indomethacin administrated during pregnancy. Apropos of 18 cases]. ( Bavoux, F; Blot, P; Boissinot, C; Guillonneau, M; Hartmann, JF; Jacqz-Aigrain, E, 1993) |
| " We retrospectively reviewed seven cases of degenerating fibroids complicating pregnancy where the prostaglandin synthetase inhibitor, indomethacin (25 mg orally every 6 hours), was used to treat symptoms of pain." | 3.68 | Indomethacin for the treatment of symptomatic leiomyoma uteri during pregnancy. ( Carpenter, RJ; Dildy, GA; Kirshon, B; Moise, KJ; Smith, LG, 1992) |
| "Prenatal administration of indomethacin for the treatment of polyhydramnios at 27 weeks' gestation resulted in the rapid restoration of normal amniotic fluid volume." | 3.68 | Indomethacin for the treatment of polyhydramnios: a case of constriction of the ductus arteriosus. ( D'Orsogna, L; Mohen, D; Newnham, JP, 1992) |
| "Indomethacin has been used in twins with polyhydramnios to decrease amniotic fluid volume." | 3.68 | Indomethacin therapy and fetal urine production in twins with polyhydramnios. ( Beyth, Y; Fejgin, MD; Rabinowitz, R; Regev, RH; Rosen, DJ, 1991) |
| "The Authors report their experience of two pregnancies complicated by polyhydramnios, treated with indomethacin (100 mg/day for 10 and 7 days respectively)." | 3.68 | [Use of indomethacin in the therapy of poly-hydramnios. Description and comments on a case]. ( Giordano, A; Moscolo, G; Toppano, B; Zardini, E, 1991) |
| "To determine the relative importance of patent ductus arteriosus, indomethacin, and intestinal distension as factors that promote terminal ileum ischemia, eight near-term fetal lambs were surgically prepared by in situ cannulation of the proximal and distal ends of a loop of terminal ileum, formalin infiltration of the ductus arteriosus, and placement of a snare around the ductus arteriosus to control its patency." | 3.68 | Patent ductus arteriosus, indomethacin, and intestinal distension: effects on intestinal blood flow and oxygen consumption. ( Alpan, G; Clyman, RI; Lin, E; Meyers, RL, 1991) |
| "We report oligohydramnios and renal dysgenesis in one of identical twins, which might have resulted from in utero exposure to early, prolonged high-dose indomethacin." | 3.68 | Renal dysgenesis in a monozygotic twin: association with in utero exposure to indomethacin. ( Kaplan, BS; Kaplan, P; Restaino, I; Roberts, N; Rosenberg, HK; Witzleben, C, 1991) |
| "A case is reported in which exposure to cocaine and indomethacin was associated with development of fetal anuria, anasarca, and neonatal gastrointestinal hemorrhage." | 3.68 | Cocaine and indomethacin: fetal anuria, neonatal edema, and gastrointestinal bleeding. ( Angel, JL; Carlan, SJ; Harris, M; O'Brien, WF; Stromquist, C, 1991) |
| "Indomethacin was given for the treatment of preterm labor in a twin pregnancy at a dosage of 200 mg/day for 7 days beginning at 34 weeks and 5 days' gestation." | 3.68 | Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation. ( Ayres, NA; Hallak, M; Moise, KJ; Reiter, AA, 1991) |
| "Female Sceloporous jarrovi in late pregnancy given an ip injection of progesterone (50 ng/g body wt) or indomethacin (4 micrograms/g body wt) exhibited no change in the length of pregnancy when compared to saline-treated controls." | 3.68 | Exogenous progesterone or indomethacin delays parturition in the viviparous lizard Sceloporus jarrovi. ( DeMarco, V; Guillette, LJ; Palmer, BD, 1991) |
| "Fifteen patients with polyhydramnios and clinical symptoms related to excess amniotic fluid volume were treated with indomethacin therapy that was started at a mean gestational age of 27." | 3.68 | Maternal indomethacin therapy in the treatment of polyhydramnios. ( Andreou, A; Assimakopoulos, E; Mamopoulos, M; Mantalenakis, S; Reece, EA; Zheng, XZ, 1990) |
| "Ten pregnancies with 13 fetuses complicated by symptomatic polyhydramnios were treated with indomethacin." | 3.68 | Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ; Wasserstrum, N, 1990) |
| "Continuous-wave Doppler ultrasound was used to assess blood flow velocities and determine the pulsatility index of the uterine arteries in ten pregnant women at 23-33 weeks' gestation during indomethacin therapy for preterm labor or polyhydramnios." | 3.68 | Uterine blood flow velocity waveforms in pregnant women during indomethacin therapy. ( Deter, RL; Kirshon, B; Mari, G; Moise, KJ; Wasserstrum, N, 1990) |
| "A case of polyhydramnios was effectively treated with amniotic fluid decompression and indomethacin." | 3.68 | Indomethacin treatment for polyhydramnios and subsequent infantile nephrogenic diabetes insipidus. ( Cotton, DB; Kirshon, B; Smith, LG, 1990) |
| "A case of recurrent acute polyhydramnios successfully treated with indomethacin is described." | 3.68 | [Recurrent acute polyhydramnios treated with indomethacin]. ( Faber, BL, 1990) |
| "A case of twin reversed arterial perfusion (TRAP) sequence (acardiac twin) complicated by hydramnios was managed by maternal administration of indomethacin." | 3.68 | TRAP sequence--successful outcome with indomethacin treatment. ( Ash, K; Gritter, H; Harman, CR, 1990) |
| "The purpose of this study was to determine whether indomethacin alters the maternal and fetal hemodynamic response to magnesium sulfate (MgSO4) infusion and hemorrhage in gravid ewes." | 3.68 | Does indomethacin alter the hemodynamic response to magnesium sulfate infusion and hemorrhage in gravid ewes? ( Chestnut, DH; DeBruyn, CS; Thompson, CS; Weiner, CP, 1990) |
| "To investigate the effects of indomethacin on the human fetal renal blood flow velocity waveform, 17 fetuses whose mothers were treated for preterm labor (N = 8) or polyhydramnios (N = 9) were studied." | 3.68 | Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios. ( Carpenter, RJ; Deter, RL; Kirshon, B; Mari, G; Moise, KJ, 1990) |
| "Eight gravidas with symptomatic polyhydramnios were managed with maternal indomethacin therapy." | 3.68 | Indomethacin therapy in the treatment of symptomatic polyhydramnios. ( Kirshon, B; Mari, G; Moise, KJ, 1990) |
| "Six twin pregnancies complicated by hydramnios and premature labor were prospectively studied to determine whether indomethacin reduces amniotic fluid." | 3.67 | Twin with hydramnios: treating premature labor at source. ( Ash, KM; Harman, CR; Lange, IR; Manning, FA; Menticoglou, S, 1989) |
| "The premature closure of the ductus arteriosus (pcDA) due to maternal tocolysis with indomethacin in the 34th week of gestation was diagnosed in a twin pregnancy." | 3.67 | [Prenatal diagnosis of premature closure of the ductus arteriosus with subsequent development of a non-immunologic hydrops fetalis]. ( Bollmann, R; Chaoui, R; Hoffmann, H; Wauer, R, 1989) |
| " Groups A and B1 received intravascular volume expander, electrolytes replacement, and indomethacin up to 300 mg/day." | 3.67 | Severe ovarian hyperstimulation syndrome: a reevaluated therapeutic approach. ( Borenstein, R; Elhalah, U; Lunenfeld, B; Schwartz, ZS, 1989) |
| "Indomethacin was administered to suppress premature uterine contractions in a twin pregnancy from the 27th until the 32nd week of pregnancy." | 3.67 | Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report. ( Abramovici, H; Atad, J; Lissak, A; Rofe, A, 1987) |
| " Inhibition of prostaglandin (PG) synthesis by indomethacin (Id) during early pregnancy in rabbits apparently disrupts the process of sex steroid production by the ovaries." | 3.67 | Effect of indomethacin on plasma levels of vitamin D metabolites, oestradiol and progesterone in rabbits during early pregnancy. ( el-Banna, AA; Sedrani, SH, 1987) |
| " We took advantage of the treatment of pregnant women with indomethacin, because of premature labor or hydramnios, to investigate the role of prostaglandins in the activation of T suppressor (TS) activity." | 3.67 | The effects of indomethacin administration during pregnancy on women's and newborns' T-suppressor lymphocyte activity and on HLA class II expression by newborns' leukocytes. ( Brami, C; Durandy, A; Griscelli, C, 1985) |
| "2 to 31 wk) exposed to indomethacin during the last 2 days of pregnancy (group I)." | 3.67 | Renal functional impairment in preterm neonates related to intrauterine indomethacin exposure. ( Grose, W; Nauta, J; Oranje, WA; Provoost, AP; Sauer, PJ; vd Heijden, AJ; Wolff, ED, 1988) |
| "The role of microsomal placental leucine aminopeptidase (microsomal P-LAP) in the decreased pressor responsiveness to angiotensin II (A-II) in pregnancy was studied." | 3.67 | Effect of microsomal leucine aminopeptidase from human placenta (microsomal P-LAP) on pressor response to infused angiotensin II (A-II) in rat. ( Furuhashi, M; Imaizumi, H; Ito, Y; Kurauchi, O; Mizutani, S; Narita, O; Taira, H; Tomoda, Y, 1987) |
| " In experiment 3, conceptuses were recovered on days 16, 20 and 24 of pregnancy and incubated with [3H] AA to determine the effects of indomethacin on [3H] AA metabolism." | 3.67 | Metabolism of arachidonic acid in vitro by ovine conceptuses recovered during early pregnancy. ( Lewis, GS; Waterman, RA, 1985) |
| "Indomethacin 10 mg/kg was administered to the maternal rat on the 21st day of pregnancy, and the fetal and neonatal ductus arteriosus were studied using the rapid whole-body freezing technique." | 3.67 | Characteristic morphology of the constricted fetal ductus arteriosus following maternal administration of indomethacin. ( Hagiwara, H; Konishi, T; Momma, K, 1985) |
| " with indomethacin (10 mg/kg) twice daily on days 5 and 6 and on the morning of day 7 of pregnancy or pseudopregnancy and killed 2 h after the last injection." | 3.67 | Progesterone and oestradiol receptor concentration and translocation in uterine tissue of rabbits treated with indomethacin. ( Cao, ZD; Harper, MJ; Jones, MA, 1985) |
| "Indomethacin (IM), a potent inhibitor of prostaglandin synthetase, significantly inhibited implantation in rats when administered at a single subcutaneous dose of 15 mg/kg on day 2 or 3 of pregnancy or at a dose of 800 micrograms administered intraluminally in the uterus on day 4 of pregnancy." | 3.66 | Evidence for a possible role of prostaglandins in implantation in rats. ( Chaudhury, RR; Garg, SK, 1983) |
| "Arachidonic acid produces a significant reversal of the production of cleft palate by cortisone in the offspring of sensitive strains of mice in vivo." | 3.66 | Further evidence for a role of arachidonic acid in glucocorticoid teratogenic action in the palate. ( Goldman, AS; Herold, R; Piddington, R, 1983) |
| "A pregnancy during which both beta-adrenergics and indomethacin were administered in order to stop preterm uterine contractions is reported." | 3.66 | Indomethacin and the fetal renal nonfunction syndrome. ( de Jong, PA; van Wijck, JA; Veersema, D, 1983) |
| "Three antiprostaglandin drugs, acetylsalicylic acid, indomethacin and ibuprofen, were administered intraluminally at different does to pregnant rats on Day 4 of pregnancy." | 3.66 | Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat. ( Chaudhury, RR; Gupta, U; Malhotra, N; Varma, SK, 1981) |
| "To determine the effective time of indomethacin (Id) action in disrupting early pregnancy, groups of rabbits were treated at various stages after mating with Id and/or replacement doses of PGF2 alpha." | 3.66 | The degenerative effect on rabbit implantation sites by indomethacin. I. Timing of indomethacin action, possible effect on uterine proteins and the effect of replacement doses of PGF2 alpha. ( El-Banna, AA, 1980) |
| " The effects of acetaminophen in pregnancy and in the newborn have not been studied extensively; when ingested in usual therapeutic doses, the available data have shown no adverse effects." | 3.66 | Effects of aspirin and acetaminophen in pregnancy and in the newborn. ( Rudolph, AM, 1981) |
| "Two twins born to a mother who had been treated with Indomethacin at the end of pregnancy presented with variable but transitory hypoxemia." | 3.66 | [Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)]. ( Boulley, AM; Dehan, M; Gabilan, JC; Hernandorena, X; Laudignon, N; Lhermitte, C; Ropert, JC; Vial, M, 1980) |
| "In gravid women who are destined to develop pregnancy-induced hypertension (PIH), normal pregnancy-associated refractoriness to the pressor effects of administered angiotensin II (A-II) is lost several weeks before the onset of hypertension." | 3.66 | Modification of vascular responsiveness to angiotensin II in pregnant women by intravenously infused 5alpha-dihydroprogesterone. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "Pregnant women destined to develop pregnancy-induced hypertension (PIH) lose refractoriness to the pressor effects of infused angiotensin II (A-II) several weeks before the onset of hypertension." | 3.66 | Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1978) |
| "Since the effects of prostaglandin synthetase inhibitors on the developing human fetal pulmonary vasculature are unknown, we studied the lungs of two infants, one whose mother took salicylates and the other whose mother took indomethacin during pregnancy." | 3.66 | Morphologic analysis of the pulmonary vascular bed in infants exposed in utero to prostaglandin synthetase inhibitors. ( Fixler, DE; Levin, DL; Morriss, FC; Tyson, J, 1978) |
| "The effect of indomethacin as an antagonist to prostaglandin was evaluated on a series of 16 women during spontaneous labour in the ninth month of pregnancy." | 3.65 | The effect of indomethacin in labour at term. ( Atad, J; Reiss, U; Rubinstein, I; Zuckerman, H, 1976) |
| "Indomethacin administration in late pregnancy prolonged gestation in caged rhesus monkeys and inhibited premature labour and postponed delivery in chronically catheterized monkey fetuses." | 3.65 | Endocrine and pharmacological factors which influence the onset of labour in rhesus monkeys. ( Novy, MJ, 1977) |
| " During treatment with the basic drugs: gold, D-penicillamine and chloroquine, pregnancy should be avoided." | 3.65 | [Problems of rheumatic therapy in pregnancy (author's transl)]. ( Bischof, P, 1976) |
| "The rise in arterial blood pressure in response to angiotensin II was studied in the last third of pregnancy in rabbits." | 3.65 | The effect of prostaglandin E2 on the cardiovascular response to angiotensin II in pregnant rabbits. ( Broughton Pipkin, F; Filshie, GM; O'Brien, PM, 1977) |
| "75 mg/day); phenylbutazone (20 mg/day); flufenamic acid (10 mg/day); and Compound 83161 (tetrazolo less than 1,5-alpha greater than s-triazolo less than 3,4-c greater than quinoxoline) (8 mg/day and 12 mg/day) were each given to intact rats during early pregnancy (days 1 and/or 2 through day 8)." | 3.65 | Studies on the effects of pharmacologic doses of cortisone acetate and several nonsteroidal anti-inflammatory compounds on ovo-implantation, early pregnancy, and the deciduomal response in the rat. ( Bennett, DR; Cochrane, RL; Powell, JG; Rathmacher, RP; Shaar, CJ; Smalstig, EB, 1977) |
| "In the hamster administration of indomethacin twice a day on days 14 to 16 of pregnancy delayed the onset of parturition; a delay of 5 and 8 hours was observed following treatments of 300 or 600 mug/injection of indomethacin, respectively." | 3.65 | Effects of indomethacin and prostaglandin F2alpha on parturition in the hamster. ( Chang, MC; Lau, IF; Saksena, SK, 1975) |
| "The concentrations of free and protein-bound L-tryptophan were measured in sera from normal subjects, patients with rheumatoid arthritis, pregnant women, and patients with jaundice." | 3.65 | Mode of action of antirheumatic drugs. ( Dawkins, PD; Hamilton, EB; McArthur, JN; Smith, MJ, 1971) |
| "Preterm birth is the most common cause of neonatal morbidity and mortality." | 3.01 | The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol. ( Abdelrahiem, SK; Adam, I; Elfaki, T; Elhassan, EM; Ibrahim, MH, 2021) |
| "Diclofenac sodium was a more effective analgesic than indomethacin suppositories for right mediolateral episiotomy pain." | 2.77 | Comparison of diclofenac sodium with indomethacin suppositories for mediolateral episiotomies. ( Altungül, AC; Kale, A; Sapmaz, E, 2012) |
| "Women in acute preterm labor with cervical dilatation 1-6 cm were randomized to receive one of three first-line tocolytic drugs." | 2.77 | Effect of antenatal tocolysis on neonatal outcomes. ( Briery, CM; Keiser, SD; Klauser, CK; Kosek, MA; Martin, RW; Morrison, JC, 2012) |
| "Indomethacin was less effective than nifedipine for the fast treatment of preterm labor." | 2.76 | Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor. ( Bahasadri, S; Kashanian, M; Zolali, B, 2011) |
| "Termination of pregnancy is a painful procedure." | 2.72 | Efficacy of suppository analgesia in postabortion pain reduction. ( Deutsch, M; Glik, A; Granot, M; Jakobi, P; Lowenstein, L; Tamir, A; Zimmer, EZ, 2006) |
| " Observations collected in two population pharmacokinetic studies, in preterm neonates, investigating amikacin and vancomycin were used to estimate: i) the impact of ibuprofen administration on the clearance of these drugs; and ii) the difference between prophylactic and therapeutic administration of ibuprofen on this clearance." | 2.72 | Impact of ibuprofen administration on renal drug clearance in the first weeks of life. ( Allegaert, K; Anderson, BJ; Rayyan, M, 2006) |
| " There were no significant maternal or neonatal adverse events." | 2.70 | A prospective randomized safety trial of celecoxib for treatment of preterm labor. ( Bernhard, LM; Gerber, S; Gross, GA; Leguizamon, G; Levy, R; Mathur, A; Nelson, DM; Sadovsky, Y; Stika, CS, 2002) |
| "Indomethacin was administered as 50-mg rectal suppositories." | 2.70 | A retrospective study of the effect of postoperative indomethacin rectal suppositories on the need for narcotic analgesia in patients who had a cesarean delivery while they were under regional anesthesia. ( Ambrose, FP, 2001) |
| "Tocolysis in advanced preterm labor delays delivery by more than 48 hours in 50% of patients." | 2.68 | Tocolysis in advanced preterm labor: impact on neonatal outcome. ( Barke, JI; de Veciana, M; Major, CA; Porto, M, 1995) |
| "Indomethacin has a significant reversible constrictive effect on the fetal ductus arteriosus that is associated with secondary changes, especially in the right ventricle." | 2.68 | Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor: a randomized study. ( Jouppila, P; Räsänen, J, 1995) |
| "Cerebral palsy was found in 36 (9." | 2.68 | Antecedents of cerebral palsy in a multicenter trial of indomethacin for intraventricular hemorrhage. ( Allan, WC; Katz, KH; Makuch, RW; Ment, LR; Vohr, B, 1997) |
| "Magnesium sulfate was administered intravenously with an 8 gm loading dose given over the first hour, 4 gm over the second hour, and then a maintenance infusion of 2." | 2.68 | Lack of effect of antenatal indomethacin on fetal cerebral blood flow. ( Clark, E; Cohen, LS; Parilla, BV; Tamura, RK, 1997) |
| "If recurrent preterm labor occurred despite maximization of therapy, the treatment arm was determined and therapy was changed; saline pump and oral terbutaline were switched to terbutaline pump, terbutaline pump was switched to oral terbutaline." | 2.68 | A placebo-controlled randomized trial of the terbutaline pump for prevention of preterm delivery. ( Merrill, D; Niebyl, J; Weiner, CP; Wenstrom, KD, 1997) |
| "Eighty pregnant women threatened with preterm labor between 24 and 34 weeks of gestation were enrolled in the study." | 2.67 | Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor. ( Eronen, M; Hallman, M; Kurki, T; Pesonen, E; Teramo, K; Ylikorkala, O, 1994) |
| "Indomethacin was as effective as magnesium sulfate in delaying delivery > 48 hours, 90% versus 85%, and together with oral terbutaline in extending the gestation, 22." | 2.67 | Efficacy and safety of indomethacin compared with magnesium sulfate in the management of preterm labor: a randomized study. ( Madhav, H; Morales, WJ, 1993) |
| "Thirty-six women in preterm labor who had failed initial attempts at tocolysis with magnesium sulfate were randomized to receive either oral indomethacin or oral sulindac for 48 hours." | 2.67 | Randomized comparative trial of indomethacin and sulindac for the treatment of refractory preterm labor. ( Carlan, SJ; Mastrogiannis, D; O'Brien, WF; O'Leary, TD, 1992) |
| "Nylidrin treatment was accompanied by a 35% rise in COMT activity 3 h later, whereas indomethacin caused no significant change." | 2.67 | Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin. ( Kurki, T; Lindén, IB; Schultz, E; Ylikorkala, O, 1991) |
| "Indomethacin treatment was accompanied by maternal side effects 20% of the time, significantly less commonly (P less than ." | 2.67 | A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor. ( Eronen, M; Kurki, T; Lumme, R; Ylikorkala, O, 1991) |
| "Forty patients with intact membranes in preterm labor at 23 to 34 weeks' gestation were randomized to receive either intravenous ritodrine or oral indomethacin as the first-line tocolytic agent." | 2.67 | Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor. ( Besinger, RE; Johnson, TR; Keyes, WG; Niebyl, JR, 1991) |
| " In an attempt to prevent PTB in singleton pregnancies, cervical cerclage, in combination with other treatments, has been advocated." | 2.66 | Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies. ( Eke, AC; Eleje, GU; Ezebialu, IU; Ikechebelu, JI; Ilika, CP; Okam, PC, 2020) |
| " Tocolysis with indomethacin was associated with no maternal side effects, whereas tocolysis with ritodrine hydrochloride was associated with a 24% incidence of serious cardiovascular and metabolic adverse effects prompting discontinuation of the drug." | 2.66 | Efficacy and safety of indomethacin versus ritodrine in the management of preterm labor: a randomized study. ( Angel, JL; Knuppel, RA; Morales, WJ; O'Brien, WF; Smith, SG, 1989) |
| " 200-300 mg of indomethacin was the total dosage in a 24 hours period." | 2.65 | Further study of the inhibition of premature labor by indomethacin. Part II double-blind study. ( Gilad, G; Katzuni, E; Shalev, E; Zuckerman, H, 1984) |
| "One hundred cases of threatened abortion were randomly allocated to four lines of treatment namely, long acting progesterone, antispasmodic, indomethacin and placebo." | 2.65 | Therapeutic value of indomethacin in threatened abortion. ( Einen, MA; Osman, M; Sibaie, F; Souka, AR, 1980) |
| "Indomethacin was significantly more effective than placebo in inhibition of premature labor during a 24-hour course of therapy, with treatment failure during therapy occurring in only one of 15 indomethacin-treated patients compared to nine of 15 placebo-treated patients (p less than 0." | 2.65 | The inhibition of premature labor with indomethacin. ( Blake, DA; Dubin, NH; Egner, PG; Kumor, KM; Niebyl, JR; Robinson, JC; White, RD, 1980) |
| "Indomethacin pretreatment shortened the duration of PGE2-induced abortion in primigravid and multigravid groups of patients by about 4 and 2 hours respectively." | 2.65 | Indomethacin increases abortifacient effect of PGE2 in man. ( Basta, A; Dłuzniewska, M; Klimczyk, K; Małolepazy, A; Piotrowski, J; Spławinski, JA, 1979) |
| " The first treatment consisted of the administration of ritodrine and a placebo; in the second, ritodrine was combined with indomethacin." | 2.64 | A study of indomethacin combined with ritodrine in threatened preterm labor. ( Cañas, E; Cararach, V; Edo, A; Gamissans, O; Puerto, B; Ribas, J, 1978) |
| " On the other hand, several adverse effects have been reported with such medications, including peripheral vasoconstriction, gastrointestinal bleeding and perforation, weakened platelet aggregation, hyperbilirubinemia and renal failure." | 2.52 | Safety of therapeutics used in management of patent ductus arteriosus in preterm infants. ( Erdeve, O; Oncel, MY, 2015) |
| "Preterm birth is a major cause of perinatal mortality and morbidity." | 2.52 | Cyclo-oxygenase (COX) inhibitors for treating preterm labour. ( Dos Santos, RA; Flenady, V; Kumar, S; Pileggi-Castro, C; Reinebrant, HE; Romero, CL; Souza, JP, 2015) |
| "The treatment with ibuprofen reduces the urine output and increases the serum creatinine concentrations less extensively than indomethacin." | 2.50 | Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus. ( Pacifici, GM, 2014) |
| "The pathophysiology leading to preterm labor is not well understood and often multifactorial; initiating factors include intrauterine infection, inflammation, ischemia, overdistension, and hemorrhage." | 2.48 | Tocolytic therapy for acute preterm labor. ( Abramovici, A; Cantu, J; Jenkins, SM, 2012) |
| "Although ongoing patency of the ductus arteriosus is common in small extremely preterm infants, consensus is lacking regarding its clinical significance and treatment strategies." | 2.48 | The ductus arteriosus: a refined approach! ( McNamara, PJ; Sehgal, A, 2012) |
| "Although a moderate-sized patent ductus arteriosus (PDA) needs to be closed by the time a child is 1-2 years old, there is great uncertainty about whether it needs to be closed during the neonatal period." | 2.48 | Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all? ( Clyman, RI; Couto, J; Murphy, GM, 2012) |
| "NSAIDs are generally considered to be safe and well tolerated, but, even with the advent of selective COX-2 inhibitors, nephrotoxicity remains a concern." | 2.47 | Acute nephrotoxicity of NSAID from the foetus to the adult. ( Antonucci, R; Evangelista, M; Fanos, V; Finco, G; Musu, M; Polati, E; Ribuffo, D; Sanna, D; Schweiger, V, 2011) |
| "Ibuprofen lysine has demonstrated significantly less effects on cerebral, renal, and mesenteric blood flow in premature neonates when compared with indomethacin." | 2.44 | Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus. ( Pai, VB; Puthoff, TD; Sakadjian, A, 2008) |
| "Although our pooled results did not identify significantly increased risks of adverse effects, the limited statistical power of published randomized trials does not allow us to exclude the possibility that indomethacin tocolysis increases the risk of adverse neonatal outcomes." | 2.43 | Assessing the neonatal safety of indomethacin tocolysis: a systematic review with meta-analysis. ( Kaunitz, AM; Loe, SM; Sanchez-Ramos, L, 2005) |
| "Indomethacin is a prostaglandin synthetase inhibitor sometimes used for tocolysis." | 2.41 | The controversy surrounding indomethacin for tocolysis. ( Clothier, B; Macones, GA; Marder, SJ; Stamilio, DM, 2001) |
| "Twin to twin transfusion syndrome and twin reversed arterial perfusion sequence affect up to 15% of monozygotic twin pregnancies." | 2.39 | Fetal therapy. ( Nicolaides, K; Pettersen, H, 1994) |
| "Indomethacin has been shown to reduce amniotic fluid volume in certain cases, but a strict monitoring schedule should be followed whenever it is administered." | 2.39 | Treatment of polyhydramnios with indomethacin. ( Kirshon, B; Kramer, WB; Van den Veyver, IB, 1994) |
| "In all six cases, severe hydramnios occurred during pregnancy between the 26th and 28th week after the last menstrual period." | 2.38 | [Antenatal form of Bartter's syndrome]. ( Broyer, M; Burguet, A; Dechaux, M; Deschenes, G; Garabedian, M; Guyot, C; Hubert, P; Loirat, C, 1993) |
| "Polyhydramnios is an uncommon cause of premature labor and delivery." | 2.38 | Polyhydramnios: does reducing the amniotic fluid volume decrease the incidence of prematurity? ( Rodriguez, MH, 1992) |
| "When Indomethacin in a dosage of 175 mg/day was used to treat threatened premature labour more than 70% of cases carried on until 37 weeks." | 2.37 | [Value and dangers of indomethacin used in pregnancy. Apropos of 304 treated patients]. ( Barrat, J; Bouillie, J; Boyer, F; Keskes, J; Marpeau, L; Pigné, A; Vincenti, O, 1988) |
| "Normal human pregnancy is characterized by vascular refractoriness to AII." | 2.36 | Control of vascular responsiveness during human pregnancy. ( Everett, RB; Gant, NF; MacDonald, PC; Worley, RJ, 1980) |
| "Naproxen is an acidic drug that is highly bound to plasma albumin." | 2.36 | Naproxen sodium (Anaprox): pharmacology, pharmacokinetics and drug interactions. ( Segre, EJ, 1980) |
| "Effective inhibition of premature labor depends on prompt initiation of treatment." | 2.36 | Drugs for inhibition of premature labor. ( Niebyl, JR, 1979) |
| "Prenatally diagnosed Ebstein's anomaly with tricuspid valve dysplasia (EA/TVD) is a rare and high-risk congenital heart malformation with limited effective treatments." | 1.72 | Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy. ( Kraus, E; Lannaman, K; Powel, JE; Reddy, C, 2022) |
| "Indomethacin has been proven to be more effective than other tocolytic agents in terms of delaying birth but is often prescribed with caution because of its potential association with adverse neonatal outcomes." | 1.62 | The relationship between antenatal indomethacin as a tocolytic drug and neonatal outcomes: a retrospective cohort study. ( Dieleman, JP; Janssen, LCE; Lingius, S; Niemarkt, HJ; Rovers, JFJ; Thomissen, IJC; van Runnard Heimel, PJ; Wieland, BV, 2021) |
| " Initial dosing consisted of indomethacin, followed by ibuprofen in most cases." | 1.62 | Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly). ( Beroukhim, RS; Cumbermack, KM; Ferrer, Q; Freud, LR; Glickstein, JS; LaFranchi, T; Makhoul, M; Morris, SA; Pedra, SR; Phoon, CK; Sun, HY; Tworetzky, W; Wilkins-Haug, LE, 2021) |
| "Indomethacin treatment for patent ductus arteriosus (PDA) is associated with acute kidney injury (AKI)." | 1.56 | Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness. ( Berger, CD; Boatwright, N; Crockett, SL; Harris, M; Reese, J; Segar, JL; Shelton, EL; Su, RL; Yarboro, MT, 2020) |
| " The association of DA constriction and low BMI suggests that BMI-based dosing of indomethacin may be recommended for perioperative tocolysis in fetal MMC surgery." | 1.56 | Maternal low body mass index is a risk factor for fetal ductal constriction following indomethacin use among women undergoing fetal repair of spina bifida. ( Belfort, MA; Cortes, MS; Donado, MY; Erfani, H; Espinoza, J; Furtun, BY; Nassr, AA; Olutoye, O; Shamshirsaz, AA; Velez, MP; Whitehead, WE, 2020) |
| " We sought to determine whether a relationship exists between preoperative indomethacin dosing and fetal DA constriction." | 1.51 | Indomethacin Dosing and Constriction of the Ductus Arteriosus During Open Fetal Surgery for Myelomeningocele Repair. ( Behrendt, N; Chatterjee, D; Crombleholme, TM; Cuneo, BF; Galan, HL; Howley, LW; Marwan, AI; Patel, SS; Wood, C; Zaretsky, MV; Zuk, J, 2019) |
| " The concentration of ETV in the liver was not obviously altered during pregnancy, which indicates that dosage adjustment in pregnancy is not necessary." | 1.51 | Roles of organic anion transporter 2 and equilibrative nucleoside transporter 1 in hepatic disposition and antiviral activity of entecavir during non-pregnancy and pregnancy. ( Bai, M; Jiang, H; Jiang, T; Lin, N; Lu, S; Ma, Z; Sun, D; Zeng, S; Zhou, H, 2019) |
| "Infection of a maternal urachal cyst during pregnancy is rare; Sonography is an important diagnostic tool that can help minimize maternal and fetal complications." | 1.48 | Sonographic detection of an infected maternal urachal cyst during pregnancy. ( Sargent, J; Sohaey, R; Trivedi, N, 2018) |
| "Indomethacin has been administered for longer durations to prolong gestation in extreme prematurity." | 1.43 | Perinatal Outcomes after Short versus Prolonged Indomethacin for Tocolysis in Women with Preterm Labor. ( Behnia, F; Costantine, M; Dutta, EH; Harirah, H; Saade, G, 2016) |
| "Indomethacin (IND) is a prostaglandin production inhibitor that reduces uterine contractions, but crosses the placenta leading to adverse fetal effects." | 1.42 | Liposomes: a nanoscale drug carrying system to prevent indomethacin passage to the fetus in a pregnant mouse model. ( Alexander, JF; Godin, B; Leon, M; Leonard, F; Longo, M; Refuerzo, JS, 2015) |
| "The management of a patent ductus arteriosus in preterm infants continues to be debated among neonatologists due to the absence of concrete evidence that precisely weighs the long term outcomes of active, early intervention against a conservative approach." | 1.42 | A prospective study of maternal preference for indomethacin prophylaxis versus symptomatic treatment of a patent ductus arteriosus in preterm infants. ( AlFaleh, K; AlKharfi, T; Alluwaimi, E; AlOsaimi, A; AlOtaibi, B; Alrajebah, S; AlRasheed, F; Paes, B, 2015) |
| " We found no dose-response effect." | 1.40 | Fetal exposure to nonsteroidal anti-inflammatory drugs and spontaneous abortions. ( Bilenko, N; Daniel, S; Koren, G; Levy, A; Lunenfeld, E; Ratzon, R, 2014) |
| "Antenatal Bartter syndrome is characterized by severe polyhydramnios in mother leading to premature delivery." | 1.40 | Antenatal Bartter syndrome. ( Afzal, M; Anwar, V; Azam, S; Khan, EA; Khan, WA; Rafiq, S; Yaqoob, A, 2014) |
| "Indomethacin has vasoactive properties in cerebral and systemic vascular beds, and it improves cerebral autoregulatory ability." | 1.39 | Tocolytic indomethacin: effects on neonatal haemodynamics and cerebral autoregulation in the preterm newborn. ( Baerts, W; Derks, JB; Lemmers, PM; Thewissen, L; van Bel, F, 2013) |
| "Indomethacin has been also used in women with short cervices as well as in those with idiopathic polyhydramnios." | 1.38 | Indomethacin in pregnancy: applications and safety. ( Abou-Ghannam, G; Nassar, AH; Usta, IM, 2012) |
| "The effect of patent ductus arteriosus (PDA) treatment with cyclooxygenase (COX) inhibitors (indomethacin [INDO] and ibuprofen [IBU]) on regional oxygenation requires further clarification." | 1.38 | Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation? ( Bhatt, M; Mehta, R; Petrova, A, 2012) |
| "Indomethacin alone was without effect on MT in MA from either nonpregnant or pregnant women." | 1.38 | Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms. ( Charles, SM; Eckman, DM; Gupta, R; Mertz, H; Moore, LG; Morgan, TM; Rosenfeld, CR, 2012) |
| "Pregnancy in patients with chronic renal failure occurs rarely but the incidence is increasing." | 1.37 | Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report. ( Baykal, C; Kaya, S; Takal, MK; Yakupoğlu, U, 2011) |
| "Furosemide was also s." | 1.36 | In vivo dilatation of the ductus arteriosus induced by furosemide in the rat. ( Momma, K; Nakanishi, T; Toyoshima, K, 2010) |
| "Necropsy revealed patent ductus arteriosus with normal intimal thickening but dilated cardiac chambers." | 1.36 | Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice. ( Chang, HY; Locker, J; Lu, R; Schuster, VL, 2010) |
| "The treatment with Indomethacin in the antenatal period can prevent severe nephrocalcinosis." | 1.36 | Antenatal Bartter syndrome: analysis of two cases with placental findings. ( Aksoy, F; Cetin, A; Dane, B; Dane, C; Yayla, M, 2010) |
| "Anandamide (AEA) has been reported to have pleiotropic effects on reproduction, but the mechanism by which it exerts these effects is unclear." | 1.35 | Dual effect of anandamide on rat placenta nitric oxide synthesis. ( Cella, M; Cervini, M; Farina, MG; Franchi, AM; Guadagnoli, T; Leguizamón, GF; Ribeiro, ML; Sordelli, MS, 2008) |
| "Sevoflurane was a vasodilator in the feto-placental vasculature in this in vitro model." | 1.35 | Sevoflurane and the feto-placental vasculature: the role of nitric oxide and vasoactive eicosanoids. ( Burke, P; Crowe, S; Farragher, R; Flynn, NM; Higgins, BD; Laffey, CD; Laffey, JG; Maharaj, CH, 2008) |
| "Glyburide, a drug used to treat gestational diabetes has previously been shown not to be measurable in fetal blood, and to be transferred from the fetal to the maternal circulation against a concentration gradient." | 1.35 | Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta. ( Anger, G; Gedeon, C; Koren, G; Lubetsky, A; Miller, MP, 2008) |
| "Indomethacin is used to close the patent ductus arteriosus in premature infants and for tocolysis of preterm labor." | 1.35 | Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat. ( Imamura, S; Ito, K; Momma, K; Nakanishi, T; Sugiyama, K; Sun, F; Toyoshima, K, 2009) |
| "Indomethacin was administered on a daily basis to female Sprague-Dawley rats at doses of 0, 0." | 1.35 | Collaborative work on evaluation of ovarian toxicity. 12) Effects of 2- or 4-week repeated dose studies and fertility study of indomethacin in female rats. ( Fujiwara, M; Ito, S; Kushima, K; Matsumoto, M; Matsuo, S; Nakatsuji, S; Oishi, Y; Saegusa, T; Seki, J; Tsubota, K; Yamauchi, K, 2009) |
| "Polyhydramnios was detected and the chloride level of the amniotic fluid was high." | 1.35 | Indomethacin-induced colon perforation in Bartter's syndrome. ( Ataoglu, E; Civilibal, M; Murat, E; Oktay, ER; Ozkul, AA; Varal, IG, 2009) |
| "We hypothesized that in preeclampsia (PE), contribution of endothelium-derived hyperpolarizing factor (EDHF) and the mechanism/s of its action differ from that in normal pregnancy (NP)." | 1.35 | Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites. ( Hultenby, K; Kublickas, M; Kublickiene, K; Luksha, L; Luksha, N; Nisell, H, 2008) |
| "Indomethacin was given p." | 1.35 | Indomethacin promotes nitric oxide function in the ductus arteriosus in the mouse. ( Baragatti, B; Barogi, S; Coceani, F; Laubach, VE; Sodini, D, 2008) |
| "Indomethacin was used as a tocolytic at a median dose of 250 mg, for a duration of 2 days, and ending 1 day before delivery." | 1.34 | The effects of indomethacin tocolysis on the postnatal response of the ductus arteriosus to indomethacin in extremely low birth weight infants. ( Cordero, L; Gardner, D; Giannone, PJ; Nankervis, CA, 2007) |
| " Immunophenotyping analysis using flow cytometry (FCM) indicated that the proportion and number of CD45RA(+) cells increased, and the proportion of CD3(-) NKR-P1A(+) cells decreased in males when dosed with IND at 1." | 1.34 | Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats. ( Fujiwara, M; Furusawa, S; Kushima, K; Oda, K; Sakuma, S, 2007) |
| "Indomethacin is known to cause renal failure in up to 25% of infants treated." | 1.34 | Renal glomeruli and tubular injury following indomethacin, ibuprofen, and gentamicin exposure in a neonatal rat model. ( Dahlstrom, JE; Falk, MC; Kent, AL; Koina, ME; Maxwell, LE; Willenborg, D, 2007) |
| "Chorioamnionitis was positively correlated with the risk, but did not reach statistical significance." | 1.33 | Possible antenatal and perinatal related factors in development of cystic periventricular leukomalacia. ( Itakura, A; Matsuzawa, K; Mizutani, S; Murata, Y; Okumura, A; Wakai, K, 2005) |
| "The indomethacin-induced increase in pressure was reduced in diabetes (2." | 1.33 | Dysfunction of the cyclo-oxygenase pathway in the foetoplacental circulation in Type 1 diabetes mellitus. ( Bisseling, TM; Elving, L; Russel, FG; Smits, P; Steegers, EA; Wouterse, AC, 2005) |
| "The oxytocin responses were similar at all lengths." | 1.33 | Shortening increases spontaneous contractility in myometrium from pregnant women at term. ( Gibbs, SG; Guy, SR; Horowitz, GM; Hurd, WW; Ventolini, G, 2005) |
| "Aggressive tocolytic therapy for preterm labor with advanced cervical dilatation is efficacious, allows for steroid therapy, and allows delivery of more mature neonates." | 1.33 | Efficacy of aggressive tocolysis for preterm labor with advanced cervical dilatation. ( Goldkrand, J; Psomiadis, N, 2005) |
| "Indomethacin was not related to increased risk for periventricular-intraventricular hemorrhage or periventricular hemorrhagic infarction." | 1.33 | Indomethacin tocolysis and white matter injury in preterm infants. ( Flidel-Rimon, O; Friedman, S; Shinwell, ES; Steinberg, M, 2005) |
| "Treatment with indomethacin, which prevents the formation of PGF2alpha, caused the PBR density in the uterus of pseudopregnant rats at day 53 PP to be twice as high as in pseudopregnant control rats." | 1.33 | The effects of prostaglandin F2alpha treatment on peripheral-type benzodiazepine receptors in the ovary and uterus during pseudopregnancy of rats. ( Bar-Ami, S; Bendel, N; Gavish, M; Leschiner, S; Levin, E; Veenman, L, 2006) |
| " Dose-response curves were made with gradually increasing doses of Phe using an isolated kidney preparation in the presence of a NO synthase (NOS) inhibitor (L-NAME, 1 microM), a PG-synthesis inhibitor (indomethacin, 1 microM), both, or neither." | 1.32 | Pregnancy influence on the vascular interactions between nitric oxide and other endothelium-derived mediators in rat kidney. ( Anguiano, L; Bobadilla, RA; López Sanchez, P; Pérez-Alvarez, V, 2003) |
| "Antenatal Bartter Syndrome (ABS) is a rare autosomic recessive tubulopathy characterized by idiopathic hydramnios, fetal polyuria and elevated levels of amniotic chloride." | 1.32 | [Prenatal Bartter's syndrome. Report of two cases]. ( Billiemaz, K; Collet, F; Lavocat, MP; Prieur, F; Seffert, P; Tourne, G; Varlet, MN, 2003) |
| "Indomethacin treatment abolished these effects." | 1.32 | Prostanoids contribute to the oxygen-dependent regulation of vascular tone of human umbilical vein. ( Mildenberger, E; Siegel, G; Versmold, HT, 2004) |
| " BQ123 (1 microm) caused a rightward shift in the ET-1 dose-response curve, while indomethacin at a threshold concentration (28 nm) tended to have an opposite effect." | 1.32 | Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin. ( Adeagbo, AS; Coceani, F; Kelsey, L, 2004) |
| "Pretreatment with isradipine (10(-6) M) or indomethacin (10(-7) M), concentrations that themselves had no effect on spontaneous contractility, significantly increased the inhibitor responses to sevoflurane on amplitude and frequency of myometrial contractions, beginning at 1 MAC (P<0." | 1.32 | Interactive effect of sevoflurane with isradipine or indomethacin on spontaneous contractile activity of isolated pregnant rat myometrium. ( Bagcivan, I; Gursoy, S; Kafali, H; Karadas, B; Kaya, T; Kunt, N, 2004) |
| "Rofecoxib has a potent tocolytic effect in vitro." | 1.31 | In vitro study of tocolytic effect of rofecoxib, a specific cyclo-oxygenase 2 inhibitor. Comparison and combination with other tocolytic agents. ( Benchaib, M; Doret, M; Gharib, C; Mellier, G; Pasquier, JC; Piacenza, JM, 2002) |
| "Pregnancy is associated with a significant increase in uterine blood flow which contributes to optimal fetal development." | 1.31 | Pregnancy is associated with altered response to neuropeptide Y in uterine artery. ( Grbovic, L; Jovanovic, A; Jovanovic, S, 2000) |
| "Late pregnancy is characterized by a significantly diminished systolic blood pressure in conscious rats (-17 mmHg, P < 0." | 1.31 | Endothelium and aortic contraction to endothelin-1 in the pregnant rat. ( Dièye, AM; Gairard, A, 2000) |
| "Pretreatment with mannitol significantly suppressed the vasospastic effect of LPC." | 1.31 | Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery. ( Fukaya, T; Okatani, Y; Taniguchi, K; Wakatsuki, A; Watanabe, K, 2000) |
| "Indomethacin was more effective than NS-398, except for their actions on PGF(2 alpha)production by the day 29 placenta where indomethacin and NS-398 were equiactive." | 1.31 | Effects of indomethacin, NS-398 (a selective prostaglandin H synthase-2 inhibitor) and protein synthesis inhibitors on prostaglandin production by the guinea-pig placenta. ( Aitken, H; Poyser, NL, 2001) |
| "Indomethacin was capable of significantly reducing the basal perfusion pressure (P=0." | 1.31 | Indomethacin activity in the fetal vasculature of normal and meconium exposed human placentae. ( Bashiri, A; Holcberg, G; Huleihel, M; Katz, M; Malek, A; Mazor, M; Sapir, O; Schneider, H; Tsadkin, M, 2001) |
| "Nimesulide therapy was continued for eight days (5-16) and was associated with a prolongation of pregnancy of 27 days (6-69)." | 1.31 | Can a cyclo-oxygenase type-2 selective tocolytic agent avoid the fetal side effects of indomethacin? ( Bellini, P; Ghidini, A; Locatelli, A; Strobelt, N; Vergani, P, 2001) |
| "Tissues from women with preeclampsia demonstrated the highest contractile response to U46619." | 1.31 | Inhibition of cyclooxygenase but not nitric oxide synthase influences effects on the human omental artery of the thromboxane A2 mimetic U46619 and 17beta-estradiol. ( Belfort, MA; Garfield, RE; Saade, GR; Vedernikov, YP, 2001) |
| "Indomethacin-treated animals showed less nest building than controls between 1 and 5 h after injection (P<0." | 1.31 | Indomethacin blocks pre-partum nest building behaviour in the pig (Sus scrofa): effects on plasma prostaglandin F metabolite, oxytocin, cortisol and progesterone. ( Burne, TH; Gilbert, CL; Goode, JA; Murfitt, PJ; Walton, SL, 2002) |
| "Pregnancy is associated with a substantial increase in uterine artery blood flow, which may in part result from dilation in response to vascular endothelial growth factor (VEGF)." | 1.31 | Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake. ( Anthony, FW; Brawley, L; Hanson, MA; Itoh, S; Poston, L; Wheeler, T, 2002) |
| "When pregnancy is continued after death of one fetus in monochorionic twin pregnancy, the surviving fetus sometimes exhibits intrauterine death or brain damage." | 1.30 | Hysterotomy and selective delivery of an intrauterine dead fetus to prevent intrauterine death or brain damage of the surviving fetus in monochorionic twin pregnancy. ( Ito, T; Kadowaki, K; Makio, A; Nagata, N; Takahashi, H; Terakawa, N, 1997) |
| "The reasons for referral were hydrops (2), cardiomegaly (1), polyhydramnios and choroid plexus cyst (1), and polyhydramnios and teratoma of the neck (1)." | 1.30 | Isolated ductal closure in utero diagnosed by fetal echocardiography. ( Cavallé-Garrido, T; Farine, D; Heilbut, M; Leal, SD; Ryan, G; Smallhorn, JF, 1997) |
| "In women with preeclampsia, the function of the endothelium is compromised, and it is suggested that reduced nitric oxide synthesis may contribute to the elevation of blood pressure and activation of coagulation pathways." | 1.30 | Flow-mediated vasodilatation is enhanced in normal pregnancy but reduced in preeclampsia. ( Cockell, AP; Poston, L, 1997) |
| "Persistent patent ductus arteriosus was more common in those infants delivered within 48 hours of maternal indomethacin exposure (40% versus 20% (p<0." | 1.30 | Antenatal indomethacin--adverse fetal effects confirmed. ( Baxendale, H; Harding, J; McCowan, L; McLeay, E; O'Donnell, C; Souter, D, 1998) |
| "Since toxic epidermal necrolysis is a potentially fatal disease, awareness of a possible association is warranted." | 1.30 | Toxic epidermal necrolysis associated with treatment for preterm labor. ( Claessens, N; Delbeke, L; Lafaire, C; Lambert, J; Matthieu, L; Van Marck, E, 1998) |
| "Indomethacin tocolysis has been reported to increase the incidence of persistent PDA in premature infants." | 1.30 | Indomethacin tocolysis increases postnatal patent ductus arteriosus severity. ( Eidelman, AI; Ferber, B; Glaser, J; Hammerman, C; Kaplan, M; Schimmel, MS, 1998) |
| "A condition similar to preeclampsia was induced by infusing pregnant rats with the nitric oxide synthase inhibitor N G -nitro- L -arginine methyl ester through subcutaneously implanted osmotic minipumps." | 1.30 | The effect of indomethacin and prostacyclin agonists on blood pressure in a rat model of preeclampsia. ( Buhimschi, I; Chwalisz, K; Garfield, RE; Liao, QP; Saade, GR; Zlatnik, MG, 1999) |
| "Nitroglycerin infusion caused a significant increase in maternal and fetal heart rate and a significant decrease in maternal and fetal mean arterial pressure at a dosage of 10 microram/kg per minute, without a change in blood gas values." | 1.30 | Effects of nitroglycerin and indomethacin on fetal-maternal circulation and on fetal cerebral blood flow and metabolism in sheep. ( Harrison, MR; Heymann, MA; Morris, JA; Roman, C; Skarsgard, ED; VanderWall, KJ, 1999) |
| "The vessels from women with preeclampsia showed markedly reduced relaxation to bradykinin (p < 0." | 1.30 | Mechanisms of endothelium-dependent relaxation in myometrial resistance vessels and their alteration in preeclampsia. ( Ashworth, JR; Baker, PN; Johnson, IR; Warren, AY, 1999) |
| "We present a case of fetal hydrops associated with tricuspid regurgitation and ductal constriction developing within 30 hours of instituting indomethacin tocolysis in a 28-week singleton gestation." | 1.30 | Reversible fetal hydrops associated with indomethacin use. ( Digiosia, J; Martin, CB; Pratt, L; Swenson, JN; Trampe, B, 1997) |
| " The dose-response curves to angiotensin I (n = 6) were significantly displaced to the right by captopril in a concentration-dependent manner." | 1.29 | Effects of captopril on the human foetal placental circulation: an interaction with bradykinin and angiotensin I. ( de Moura, R; Lopes, MA, 1995) |
| "Trivial tricuspid valve regurgitation was detected at a mean of 26." | 1.29 | Fetal echocardiography during indomethacin treatment. ( Huhta, JC; Respondek, M; Weil, SR, 1995) |
| "Indomethacin was given intracerebroventricularly (i." | 1.29 | Prostaglandin E2 in cerebrospinal fluid of fetal and newborn sheep: central versus peripheral source. ( Adamson, SL; Bishai, I; Coceani, F; Engelberts, D; Jones, SA; Norton, JL, 1994) |
| "Indomethacin was discontinued beyond the 33rd week of gestational age." | 1.29 | [Has the use of indomethacin during pregnancy consequences in newborn infants? Prospective study of 83 pregnant women and 115 newborn infants]. ( Blot, P; Boissinot, C; Carbillon, L; de Gayffier, A; Germain, JF; Jacqz-Aigrain, E; Oury, JF; Sibony, O, 1994) |
| "In indomethacin-treated fetuses, in which the prostanoids had decreased and remained at approximately 20% normal, cooling initiated moderate nonshivering thermogenesis, and ventilation and cord occlusion caused no further changes." | 1.29 | Role of prostaglandin E2 and prostacyclin in nonshivering thermogenesis during simulated birth in utero. ( Power, GG; Takeuchi, M; Yoneyama, Y, 1994) |
| "Pretreatment with indomethacin significantly decreased the proportion of fetal death from 83% to < 25% in mice injected with 10 micrograms of LPS." | 1.29 | Bacterial lipopolysaccharide-mediated fetal death. Production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide. ( Branch, DW; Dudley, DJ; Edwin, SS; Mitchell, MD; Silver, RM; Simmons, DL; Trautman, MS, 1995) |
| "Oral indomethacin treatment for tocolysis has no impact on PT and aPTT; however, profound acute changes in maternal bleeding time occur." | 1.29 | The effect of indomethacin tocolysis on maternal coagulation status. ( Barth, WH; Hankins, GD; Lunt, CC; Satin, AJ, 1994) |
| "Isolated intestinal perforation has been described in premature neonates who were treated with indomethacin for patent ductus arteriosus." | 1.29 | Isolated small bowel perforation following intrauterine treatment with indomethacin. ( Bidiwala, KS; Delpino, ML; Fejgin, MD, 1994) |
| "Bradykinin relaxation was nearly completely or completely abolished in endothelium-denuded preparations and, in its place, there was often a small contraction." | 1.29 | Occurrence of endothelium-derived relaxing factor--nitric oxide in the lamb ductus arteriosus. ( Coceani, F; Kelsey, L; Seidlitz, E, 1994) |
| "No such convulsion has been described to date in pregnancy." | 1.29 | Indomethacin-induced maternal convulsion in the treatment of preterm labour. ( DeChazal, R; Halligan, A; Nan, A; Taylor, D, 1993) |
| "9 percent, P = 0." | 1.29 | Neonatal complications after the administration of indomethacin for preterm labor. ( Clyman, RI; Cooper, BA; Kuller, JA; Merrill, J; Norton, ME, 1993) |
| "Three cases of acute renal insufficiency in pregnant women who were treated with indomethacin for premature labor are reported." | 1.29 | Acute maternal renal insufficiency in premature labor treated with indomethacin. ( Boyd, EL; Nageotte, MP; Powers, DR; Steiger, RM; Towers, CV, 1993) |
| "Delayed birth intervals of triplets in preterm labor should be considered to improve perinatal salvage of immature triplets, although a successful outcome is rare and unexpected." | 1.29 | Delayed birth intervals of immature fraternal triplets in preterm labor. A case report. ( Daikoku, NH; Frattarrola, IG; Gopal, JJ; Graham, D; Rock, JA, 1993) |
| "Indomethacin was administered to fetal sheep during 8 hours at 124." | 1.29 | Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep. ( Harding, R; Thorburn, GD; Wlodek, ME, 1994) |
| "Pretreatment with indomethacin did not result in improved fetal survival." | 1.29 | A rabbit model for ascending infection in pregnancy: intervention with indomethacin and delayed ampicillin-sulbactam therapy. ( Gibbs, RS; Heddleston, L; McDuffie, RS, 1993) |
| "Another therapy involves the treatment for premature labor, which is the most common cause of pregnancy loss in dialysis patients." | 1.29 | Pregnancy in women with end-stage renal disease: treatment of anemia and premature labor. ( Ambrose, S; Hou, S; Hussey, M; Orlowski, J; Pahl, M; Wong, D, 1993) |
| "In the three cases of severe twin-to-twin transfusion syndrome no reduction of amniotic fluid in either sac was demonstrated." | 1.29 | Indomethacin in severe twin-to-twin transfusion syndrome. ( Cetrulo, CL; D'Alton, ME; Dilillo, L; Jones, JM; Sbarra, AJ, 1993) |
| "When indomethacin was given, arterial blood gases in both groups showed a mild increase in carbon dioxide tension and similar placental blood flows (about 30% of baseline) after bypass." | 1.29 | Exclusion of the placenta during fetal cardiac bypass augments systemic flow and provides important information about the mechanism of placental injury. ( Fenton, KN; Hanley, FL; Heinemann, MK, 1993) |
| " After pretreatment of myometrial explants with a cyclo-oxygenase inhibitor (indomethacin), the PGF2 alpha dose-response curve was shifted to the left and a maximal level of PGF2 alpha-induced IP accumulation was reached." | 1.29 | Prostaglandin F2 alpha stimulates inositol phosphate production in human pregnant myometrium. ( Breuiller-Fouche, M; Ferre, F; Geny, B; Maka, FD, 1993) |
| "Placental vessels of women with gestational diabetes were found to undergo a significantly larger contraction than normal vessels when exposed to posthypoxic reoxygenation or micromolar concentrations of hydrogen peroxide." | 1.29 | Gestational diabetes alters human placental vascular responses to changes in oxygen tension. ( Figueroa, R; Omar, HA; Tejani, N; Wolin, MS, 1993) |
| "Indomethacin was used for cyclooxygenase blockade and nordihydroguaiaretic acid was used to evaluate lipoxygenase inhibition." | 1.29 | Immunomodulation of cellular cytotoxicity to herpes simplex virus infection in pregnancy by inhibition of eicosanoid metabolism. ( Donovan, PK; Feinberg, BB; Gonik, B; Loftin, KC; Tan, NS, 1993) |
| "Indomethacin is a non steroidal anti-inflammatory agent widely employed in the treatment of premature contractions." | 1.29 | Good fetal outcome following prolonged indomethacin induced anhydramnios. Case report. ( Aboulafia, Y; Diamant, YZ; Lavie, O; Rabinowitz, R; Shen, O, 1995) |
| "Drug-induced immune system mediated agranulocytosis is a rare but potentially life-threatening condition." | 1.29 | Effective treatment of drug-induced agranulocytosis using recombinant human granulocyte colony stimulating factor in pregnancy. ( Fujiwaki, R; Furuya, H; Hata, K; Hata, T; Katoh, Y; Kitao, M, 1995) |
| "Pamidronate was the only agent tested which suppressed the increase in bone resorption associated with macrophage exposure to bone cement particles to levels which were not significantly different from unexposed calvaria." | 1.29 | Pharmacologic inhibition of particulate-induced bone resorption. ( Algan, SA; Horowitz, SM; Purdon, MA, 1996) |
| "Indomethacin was given at a dose of 3 mg/kg/day." | 1.29 | Treatment of symptomatic polyhydramnios with indomethacin. ( Cabrol, D; Jannet, D; Pannier, E, 1996) |
| "Histamine contractions were enhanced in endothelium-intact strips in the presence of 10 mumol/L L-NG-nitro arginine (competitive inhibitor of nitric oxide synthase) but not in the presence of 10 mumol/L indomethacin (cyclooxygenase inhibitor)." | 1.29 | Comparison of nitric oxide and prostacyclin in endothelium-dependent vasorelaxation of human umbilical artery at midgestation. ( Garfield, RE; Izumi, H; Makino, Y; Mohtai, H; Shirakawa, K, 1996) |
| "Indomethacin treatment at 3 mg/kg/day from day 18 to day 20 of gestation significantly decreased the activity of 15-PGDH in neonatal lungs." | 1.29 | Inhibitory effect of indomethacin on neonatal lung catabolism of prostaglandin E2: possible mechanism of the re-opening of the ductus arteriosus after indomethacin therapy. ( Akahori, F; Arishima, K; Ikeda, Y; Masaoka, T; Takizawa, T; Togashi, H; Yamamoto, M, 1996) |
| "Treatment with indomethacin as well as removal of the endothelium was followed by contractions of umbilical arteries and a reduced formation of prostacyclin." | 1.28 | Any physiological role for prostacyclin in regulation of fetal vessel tone? ( Klockenbusch, W; Schrör, K; Strobach, H, 1992) |
| "Indomethacin is a potent tocolytic agent used in premature labor." | 1.28 | Oligohydramnios induced by maternal indomethacin therapy. ( Aydin, C; Ozcan, FS; Uslu, T, 1992) |
| "Among the difficulties encountered, premature labor and polyhydramnios are common." | 1.28 | Indomethacin therapy and chronic hemodialysis during pregnancy. A case report. ( Dolkart, LA; Eshwar, KP; Reimers, FT, 1992) |
| "When indomethacin was used to inhibit prostaglandin synthesis, placental vascular resistance did not increase, placental blood flow did not decrease, and fetal blood gases remained at normal prebypass levels during and after fetal cardiac bypass." | 1.28 | Prostaglandin synthesis inhibition prevents placental dysfunction after fetal cardiac bypass. ( Assad, RS; Hanley, FL; Sabik, JF, 1992) |
| "Indomethacin was used for tocolysis and to maintain mild oligohydraminios (amniotic fluid index 5-7 cm)." | 1.28 | Intraoperative amniocentesis and indomethacin treatment in the management of an immature pregnancy with completely dilated cervix. ( Evans, DJ; King, K; Kofinas, AD, 1992) |
| "Treatment with indomethacin (2." | 1.28 | Isolated pulmonary resistance vessels from fetal lambs. Contractile behavior and responses to indomethacin and endothelin-1. ( Coceani, F; Wang, Y, 1992) |
| "With bFGF, increased bone resorption was observed at 10(-9) M but not at 10(-8) M." | 1.28 | Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones. ( Raisz, LG; Simmons, HA, 1991) |
| "Thirty-three women in preterm labor between 25 and 34 weeks of gestation were studied before, during, and after treatment with indomethacin (n = 16) or nylidrin (n = 17)." | 1.28 | Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin. ( Kurki, T; Viinikka, L; Ylikorkala, O, 1992) |
| "Pretreatment with indomethacin prevented these effects of T3." | 1.28 | Evidence for direct non-genomic effects of triiodothyronine on bone rudiments in rats: stimulation of the inositol phosphate second messenger system. ( Lakatos, P; Stern, PH, 1991) |
| "Treatment with indomethacin did not affect the initial rapid twitch-like contraction, but inhibited the augmented spontaneous motility." | 1.28 | Contraction and prostaglandin biosynthesis by myometrium from non-pregnant and pregnant rabbits in response to adenosine 5'-triphosphate. ( Suzuki, Y, 1991) |
| "Pregnancy is normally associated with vasodilation that, in hypertensive animals such as the spontaneously hypertensive rat, causes a profound decrease in blood pressure." | 1.28 | Enhanced endothelium-derived relaxing factor activity in pregnant, spontaneously hypertensive rats. ( Ahokas, RA; Mercer, BM; Sibai, BM, 1991) |
| "Magnesium sulfate was about three times more potent in causing inhibition of potassium chloride-induced contractions in uterine arteries from pregnant patients than in those from nonpregnant patients." | 1.28 | Magnesium sulfate-induced relaxation of uterine arteries from pregnant and nonpregnant patients. ( Nelson, SH; Suresh, MS, 1991) |
| "Indomethacin was found not to be metabolized by the fetus." | 1.28 | A method to inject the umbilical vein of the rat. ( Nanbo, T, 1990) |
| "Provided that preeclampsia comprises enhanced vascular actions of thromboxane A2, the present results support the established use of Mg++ in the treatment of this condition and suggest that calcium antagonists are of potential benefit." | 1.28 | Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy. ( Andersson, KE; Forman, A; Skajaa, K; Svane, D, 1990) |
| "Indomethacin was given as part of tocolytic management to mothers with a high incidence of early rupture of membranes and preterm labour; and 76 fetuses were exposed to the drug as a result." | 1.28 | Cerebral lesions in preterm infants after tocolytic indomethacin. ( Baerts, W; Fetter, WP; Hop, WC; Sauer, PJ; Spritzer, R; Wallenburg, HC, 1990) |
| "Indomethacin was utilized in 24 pregnancies (31 exposed fetuses) in preterm labor who labored despite intravenous tocolysis." | 1.28 | Safety and efficacy of long-term tocolysis with indomethacin. ( Abbasi, S; Ashmead, G; Bolognese, R; Gerson, A; Johnson, A; Kalchbrenner, M, 1990) |
| "Indomethacin pretreatment blocked synthesis of both PGF and PGE2 for 30 min following AVT treatment." | 1.28 | Arginine vasotocin-induced prostaglandin synthesis in vitro by the reproductive tract of the viviparous lizard Sceloporus jarrovi. ( Gross, TS; Guillette, LJ; Matter, JH; Palmer, BD, 1990) |
| "These treatments led to pregnancy loss in 89-100% of mice, in contrast to 1% loss in control, vehicle-treated mice." | 1.28 | Activation of maternal killer cells in the pregnant uterus with chronic indomethacin therapy, IL-2 therapy, or a combination therapy is associated with embryonic demise. ( Graham, CH; Lala, PK; Lysiak, JJ; Parhar, RS; Scodras, JM, 1990) |
| "Two women with preeclampsia treated with pindolol and propranolol became profoundly hypertensive when indomethacin was added because of premature contractions." | 1.28 | Antagonism of antihypertensive drug therapy in pregnancy by indomethacin? ( Freedman, S; Hod, M; Ovadia, Y; Schoenfeld, A, 1989) |
| " No differences in the parameters of the dose-response curves between the two IL-1 gene products could be determined (p greater than 0." | 1.28 | Interleukin-1 stimulates prostaglandin biosynthesis by human amnion. ( Dinarello, CA; Durum, S; Hobbins, JC; Mitchell, MD; Oyarzun, E; Romero, R, 1989) |
| "Cloprostenol treatment increased luteal triglycerides and decreased luteal free cholesterol and cholesterol esters within 1 hr after treatment." | 1.27 | Effects of Cloprostenol administration on neutral lipid and prostaglandin F metabolism by porcine luteal tissue. ( Guthrie, HD; Waterman, RA, 1984) |
| "A case of early onset Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis is reported." | 1.27 | A variant of Bartter's syndrome. Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis. ( Akhtar, M; Cumming, W; Ohlsson, A; Serenius, F; Sieck, U, 1984) |
| " Cumulative dose-response curves to oxytocin documented a greater sensitivity in uterine horns from restricted-diet rats than in those from controls or refed animals." | 1.27 | Dietary restriction alters the "in vitro" spontaneous or oxytocin-induced contractions of uterine smooth muscle from estrous rats. Possible participation of prostaglandins. ( Gimeno, AL; Gimeno, MF; Goldraij, A; Sterin, AB, 1983) |
| " Additionally, the data raise questions about the effect of long-term use of nonsteroidal analgesic compounds similar to indomethacin on human reproduction." | 1.27 | Effect of indomethacin on reproduction under laboratory and field conditions in deermice (Peromyscus maniculatus). ( Seeley, RR, 1983) |
| " Cumulative dose-response curves for isoproterenol, norepinephrine and methoxamine were made for the different groups." | 1.27 | In vitro contractile responses of the uterus from 'restricted diet' rats to adrenoceptor agonists. Influence of cyclo-oxygenase inhibitors. ( Gimeno, AL; Gimeno, MA; Goldraij, A; Sterin, AB, 1983) |
| "[14C]Arachidonic acid was converted to several lipoxygenase products by homogenates of human fetal tissues as determined by thin-layer chromatography." | 1.27 | Conversion of arachidonic acid to lipoxygenase products by human fetal tissues. ( Mitchell, MD; Saeed, SA, 1983) |
| "The indomethacin effect on FB was observed in all fetuses tested including those deprived of peripheral chemoreceptor function, vagotomy, decortication, or spinal cord section at the T1 level." | 1.27 | Indomethacin-induced fetal breathing: mechanism and site of action. ( Chernick, V; De Boeck, C; Ioffe, S; Jansen, AH, 1984) |
| "A total of 43 procedures was performed." | 1.27 | Fetal surgery in the primate II. Uterine electromyographic response to operative procedures and pharmacologic agents. ( Harrison, MR; Nakayama, DK; Seron-Ferre, M; Villa, RL, 1984) |
| "Metyrapone was also a relaxant agent, and its action was greater at low than at high PO2." | 1.27 | Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus. ( Coceani, F; Hamilton, NC; Labuc, J; Olley, PM, 1984) |
| "The delay of premature labor for 2 to 7 days allowed the administration of betamethasone in an attempt to improve fetal lung maturity." | 1.27 | Further study of the inhibition of premature labor by indomethacin. Part I. ( Gilad, G; Katzuni, E; Shalev, E; Zuckerman, H, 1984) |
| "Indomethacin treatment of donor rabbits (10 mg/kg s." | 1.27 | Site of action of indomethacin on implantation in the rabbit. ( Harper, MJ; Snabes, MC, 1984) |
| "1) Indomethacin (i." | 1.27 | [The effect of indomethacin on placental permeability and the fetal lung circulation]. ( Chimura, T; Fujimori, K, 1983) |
| "The glomerular lesions of preeclampsia consist of swelling of endothelial cells, interposition of mesangial cells and matrix between the endothelial cells and the glomerular basement membrane, and organization of subendothelial deposits of incompletely characterized material." | 1.27 | Accumulation of several basement membrane proteins in glomeruli of patients with preeclampsia and other hypertensive syndromes of pregnancy. Possible role of renal prostaglandins and fibronectin. ( Bariety, J; Foidart, JB; Foidart, JM; Lambotte, R; Lapiere, CM; Mahieu, PR; Nochy, D; Nusgens, B, 1983) |
| "A case of polyhydramnios associated with a ring chromosome is described." | 1.27 | Polyhydramnios associated with a ring chromosome and low maternal serum alpha-fetoprotein levels managed with indomethacin. ( Cotton, DB; Kirshon, B, 1988) |
| "Appropriate management of preterm labor mandates early recognition of subtle signs and symptoms; successful therapy is dependent on this issue." | 1.27 | Preterm labor: its diagnosis and management. ( Creasy, RK; Gonik, B, 1986) |
| "Indomethacin (Id) treatment of rabbits at the time of implantation resulted in a significant reduction in the number of viable embryos as well as significant reduction in plasma progesterone concentrations." | 1.27 | Treatment with prostaglandins reduces the antifertility effect of indomethacin in rabbits. ( el-Banna, AA, 1986) |
| "Treatment with indomethacin reversed the IFN-gamma defect with most CBL tested, and the addition of physiologic amounts of PGE2 to indomethacin-treated cultures resulted in a profound impairment of IFN-gamma production similar to that of untreated CBL cultures." | 1.27 | Defective IFN-gamma production in the human neonate. II. Role of increased sensitivity to the suppressive effects of prostaglandin E. ( Arenzana-Seisdedos, F; Fiers, W; Huerta, JM; Rothhut, B; Russo-Marie, F; Virelizier, JL; Wakasugi, N, 1985) |
| " The dosage regimen was 25 mg every four hours in four patients and 25 mg every six hours in the other four patients." | 1.27 | Influence of short-term indomethacin therapy on fetal urine output. ( Huhta, JC; Kirshon, B; Moise, KJ; Ou, CN; Wasserstrum, N, 1988) |
| " At the dosage and duration administered, these maternal and fetal hemodynamic and fetal acid-base changes occurred independently of any effect upon uterine blood flow." | 1.27 | Effects of indomethacin on the acid-base balance and hemodynamics of chronically instrumented pregnant sheep. ( Ayromlooi, J; Steele, A, 1988) |
| "The bradykinin response was not mediated by angiotensin II, because bradykinin-induced vasoconstriction was not inhibited by saralasin, a competitive angiotensin antagonist." | 1.27 | Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta. ( Mento, PF; Wilkes, BM, 1988) |
| "Indomethacin is a potent agent in the treatment of premature labor, but its use has been limited because of concern about its constrictive effects on the fetal ductus arteriosus." | 1.27 | Indomethacin in the treatment of premature labor. Effects on the fetal ductus arteriosus. ( Cano, L; Huhta, JC; Kirshon, B; Moise, KJ; Ou, CN; Sharif, DS; Wasserstrum, N, 1988) |
| "Indomethacin pretreatment resulted in attenuation, but not suppression of contractile activity." | 1.27 | Effects of prazosin and indomethacin on the alpha-adrenergic stimulation of rabbit myometrium. ( Barss, VA; Phillippe, M; Valles, L, 1988) |
| "Pretreatment with indomethacin heightened the angiotensin pressor effect significantly in the pregnant group (p = 0." | 1.27 | The interaction between serotonin and angiotensin II in the chronically instrumented guinea pig and its alteration by indomethacin. ( Chestnut, D; Hdez, M; Herrig, J; Wang, JP; Weiner, C, 1987) |
| "Indomethacin has been tested, in addition to betasympathicomimetic therapy, in cases with an insufficient inhibition of premature labour." | 1.27 | Inhibition of premature labour with indomethacin. ( Halle, H, 1987) |
| " Dose-response curves were studied at 4 h following administration of indomethacin on the 19th, 20th, and 21st days, and flurbiprofen on the 20th and 21st days." | 1.27 | In vivo constriction of the ductus arteriosus by nonsteroidal antiinflammatory drugs in near-term and preterm fetal rats. ( Momma, K; Takao, A, 1987) |
| "Issues of the pharmacologic therapy of preterm labor, enhancement of lung maturity, and management of labor and delivery are discussed." | 1.27 | Obstetric management of the very low birth weight fetus. ( Hayashi, RH; Marshall, CL, 1986) |
| "A case of hydrops fetalis with intra-uterine death after premature closure of the ductus arteriosus because of inhibition of premature labour by the administration of indomethacin is presented." | 1.27 | Premature closure of the ductus arteriosus causing intra-uterine death. A case report. ( Coetzee, MJ; Franszen, S; Truter, PJ; van der Merwe, JV, 1986) |
| "Indomethacin was administered to mice on various days of pregnancy, and then the number of implantation sites and the uterine weight per the number of implantation sites were determined on day 10 of pregnancy." | 1.27 | [The effect of indomethacin on the implantation and metabolism of blastocysts]. ( Chida, S; Hoshiai, H; Uehara, S; Yohkaichiya, T, 1985) |
| "Indomethacin treatment by 6h30 after administration of an ovulatory LH dose significantly increased the occurrence of LUF at the expense of POCL." | 1.27 | Prostaglandins involvement in the formation of luteinized unruptured follicles in the cyclic female rat. ( Aron, C; Kauffmann, MT; Plas-Roser, S, 1985) |
| "Preeclampsia is characterized by increased vasoconstriction frequently associated with increased platelet aggregation, reduced uteroplacental blood flow, and premature delivery." | 1.27 | Preeclampsia: an imbalance in placental prostacyclin and thromboxane production. ( Walsh, SW, 1985) |
| "However, the effect of hypoxemia on renal hemodynamics differed between intact and denervated kidneys." | 1.27 | Effects of renal denervation on renal responses to hypoxemia in fetal lambs. ( DiBona, GF; Nakamura, KT; Robillard, JE, 1986) |
| "Indomethacin treatment was also shown to potentiate the action of estradiol." | 1.27 | Structural and functional studies of myometrial gap junctions. ( Cole, WC; Garfield, RE; MacKenzie, LW, 1985) |
| "Despite the reduction in leukocytosis, implantation was prevented by the high dose of indomethacin." | 1.27 | Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat. ( Hurst, PR; Peplow, PV, 1985) |
| "Pretreatment with indomethacin abolished uterine contractions except on day 9 of the cycle, when progesterone levels are at their highest." | 1.27 | Influence of ovarian steroids on prostaglandin- and leukotriene-induced uterine contractions. ( Carraher, RP; Demers, LM; Hahn, DW; McGuire, JL, 1985) |
| " The dose-response relationships between these PGs and decidualization did not differ." | 1.27 | Evidence for the involvement of prostaglandins throughout the decidual cell reaction in the rat. ( Kennedy, TG, 1985) |
| "3) Analysis of 263 cases of threatened premature labor treated in our department in the past 5 years demonstrated that there are 2 phases of contraction during premature labor." | 1.26 | The treatment of threatened premature labor by drugs. ( Chimura, T, 1980) |
| "He appeared to suffer from Bartter's syndrome, a disease characterized by hyperreninemia, hyperaldosteronism and excess prostaglandin production resulting in hypokalemia, normotension, impaired urine concentration ability, polyuria and renal sodium loss." | 1.26 | Hydramnios and observations in Bartter's syndrome. ( Hasaart, T; Rodrigues Pereira, R, 1982) |
| "The chronic use of prostaglandin synthetase inhibitors is reported in a pregnant patient with severe juvenile rheumatoid arthritis." | 1.26 | Oligohydramnios and transient neonatal anuria: a possible association with the maternal use of prostaglandin synthetase inhibitors. ( Cantor, B; Nelson, RM; Stein, GH; Tyler, T, 1980) |
| "Indomethacin treatment of rats during early pregnancy caused a delay in implantation, a significant reduction in uterine weight, and a much reduced number or absence of implanted blastocysts in the uterus on Day 9." | 1.26 | Studies on the involvement of prostaglandins in implantation in the rat. ( Phillips, CA; Poyser, NL, 1981) |
| "Acemetacin was tolerated better than indometacin in all cases." | 1.26 | [Toxicology of acemetacin]. ( Dell, HD; Jacobi, H, 1980) |
| "Indomethacin-treated animals had an increased saccular wall mass, decreased airspace mass, and a decreased capillary to saccular wall ratio (P less than 0." | 1.26 | Effects of indomethacin on fetal rat lungs: a possible cause of persistent fetal circulation (PFC). ( Bloor, CM; Friedman, WF; Harker, LC; Kirkpatrick, SE, 1981) |
| "Treatment with indomethacin alone or indomethacin plus dexamethasone prolonged gestation and prevented an increase in PGF2 alpha-M and a decrease in progesterone." | 1.26 | Effect of indomethacin dexamethasone-induced parturition in swine. ( First, NL; Nara, BS, 1981) |
| "Indomethacin was not teratologic, not cytotoxic to cells in the embryonic hindlimb bud, and did not cross the placenta in physiologically significant amounts on days 11 to 12 of gestation." | 1.26 | Indomethacin--placental transfer, cytotoxicity, and teratology in the rat. ( Clark, KE; Klein, KL; Scott, WJ; Wilson, JG, 1981) |
| "[14C]Indomethacin was injected as a bolus into the fetal hindlimb vein of eight chronically catheterized, near-term ewes and fetuses." | 1.26 | The measurement of placental drug clearance in near-term sheep: indomethacin. ( Anderson, DF; Phernetton, TM; Rankin, JH, 1980) |
| "Indomethacin treatment was effective in all the 68 patients." | 1.26 | Classification of threatened premature labor related to treatment with a prostaglandin inhibitor: indomethacin. ( Abramovici, H; Atad, J; David, A; Moise, J, 1980) |
| " Parallel dose-response curves to bradykinin were observed in the presence of increasing amounts of indomethacin." | 1.26 | Indomethacin in low concentration potentiates the actions of some spasmogens on the isolated oestrous rat uterus. ( Sharma, JN; Zeitlin, IJ, 1977) |
| "Indomethacin has minimal effect upon the first component." | 1.26 | Prostaglandins and regulation of the pulmonary circulation in the perinatal period. ( Cassin, S; Leffler, CW; Tyler, TL, 1977) |
| "Indomethacin has been most effective but not free of significant complications." | 1.26 | Premature onset of labor, neonatal patent ductus arteriosus, and prostaglandin synthetase antagonists--a rat model of a human problem. ( Altmiller, DH; Altshuler, G; Krous, HF; Sharpe, GL, 1979) |
| "Indomethacin did not inhibit T4 response suggesting that T4 stimulation of bone resorption was not mediated by increased prostaglandin synthesis by the cultured bone." | 1.26 | Direct stimulation of bone resorption by thyroid hormones. ( Bandelin, JG; Canalis, EM; Mundy, GR; Raisz, LG; Shapiro, JL, 1976) |
| "When indomethacin was added to the myometrial extracts, the activity of the high Km phosphodiesterase was competitively inhibited, with an average Ki of 200 muM; the low Km enzyme was noncompetitively inhibited with an average Ki of 110 muM." | 1.26 | Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys. ( Beatty, CH; Bocek, RM; Novy, MJ; Young, MK, 1976) |
| "Indomethacin pretreatment completely blocked the oil stimulated DCR as well as all prostaglandin increases following either stimulus." | 1.26 | Uterine prostaglandin levels following stimulation of the decidual cell reaction: effects of indomethacin and tranylcypromine. ( Baggett, B; Jonsson, HT; Ledford, BE; Rankin, JC, 1979) |
| "Indomethacin was present in fetal blood, and maternal plasma prostaglandin levels were suppressed." | 1.26 | Constriction of the fetal ductus arteriosus after administration of indomethacin to the pregnant ewe. ( Campbell, W; Garriott, J; Levin, DL; Mills, LJ; Parkey, M, 1979) |
| "Indomethacin (12 mg/kg) was given to nine fetuses, and observations were made in the control condition and at 15, 120, and 240 min." | 1.26 | Ovine placental vascular responses to indomethacin. ( Anderson, D; Berssenbrugge, A; Phernetton, T; Rankin, JH, 1979) |
| "Fetal hypoxemia, induced by delivering a hypoxic gas mixture to the ewe, was characterized by a reduction in fetal PaO2 from 20." | 1.26 | Prostaglandin control of the renal circulation in response to hypoxemia in the fetal lamb in utero. ( Baig, H; Millard, RW; Vatner, SF, 1979) |
| "Indomethacin was administered from the 20th to the 34th week of gestation to 51 women (59 fetuses) in whom bed rest and a beta-mimetic compound (ritodrine) had failed to stop preterm labor." | 1.26 | Perinatal hazards of chronic antenatal tocolysis with indomethacin. ( Baele, G; Derom, R; Thiery, M; Van Egmond, H; Van Kets, H, 1979) |
| "Indomethacin treatment did not terminate pregnancy: the proportion of animals pregnant on Days 5, 7, 10 and 16 was not affected, although fetal mortality was slightly greater in these animals." | 1.26 | The importance of prostaglandin synthesis for the initiation of blastocyst implantation in the hamster. ( Evans, CA; Kennedy, TG, 1978) |
| "Indomethacin was given by gavage on Days 3-6." | 1.26 | Effects of relaxin on early pregnancy in rats. ( Butler, MC; O'Byrne, EM; Sawyer, WK; Steinetz, BG, 1976) |
| "Indomethacin purportedly arrests premature labor by inhibiting the production of prostaglandins." | 1.26 | Possible association between maternal indomethacin therapy and primary pulmonary hypertension of the newborn. ( Manchester, D; Margolis, HS; Sheldon, RE, 1976) |
| "The dose-response effect of PGF2alpha on the perfused oviduct of estrous and ovariectomized rabbits was determined." | 1.26 | Dose-response effects of prostaglandin F2alpha on the rabbit oviduct: reproductive endocrine influence and tachyphylaxis. ( Heilman, RD; Strainer, SM, 1976) |
| "Indomethacin treatment did not inhibit or suppress spontaneous or oxytocin-induced contractions, which were of the same intensity in indomethacin-treated as in control rats." | 1.26 | The effect of indomethacin on uterine contractility and luteal regression in pregnant rats at term. ( Chantharaksri, U; Fuchs, AR; Smitasiri, Y, 1976) |
| "Formaldehyde 7-." | 1.26 | Efficacy of various locally applied chemicals as contragestational agents in rats. ( Blake, DA; Burnett, LS; Conner, EA; King, TM; Parmley, TH, 1976) |
| "Prevention of premature labor is of considerable interest in research and clinics." | 1.25 | The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs. ( Mosler, KH, 1975) |
| "Metyrapone was approximately 150 times less potent than indomethacin." | 1.25 | The influence of metyrapone on the synthesis and release of prostaglandins from the pregnant rat uterus in vitro. ( Parnham, MJ; Sneddon, JM, 1975) |
| " Six mature female monkeys were treated with HMG-HCG for at least 2 control ovulatory cycles at dosage levels adjusted to induced ovulation while avoiding superovulation." | 1.25 | The effect of indomethacin of HMG-HCG induced ovulation in the phesus monkey. ( Cruz, A; Hunt, J; Stevens, VC; Wallach, EE; Wright, KH, 1975) |
| "Treatment with indomethacin significantly prolonged the length of gestation (P smaller than 0-01) compared iwth control, untreated animals." | 1.25 | The effects of dexamethasone and indomethacin on the outcome of pregnancy in the rabbit. ( Challis, JR; Davies, IJ; Ryan, KJ, 1975) |
| " Polyphloretin phosphate at a concentration of 10 mug/ml resulted in complete identity of dioestrus and metoestrus dose-response curves to angiotensin and oxytocin." | 1.25 | Effects of prostaglandin inhibitors on angiotensin, oxytocin and prostaglandin F2 alpha contractile effects on the rat uterus during the oestrous cycle. ( Baudouin-Legros, M; Meyer, P; Worcel, M, 1974) |
| "Treatment with aspirin prolonged induction-abortion time by about 9 hours and treatment with indomethacin by 30 hours." | 1.25 | Letter to the editor: Non steroid anti-inflammatory drugs and pregnancy. ( Tricomi, V; Waltman, R, 1974) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 621 (47.05) | 18.7374 |
| 1990's | 354 (26.82) | 18.2507 |
| 2000's | 184 (13.94) | 29.6817 |
| 2010's | 111 (8.41) | 24.3611 |
| 2020's | 50 (3.79) | 2.80 |
| Authors | Studies |
|---|---|
| Ville, Y | 1 |
| Mustafa, HJ | 1 |
| Krispin, E | 1 |
| Tadbiri, H | 1 |
| Espinoza, J | 2 |
| Shamshirsaz, AA | 2 |
| Nassr, AA | 2 |
| Donepudi, R | 1 |
| Belfort, MA | 4 |
| Cortes, MS | 2 |
| Pederson, N | 1 |
| Harman, C | 1 |
| Turan, OM | 1 |
| Cole, LK | 1 |
| Sparagna, GC | 1 |
| Dolinsky, VW | 1 |
| Hatch, GM | 1 |
| Kramer, KP | 1 |
| Minot, K | 1 |
| Butler, C | 1 |
| Haynes, K | 1 |
| Mason, A | 1 |
| Nguyen, L | 1 |
| Wynn, S | 1 |
| Liebowitz, M | 1 |
| Rogers, EE | 1 |
| Chawla, S | 1 |
| Natarajan, G | 2 |
| Laptook, AR | 3 |
| Chowdhury, D | 2 |
| Bell, EF | 1 |
| Ambalavanan, N | 1 |
| Carlo, WA | 1 |
| Gantz, M | 1 |
| Das, A | 2 |
| Tapia, JL | 1 |
| Harmon, HM | 1 |
| Shankaran, S | 1 |
| Xiong, Z | 1 |
| Pei, S | 1 |
| Zhu, Z | 1 |
| Proença, ICT | 1 |
| Miri, MR | 1 |
| Marinho, JP | 1 |
| Bock, PM | 1 |
| de Abreu, TM | 1 |
| Pinto, MS | 1 |
| Blembeel, AS | 1 |
| Ferreira, AS | 1 |
| Andrades, M | 1 |
| da Rosa Araújo, AS | 1 |
| Funchal, C | 1 |
| Pochmann, D | 1 |
| Dani, C | 1 |
| Mohammad, K | 2 |
| Momin, S | 1 |
| Murthy, P | 1 |
| Zein, H | 1 |
| Scott, JN | 1 |
| Mehrem, AA | 1 |
| Ghosh, A | 1 |
| Javadyan, A | 1 |
| Awad, EA | 1 |
| Venkata, SKRG | 1 |
| Paul, R | 1 |
| Rombough, B | 1 |
| Bolderheij, L | 1 |
| Dossani, S | 1 |
| Montpetit, J | 1 |
| Eshemokhai, P | 1 |
| Fiedrich, E | 1 |
| Thomas, S | 1 |
| Zhu, T | 1 |
| Cao, C | 1 |
| Hossain, MR | 1 |
| Tolosa, JM | 2 |
| Young, RC | 1 |
| Smith, R | 3 |
| Paul, JW | 2 |
| Powel, JE | 1 |
| Kraus, E | 1 |
| Reddy, C | 1 |
| Lannaman, K | 1 |
| Clyman, RI | 18 |
| Hills, NK | 3 |
| Qiu, L | 1 |
| Lv, M | 1 |
| Chen, C | 1 |
| Li, J | 2 |
| Zhao, B | 1 |
| Luo, Q | 1 |
| Saxton, SN | 1 |
| Evered, J | 1 |
| McCoy, K | 1 |
| Atkins, K | 1 |
| Razak, A | 1 |
| Patel, W | 1 |
| Durrani, NUR | 1 |
| Pullattayil, AK | 1 |
| Prakash, E | 1 |
| Pavithra, S | 1 |
| Kishor Kumar, DG | 1 |
| Panigrahi, M | 1 |
| Singh, TU | 1 |
| Kumar, D | 1 |
| Parida, S | 1 |
| Murdoch, I | 1 |
| Carver, AL | 1 |
| Sultan, P | 1 |
| O'Carroll, JE | 1 |
| Blake, L | 1 |
| Carvalho, B | 1 |
| Onwochei, DN | 1 |
| Desai, N | 1 |
| Weydig, H | 1 |
| Brion, LP | 1 |
| Wyckoff, MH | 1 |
| Arnautovic, TI | 2 |
| Younge, N | 1 |
| Oh, W | 3 |
| Keszler, M | 2 |
| Hanke, K | 1 |
| Fortmann, I | 1 |
| Humberg, A | 1 |
| Faust, K | 1 |
| Kribs, A | 1 |
| Prager, S | 1 |
| Felderhoff-Müser, U | 1 |
| Krüger, M | 1 |
| Heckmann, M | 1 |
| Jäger, A | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Control Trial Physical Exam Indicated Cerclage in Twin Gestations[NCT02490384] | 30 participants (Actual) | Interventional | 2015-06-30 | Terminated (stopped due to due to significant decrease of perinatal mortality in the cerclage group) | |||
| Effect of Oral N-Acetyl Cysteine on Pregnancy Outcome After Cervical Cerclage: a Randomized Controlled Trial[NCT00787813] | 100 participants (Anticipated) | Interventional | 2008-06-30 | Completed | |||
| The Effect of Adjunctive Use of Vaginal Progesterone After Cerclage on Prevention of 2nd Trimester Miscarriage[NCT02846909] | Phase 2 | 242 participants (Actual) | Interventional | 2017-04-01 | Completed | ||
| Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening[NCT03837288] | 60 participants (Anticipated) | Interventional | 2019-04-22 | Recruiting | |||
| Pessary as Adjunctive Therapy to Cerclage for the Prevention of Preterm Birth[NCT02678026] | Phase 3 | 0 participants (Actual) | Interventional | 2016-01-01 | Withdrawn (stopped due to no enrollment) | ||
| Investigation of Ibuprofen in the Delay of Ovulation in NC-IVF (Natural Cycle in Vitro Fertilisation) Therapy With the Objective of Reducing Premature Ovulation and Thus Improving Effectivity (Off Label Use)[NCT02571543] | Phase 2 | 68 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Vaginal Indomethacin Versus Oral Nifedipine for Preterm Labor; a Randomized Controlled Trial[NCT04404686] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2020-10-31 | Not yet recruiting | ||
| Comparison of the Efficacy of Emergency Double-level and Single Cervical Cerclage in Cervical Insufficiency in the Second Trimester of Pregnancy - Multicenter Prospective Randomized Trial[NCT05268640] | 78 participants (Anticipated) | Interventional | 2022-03-11 | Recruiting | |||
| Role in Emergent Cerclage of Indomethacin and Antibiotics[NCT01114516] | 53 participants (Actual) | Interventional | 2010-03-31 | Completed | |||
| Prevention of Preterm Delivery With Vaginal Progesterone in Women With Preterm Labor[NCT00536003] | Phase 3 | 384 participants (Actual) | Interventional | 2006-07-31 | Terminated | ||
| Vaginal Progesterone Supplementation in the Management of Preterm Labor: A Randomized, Double Blind, Controlled Trial[NCT03202836] | 90 participants (Actual) | Interventional | 2017-06-29 | Completed | |||
| Randomized, Placebo Controlled Trial of Indomethacin for Tocolysis[NCT01869361] | Early Phase 1 | 0 participants (Actual) | Interventional | 2020-08-01 | Withdrawn (stopped due to Due to much lower than expected numbers of eligible patients and lack of PI time, the study was not started.) | ||
| Aspirin Supplementation for Pregnancy Indicated Risk Reduction In Nulliparas (ASPIRIN)[NCT02409680] | 11,976 participants (Actual) | Interventional | 2016-03-23 | Completed | |||
| Paracetamol (Acetaminophen) for Closure of PDA in Preterm Infants[NCT01755728] | Phase 3 | 19 participants (Actual) | Interventional | 2013-01-01 | Completed | ||
| Comparison of Two Antibiotic Prophylactic Protocols in Preterm Premature Rupture of the Membranes. A Randomized Prospective, Open Trial[NCT02819570] | Phase 4 | 400 participants (Anticipated) | Interventional | 2015-11-30 | Recruiting | ||
| Effect of Acupuncture on Vascular Biomarkers and Psychological Well-Being of Women Undergoing In Vitro Fertilization (IVF)[NCT02591186] | 60 participants (Actual) | Interventional | 2015-11-01 | Completed | |||
| Pilot Study to Examine Iloprost Can Enhance Human Assisted Reproductive Technology Pregnancy Outcomes.[NCT01549171] | 100 participants (Anticipated) | Observational | 2010-01-31 | Recruiting | |||
| Generic Database: A Survey of Morbidity and Mortality in Very Low Birth Weight Infants[NCT00063063] | 80,000 participants (Anticipated) | Observational | 1987-01-31 | Recruiting | |||
| A Scientific & Clinical Review of Minimal Stimulation Protocol Using AROMEK (Letrozole) and Follitrope (Recombinant FSH)Combined With INVOCell(Intravaginal Culturing) - Effectiveness as Low Cost IVF[NCT01058252] | 30 participants (Anticipated) | Observational | 2021-05-31 | Recruiting | |||
| An Open-label, Single-dose, Pharmacokinetic Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Orthodontic Pain[NCT05844995] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | ||
| Randomized Double-Blinded Trial of Magnesium Sulfate Tocolysis Versus Nifedipine Tocolysis in Women With Preterm Labor Between 24 to 32 6/7 Weeks' Gestation[NCT00306462] | 33 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to No enrollment in past year, lack of interest) | |||
| Comparison of the Number of Visits and the Quality of Life Versus Natural Cycle in Stimulated Cycle Before Frozen Embryo Transfer[NCT02834117] | Phase 4 | 124 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Effects of High Altitude on 5' Adenosine Monophosphate-activated Protein Kinase (AMPK) Activation and Peroxisome Proliferator-activated Receptor Gamma (PPARγ) Regulation[NCT02391519] | 84 participants (Anticipated) | Observational | 2016-01-31 | Recruiting | |||
| Randomized Indomethacin Germinal Matrix Hemorrhage/Intraventricular Hemorrhage (GMH/IVH) Prevention Trial[NCT00033917] | Phase 3 | 630 participants (Actual) | Interventional | 1989-09-30 | Completed | ||
| Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
| Effect of Non-steroidal Anti-inflammatory Use on Blood Pressure in Women With Hypertensive Disorders of Pregnancy: A Randomized Open Label Trial[NCT03824119] | Phase 4 | 200 participants (Anticipated) | Interventional | 2018-12-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Median birthweight (NCT01114516)
Timeframe: 24 weeks
| Intervention | grams (Median) |
|---|---|
| Control | 2488 |
| Indomethacin and Antibiotics | 2850 |
Median gestational age at delivery (NCT01114516)
Timeframe: 24 weeks
| Intervention | weeks (Median) |
|---|---|
| Control | 31.1 |
| Indomethacin and Antibiotics | 34.8 |
Median gestational latency achieved Between Cerclage Placement and Time of Delivery (NCT01114516)
Timeframe: 24 weeks
| Intervention | days (Median) |
|---|---|
| Control | 80 |
| Indomethacin and Antibiotics | 97 |
The frequency of achieving a gestational latency of more than 28 days (NCT01114516)
Timeframe: 28 days postpartum
| Intervention | percentage of participants (Number) |
|---|---|
| Control | 62.5 |
| Indomethacin and Antibiotics | 92.3 |
Days spent in the neonatal intensive care unit (NCT01114516)
Timeframe: 1 year
| Intervention | days (Median) |
|---|---|
| Control | 95 |
| Indomethacin and Antibiotics | 43 |
- Early preterm delivery (<34 weeks) (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 189 |
| Placebo Arm | 230 |
- Birth weight <2500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1078 |
| Placebo Arm | 1153 |
- Birth weight <1500g (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 78 |
| Placebo Arm | 101 |
- Incidence of Fetal Loss (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 303 |
| Placebo Arm | 353 |
- Incidence of Spontaneous Abortion (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 134 |
| Placebo Arm | 152 |
- Incidence of All stillbirth (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 141 |
| Placebo Arm | 166 |
- Incidence of Medical Termination of Pregnancy (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 42 |
| Placebo Arm | 30 |
- Hypertensive disorders of pregnancy is defined by the characterization of evidence of a hypertensive disorder, including either preeclampsia or eclampsia occurring during the pregnancy. (NCT02409680)
Timeframe: Evidence of hypertensive disorder during the pregnancy (prior to delivery/birth)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 352 |
| Placebo Arm | 325 |
- Incidence of Perinatal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 264 |
| Placebo Arm | 309 |
The primary outcome of this study is incidence of preterm birth, which will be defined as delivery at or after 20 0/7 weeks and prior to 37 0/7 weeks. This will be determined based on actual date of delivery in comparison to the projected estimated due date (EDD), independent of whether or not the preterm delivery is indicated or spontaneous. (NCT02409680)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 668 |
| Placebo Arm | 754 |
- Small for gestational age (SGA) as defined by the INTERGROWTH-21st standard (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 1506 |
| Placebo Arm | 1564 |
- Vaginal bleeding (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 214 |
| Placebo Arm | 246 |
- Antepartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 26 |
| Placebo Arm | 25 |
- Postpartum hemorrhage (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 54 |
| Placebo Arm | 43 |
- Incidence of Maternal Mortality (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 9 |
| Placebo Arm | 12 |
- Incidence of Late Abortion (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 23 |
| Placebo Arm | 30 |
Hemoglobin < 7.0 gm/dl at 26-30 weeks gestation or a drop of 3.5+ gm/dl from screening to 26-30 weeks gestation (NCT02409680)
Timeframe: At enrollment, 4 weeks post enrollment, and 26-30 weeks GA.
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 290 |
| Placebo Arm | 333 |
Early preterm delivery (<34 weeks) and hypertensive disorders (i.e.: preeclampsia) (NCT02409680)
Timeframe: At delivery or at Day 42 after delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Intervention Arm | 8 |
| Placebo Arm | 21 |
Cranial ultrasounds were performed daily for the first 5 postnatal days; the main outcome measure was intraaventricular hemorrhage (IVH) at 5 days of age (NCT00033917)
Timeframe: at 5 days
| Intervention | IVH (Number) |
|---|---|
| Indomethacin | 25 |
| Placebo | 40 |
"Peabody Picture Vocabulary Test (PPVT) This is a semantic language test. The mean value is 100; standard deviation is 16 points. A higher score means better language; a lower score means poorer language.~There are no subscales to the PPVT. The measurement unit is points on a scale. A score < 70 indicates severely abnormal language function." (NCT00033917)
Timeframe: at 8 years
| Intervention | participants with PPVT score < 70 (Number) |
|---|---|
| Indomethacin - no IVH | 12 |
| Indomethacin - IVH | 5 |
| Placebo - no IVH | 24 |
| Placebo - IVH | 7 |
113 reviews available for indomethacin and Pregnancy
| Article | Year |
|---|---|
Four kinds of tocolytic therapy for preterm delivery: Systematic review and network meta-analysis.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Network Meta-Analysis; Nifedipine; Obstetric | 2022 |
Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates: A Systematic Review and Meta-analysis.
Topics: Adrenal Cortex Hormones; Brain Injuries; Cerebral Hemorrhage; Ethamsylate; Female; Humans; Indometha | 2023 |
Comparison of different nonsteroidal anti-inflammatory drugs for cesarean section: a systematic review and network meta-analysis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cesarean Section; Diclofenac; Female; Humans; In | 2023 |
Current and future role of fetal cardiovascular MRI in the setting of fetal cardiac interventions.
Topics: Anemia; Anti-Inflammatory Agents, Non-Steroidal; Atrial Septum; Blood Transfusion, Intrauterine; Duc | 2020 |
An Overview of Systematic Reviews of Randomized-Controlled Trials for Preventing Necrotizing Enterocolitis in Preterm Infants.
Topics: Administration, Oral; Adrenal Cortex Hormones; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Cervical stitch (cerclage) in combination with other treatments for preventing spontaneous preterm birth in singleton pregnancies.
Topics: Albuterol; Analgesics, Opioid; Anti-Bacterial Agents; Bias; Cefazolin; Cerclage, Cervical; Clindamyc | 2020 |
Advances in Management for Preterm Fetuses at Risk of Delivery.
Topics: Anti-Bacterial Agents; Anticonvulsants; Betamethasone; Dexamethasone; Female; Fetal Membranes, Prema | 2020 |
Prevention of Prematurity: Advances and Opportunities.
Topics: Anti-Infective Agents; Aspirin; Cerclage, Cervical; Cesarean Section; Female; Humans; Indomethacin; | 2018 |
Tocolysis for open prenatal repair of myelomeningocele: systematic review.
Topics: Female; Fetoscopy; Gestational Age; Humans; Indomethacin; Meningomyelocele; Obstetric Labor, Prematu | 2020 |
Prenatal effects of maternal consumption of polyphenol-rich foods in late pregnancy upon fetal ductus arteriosus.
Topics: Constriction; Diet; Ductus Arteriosus; Female; Fetus; Humans; Indomethacin; Maternal Exposure; Polyp | 2013 |
Clinical pharmacology of ibuprofen and indomethacin in preterm infants with patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Dinoprostone; Drug Administration Schedule; Ductus Arteriosus, Patent; Fe | 2014 |
Safety of therapeutics used in management of patent ductus arteriosus in preterm infants.
Topics: Acetaminophen; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen; Indo | 2015 |
Antenatal exposure to indomethacin increases the risk of severe intraventricular hemorrhage, necrotizing enterocolitis, and periventricular leukomalacia: a systematic review with metaanalysis.
Topics: Cerebral Ventricles; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa | 2015 |
Tocolytics used as adjunctive therapy at the time of cerclage placement: a systematic review.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerclage, Cervical; Chemotherapy, Adjuvant; Female; Humans; | 2015 |
Cyclo-oxygenase (COX) inhibitors for treating preterm labour.
Topics: Calcium Channel Blockers; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Magnesium Sulfate | 2015 |
Ibuprofen lysine for the prevention and treatment of patent ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Fetus; Humans; Ib | 2008 |
Understanding intestinal vulnerability to perforation in the extremely low birth weight infant.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Communicable Diseases; Disease Models, Animal; Fem | 2009 |
A short cervical length in pregnancy: management options.
Topics: Cerclage, Cervical; Cervix Uteri; Cohort Studies; Combined Modality Therapy; Female; Humans; Indomet | 2009 |
Acute nephrotoxicity of NSAID from the foetus to the adult.
Topics: Acute Kidney Injury; Adult; Age Factors; Anti-Inflammatory Agents, Non-Steroidal; Child; Female; Hum | 2011 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
Tocolytic therapy for acute preterm labor.
Topics: Calcium Channel Blockers; Drug Administration Schedule; Female; Gestational Age; Humans; Indomethaci | 2012 |
The ductus arteriosus: a refined approach!
Topics: Biomarkers; Cyclooxygenase Inhibitors; Decision Making; Ductus Arteriosus, Patent; Echocardiography; | 2012 |
Managing the patent ductus arteriosus in the premature neonate: a new look at what we thought we knew.
Topics: Acetaminophen; Biomarkers; Dose-Response Relationship, Drug; Ductus Arteriosus, Patent; Echocardiogr | 2012 |
Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Inf | 2012 |
Segmental absence of intestinal musculature: an increasingly reported pathology.
Topics: Abdomen, Acute; Abnormalities, Multiple; Adult; Cesarean Section; Digestive System Abnormalities; Du | 2012 |
Oral betamimetics for maintenance therapy after threatened preterm labour.
Topics: Administration, Oral; Adrenergic beta-2 Receptor Agonists; Female; Humans; Indomethacin; Magnesium C | 2012 |
[Tocolysis: indications and contraindications. When to start and when to stop].
Topics: Clinical Trials as Topic; Contraindications; Female; France; Gestational Age; Humans; Indomethacin; | 2002 |
Prostaglandin inhibitors in preterm labour.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cervix Uteri; Cyclooxygenase 2; Ductus Arteriosus; Enzyme I | 2003 |
Assessing the neonatal safety of indomethacin tocolysis: a systematic review with meta-analysis.
Topics: Adult; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2005 |
Assessing the neonatal safety of indomethacin tocolysis: a systematic review with meta-analysis.
Topics: Adult; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2005 |
Assessing the neonatal safety of indomethacin tocolysis: a systematic review with meta-analysis.
Topics: Adult; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2005 |
Assessing the neonatal safety of indomethacin tocolysis: a systematic review with meta-analysis.
Topics: Adult; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; | 2005 |
Antiprostaglandin drugs.
Topics: Cyclooxygenase Inhibitors; Female; Fetal Monitoring; Humans; Indomethacin; Obstetric Labor, Prematur | 2005 |
Oral betamimetics for maintenance therapy after threatened preterm labour.
Topics: Administration, Oral; Adrenergic beta-Agonists; Female; Humans; Indomethacin; Obstetric Labor, Prema | 2006 |
Nonsteroidal antiinflammatory drugs during third trimester and the risk of premature closure of the ductus arteriosus: a meta-analysis.
Topics: Abnormalities, Drug-Induced; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus; Female; Hum | 2006 |
Short cervix on ultrasound: does indomethacin prevent preterm birth?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cervix Uteri; Female; Fetal Membranes, Premature Rupture; H | 2006 |
Preterm labour. The present and future of tocolysis.
Topics: Adrenergic beta-Agonists; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric Lab | 2007 |
Metaanalysis of the effect of antenatal indomethacin on neonatal outcomes.
Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant | 2007 |
Prenatal and perinatal factors influencing nociception, addiction and behavior during ontogenetic development.
Topics: Animals; Animals, Newborn; Behavior, Addictive; Behavior, Animal; Dexamethasone; Female; Humans; Ind | 2008 |
Prevention of premature birth.
Topics: Adrenergic beta-Agonists; Calcium; Chemical Phenomena; Chemistry; Cyclooxygenase Inhibitors; Depress | 1980 |
Prostaglandins and the ductus arteriosus.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blood Vessels; Cyclooxygenase Inhibitors; Dinoprost; D | 1982 |
Control of vascular responsiveness during human pregnancy.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Aspirin; Blood Vessels; Cyclic AMP; Female; Humans; Hy | 1980 |
Review: prostaglandins in diarrheal states.
Topics: Aspirin; Bacterial Infections; Child; Cholera Toxin; Colonic Diseases; Cyclic AMP; Diarrhea; Dinopro | 1981 |
Drug therapy in autoimmune diseases.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Adrenal Cortex Hormones; Autoimmune Diseases; Azathiopri | 1983 |
A reexamination of the role of oxygen in retrolental fibroplasia.
Topics: Anencephaly; Apnea; Carbon Dioxide; Cerebral Hemorrhage; Ductus Arteriosus, Patent; Exchange Transfu | 1984 |
Pharmacokinetics of inhibitors of prostaglandin synthesis in the perinatal period.
Topics: Adolescent; Adult; Aging; Animals; Child; Child, Preschool; Cyclooxygenase Inhibitors; Female; Fetus | 1980 |
Preterm parturition. Prostaglandin synthetase inhibitors.
Topics: Amniotic Fluid; Animals; Aspirin; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, P | 1981 |
Interaction of nicotine and prostaglandins in the cardiovascular system.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Platelets; Cardiov | 1982 |
Drug therapy: nonsteroidal antiinflammatory drugs (first of two parts).
Topics: Anti-Inflammatory Agents; Arthritis; Aspirin; Child; Drug Tolerance; Female; Gastric Mucosa; Gastrit | 1980 |
Role of prostaglandins and thromboxanes in the control of the pulmonary circulation in the fetus and newborn.
Topics: Aging; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Epoprostenol; Female; Fetus; Hum | 1980 |
Role of prostaglandins, prostacyclin, and thromboxanes in the control of prenatal patency and postnatal closure of the ductus arteriosus.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Ductus Arteriosus; Ductus Arteriosus, P | 1980 |
Ontogeny of the ductus arteriosus response to prostaglandins and inhibitors of their synthesis.
Topics: Animals; Arachidonic Acids; Ductus Arteriosus; Epoprostenol; Female; Fetus; Gestational Age; Humans; | 1980 |
The inhibition of prostaglandin and prostacyclin synthesis in the clinical management of patent ductus arteriosus.
Topics: Ductus Arteriosus, Patent; Epoprostenol; Female; Humans; Indomethacin; Infant, Low Birth Weight; Inf | 1980 |
Effects of prostaglandins, thromboxanes, and inhibitors of their synthesis on renal and gastrointestinal function in the newborn period.
Topics: Adult; Animals; Digestive System Physiological Phenomena; Ductus Arteriosus, Patent; Female; Humans; | 1980 |
Role of prostaglandins, prostacyclin, and thromboxanes in the control of the umbilical-placental circulation.
Topics: Angiotensin II; Animals; Epoprostenol; Estrogens; Female; Humans; Indomethacin; Muscle, Smooth; Plac | 1980 |
Effects of inhibition of prostaglandin synthesis on fetal development, oxygenation, and the fetal circulation.
Topics: Animals; Blood Circulation; Ductus Arteriosus; Female; Fetal Blood; Fetus; Humans; Hypertension, Pul | 1980 |
Naproxen sodium (Anaprox): pharmacology, pharmacokinetics and drug interactions.
Topics: Acid-Base Equilibrium; Animals; Chemical Phenomena; Chemistry; Depression, Chemical; Drug Interactio | 1980 |
An overview of perinatal clinical pharmacology.
Topics: Abnormalities, Drug-Induced; Analgesics; Bupivacaine; Carbamazepine; Chloramphenicol; Diazepam; Digo | 1981 |
Prevention of intraventricular hemorrhage in preterm infants.
Topics: Adrenal Cortex Hormones; Cerebral Hemorrhage; Delivery, Obstetric; Female; Humans; Indomethacin; Inf | 1995 |
[Hydramnios. Etiology, diagnosis and possible therapy].
Topics: Amniocentesis; Amniotic Fluid; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Polyh | 1995 |
Patent ductus arteriosus. Clinical relevance of prostaglandins and prostaglandin inhibitors in PDA pathophysiology and treatment.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, | 1995 |
Fetal therapy.
Topics: Amniocentesis; Drainage; Embolization, Therapeutic; Female; Fetofetal Transfusion; Fetus; Humans; In | 1994 |
Treatment of polyhydramnios with indomethacin.
Topics: Amniotic Fluid; Contraindications; Cyclooxygenase Inhibitors; Female; Fetal Monitoring; Fetus; Human | 1994 |
Effect of drugs on the immature kidney.
Topics: Angiotensin-Converting Enzyme Inhibitors; Dopamine Agents; Female; Fetus; Furosemide; Humans; Indome | 1993 |
The control of the ductus venosus: an update.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Infant, Newborn; Por | 1993 |
The fetal ductus arteriosus, a review.
Topics: Betamethasone; Blood Flow Velocity; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; In | 1993 |
Prostaglandin synthetase inhibitors in pregnancy.
Topics: Animals; Contraindications; Cyclooxygenase Inhibitors; Female; Fetal Diseases; Forecasting; Humans; | 1993 |
Polyhydramnios: problems and treatment.
Topics: Amniocentesis; Female; Fetal Diseases; Humans; Incidence; Indomethacin; Polyhydramnios; Pregnancy; T | 1993 |
[Antenatal form of Bartter's syndrome].
Topics: Aldosterone; Bartter Syndrome; Calcium; Female; Fetal Diseases; Gestational Age; Humans; Indomethaci | 1993 |
Indomethacin.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Female; Humans; Indomethacin; Obs | 1995 |
Risks and complications of tocolysis.
Topics: Calcium Channel Blockers; Drug Therapy, Combination; Female; Fetus; Humans; Indomethacin; Magnesium | 1995 |
Polyhydramnios.
Topics: Amniocentesis; Cyclooxygenase Inhibitors; Female; Humans; Incidence; Indomethacin; Polyhydramnios; P | 1997 |
Teratogen update: fetal effects of indomethacin administration during pregnancy.
Topics: Adult; Animals; Anti-Inflammatory Agents, Non-Steroidal; Embryonic and Fetal Development; Female; Ge | 1997 |
[Prematurity: current role of prostaglandin synthesis inhibitors].
Topics: Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Preg | 1998 |
The great tocolytic debate: some pitfalls in the study of safety.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; MEDLINE; Obstetric Labor, Premature; Pregnancy; R | 2001 |
NSAID-induced nephrotoxicity from the fetus to the child.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Ductus Arteriosus, Patent; Female; | 2001 |
The controversy surrounding indomethacin for tocolysis.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Pre | 2001 |
Prostaglandin inhibitors as tocolytic agents.
Topics: Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; | 2001 |
Tocolysis: an update for the practitioner.
Topics: Adrenergic beta-Agonists; Algorithms; Calcium Channel Blockers; Cyclooxygenase 1; Cyclooxygenase 2; | 2002 |
Antiinflammatory drugs.
Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Chi | 1977 |
Drugs for inhibition of premature labor.
Topics: Adrenergic beta-Agonists; Animals; Ethanol; Female; Humans; Indomethacin; Labor, Obstetric; Magnesiu | 1979 |
Vascular reactivity to angiotensin II in human pregnancy.
Topics: Adolescent; Angiotensin II; Animals; Aspirin; Blood Pressure; Blood Volume; Dogs; Female; Haplorhini | 1978 |
Contractility of the fallopian tube.
Topics: Animals; Bucladesine; Castration; Depression, Chemical; Estrus; Fallopian Tubes; Female; Guinea Pigs | 1975 |
[Clinical pharmacology in obstetrics: regulation of the uterus].
Topics: Adrenergic beta-Agonists; Aspirin; Ergotamine; Female; Humans; Indomethacin; Methylergonovine; Obste | 1975 |
Role of naturally occurring vasoactive principles in hypertension. State of the art.
Topics: Animals; Blood Vessels; Dogs; Female; Humans; Hypertension; Indomethacin; Kallikreins; Kidney; Kidne | 1977 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indome | 1978 |
Prostaglandins: physiological and clinical correlations.
Topics: Animals; Autonomic Nervous System; Blood Circulation; Cricetinae; Dogs; Ductus Arteriosus, Patent; F | 1978 |
The patent ductus arteriosus.
Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent | 1978 |
[New aspects of the pathophysiology of gestosis/pre-eclampsia (author's transl)].
Topics: Angiotensin II; Blood Pressure; Bradykinin; Dopamine; Eclampsia; Female; Humans; Indomethacin; Kalli | 1979 |
[Kidney and pregnancy].
Topics: Acute Kidney Injury; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Chloramphenicol; Creatin | 1976 |
Uterine luteolytic hormone: a physiological role for prostaglandin F2alpha.
Topics: Animals; Cattle; Corpus Luteum; Dogs; Estrogens; Female; Guinea Pigs; Humans; Indomethacin; Labor, O | 1976 |
Prostaglandin F2alpha is the uterine luteolytic hormone in the guinea pig: the evidence reviewed.
Topics: Animals; Antibodies; Antigen-Antibody Reactions; Castration; Estradiol; Estrus; Female; Foreign-Body | 1976 |
[Fetal toxicity of non-steroidal anti-inflammatory agents].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Fetal Diseases; Heart Failure; Humans; Indomethacin | 1992 |
Principles and applications of manipulation of prostaglandin synthesis in pregnancy.
Topics: Aspirin; Diet; Dietary Fats; Epoprostenol; Fatty Acids, Unsaturated; Female; Humans; Indomethacin; P | 1992 |
Ductus-dependent fetal cardiac defects contraindicate indomethacin tocolysis.
Topics: Adult; Aortic Valve Stenosis; Contraindications; Ductus Arteriosus; Ductus Arteriosus, Patent; Femal | 1992 |
Polyhydramnios: does reducing the amniotic fluid volume decrease the incidence of prematurity?
Topics: Amniocentesis; Clinical Trials as Topic; Combined Modality Therapy; Female; Humans; Incidence; Indom | 1992 |
Endothelium-derived vasoactive substances and uterine blood vessels.
Topics: Angiotensin II; Animals; Cyclic AMP; Cyclic GMP; Endothelium, Vascular; Epoprostenol; Female; Hemody | 1991 |
Indomethacin therapy in the treatment of symptomatic polyhydramnios.
Topics: Female; Humans; Indomethacin; Polyhydramnios; Pregnancy | 1991 |
Antenatal therapy to minimize neonatal intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant, Newborn; Phenobarbital; Pregnancy; Prenat | 1991 |
Human placental acetylcholine.
Topics: Acetylcholine; Amino Acids; Atropine; Female; Humans; Indomethacin; Placenta; Pre-Eclampsia; Pregnan | 1991 |
Maternal, fetal, and neonatal physiology in pregnancy.
Topics: Clinical Trials as Topic; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Obstetric Labor, | 1990 |
Interruption of murine pregnancy by activation of antigen-non-specific killer cells in the endometrium with indomethacin, high dose IL-2 or a combination.
Topics: Abortion, Spontaneous; Animals; Drug Synergism; Endometrium; Female; G(M1) Ganglioside; Glycosphingo | 1990 |
[Indomethacin and a tocolytic agent: fetal and neonatal outcome].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Premature; Pregnancy; Prenatal | 1990 |
Arachidonic acid derivatives in the perinatal period.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Heart Defects, Congenital; Humans; Indomethaci | 1989 |
Prostaglandins and leukotrienes in the perinatal period.
Topics: Ductus Arteriosus; Female; Heart Defects, Congenital; Humans; Indomethacin; Infant, Newborn; Leukotr | 1987 |
Control of time of parturition in pigs.
Topics: Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animal Husbandry; Animals; Dinoprost; Fema | 1985 |
Adverse effects of drugs on the immature kidney.
Topics: Adrenergic beta-Agonists; Angiotensin-Converting Enzyme Inhibitors; Female; Fetus; Furosemide; Glome | 1988 |
[At what point is premature labor to be arrested?].
Topics: Adrenergic beta-Agonists; Female; Humans; Indomethacin; Magnesium Sulfate; Obstetric Labor, Prematur | 1987 |
Oligohydramnios, renal insufficiency, and ileal perforation in preterm infants after intrauterine exposure to indomethacin.
Topics: Amniotic Fluid; Female; Gastrointestinal Hemorrhage; Humans; Ileal Diseases; Indomethacin; Infant, L | 1988 |
Prostaglandins, renin-angiotensin system, and hypertension.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Blood Pressure; Dinoprostone; Female; Humans; | 1985 |
[Value and dangers of indomethacin used in pregnancy. Apropos of 304 treated patients].
Topics: Abortion, Threatened; Acute Kidney Injury; Ductus Arteriosus, Patent; Female; Fetal Death; Fetus; Hu | 1988 |
Drug therapy in hypoxic-ischemic cerebral insults and intraventricular hemorrhage of the newborn.
Topics: Asphyxia Neonatorum; Barbiturates; Brain Ischemia; Cerebral Hemorrhage; Female; Fetal Hypoxia; Human | 1987 |
Antirheumatic medication in pregnancy.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Anti-Inflammatory Agents; Antineoplas | 1985 |
Endogenous prostaglandins and the initiation of labor.
Topics: Amniotic Fluid; Animals; Birth Weight; Depression, Chemical; Female; Gestational Age; Haplorhini; Hu | 1974 |
[Osteitis condensans ilii].
Topics: Adult; Age Factors; Diagnosis, Differential; Female; Hot Temperature; Humans; Ilium; Indomethacin; M | 1974 |
Prostaglandins in the control of ovulation, corpus luteum function, and parturition.
Topics: Animals; Aspirin; Corpus Luteum; Cricetinae; Estrogens; Female; Haplorhini; Humans; Hysterectomy; In | 1973 |
[Present position of the toxicology of drugs].
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amantadine; Aminopterin; Animals; Animals, Newbo | 1970 |
71 trials available for indomethacin and Pregnancy
| Article | Year |
|---|---|
Physical examination-indicated cerclage in twin pregnancy: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Asymptomatic Diseases; Cerclage, Cervical; Cervical Length Measurement | 2020 |
The effectiveness of nifedipine/indomethacin combination therapy and nifedipine monotherapy for postponing preterm birth (25-34 weeks of gestation) in Sudanese women: a randomized clinical trial study protocol.
Topics: Adolescent; Adult; Combined Modality Therapy; Female; Gestational Age; Humans; Indomethacin; Infant, | 2021 |
A comparative study on the efficacy of nifedipine and indomethacin for prevention of preterm birth as monotherapy and combination therapy: a randomized clinical trial.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregn | 2020 |
[A random control study of indomethacin-containing MYCu intrauterine contraceptive device for 60 months].
Topics: Adult; Female; Humans; Indomethacin; Intrauterine Devices; Intrauterine Devices, Copper; Pregnancy; | 2013 |
Effectiveness of indometacin to prevent ovulation in modified natural-cycle IVF: a randomized controlled trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Fertilization in Vitro; | 2013 |
A comparison of three tocolytics for preterm labor: a randomized clinical trial.
Topics: Adolescent; Adult; Drug Administration Routes; Female; Gestational Age; Humans; Indomethacin; Magnes | 2014 |
Pharmacokinetics of indomethacin in pregnancy.
Topics: Administration, Oral; Adolescent; Adult; Area Under Curve; Chromatography, High Pressure Liquid; Fem | 2014 |
A comparative study on relieving post-episiotomy pain with diclofenac and indomethacin suppositories or placebo.
Topics: Administration, Rectal; Adolescent; Adult; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Metho | 2014 |
Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Cefaz | 2014 |
Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Cefaz | 2014 |
Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Cefaz | 2014 |
Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Cefaz | 2014 |
Prevention of preterm delivery with vaginal progesterone in women with preterm labour (4P): randomised double-blind placebo-controlled trial.
Topics: Administration, Intravaginal; Adult; Apgar Score; Birth Weight; Double-Blind Method; Female; Humans; | 2015 |
Prevention of preterm delivery with vaginal progesterone in women with preterm labour (4P): randomised double-blind placebo-controlled trial.
Topics: Administration, Intravaginal; Adult; Apgar Score; Birth Weight; Double-Blind Method; Female; Humans; | 2015 |
Prevention of preterm delivery with vaginal progesterone in women with preterm labour (4P): randomised double-blind placebo-controlled trial.
Topics: Administration, Intravaginal; Adult; Apgar Score; Birth Weight; Double-Blind Method; Female; Humans; | 2015 |
Prevention of preterm delivery with vaginal progesterone in women with preterm labour (4P): randomised double-blind placebo-controlled trial.
Topics: Administration, Intravaginal; Adult; Apgar Score; Birth Weight; Double-Blind Method; Female; Humans; | 2015 |
Tocolysis in women with advanced preterm labor: a secondary analysis of a randomized clinical trial.
Topics: Administration, Intravenous; Administration, Oral; Administration, Rectal; Adolescent; Adult; Female | 2016 |
Lipoxygenase and cyclooxygenase inhibitors reveal a complementary role of arachidonic acid derivatives in pregnant human myometrium.
Topics: Adult; Benzoquinones; Biopsy; Blotting, Western; Cyclooxygenase Inhibitors; Female; Flavanones; Huma | 2010 |
A randomized, double-masked trial of prophylactic indomethacin tocolysis versus placebo in women with premature rupture of membranes.
Topics: Adult; Double-Blind Method; Early Termination of Clinical Trials; Female; Fetal Membranes, Premature | 2011 |
Comparison of the efficacy and adverse effects of nifedipine and indomethacin for the treatment of preterm labor.
Topics: Adult; Drug Administration Schedule; Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Prem | 2011 |
Postoperative analgesia with tramadol and indomethacin for diagnostic curettage and early termination of pregnancy.
Topics: Abortion, Induced; Adult; Analgesics, Opioid; Anesthesia, General; Anti-Inflammatory Agents, Non-Ste | 2011 |
Comparison of diclofenac sodium with indomethacin suppositories for mediolateral episiotomies.
Topics: Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Episiotomy; Female; Humans; I | 2012 |
Effect of antenatal tocolysis on neonatal outcomes.
Topics: Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Magnesium | 2012 |
A prospective randomized safety trial of celecoxib for treatment of preterm labor.
Topics: Adolescent; Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Indome | 2002 |
A double-blind randomized study of fetal side effects during and after the short-term maternal administration of indomethacin, sulindac, and nimesulide for the treatment of preterm labor.
Topics: Adult; Amniotic Fluid; Diuresis; Double-Blind Method; Drug Administration Schedule; Ductus Arteriosu | 2003 |
Cervical incompetence prevention randomized cerclage trial: emergency cerclage with bed rest versus bed rest alone.
Topics: Anti-Bacterial Agents; Bed Rest; Cerclage, Cervical; Emergencies; Female; Gestational Age; Humans; I | 2003 |
Cervical incompetence prevention randomized cerclage trial: emergency cerclage with bed rest versus bed rest alone.
Topics: Anti-Bacterial Agents; Bed Rest; Cerclage, Cervical; Emergencies; Female; Gestational Age; Humans; I | 2003 |
Cervical incompetence prevention randomized cerclage trial: emergency cerclage with bed rest versus bed rest alone.
Topics: Anti-Bacterial Agents; Bed Rest; Cerclage, Cervical; Emergencies; Female; Gestational Age; Humans; I | 2003 |
Cervical incompetence prevention randomized cerclage trial: emergency cerclage with bed rest versus bed rest alone.
Topics: Anti-Bacterial Agents; Bed Rest; Cerclage, Cervical; Emergencies; Female; Gestational Age; Humans; I | 2003 |
The effect of short-term indomethacin therapy on amniotic fluid volume.
Topics: Amniotic Fluid; Drug Administration Schedule; Female; Humans; Incidence; Indomethacin; Obstetric Lab | 2005 |
Efficacy of suppository analgesia in postabortion pain reduction.
Topics: Acetaminophen; Adolescent; Adult; Aftercare; Analgesia; Analgesics; Drug Administration Routes; Fema | 2006 |
Impact of ibuprofen administration on renal drug clearance in the first weeks of life.
Topics: Age Factors; Amikacin; Anti-Bacterial Agents; Aspirin; Betamethasone; Birth Weight; Cyclooxygenase I | 2006 |
Further study of the inhibition of premature labor by indomethacin. Part II double-blind study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Indomethacin; | 1984 |
Further study of the inhibition of premature labor by indomethacin. Part II double-blind study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Indomethacin; | 1984 |
Further study of the inhibition of premature labor by indomethacin. Part II double-blind study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Indomethacin; | 1984 |
Further study of the inhibition of premature labor by indomethacin. Part II double-blind study.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Gestational Age; Humans; Indomethacin; | 1984 |
Treatment of premature labor with indomethacin.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomethacin; Infant, Newborn; | 1980 |
Therapeutic value of indomethacin in threatened abortion.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Abortion, Missed; Abortion, Threatened; Clinical Trials as To | 1980 |
The inhibition of premature labor with indomethacin.
Topics: Dinoprost; Double-Blind Method; Drug Evaluation; Estradiol; Female; Fetal Blood; Fetal Death; Humans | 1980 |
The inhibition of premature labor with indomethacin.
Topics: Dinoprost; Double-Blind Method; Drug Evaluation; Estradiol; Female; Fetal Blood; Fetal Death; Humans | 1980 |
The inhibition of premature labor with indomethacin.
Topics: Dinoprost; Double-Blind Method; Drug Evaluation; Estradiol; Female; Fetal Blood; Fetal Death; Humans | 1980 |
The inhibition of premature labor with indomethacin.
Topics: Dinoprost; Double-Blind Method; Drug Evaluation; Estradiol; Female; Fetal Blood; Fetal Death; Humans | 1980 |
Tocolysis in advanced preterm labor: impact on neonatal outcome.
Topics: Cohort Studies; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Magnesiu | 1995 |
A comparison of magnesium sulfate and indomethacin to magnesium sulfate only for tocolysis in preterm labor with advanced cervical dilation.
Topics: Adult; Cervix Uteri; Dilatation, Pathologic; Drug Therapy, Combination; Female; Humans; Indomethacin | 1995 |
Fetal cardiac function and ductus arteriosus during indomethacin and sulindac therapy for threatened preterm labor: a randomized study.
Topics: Ductus Arteriosus; Echocardiography; Female; Fetal Heart; Humans; Indomethacin; Obstetric Labor, Pre | 1995 |
Effects of prenatal exposure to betamethasone and indomethacin on the glomerular filtration rate in the preterm infant.
Topics: Betamethasone; Birth Weight; Female; Gestational Age; Glomerular Filtration Rate; Humans; Indomethac | 1994 |
Antenatal steroids, delivery mode, and intraventricular hemorrhage in preterm infants.
Topics: Cerebral Hemorrhage; Cesarean Section; Female; Humans; Indomethacin; Infant, Low Birth Weight; Infan | 1995 |
Increased incidence of bronchopulmonary dysplasia after antenatal administration of indomethacin to prevent preterm labor.
Topics: Adult; Bronchopulmonary Dysplasia; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; | 1994 |
Randomized trial of oral indomethacin and terbutaline sulfate for the long-term suppression of preterm labor.
Topics: Adult; Chi-Square Distribution; Ductus Arteriosus; Female; Humans; Indomethacin; Obstetric Labor, Pr | 1993 |
Efficacy and safety of indomethacin compared with magnesium sulfate in the management of preterm labor: a randomized study.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Obstetric Labor, Premature; Pregnancy; Prosp | 1993 |
The hemodynamic effects of antenatal indomethacin and a beta-sympathomimetic agent on the fetus and the newborn: a randomized study.
Topics: Adult; Blood Flow Velocity; Ductus Arteriosus, Patent; Female; Fetal Diseases; Fetus; Gestational Ag | 1993 |
The effect of antenatal dexamethasone administration on the fetal and neonatal ductus arteriosus. A randomized double-blind study.
Topics: Adult; Dexamethasone; Double-Blind Method; Ductus Arteriosus, Patent; Female; Gestational Age; Human | 1993 |
The effects of indomethacin and terbutaline on human fetal umbilical artery velocimetry: a randomized, double-blind study.
Topics: Diastole; Female; Humans; Indomethacin; Laser-Doppler Flowmetry; Pregnancy; Systole; Terbutaline; Um | 1993 |
The effect of acetaminophen on prostacyclin production in pregnant women.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Adult; Cells, Cultured; Double-Blind Method; Endotheliu | 1993 |
Antenatal exposure to steroids and the additional prophylaxis effect of indomethacin to prevent intraventricular hemorrhage.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Embryonic and Fetal Development; Femal | 1996 |
Rectal indomethacin potentiates spinal morphine analgesia after caesarean delivery.
Topics: Adjuvants, Anesthesia; Adult; Analgesia, Epidural; Analgesics, Opioid; Anesthesia, Obstetrical; Cesa | 1995 |
Growth and development until 18 months of children exposed to tocolytics indomethacin or nylidrin.
Topics: Child Development; Female; Follow-Up Studies; Growth; Humans; Indomethacin; Infant, Newborn; Infant, | 1996 |
Antecedents of cerebral palsy in a multicenter trial of indomethacin for intraventricular hemorrhage.
Topics: Cerebral Hemorrhage; Cerebral Palsy; Cerebral Ventricles; Chorioamnionitis; Female; Gestational Age; | 1997 |
Lack of effect of antenatal indomethacin on fetal cerebral blood flow.
Topics: Adolescent; Adult; Brain; Cerebral Hemorrhage; Female; Fetus; Humans; Incidence; Indomethacin; Infus | 1997 |
A placebo-controlled randomized trial of the terbutaline pump for prevention of preterm delivery.
Topics: Administration, Oral; Adrenergic beta-Agonists; Adult; Cervix Uteri; Drug Combinations; Female; Gest | 1997 |
The effect of indomethacin tocolysis in preterm labour on perinatal outcome: a randomised placebo-controlled trial.
Topics: Adult; Double-Blind Method; Female; Gestational Age; Humans; Indomethacin; Infant Mortality; Infant, | 1999 |
Outcome of children in the indomethacin intraventricular hemorrhage prevention trial.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Brain Damage, Chronic; Cerebral Hemorrhage; Cerebral Ventri | 2000 |
Indomethacin for preterm labor: a randomized comparison of vaginal and rectal-oral routes.
Topics: Administration, Intravaginal; Administration, Oral; Administration, Rectal; Adult; Female; Humans; I | 2000 |
Indomethacin and corticosteroids: an additive constrictive effect on the fetal ductus arteriosus.
Topics: Adrenal Cortex Hormones; Analysis of Variance; Blood Flow Velocity; Child, Preschool; Constriction, | 1999 |
A retrospective study of the effect of postoperative indomethacin rectal suppositories on the need for narcotic analgesia in patients who had a cesarean delivery while they were under regional anesthesia.
Topics: Analgesia; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Female; Hum | 2001 |
[Additional tocolysis via inhibition of prostaglandin synthetase with indometacin (author's transl)].
Topics: Clinical Trials as Topic; Cyclooxygenase Inhibitors; Drug Evaluation; Female; Humans; Indomethacin; | 1978 |
[Endogenous prostaglandin F 2 alpha in human pregnancy and during parturition (author's transl)].
Topics: Amniotic Fluid; Female; Humans; Indomethacin; Labor, Obstetric; Pregnancy; Prostaglandins; Prostagla | 1979 |
On the use of blockers of prostaglandin synthesis in the control of labor.
Topics: Animals; Aspirin; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Indome | 1978 |
The patent ductus arteriosus.
Topics: Acute Kidney Injury; Animals; Clinical Trials as Topic; Ductus Arteriosus; Ductus Arteriosus, Patent | 1978 |
Premature labor and indomethacin.
Topics: Apgar Score; Clinical Trials as Topic; Drug Evaluation; Estriol; Female; Humans; Indomethacin; Infan | 1978 |
A study of indomethacin combined with ritodrine in threatened preterm labor.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Fetal Death | 1978 |
Indomethacin increases abortifacient effect of PGE2 in man.
Topics: Abortifacient Agents; Abortion, Induced; Adult; Drug Synergism; Female; Humans; Indomethacin; Infusi | 1979 |
Therapeutic effectiveness of paracetamol in rheumatoid arthritis.
Topics: Acetaminophen; Analysis of Variance; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Female; Humans | 1975 |
Prostaglandins and post-abortion luteolysis in early pregnancy.
Topics: Abortion, Induced; Corpus Luteum; Estradiol; Female; Humans; Indomethacin; Pregnancy; Pregnancy Trim | 1975 |
The effect of tocolytic agents (indomethacin and terbutaline) on fetal breathing and body movements: a prospective, randomized, double-blind, placebo-controlled clinical trial.
Topics: Double-Blind Method; Female; Fetal Movement; Fetus; Humans; Indomethacin; Placebos; Pregnancy; Prosp | 1992 |
Randomized comparative trial of indomethacin and sulindac for the treatment of refractory preterm labor.
Topics: Adult; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Sulindac; Tocolytic Agen | 1992 |
Combination antibiotics and indomethacin in idiopathic preterm labor: a randomized double-blind clinical trial.
Topics: Ampicillin; Bacterial Infections; Double-Blind Method; Drug Therapy, Combination; Female; Humans; In | 1991 |
Catechol-O-methyltransferase activity in red blood cells in threatened preterm labor; effect of indomethacin and nylidrin.
Topics: Adult; Catechol O-Methyltransferase; Double-Blind Method; Erythrocytes; Female; Humans; Indomethacin | 1991 |
A randomized double-dummy comparison between indomethacin and nylidrin in threatened preterm labor.
Topics: Adult; Double-Blind Method; Female; Humans; Indomethacin; Nylidrin; Obstetric Labor, Premature; Preg | 1991 |
The effects of indomethacin and a beta-sympathomimetic agent on the fetal ductus arteriosus during treatment of premature labor: a randomized double-blind study.
Topics: Blood Flow Velocity; Cardiac Output, Low; Delivery, Obstetric; Double-Blind Method; Ductus Arteriosu | 1991 |
Randomized comparative trial of indomethacin and ritodrine for the long-term treatment of preterm labor.
Topics: Amniotic Fluid; Diseases in Twins; Female; Fetal Diseases; Humans; Hypertension, Pulmonary; Indometh | 1991 |
Prenatal administration of indomethacin as a tocolytic agent: effect on neonatal renal function.
Topics: Adult; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Kidney; Kidney Function Tes | 1990 |
Efficacy and safety of indomethacin versus ritodrine in the management of preterm labor: a randomized study.
Topics: Adult; Amniotic Fluid; Female; Humans; Indomethacin; Infant Mortality; Infant, Newborn; Obstetric La | 1989 |
Effectiveness of indomethacin (indocid) suppositories as post-episiotomy analgesia.
Topics: Adolescent; Adult; Analgesia; Clinical Trials as Topic; Episiotomy; Female; Humans; Indomethacin; Pa | 1988 |
Inhibition of arachidonic acid metabolism in the perinatal period: pharmacology, clinical application, and potential adverse effects.
Topics: Administration, Oral; Arachidonic Acid; Arachidonic Acids; Aspirin; Clinical Trials as Topic; Cycloo | 1986 |
Effect of indomethacin on the injection-abortion interval of 15(S) 15 methyl PGF2 alpha-induced mid-trimester abortions--a randomized study.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Abortion, Therapeutic; Adolescent; Adult; | 1987 |
1138 other studies available for indomethacin and Pregnancy
| Article | Year |
|---|---|
Long-term indomethacin therapy after laser surgery for TTTS. Worth the effort?
Topics: Female; Fetofetal Transfusion; Fetoscopy; Humans; Indomethacin; Laser Therapy; Pregnancy | 2022 |
Efficacy of long-term indomethacin therapy in prolonging pregnancy after fetoscopic laser surgery for twin-to-twin transfusion syndrome: a collaborative cohort study.
Topics: Adult; Female; Fetofetal Transfusion; Fetoscopy; Gestational Age; Humans; Indomethacin; Laser Therap | 2022 |
Altered cardiolipin metabolism is associated with cardiac mitochondrial dysfunction in pulmonary vascular remodeled perinatal rat pups.
Topics: Animals; Animals, Newborn; Cardiolipins; Disease Models, Animal; Female; Hypoxia; Indomethacin; Mito | 2022 |
Reduction of Severe Intraventricular Hemorrhage in Preterm Infants: A Quality Improvement Project.
Topics: Betamethasone; Cerebral Hemorrhage; Child; Female; Humans; Indomethacin; Infant; Infant, Extremely P | 2022 |
Model for severe intracranial hemorrhage and role of early indomethacin in extreme preterm infants.
Topics: Bronchopulmonary Dysplasia; Child; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant; | 2022 |
Gestational purple grape juice consumption does not change fetal ductus arteriosus constriction in Wistar rats.
Topics: Animals; Constriction; Ductus Arteriosus; Female; Indomethacin; Pregnancy; Prostaglandins; Rats; Rat | 2022 |
Impact of quality improvement outreach education on the incidence of acute brain injury in transported neonates born premature.
Topics: Brain Injuries; Female; Gestational Age; Humans; Incidence; Indomethacin; Infant, Newborn; Pregnancy | 2022 |
Effectiveness and care of the combination of indocin and painless delivery to shorten the duration of labor.
Topics: Delivery, Obstetric; Female; Humans; Indomethacin; Labor, Obstetric; Pregnancy | 2022 |
Assessing the Potency of the Novel Tocolytics 2-APB, Glycyl-H-1152, and HC-067047 in Pregnant Human Myometrium.
Topics: Aminophylline; Female; Humans; Indomethacin; Infant, Newborn; Myometrium; Nifedipine; Pregnancy; Pre | 2023 |
Treatment of Severe Fetal Ebstein's Anomaly with Prenatal Nonsteroidal Anti-Inflammatory Therapy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ebstein Anomaly; Female; Fetal Diseases; Heart Defects, Con | 2022 |
Effects of prophylactic indomethacin on morbidity and mortality in infants <25 weeks' gestation: a protocol driven intention to treat analysis.
Topics: Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Incidence; Indomethacin; Infant, Newborn | 2022 |
Efficacy of ultrasound-indicated cerclage in twin pregnancies: a retrospective case-control study matched by cervical length.
Topics: Case-Control Studies; Cerclage, Cervical; Cervix Uteri; Female; Humans; Indomethacin; Infant, Newbor | 2023 |
Effects of a small-baby protocol on early and long-term outcomes in extremely preterm infants: A quality improvement study.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant; Infant, Extremely Premature; Infant, Newb | 2023 |
Prophylactic indomethacin, antenatal betamethasone, and the risk of intestinal perforation in infants <28 weeks' gestation.
Topics: Betamethasone; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant; Infant, Newborn; In | 2023 |
TXA2 mediates LPA1-stimulated uterine contraction in late pregnant mouse.
Topics: Animals; Female; Indomethacin; Lysophospholipids; Mice; Muscle Contraction; Pregnancy; Receptors, Ly | 2023 |
Antenatal Steroids, Prophylactic Indomethacin, and the Risk of Spontaneous Intestinal Perforation.
Topics: Adult; Birth Weight; Female; Gestational Age; Humans; Indomethacin; Infant; Infant, Newborn; Intesti | 2023 |
Indomethacin Prophylaxis Is Associated with Reduced Risk of Intraventricular Hemorrhage in Extremely Preterm Infants Born in the Context of Amniotic Infection Syndrome.
Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant; Infant, Extrem | 2023 |
Vitamin C supplementation modulates crude oil contaminated water induced gravid uterine impaired contractile mechanism and foetal outcomes in Wistar rats.
Topics: Acetylcholine; Animals; Ascorbic Acid; Biomarkers; Dietary Supplements; Estrogens; Female; Humans; I | 2023 |
Response to Therapeutic Interventions in the NICU: Role of Sex as a Biological Variable.
Topics: Female; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; | 2023 |
The relationship between antenatal indomethacin as a tocolytic drug and neonatal outcomes: a retrospective cohort study.
Topics: Cohort Studies; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant; Infant, Newborn; In | 2021 |
Prostaglandin-E2 deficiency during late pregnancy and the associated increase in interleukin-1β derived from periaortic lymph nodes lead to abortion.
Topics: Abortion, Spontaneous; Animals; C-Reactive Protein; Chorionic Villi; Dinoprostone; Extracellular Mat | 2019 |
Early pregnancy loss in 15-hydroxyprostaglandin dehydrogenase knockout (15-HPGD
Topics: Abortion, Spontaneous; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprost; Dinoprostone; Embryo | 2019 |
Role of dopamine and selective dopamine receptor agonists on mouse ductus arteriosus tone and responsiveness.
Topics: Animals; Dopamine; Dopamine Agonists; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fenoldop | 2020 |
Maternal low body mass index is a risk factor for fetal ductal constriction following indomethacin use among women undergoing fetal repair of spina bifida.
Topics: Adult; Body Mass Index; Cohort Studies; Constriction, Pathologic; Cyclooxygenase Inhibitors; Ductus | 2020 |
Perioperative Use of Cefazolin and Indomethacin for Physical Examination-Indicated Cerclages to Improve Gestational Latency.
Topics: Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibiotic Prophylaxis; Cefaz | 2020 |
Effects and side effects of maternal administration of indomethacin for fetal tricuspid valve dysplasia.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Gestational Age; Heart Defects, Congenital; | 2021 |
Outcomes in infants < 29 weeks of gestation following single-dose prophylactic indomethacin.
Topics: Ductus Arteriosus, Patent; Female; Gestational Age; Humans; Indomethacin; Infant; Infant, Newborn; I | 2021 |
Effect of In Utero Non-Steroidal Anti-Inflammatory Drug Therapy for Severe Ebstein Anomaly or Tricuspid Valve Dysplasia (NSAID Therapy for Fetal Ebstein anomaly).
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Ductus Arteriosus; Duration of Therapy; Ebste | 2021 |
Effect of Beta 3 Adrenoreceptor Modulation on Patency of the Ductus Arteriosus.
Topics: Adrenergic beta-3 Receptor Antagonists; Animals; Animals, Newborn; Disease Models, Animal; Disease P | 2020 |
The effect of antenatal indomethacin on extremely preterm neonatal kidney function.
Topics: Acute Kidney Injury; Adult; Cohort Studies; Creatinine; Female; Humans; Indomethacin; Infant; Infant | 2022 |
Antenatal Risk Factors Associated with Spontaneous Intestinal Perforation in Preterm Infants Receiving Postnatal Indomethacin.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Case-Control Studi | 2021 |
The Effect of a Short Course of Tocolytic Indomethacin on Urinary Biomarkers in Premature Infants.
Topics: Acute Kidney Injury; Biomarkers; Creatinine; Cystatin C; Dopamine; Epidermal Growth Factor; Female; | 2022 |
Gestational Age-Dependent Variations in Effects of Prophylactic Indomethacin on Brain Injury and Intestinal Injury.
Topics: Brain Injuries; Canada; Female; Gestational Age; Humans; Indomethacin; Infant; Infant, Extremely Pre | 2021 |
Association of Co-Exposure of Antenatal Steroid and Prophylactic Indomethacin with Spontaneous Intestinal Perforation.
Topics: Brain Injuries; Canada; Female; Gestational Age; Humans; Indomethacin; Infant; Infant, Newborn; Infa | 2021 |
Cerclage in twin gestations: the need to consider the effect of antibiotics and indomethacin.
Topics: Anti-Bacterial Agents; Cerclage, Cervical; Female; Humans; Indomethacin; Pregnancy; Uterine Cervical | 2021 |
Antenatal Indomethacin Use Altering the Initial Presentation of Type 4A Bartter Syndrome.
Topics: Bartter Syndrome; Female; Hearing Loss, Sensorineural; Humans; Indomethacin; Pregnancy; Prenatal Dia | 2021 |
Prediction of maternal and fetal pharmacokinetics of indomethacin in pregnancy.
Topics: Female; Fetus; Humans; Indomethacin; Infant, Newborn; Models, Biological; Pregnancy; Pregnancy Trime | 2022 |
Cyclooxygenase-dependent mechanisms mediate in part the anti-dilatory effects of perivascular adipose tissue in uterine arteries from pregnant rats.
Topics: Acetylcholine; Adipose Tissue; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitor | 2021 |
The impact of indomethacin on the number of oocytes retrieved and IVF outcomes in patients with poor ovarian response.
Topics: Adult; Case-Control Studies; Female; Fertilization in Vitro; Gonadotropin-Releasing Hormone; Humans; | 2021 |
Inadvertent irreversible closure of arterial duct following therapeutic use of transplacental indomethacin in a fetus with severe Ebstein's anomaly and circular shunt.
Topics: Administration, Oral; Administration, Rectal; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteri | 2021 |
Sonographic detection of an infected maternal urachal cyst during pregnancy.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; | 2018 |
Effects of antenatal indomethacin on ductus arteriosus early closure and on adverse outcomes in preterm neonates.
Topics: Ductus Arteriosus; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Pregnancy; Retr | 2020 |
Indomethacin Dosing and Constriction of the Ductus Arteriosus During Open Fetal Surgery for Myelomeningocele Repair.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction; Dose-Response Relationship, Drug; Ductus Arte | 2019 |
Treatment of fetal circular shunt with non-steroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Ebstein Anomaly; Female; Gestati | 2019 |
Effect of betamethasone, indomethacin and fenoterol on neonatal and maternal mononuclear cells stimulated with Escherichia coli.
Topics: Adult; Anti-Inflammatory Agents; Betamethasone; Cytokines; Escherichia coli; Female; Fenoterol; Huma | 2019 |
Does Postmenstrual Age Affect Medical Patent Ductus Arteriosus Treatment Success in Preterm Infants?
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; | 2019 |
The Use of Indomethacin with Complete Amniotic Fluid Replacement and Classic Hysterotomy for the Reduction of Perinatal Complications of Intrauterine Myelomeningocele Repair.
Topics: Adolescent; Adult; Amniotic Fluid; Anti-Inflammatory Agents, Non-Steroidal; Female; Fetal Therapies; | 2019 |
Roles of organic anion transporter 2 and equilibrative nucleoside transporter 1 in hepatic disposition and antiviral activity of entecavir during non-pregnancy and pregnancy.
Topics: Animals; Antiviral Agents; Cell Proliferation; Cells, Cultured; Dogs; Dose-Response Relationship, Dr | 2019 |
Larger Dose Reductions of Vancomycin Required in Neonates with Patent Ductus Arteriosus Receiving Indomethacin versus Ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Ibuprofen | 2019 |
Cervical cerclage in twin pregnancies.
Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cerclage, Cervical; Cervix Uteri; Female; Feta | 2013 |
Patent ductus arteriosus treatment in preterm infants-time to consider shunt volume?
Topics: Ductus Arteriosus, Patent; Female; Hospital Mortality; Humans; Indomethacin; Infant, Very Low Birth | 2013 |
Reply to McNamara and Jain.
Topics: Ductus Arteriosus, Patent; Female; Hospital Mortality; Humans; Indomethacin; Infant, Very Low Birth | 2013 |
A liquid chromatography method with single quadrupole mass spectrometry for quantitative determination of indomethacin in maternal plasma and urine of pregnant patients.
Topics: Chromatography, Liquid; Female; Humans; Indomethacin; Mass Spectrometry; Pregnancy; Reference Standa | 2013 |
Tocolytic indomethacin: effects on neonatal haemodynamics and cerebral autoregulation in the preterm newborn.
Topics: Brain; Case-Control Studies; Cerebrovascular Circulation; Female; Gestational Age; Hemodynamics; Hom | 2013 |
Prostaglandins, masculinization and its disorders: effects of fetal exposure of the rat to the cyclooxygenase inhibitor- indomethacin.
Topics: Animals; Cryptorchidism; Cyclooxygenase Inhibitors; Dinoprostone; Female; Fetal Development; Humans; | 2013 |
Hemodynamic assessment of indomethacin-induced fetal heart failure in high-output state.
Topics: Adult; Female; Heart Failure; Hemangioma; Hemodynamics; Humans; Hydrops Fetalis; Indomethacin; Infan | 2013 |
Paracetamol, aspirin, and indomethacin induce endocrine disturbances in the human fetal testis capable of interfering with testicular descent.
Topics: Abnormalities, Drug-Induced; Abortion, Induced; Acetaminophen; Analgesics, Non-Narcotic; Androgens; | 2013 |
Relaxant effect of proton pump inhibitors on in vitro myometrium from pregnant women.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Apamin; Calcium; Dinoprostone; Esomeprazole; Female; Humans | 2014 |
Effect of NSAIDs and diuretics on nephrogenesis in an ex vivo embryogenic kidney model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Bone Morphogenetic Protein 7; Diuretics; Female; F | 2013 |
Maternal obesity impairs specific regulatory pathways in human myometrial arteries.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arteries; Biopsy; Body Mass Index; Body Weight; Endothelium | 2014 |
Fetal exposure to nonsteroidal anti-inflammatory drugs and spontaneous abortions.
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 | 2014 |
A prostaglandin E2 receptor antagonist prevents pregnancies during a preclinical contraceptive trial with female macaques.
Topics: Animals; Contraception; Contraceptive Agents; Female; Gene Expression Regulation; Indomethacin; Maca | 2014 |
Antenatal Bartter syndrome.
Topics: Bartter Syndrome; Chlorides; Fatal Outcome; Female; Humans; Hypokalemia; Hyponatremia; Indomethacin; | 2014 |
Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cefazolin; Cerclage, Cervical; Femal | 2014 |
In Reply: Dr. Burwick.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cefazolin; Cerclage, Cervical; Femal | 2014 |
Indomethacin administered early in the postnatal period results in reduced glomerular number in the adult rat.
Topics: Animals; Animals, Newborn; Body Weight; Cyclooxygenase Inhibitors; Female; Ibuprofen; Indomethacin; | 2014 |
Flow patterns in the ductus arteriosus during open fetal myelomeningocele repair.
Topics: Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anti-Inflammatory Agents, Non- | 2015 |
Liposomes: a nanoscale drug carrying system to prevent indomethacin passage to the fetus in a pregnant mouse model.
Topics: Administration, Oral; Animals; Biomarkers; Dinoprostone; Female; Indomethacin; Injections, Intraveno | 2015 |
NSAIDs and spontaneous abortions - true effect or an indication bias?
Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Femal | 2015 |
A prospective study of maternal preference for indomethacin prophylaxis versus symptomatic treatment of a patent ductus arteriosus in preterm infants.
Topics: Cardiovascular Agents; Decision Support Techniques; Ductus Arteriosus, Patent; Female; Humans; Indom | 2015 |
Differing In Vitro Potencies of Tocolytics and Progesterone in Myometrium From Singleton and Twin Pregnancies.
Topics: Female; Humans; Indomethacin; Myometrium; Oxytocin; Pregnancy; Pregnancy, Twin; Progesterone; Tocoly | 2016 |
Effects of Advancing Gestation and Non-Caucasian Race on Ductus Arteriosus Gene Expression.
Topics: Aorta; DNA; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Gene Expression Regulation, Develo | 2015 |
Reply: To PMID 25448524.
Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Intracranial Hemorrhages; Leukomalacia, Pe | 2015 |
Indomethacin as a tocolytic harmful to preterm infant.
Topics: Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Intracranial Hemorrhages; Leukomalacia, Pe | 2015 |
Role of ABCB1, ABCG2, ABCC2 and ABCC5 transporters in placental passage of zidovudine.
Topics: Acridines; Animals; Anti-HIV Agents; ATP-Binding Cassette Transporters; Dogs; Drug Interactions; Fem | 2016 |
Development of Physiologically Based Pharmacokinetic/Pharmacodynamic Model for Indomethacin Disposition in Pregnancy.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Indomethacin; Models, Biological; Pregnancy | 2015 |
Effect of obesity on neonatal outcomes in pregnancies with preterm premature rupture of membranes.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Birth Weight; Case-Control Studies; Cerebral Hemorrhage; | 2016 |
Indomethacin for treatment of prolapsed amniotic sac "hourglass membranes" presented at late mid-trimester.
Topics: Adult; Amnion; Female; Humans; Indomethacin; Pregnancy; Pregnancy Complications; Pregnancy Trimester | 2016 |
Progesterone suppressed vasoconstriction in human umbilical vein via reducing calcium entry.
Topics: Biological Transport; Calcium; Calcium Channels, L-Type; Dose-Response Relationship, Drug; Endotheli | 2016 |
Perinatal Outcomes after Short versus Prolonged Indomethacin for Tocolysis in Women with Preterm Labor.
Topics: Adult; Drug Administration Schedule; Enterocolitis, Necrotizing; Female; Gestational Age; Humans; In | 2016 |
Editorial: Patent Ductus Arteriosus in Extremely Premature Neonates.
Topics: Anterior Cerebral Artery; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Echocardiography, Do | 2016 |
Drug delivery to the human and mouse uterus using immunoliposomes targeted to the oxytocin receptor.
Topics: Albuterol; Animals; Drug Delivery Systems; Female; Indomethacin; Liposomes; Mice; Myometrium; Nifedi | 2017 |
Uterus-targeted liposomes for preterm labor management: studies in pregnant mice.
Topics: Animals; Disease Models, Animal; Drug Compounding; Female; Gene Expression; Hormone Antagonists; Hum | 2016 |
Outcomes With Cerclage Alone Compared With Cerclage Plus 17α-Hydroxyprogesterone Caproate.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adult; Cerclage, Cervical; Cohort Studies; Female; Humans; Hy | 2016 |
Successful management of intraoperative haemorrhage during emergency cervical cerclage using balloon tamponade.
Topics: Adult; Balloon Occlusion; Blood Loss, Surgical; Cerclage, Cervical; Extraembryonic Membranes; Female | 2017 |
Evaluation of the effect of indomethacin and piroxicam administration before embryo transfer on pregnancy rate.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Embryo Implantation; Embryo Transfer; Female; Fertil | 2017 |
Dual effect of anandamide on rat placenta nitric oxide synthesis.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Modulators; Endocannabinoids; Female; Indomethacin; | 2008 |
Sevoflurane and the feto-placental vasculature: the role of nitric oxide and vasoactive eicosanoids.
Topics: Anesthetics, Inhalation; Dose-Response Relationship, Drug; Eicosanoids; Female; Fetus; Humans; In Vi | 2008 |
Chorioamnionitis and ontogeny of circulating prostaglandin and thromboxane in preterm infants.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; Bronchopulmonary Dysplasia | 2008 |
Investigating the potential role of multi-drug resistance protein (MRP) transporters in fetal to maternal glyburide efflux in the human placenta.
Topics: Adult; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Indomethacin; Male; Ma | 2008 |
Does indomethacin prevent preterm birth in women with cervical dilatation in the second trimester?
Topics: Adult; Amniocentesis; Anti-Bacterial Agents; Birth Weight; Cerclage, Cervical; Cohort Studies; Deliv | 2009 |
Regulation of the fetal mouse ductus arteriosus is dependent on interaction of nitric oxide and COX enzymes in the ductal wall.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Cyclooxygenase Inhibito | 2009 |
Prenatal administration of indomethacin modulates Th2 cytokines in juvenile rats.
Topics: Animals; Cytokines; Dose-Response Relationship, Drug; Female; Fetus; Indomethacin; Interferon-gamma; | 2009 |
Pregnancy outcome after placement of 'rescue' Shirodkar cerclage.
Topics: Adolescent; Adult; Bed Rest; Cerclage, Cervical; Cohort Studies; Combined Modality Therapy; Female; | 2009 |
Delayed neonatal closure of the ductus arteriosus following early in utero exposure to indomethacin in the rat.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibito | 2009 |
Indomethacin, ibuprofen and gentamicin administered during late stages of glomerulogenesis do not reduce glomerular number at 14 days of age in the neonatal rat.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Body Weight; Cardiovascu | 2009 |
Collaborative work on evaluation of ovarian toxicity. 12) Effects of 2- or 4-week repeated dose studies and fertility study of indomethacin in female rats.
Topics: Animals; Cyclooxygenase Inhibitors; Drug Administration Schedule; Estrous Cycle; Female; Fertility; | 2009 |
Fetal reversed constrictive effect of indomethacin and postnatal delayed closure of the ductus arteriosus following administration of transplacental magnesium sulfate in rats.
Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Drug Ant | 2009 |
Indomethacin-induced colon perforation in Bartter's syndrome.
Topics: Adult; Amniotic Fluid; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Colonic Diseases; | 2009 |
Term life birth after late abortion of the first twin.
Topics: Abortion, Spontaneous; Adult; Antibiotic Prophylaxis; Clinical Protocols; Female; Gestational Age; H | 2009 |
Resistance artery adaptation to pregnancy counteracts the vasoconstricting influence of plasma from normal pregnant women.
Topics: Adaptation, Physiological; Adult; Analysis of Variance; Angiography; Animals; Blood Pressure; Blood | 2010 |
In vivo dilatation of the ductus arteriosus induced by furosemide in the rat.
Topics: Animals; Animals, Newborn; Cesarean Section; Cyclooxygenase Inhibitors; Dilatation, Pathologic; Dise | 2010 |
Reversible ductus arteriosus constriction due to maternal indomethacin after fetal intervention for hypoplastic left heart syndrome with intact/restrictive atrial septum.
Topics: Atrial Septum; Catheterization; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Therapies | 2010 |
Cytomegalovirus-associated acute hydramnios treated by amniocentesis and maternal indomethacin.
Topics: Amniocentesis; Amniotic Fluid; Cytomegalovirus Infections; Female; Humans; Indomethacin; Infant, New | 2009 |
Failure of postnatal ductus arteriosus closure in prostaglandin transporter-deficient mice.
Topics: Animals; Cardiovascular Agents; Cells, Cultured; Dinoprostone; Disease Models, Animal; Ductus Arteri | 2010 |
Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury.
Topics: Acetaminophen; Adrenal Cortex Hormones; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Ste | 2010 |
B-type natriuretic peptide predicts responses to indomethacin in premature neonates with patent ductus arteriosus.
Topics: Cardiovascular Agents; Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Gestational Age | 2010 |
Indomethacin as a diagnostic and therapeutic tool in the management of progressive cervical shortening diagnosed by trans-vaginal sonography.
Topics: Cerclage, Cervical; Cervical Length Measurement; Female; Humans; Indomethacin; Obstetric Labor, Prem | 2011 |
Prenatal or postnatal indomethacin exposure and neonatal gut injury associated with isolated intestinal perforation and necrotizing enterocolitis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cerebral Hemorrhage; Cerebral Ventricles; Drug Administrati | 2010 |
Regulation of progesterone receptor A and B expression in human preterm, term, and postterm placental villi.
Topics: Adult; Blotting, Western; China; Chorionic Villi; Chorionic Villi Sampling; Cohort Studies; Female; | 2010 |
Antenatal Bartter syndrome: analysis of two cases with placental findings.
Topics: Adult; Amniocentesis; Amniotic Fluid; Anti-Inflammatory Agents, Non-Steroidal; Arteriosclerosis; Bar | 2010 |
Antenatal magnesium sulfate and the postnatal response of the ductus arteriosus to indomethacin in extremely preterm neonates.
Topics: Drug Administration Schedule; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Gestational Age; | 2011 |
Mesenchymal stromal cells use PGE2 to modulate activation and proliferation of lymphocyte subsets: Combined comparison of adipose tissue, Wharton's Jelly and bone marrow sources.
Topics: Adipose Tissue; Adolescent; Adult; Antigens, CD; Bone Marrow; Cell Proliferation; Cells, Cultured; C | 2010 |
Effect of maternal body mass index on in vitro response to tocolytics in term myometrium.
Topics: Adult; Area Under Curve; Biopsy; Body Mass Index; Female; Humans; In Vitro Techniques; Indomethacin; | 2010 |
[Indometacin: come back of a controversial tocolytic? Obstetrical point of view].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Female; Humans; Indomethacin; | 2010 |
Augmented EDHF signaling in rat uteroplacental vasculature during late pregnancy.
Topics: Animals; Apamin; Biological Factors; Calcium Signaling; Charybdotoxin; Cyclooxygenase Inhibitors; Fe | 2010 |
Nifedipine for the treatment of preterm labor in twin and singleton pregnancies.
Topics: Adult; Databases, Factual; Female; Gestational Age; Hospitals, University; Humans; Indomethacin; Inf | 2011 |
Indomethacin tocolysis and neurodevelopmental outcome.
Topics: Adult; Child, Preschool; Cohort Studies; Developmental Disabilities; Female; Humans; Indomethacin; M | 2011 |
Successful management of a high-risk pregnancy with polyhydramnios, IUGR and recurrent pregnancy loss in a chronic renal failure patient: a case report.
Topics: Abortion, Habitual; Adult; Amniotic Fluid; Betamethasone; Birth Weight; Female; Fetal Growth Retarda | 2011 |
Antenatal Bartter syndrome: a rare cause of unexplained severe polyhydramnios.
Topics: Adult; Amniotic Fluid; Bartter Syndrome; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Pr | 2011 |
The risk of necrotizing enterocolitis after indomethacin tocolysis.
Topics: Cohort Studies; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infant, P | 2011 |
Impact of early malnourishment on the chronic inflammatory response and its implications for the effect of indomethacin on Wistar rats.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bioethics; C-Reactive Protein; Female | 2011 |
Indomethacin in pregnancy: applications and safety.
Topics: Cerclage, Cervical; Cerebral Hemorrhage; Ductus Arteriosus; Enterocolitis, Necrotizing; Female; Fetu | 2012 |
What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants?
Topics: Cardiac Surgical Procedures; Cohort Studies; Combined Modality Therapy; Cyclooxygenase Inhibitors; D | 2012 |
Inhibition of epoxy-eicosanoid degradation improves the tocolytic effects of indomethacin in the uterus from pregnant women.
Topics: Adamantane; Adult; Amides; Arachidonic Acid; Cesarean Section; Cyclooxygenase 2; Cyclooxygenase Inhi | 2011 |
Inhibition of uterine contractility with various tocolytics with and without progesterone: in vitro studies.
Topics: Adult; Female; Humans; Indomethacin; Magnesium Sulfate; Myometrium; Nifedipine; Obstetric Labor, Pre | 2012 |
Early undernutrition is associated with attenuated inflammatory response and alteration in pharmacological efficacy of indomethacin in rats.
Topics: Analysis of Variance; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Birth Weight; C | 2012 |
Patent ductus arteriosus: mechanisms and management.
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Echocardiography; Female; History, 16th Century; H | 2012 |
Does treatment of patent ductus arteriosus with cyclooxygenase inhibitors affect neonatal regional tissue oxygenation?
Topics: Analysis of Variance; Blood Gas Analysis; Cerebrovascular Circulation; Chi-Square Distribution; Chro | 2012 |
[Treatment of preterm delivery--therapeutic algorithm].
Topics: Ambroxol; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Expectorants; Female; G | 2011 |
Paracetamol (acetaminophen), aspirin (acetylsalicylic acid) and indomethacin are anti-androgenic in the rat foetal testis.
Topics: Acetaminophen; Androgen Antagonists; Animals; Arachidonic Acid; Aspirin; Cryptorchidism; Endocrine D | 2012 |
Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms.
Topics: Adult; Arteries; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans | 2012 |
Impact of maternal dexamethasone on coronary PGE(2) production and prostaglandin-dependent coronary reactivity.
Topics: Angiotensin II; Animals; Cells, Cultured; Coronary Vessels; Cyclooxygenase Inhibitors; Dexamethasone | 2012 |
Protective effects of indomethacin and dexamethasone in a goat model with intrauterine balloon aortic valvuloplasty.
Topics: Animals; Aortic Valve Stenosis; Balloon Valvuloplasty; Dexamethasone; Female; Goats; Indomethacin; M | 2012 |
Maternal azithromycin therapy for Ureaplasma intraamniotic infection delays preterm delivery and reduces fetal lung injury in a primate model.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2012 |
Increased cyclooxygenase-2-derived prostanoids contributes to the hyperreactivity to noradrenaline in mesenteric resistance arteries from offspring of diabetic rats.
Topics: Animals; Cells, Cultured; Cyclooxygenase 2; Diabetes Mellitus, Experimental; Dinoprost; Endothelial | 2012 |
Deleterious effects of indomethacin in the mid-gestation human intestine.
Topics: Aborted Fetus; Anti-Inflammatory Agents; Female; Humans; Indomethacin; Intestinal Mucosa; Intestines | 2013 |
Endothelial function is preserved in pregnant women with well-controlled type 1 diabetes.
Topics: Adult; Analysis of Variance; Arteries; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Endothe | 2002 |
The role of gap junctions in mediating endothelium-dependent responses to bradykinin in myometrial small arteries isolated from pregnant women.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Biological Factors; Br | 2002 |
In vitro study of tocolytic effect of rofecoxib, a specific cyclo-oxygenase 2 inhibitor. Comparison and combination with other tocolytic agents.
Topics: Analysis of Variance; Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cycl | 2002 |
The effect of in utero exposure to indomethacin on the need for surgical closure of a patent ductus arteriosus in the neonate.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus, Patent; Female; Humans; Indometha | 2002 |
Interval delivery and aggressive tocolysis in high-order multiple gestation. A report of three cases.
Topics: Adult; Delivery, Obstetric; Female; Head-Down Tilt; Humans; Indomethacin; Infant, Newborn; Magnesium | 2002 |
Abnormalities in intracellular Ca2+ regulation in fetal vascular smooth muscle in pre-eclampsia: enhanced sensitivity to arachidonic acid.
Topics: Arachidonic Acid; Calcium; Cyclooxygenase Inhibitors; Female; Fetus; Humans; Indomethacin; Lipoxygen | 2003 |
Embryonal mass and hormone-associated effects of pregnancy inducing a differential growth of four murine tumors.
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Division; Estrogens; Female; | 2002 |
Inhibition of in vivo constriction of fetal ductus arteriosus by endothelin receptor blockade in rats.
Topics: Animals; Antihypertensive Agents; Bosentan; Cardiovascular Agents; Dexamethasone; Dioxoles; Drug Int | 2003 |
Pregnancy influence on the vascular interactions between nitric oxide and other endothelium-derived mediators in rat kidney.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2003 |
Are localized intestinal perforations distinct from necrotizing enterocolitis?
Topics: Adult; Catheterization; Dexamethasone; Diagnosis, Differential; Enterocolitis, Necrotizing; Female; | 2003 |
The youngest children are too frequently subject to drug errors, study says.
Topics: Anti-Infective Agents; Antibodies, Monoclonal; Antiviral Agents; Child, Preschool; Cisapride; Female | 2002 |
Effect of indomethacin on amniotic fluid prostaglandin and aldosterone levels in a fetus with Bartter syndrome.
Topics: Adult; Aldosterone; Amniotic Fluid; Bartter Syndrome; Cesarean Section; Female; Fetal Diseases; Huma | 2003 |
Effects of endotoxin and macrophage-related cytokines on the contractile activity of the gravid murine uterus.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cytokines; Endotoxins; Female; In Vitro Techniques | 2003 |
Effects of prostaglandins E2 and F2alpha (PGE2; PGF2alpha), trilostane, mifepristone, palmitic acid (PA), indomethacin (INDO), ethamoxytriphetol (MER-25), PGE2 + PA, or PGF2alpha + PA on PGE2, PGF2alpha, and progesterone secretion by bovine corpora lutea
Topics: Abortifacient Agents, Steroidal; Animals; Cattle; Corpus Luteum; Dihydrotestosterone; Dinoprost; Din | 2002 |
The effects of non-steroidal anti-inflammatory compounds on human myometrial contractility.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cells, Cultured; Cyclooxygenase 1; Cyclooxygenase 2; Cycloo | 2003 |
Effect of selective vs. non-selective cyclo-oxygenase inhibitors on fetal membrane prostaglandin synthesis.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase 1; Cyclooxygenase 2; Cycloox | 2003 |
Therapeutic effect of cyclo-oxygenase inhibitors with different isoform selectivity in lipopolysaccharide-induced preterm birth in mice.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Femal | 2003 |
Angiotensin II type 1 receptor A1166C polymorphism and prophylactic indomethacin treatment induced ductus arteriosus closure in very low birth weight neonates.
Topics: Cardiovascular Agents; Ductus Arteriosus, Patent; Female; Genotype; Gestational Age; Humans; Indomet | 2003 |
Noradrenaline-induced vasoconstriction in the uterine vascular bed of pregnant rats chronically treated with L-NAME: role of prostanoids.
Topics: Animals; Blood Pressure; Drug Interactions; Enzyme Inhibitors; Female; Indomethacin; NG-Nitroarginin | 2003 |
Indomethacin responsiveness of patent ductus arteriosus and renal abnormalities in preterm infants treated with indomethacin.
Topics: Cardiovascular Agents; Chorioamnionitis; Ductus Arteriosus, Patent; Echocardiography, Doppler; Femal | 2003 |
RHEUMATOID ARTHRITIS AND PREGNANCY.
Topics: Arthritis; Arthritis, Rheumatoid; Chloroquine; Drug Therapy; Female; Gold; Humans; Hydrocortisone; I | 1965 |
Neonatal outcome after exposure to indomethacin in utero: a retrospective case cohort study.
Topics: Apgar Score; Betamethasone; Birth Weight; Cesarean Section; Cohort Studies; Female; Fetal Blood; Ges | 2003 |
Pharmacological knockout of endothelin ET(A) receptors.
Topics: Abnormalities, Drug-Induced; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal; Aor | 2003 |
Epidermal growth factor modulation of prostaglandins and nitrite biosynthesis in rat fetal membranes.
Topics: Animals; Cyclooxygenase Inhibitors; Epidermal Growth Factor; ErbB Receptors; Extraembryonic Membrane | 2004 |
Effects of dexamethasone and sulfasalazine on prostaglandin E2 output by human placental cells in vitro.
Topics: Animals; Cells, Cultured; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprost; Dinoprostone; Dose-Re | 2004 |
Comparison of nonselective cyclo-oxygenase (COX) inhibitor and selective COX-2 inhibitors on preimplantation loss, postimplantation loss and duration of gestation: an experimental study.
Topics: Animals; Celecoxib; Cyclooxygenase Inhibitors; Embryonic Development; Female; Gestational Age; Indom | 2004 |
The mechanism of EDHF-mediated responses in subcutaneous small arteries from healthy pregnant women.
Topics: Adolescent; Adult; Arteries; Biological Factors; Bradykinin; Cesarean Section; Cyclooxygenase Inhibi | 2004 |
Acute severe reversible oligohydramnios induced by indomethacin in a patient with rheumatoid arthritis: a case report and review of the literature.
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin | 2004 |
Persistent pulmonary hypertension in a premature newborn after 16 hours of antenatal indomethacin exposure.
Topics: Adult; Constriction, Pathologic; Diseases in Twins; Ductus Arteriosus; Female; Gestational Age; Huma | 2004 |
Effects of aminoguanidine and cyclooxygenase inhibitors on nitric oxide and prostaglandin production, and nitric oxide synthase and cyclooxygenase expression induced by lipopolysaccharide in the estrogenized rat uterus.
Topics: Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprost; Dinopr | 2004 |
[Prenatal Bartter's syndrome. Report of two cases].
Topics: Adult; Amniocentesis; Anti-Inflammatory Agents, Non-Steroidal; Bartter Syndrome; Chloride Channels; | 2003 |
Prostanoids contribute to the oxygen-dependent regulation of vascular tone of human umbilical vein.
Topics: Endothelium, Vascular; Female; Humans; Indomethacin; Membrane Potentials; Muscle Contraction; Muscle | 2004 |
Induction of PGE2 by estradiol mediates developmental masculinization of sex behavior.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Dinoprostone; Estradiol; Female; Indomethacin; | 2004 |
Endothelin-induced constriction of the ductus venosus in fetal sheep: developmental aspects and possible interaction with vasodilatory prostaglandin.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Canada; Dinoprostone; Dose-Response Relationship, Drug; Drug | 2004 |
Physiological involvement of placental endothelin-1 and prostaglandin F2alpha in uteroplacental circulatory disturbance in pregnant rats exposed to heat stress.
Topics: Animals; Body Temperature; Bosentan; Colon; Cyclooxygenase Inhibitors; Dinoprost; Endothelin Recepto | 2004 |
An EP4 receptor agonist prevents indomethacin-induced closure of rat ductus arteriosus in vivo.
Topics: Animals; Cardiovascular Agents; Drug Interactions; Ductus Arteriosus; Female; Fetal Diseases; Heptan | 2004 |
In situ inhibition of uterine activity by indomethacin: possible relevance to preterm labor prevention after fetal surgery.
Topics: Animals; Depression, Chemical; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Femal | 2004 |
Interactive effect of sevoflurane with isradipine or indomethacin on spontaneous contractile activity of isolated pregnant rat myometrium.
Topics: Anesthetics, Inhalation; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; | 2004 |
Prostaglandin E2--mediated relaxation of the ductus arteriosus: effects of gestational age on g protein-coupled receptor expression, signaling, and vasomotor control.
Topics: 16,16-Dimethylprostaglandin E2; 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Adenylyl Cyclases | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2004 |
Cyclooxygenase-2-derived endogenous prostacyclin enhances mouse embryo hatching.
Topics: Animals; Arachidonic Acid; Blastocyst; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2004 |
Prostaglandins are responsible for the inhibition of breathing observed with a placental extract in fetal sheep.
Topics: Animals; Enzyme Inhibitors; Female; Fetal Blood; Fetal Movement; Fetus; Indomethacin; Placenta; Preg | 2004 |
Is indomethacin harmful for fetus? How much?
Topics: Abnormalities, Drug-Induced; Confounding Factors, Epidemiologic; Female; Fetus; Humans; Indomethacin | 2004 |
Possible antenatal and perinatal related factors in development of cystic periventricular leukomalacia.
Topics: Apgar Score; Case-Control Studies; Causality; Cerebral Palsy; Chorioamnionitis; Comorbidity; Female; | 2005 |
Combining phenobarbital and indomethacin to improve early neonatal outcomes in the extremely low birth weight infant.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Drug Therapy, Combination; Enterocolitis, | 2005 |
[Therapy of chronic idiopathic hydramnios with indomethacin].
Topics: Chronic Disease; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Polyhydramnios; Pre | 2004 |
Effects of diabetes and insulin resistance in pregnant rats on ex vivo vascular reaction to magnesium.
Topics: Alloxan; Animals; Aorta; Blood Glucose; Diabetes Mellitus, Experimental; Female; In Vitro Techniques | 2004 |
Dysfunction of the cyclo-oxygenase pathway in the foetoplacental circulation in Type 1 diabetes mellitus.
Topics: Adult; Blood Pressure; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Female; Humans; In Vitr | 2005 |
Shortening increases spontaneous contractility in myometrium from pregnant women at term.
Topics: Analysis of Variance; Cesarean Section; Female; Humans; Indomethacin; Muscle Contraction; Myometrium | 2005 |
Outcome of very low birth weight infants exposed to antenatal indomethacin for tocolysis.
Topics: Cause of Death; Cohort Studies; Critical Care; Ductus Arteriosus, Patent; Enterocolitis, Necrotizing | 2005 |
Efficacy of aggressive tocolysis for preterm labor with advanced cervical dilatation.
Topics: Adrenal Cortex Hormones; Adult; Delivery, Obstetric; Female; Gestational Age; Humans; Indomethacin; | 2005 |
Regulation of Toxoplasma gondii multiplication in BeWo trophoblast cells: cross-regulation of nitric oxide production and polyamine biosynthesis.
Topics: Animals; Arginase; Cell Line; Cyclooxygenase 2 Inhibitors; Enzyme Inhibitors; Female; Fibroblasts; H | 2005 |
Indomethacin tocolysis and white matter injury in preterm infants.
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant; Infant, Newborn; Infant, Premature; Israe | 2005 |
In vivo dilatation of the fetal and postnatal ductus arteriosus by inhibition of phosphodiesterase 3 in rats.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Animals, Newborn; Cyclic Nucleotide Phosphodiesterases | 2006 |
The effects of prostaglandin F2alpha treatment on peripheral-type benzodiazepine receptors in the ovary and uterus during pseudopregnancy of rats.
Topics: Animals; Carrier Proteins; Corpus Luteum; Dinoprost; Female; Gonadotropins, Equine; Indomethacin; Is | 2006 |
Structural and functional comparison of mast cells in the pregnant versus nonpregnant human uterus.
Topics: Ambrosia; Antigens, Plant; Case-Control Studies; Cell Count; Cyclooxygenase Inhibitors; Diphenhydram | 2006 |
Kinetics and secretion of placental growth hormone around parturition.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Carrier Proteins; Cesarean Section; C | 2006 |
Thromboxane mediates neutrophil superoxide production in pregnancy.
Topics: Arachidonic Acid; Aspirin; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; H | 2006 |
Comparative effects of early postnatal ibuprofen and indomethacin on VEGF, IGF-I, and GH during rat ocular development.
Topics: Animals; Animals, Newborn; Cyclooxygenase Inhibitors; Eye; Female; Growth Hormone; Ibuprofen; Indome | 2006 |
[Study on regulatory effect of Bushen Antai Recipe on levels of estrogen and progesterone in blastocyst implantation dysfunction mice].
Topics: Animals; Drugs, Chinese Herbal; Embryo Implantation; Embryo Implantation, Delayed; Estrogens; Female | 2006 |
Vaginal versus oral indomethacin in a rabbit model for non-infection-mediated preterm birth: an alternate tocolytic approach.
Topics: Administration, Intravaginal; Administration, Oral; Animals; Cervix Uteri; Female; Indomethacin; Mat | 2006 |
New insights into spontaneous intestinal perforation using a national data set (3): antenatal steroids have no adverse association with spontaneous intestinal perforation.
Topics: Case-Control Studies; Drug Administration Schedule; Female; Humans; Incidence; Indomethacin; Infant; | 2006 |
The effects of indomethacin tocolysis on the postnatal response of the ductus arteriosus to indomethacin in extremely low birth weight infants.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Extremely Low Bi | 2007 |
Connexin 43 mediates endothelium-derived hyperpolarizing factor-induced vasodilatation in subcutaneous resistance arteries from healthy pregnant women.
Topics: Adult; Arteries; Biological Factors; Bradykinin; Connexin 43; Connexins; Cyclooxygenase Inhibitors; | 2007 |
Lenticulostriate vasculopathy in twin-to-twin transfusion syndrome.
Topics: Basal Ganglia Cerebrovascular Disease; Cardiovascular Agents; Continuous Positive Airway Pressure; D | 2006 |
Reduced nitric oxide synthase and cyclo-oxygenase activity in the uterus of non-obese diabetic mice.
Topics: Animals; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Dinoprostone; Enzyme Activation; Fema | 2006 |
Cyclooxygenase-2 mediates the sensitizing effects of systemic IL-1-beta on excitotoxic brain lesions in newborn mice.
Topics: Animals; Animals, Newborn; Brain; Cerebral Palsy; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dinop | 2007 |
Gastrointestinal perforation in very low-birthweight infants.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Diagnosis, Differential; Enterocolitis, Necrotizing; Female | 2006 |
Effect of prenatal administration of NSAIDs on the immune response in juvenile and adult rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibody Formation; Aspirin; Diclofenac; Enzyme-Li | 2007 |
The influence of interleukin-1beta on oxytocin signalling in primary cells of human decidua.
Topics: Arachidonic Acid; Base Sequence; Cells, Cultured; Decidua; Dinoprostone; DNA Primers; Female; Humans | 2007 |
The safety of prolonged indomethacin therapy.
Topics: Adolescent; Adult; Cohort Studies; Drug-Related Side Effects and Adverse Reactions; Ductus Arteriosu | 2007 |
The effects of caffeine on the preterm sheep ductus arteriosus.
Topics: Animals; Caffeine; Cardiovascular Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Dru | 2007 |
Renal glomeruli and tubular injury following indomethacin, ibuprofen, and gentamicin exposure in a neonatal rat model.
Topics: Analgesics, Non-Narcotic; Animals; Animals, Newborn; Anti-Bacterial Agents; Cardiovascular Agents; F | 2007 |
What regulates placental steroidogenesis in 90-day pregnant ewes?
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Estradiol; Female; Gene Expression Regulation, Develo | 2007 |
Natural cycle IVF with and without terminal HCG: learning from failed cycles.
Topics: Adult; Appointments and Schedules; Chorionic Gonadotropin; Cyclooxygenase Inhibitors; Embryo Transfe | 2007 |
A cost decision analysis of 4 tocolytic drugs.
Topics: Decision Trees; Drug Costs; Female; Humans; Indomethacin; Magnesium Sulfate; Nifedipine; Obstetric L | 2007 |
Advantages of mixed effects models over traditional ANOVA models in developmental studies: a worked example in a mouse model of fetal alcohol syndrome.
Topics: Analysis of Variance; Animals; Behavior, Animal; Bias; Body Weight; Brain; Disease Models, Animal; E | 2007 |
Immunomodulators plus antibiotics delay preterm delivery after experimental intraamniotic infection in a nonhuman primate model.
Topics: Amnion; Amniotic Fluid; Ampicillin; Animals; Anti-Bacterial Agents; Cesarean Section; Chorioamnionit | 2007 |
Risk factors for acute retinopathy of prematurity.
Topics: Birth Weight; Cerebral Hemorrhage; Female; Gestational Age; Humans; Incidence; Indomethacin; Infant, | 2007 |
Respiratory Deleted in Malignant Brain Tumours 1 (DMBT1) levels increase during lung maturation and infection.
Topics: Biomarkers; Blotting, Western; Calcium-Binding Proteins; Communicable Diseases; DNA-Binding Proteins | 2008 |
Endothelium-derived hyperpolarizing factor in preeclampsia: heterogeneous contribution, mechanisms, and morphological prerequisites.
Topics: Adolescent; Adult; Arachidonic Acid; Arteries; Biological Factors; Biopsy; Bradykinin; Cardiovascula | 2008 |
Indomethacin administration at the time of ultrasound-indicated cerclage: is there an association with a reduction in spontaneous preterm birth?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cerclage, Cervical; Cervical Length Measurement; Cer | 2008 |
Spontaneous ovulation rate before oocyte retrieval in modified natural cycle IVF with and without indomethacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fertilization in Vitro; Humans; Indomethacin | 2008 |
Spontaneous ovulation rate before oocyte retrieval in modified natural cycle IVF with and without indomethacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fertilization in Vitro; Humans; Indomethacin | 2008 |
Spontaneous ovulation rate before oocyte retrieval in modified natural cycle IVF with and without indomethacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fertilization in Vitro; Humans; Indomethacin | 2008 |
Spontaneous ovulation rate before oocyte retrieval in modified natural cycle IVF with and without indomethacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Female; Fertilization in Vitro; Humans; Indomethacin | 2008 |
Indomethacin promotes nitric oxide function in the ductus arteriosus in the mouse.
Topics: Administration, Oral; Animals; Carbon Monoxide; Cyclooxygenase Inhibitors; Dinoprostone; Drug Admini | 2008 |
Spontaneous closure of the patent ductus arteriosus in very low birth weight infants following discharge from the neonatal unit.
Topics: Cardiac Catheterization; Cardiovascular Agents; Ductus Arteriosus, Patent; Electrocardiography; Epid | 2009 |
Neurodevelopmental outcome of premature infants after exposure to antenatal indomethacin.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Central Nervous System; Child Development; Cohort St | 2008 |
Blockade of chlorpropamide-alcohol flushing by indomethacin suggests an association between prostaglandins and diabetic vascular complications.
Topics: Blood Vessels; Chlorpropamide; Diabetes Mellitus; Diabetic Angiopathies; Ethanol; Face; Female; Huma | 1980 |
PG-synthetase inhibitors in obstetrics and after.
Topics: Animals; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, | 1980 |
Prostaglandin synthase inhibitors in preterm labour.
Topics: Ductus Arteriosus; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy | 1980 |
On reducing prematurity: the hospital's role.
Topics: 17 alpha-Hydroxyprogesterone Caproate; Adrenergic beta-Agonists; Female; Hospital Departments; Human | 1982 |
Tocolytics.
Topics: Adrenergic beta-Agonists; Blood Glucose; Female; Fetal Distress; Humans; Indomethacin; Infant, Newbo | 1983 |
Effect of histamine receptor antagonists and indomethacin on implantation in the rabbit.
Topics: Aminopyridines; Animals; Capillary Permeability; Cimetidine; Drug Combinations; Drug Interactions; E | 1983 |
Treatment of premature labor contractions with combined ritodrine and indomethacine.
Topics: Adolescent; Adult; Apgar Score; Birth Weight; Drug Therapy, Combination; Female; Humans; Indomethaci | 1983 |
A survey of tocolytic drug treatment in preterm labour.
Topics: Adrenal Cortex Hormones; Adrenergic beta-Agonists; Attitude of Health Personnel; Belgium; Cervix Ute | 1984 |
Absence of teratogenicity of indomethacin in ovarian hyperstimulation syndrome.
Topics: Adult; Chorionic Gonadotropin; Female; Fertilization; Humans; Indomethacin; Infant, Newborn; Menotro | 1984 |
Modulation of natural killer sensitivity of murine trophoblast cells by tumor promoter and interferon.
Topics: Animals; Cell Line; Cells, Cultured; Cycloheximide; Cytotoxicity, Immunologic; Female; Indomethacin; | 1982 |
The vasoactivity of the fetal lamb ductus arteriosus studied in utero.
Topics: Adenosine; Aminophylline; Angiotensins; Animals; Autonomic Agents; Bucladesine; Cyclooxygenase Inhib | 1983 |
Prostaglandin stimulation of ornithine decarboxylase activity in mammary gland explants from mid-pregnant mice.
Topics: 1-Methyl-3-isobutylxanthine; 6-Ketoprostaglandin F1 alpha; Alprostadil; Animals; Carboxy-Lyases; Din | 1983 |
Alpha-fetoprotein inhibits macrophage expression of Ia antigens.
Topics: alpha-Fetoproteins; Amniotic Fluid; Animals; Cell Survival; Female; Histocompatibility Antigens Clas | 1984 |
Effect of indomethacin and prostaglandin F2 alpha on incorporation of [3H]uridine by preimplantation mouse embryo.
Topics: Animals; Dinoprost; Drug Interactions; Embryo, Mammalian; Embryonic Development; Female; Indomethaci | 1984 |
Strong suppression by mononuclear leukocytes from human newborns on maternal leukocytes: mediation by prostaglandins.
Topics: 8,11,14-Eicosatrienoic Acid; Cell Communication; Female; Humans; Indomethacin; Infant, Newborn; Leuk | 1982 |
Effects of indomethacin and prostaglandins E2, I2, and D2 on the fetal circulation.
Topics: Animals; Blood Circulation; Dinoprostone; Epoprostenol; Female; Fetus; Indomethacin; Pregnancy; Pros | 1983 |
[Indomethacin and fetal renal function. Reversible oligo-amnion after termination of therapy].
Topics: Adult; Amnion; Diuresis; Female; Fetus; Humans; Indomethacin; Kidney; Pregnancy; Prenatal Diagnosis | 1983 |
LH receptors in ovine corpora lutea in relation to various physiological states and effects PGF-2 alpha on LH-induced steroidogenesis in vitro.
Topics: 20-alpha-Dihydroprogesterone; Animals; Corpus Luteum; Estrus; Female; In Vitro Techniques; Indometha | 1981 |
Ornithine decarboxylase activity in the artificially stimulated decidual cell reaction in the mouse uterus.
Topics: Animals; Carboxy-Lyases; Cyclic AMP; Decidua; Diamines; Female; Indomethacin; Mice; Mice, Inbred ICR | 1981 |
Comparison of inhibition of bone resorption and escape with calcitonin and dibutyryl 3',5' cyclic adenosine monophosphate.
Topics: Animals; Bone and Bones; Bone Resorption; Bucladesine; Calcitonin; Calcium; Cells, Cultured; Dose-Re | 1981 |
The treatment of threatened premature labor by drugs.
Topics: Bucladesine; Cyclic AMP; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prosta | 1980 |
Effect of physical stress on sensitivity of lymphocytes to inhibition by prostaglandin E2.
Topics: Cell Adhesion; Coronary Artery Bypass; Cyclic AMP; Female; Humans; Indomethacin; Labor, Obstetric; L | 1981 |
Development and regulation of the prostaglandin F2 alpha receptor in the rat ovary.
Topics: Animals; Chorionic Gonadotropin; Estrus; Female; Indomethacin; Ovary; Pregnancy; Prostaglandins F; R | 1981 |
The ontogeny of the thyrotropin-thyroid axis in early bovine embryos.
Topics: Adenosine; Animals; Bucladesine; Cattle; Dinoprostone; Embryo, Mammalian; Female; Gestational Age; I | 1981 |
pH dependent inhibition of serum oxytocinase activity by prostaglandins and cyclic GMP.
Topics: Aminopeptidases; Anilides; Cyclic GMP; Cysteine; Cystinyl Aminopeptidase; Female; Humans; Hydrogen-I | 1982 |
The effects of indomethacin on uterine activity and prostaglandin (PG) concentrations during labor induced by administering ACTH to fetal sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Adrenocorticotropic Hormone; Animals; Cyclic AMP; Extraembryonic Membr | 1982 |
Effects of Cloprostenol administration on neutral lipid and prostaglandin F metabolism by porcine luteal tissue.
Topics: Animals; Bucladesine; Cloprostenol; Corpus Luteum; Cyclic AMP; Dinoprost; Estrus; Female; Indomethac | 1984 |
Blastocyst attachment in the ovariectomized rat treated with an intrauterine injection of luteinizing hormone-releasing hormone (LRH).
Topics: Animals; Blastocyst; Castration; Embryo Implantation; Female; Gonadotropin-Releasing Hormone; Indome | 1983 |
Prostacyclin producing activity of human umbilical, placental and uterine vessels.
Topics: Adult; Blood Vessels; Epoprostenol; Female; Humans; Indomethacin; Placenta; Platelet Aggregation; Pr | 1983 |
Inhibition of glucose-induced insulin secretion by indomethacin and sodium salicylate in the fetal lamb.
Topics: Animals; Blood Glucose; Dose-Response Relationship, Drug; Female; Fetal Blood; Fetus; Glucose; Indom | 1984 |
Ability of indomethacin to alter prostaglandin metabolite concentrations and to enhance the function of corpora lutea induced in postpartum suckled beef cows.
Topics: Animals; Cattle; Corpus Luteum; Dinoprost; Female; Indomethacin; Lactation; Ovulation Induction; Pit | 1984 |
Structural and functional evidence for the denervation of human myometrium during pregnancy.
Topics: Adult; Atropine; Autonomic Nervous System; Biopsy; Cesarean Section; Cytoplasm; Electric Stimulation | 1984 |
A variant of Bartter's syndrome. Bartter's syndrome associated with hydramnios, prematurity, hypercalciuria and nephrocalcinosis.
Topics: Bartter Syndrome; Calcium; Child, Preschool; Female; Humans; Hyperaldosteronism; Indomethacin; Infan | 1984 |
Dietary restriction alters the "in vitro" spontaneous or oxytocin-induced contractions of uterine smooth muscle from estrous rats. Possible participation of prostaglandins.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Estru | 1983 |
Evidence for a role of prostaglandins in the antepartum release of relaxin in the pregnant rat.
Topics: Animals; Corpus Luteum; Cyclooxygenase Inhibitors; Dinoprost; Female; Gestational Age; Indomethacin; | 1983 |
Effect of indomethacin on reproduction under laboratory and field conditions in deermice (Peromyscus maniculatus).
Topics: Animals; Animals, Laboratory; Cyclooxygenase Inhibitors; Female; Indomethacin; Male; Peromyscus; Pre | 1983 |
Prostaglandin release by zygotes and endometria of pregnant rabbits.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blastocyst; Culture Media; Endometrium; Female; Indome | 1983 |
Identification of phospholipid platelet-activating factor (1-0-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in human amniotic fluid and urine.
Topics: Amniotic Fluid; Arachidonic Acid; Arachidonic Acids; Calcium; Female; Humans; Indomethacin; Platelet | 1983 |
Evidence for a possible role of prostaglandins in implantation in rats.
Topics: Animals; Cyclooxygenase Inhibitors; Embryo Implantation; Female; Indomethacin; Pregnancy; Prostaglan | 1983 |
Lipoxygenase activity in human uterine and intrauterine tissues: new prospects for control of prostacyclin production in pre-eclampsia.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arach | 1983 |
In vitro contractile responses of the uterus from 'restricted diet' rats to adrenoceptor agonists. Influence of cyclo-oxygenase inhibitors.
Topics: Animal Feed; Animals; Aspirin; Cyclooxygenase Inhibitors; Diet; Estrus; Female; In Vitro Techniques; | 1983 |
The modulation of decidual cells proliferation and differentiation by progesterone and prostaglandins.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Decidua; DNA Replication; Female; Ind | 1983 |
Conversion of arachidonic acid to lipoxygenase products by human fetal tissues.
Topics: Arachidonic Acid; Arachidonic Acids; Catechols; Female; Fetus; Humans; In Vitro Techniques; Indometh | 1983 |
Prostacyclin, prostaglandin F2 alpha and progesterone production by bovine luteal cells during the estrous cycle.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Corpus Luteum; D | 1983 |
The effect of prostaglandin synthetase inhibitor on pressor reaction during intravenous infusion of angiotensin II in pregnant rabbits.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Female; | 1983 |
Further evidence for a role of arachidonic acid in glucocorticoid teratogenic action in the palate.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Cleft Palate; Cortisone; Female; Hydr | 1983 |
Calcium dobesilate (Doxium) as a prostaglandin synthetase inhibitor in pregnant human myometrium in vitro.
Topics: Benzenesulfonates; Calcium Dobesilate; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; | 1984 |
Prostaglandins and related compounds -- a general physiologic control system.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aspirin; Diet; Epoprostenol; Fatty Acids; Female; Huma | 1983 |
Orthostatic hypotension: diagnosis and treatment.
Topics: Blood Pressure; Diagnosis, Differential; Dizziness; Female; Fludrocortisone; Humans; Hypotension, Or | 1984 |
Serum protein binding of diazepam, desmethyldiazepam, furosemide, indomethacin, warfarin, and phenobarbital in human fetus, mother, and newborn infant.
Topics: Blood Proteins; Diazepam; Fatty Acids, Nonesterified; Female; Fetal Blood; Furosemide; Humans; Indom | 1983 |
Indomethacin-induced fetal breathing: mechanism and site of action.
Topics: Animals; Biomechanical Phenomena; Carbon Dioxide; Female; Fetal Blood; Fetus; Hydrogen-Ion Concentra | 1984 |
Cyclic response of hypophysectomized rats to ovulation induced by LHRH agonist: mediation by prostaglandins.
Topics: Acetates; Adrenalectomy; Animals; Cyclooxygenase Inhibitors; Dinoprost; Estrus; Female; Gonadotropin | 1984 |
Indomethacin and the cardiopulmonary adaptations of transition.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Female; Indomethacin; Lung; Perfusion; Pregnancy | 1984 |
Inability of newborns' or pregnant women's monocytes to suppress pokeweed mitogen-induced responses.
Topics: B-Lymphocytes; Cell Adhesion; Cell Differentiation; Concanavalin A; Dinoprostone; Female; Fetal Bloo | 1982 |
[Action of indomethacin on fetal development].
Topics: Animals; Dose-Response Relationship, Drug; Embryo Implantation; Female; Fetal Death; Fetus; Indometh | 1984 |
[Artificial dilatation of the uterine cervix of the pregnant rat by means of hyaluronidase and indomethacin].
Topics: Animals; Cervix Uteri; Dilatation; Drug Combinations; Female; Hyaluronoglucosaminidase; Indomethacin | 1984 |
Fetal surgery in the primate II. Uterine electromyographic response to operative procedures and pharmacologic agents.
Topics: Amniocentesis; Anesthesia, Obstetrical; Animals; Catheterization; Electrodes, Implanted; Electromyog | 1984 |
Effect of indomethacin in vivo on prostaglandin content of several rabbit tissues.
Topics: Animals; Blastocyst; Female; Indomethacin; Kidney; Peritoneal Cavity; Pregnancy; Prostaglandins E; P | 1984 |
Prostaglandin synthesis inhibition in persistent pulmonary hypertension of the newborn.
Topics: Animals; Blood Pressure; Ductus Arteriosus, Patent; Female; Fetus; Humans; Hypertension, Pulmonary; | 1984 |
RDS prophylaxis in preterm labor: corticosteroids and beta-mimetics association-indications and limits.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adrenal Cortex Hormones; Drug Therapy, Combination; Female; Huma | 1984 |
Delayed luteolysis and suppression of the pulsatile release of oxytocin after indomethacin treatment in the goat.
Topics: Animals; Corpus Luteum; Dinoprost; Estrus; Female; Goats; Indomethacin; Injections, Subcutaneous; Lu | 1984 |
Do luteinized unruptured follicles secrete progesterone in mature female rats.
Topics: Animals; Corpus Luteum; Estrus; Female; Indomethacin; Luteinizing Hormone; Ovarian Follicle; Ovulati | 1984 |
Urinary excretion of 2,3-dinor-thromboxane B2 in man under normal conditions, following drugs and during some pathological conditions.
Topics: Acetaminophen; Adult; Amino Acid Metabolism, Inborn Errors; Aspirin; Circadian Rhythm; Diabetes Mell | 1984 |
Myometrial response to prostaglandins during labor.
Topics: Dinoprost; Dinoprostone; Female; Humans; In Vitro Techniques; Indomethacin; Labor, Obstetric; Myomet | 1984 |
Endometrial prostaglandins and phospholipase activity related to implantation in rabbits: effects of dexamethasone.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dexamethasone; Dinoprost; Dinoprostone; Embryo Implantation; | 1984 |
Prostaglandin E2 and prostaglandin F2 regulation of triglyceride levels in uterine smooth muscle from restricted-diet estrous and diestrous rats.
Topics: Animals; Diestrus; Diet; Dinoprost; Dinoprostone; Estrus; Female; In Vitro Techniques; Indomethacin; | 1984 |
Prostaglandin synthesis in rat embryo tissue: the effect of non-steroidal anti-inflammatory drugs in vivo and ex vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Anti-Inflammatory Agents; Aspirin; Dinoprost; Embryo, Mammali | 1984 |
Decreased contractility of the ductus arteriosus in experimental pulmonic stenosis.
Topics: Animals; Dinoprostone; Disease Models, Animal; Ductus Arteriosus; Female; Hemodynamics; Indomethacin | 1984 |
Possible role of prostaglandins in the regulation of food intake in the newborn rat.
Topics: Animals; Animals, Newborn; Animals, Suckling; Aspirin; Body Weight; Dinoprost; Dinoprostone; Eating; | 1984 |
In vitro influence of steroids, histamine, adrenaline and oxytocin on secretion of prostaglandins PGE2 and PGF2 alpha by human fetal membranes.
Topics: Cells, Cultured; Corticosterone; Dinoprost; Dinoprostone; Epinephrine; Estradiol; Extraembryonic Mem | 1984 |
Macrophage-derived growth factor for osteoblast-like cells and chondrocytes.
Topics: Animals; Cartilage; Cell Division; Chromatography, Gel; DNA Replication; Female; Indomethacin; Insul | 1984 |
Effect of indomethacin on stretch-induced uterine activity in the post-partum.
Topics: Female; Humans; Indomethacin; Labor, Obstetric; Muscle Contraction; Muscle Relaxation; Postpartum Pe | 1983 |
Prolactin secretion by human chorion-decidua in vitro: influences of mode of delivery and agents that modify prostaglandin synthesis.
Topics: Arachidonic Acids; Cesarean Section; Chorion; Decidua; Female; Humans; Indomethacin; Male; Oxytocin; | 1983 |
Indomethacin and the fetal renal nonfunction syndrome.
Topics: Abnormalities, Drug-Induced; Adult; Face; Female; Humans; Indomethacin; Infant, Newborn; Kidney; Mat | 1983 |
Constriction of fetal ductus arteriosus by non-steroidal anti-inflammatory drugs.
Topics: Age Factors; Animals; Anti-Inflammatory Agents; Ductus Arteriosus; Female; Indomethacin; Pregnancy; | 1983 |
[Effects of indomethacin on renal and uterine blood flow and pressor responsiveness to angiotensin II or norepinephrine in pregnant dogs].
Topics: Angiotensin II; Animals; Blood Pressure; Blood Volume; Dogs; Female; Indomethacin; Norepinephrine; P | 1983 |
Unexpected cardiac pathology in pregnant women treated with beta-adrenergic agents (ritodrine).
Topics: Adult; Cardiomyopathies; Cesarean Section; Dyspnea; Female; Heart Septal Defects, Atrial; Humans; In | 1983 |
Deciduoma formation in persistent estrous rats produced by neonatal androgenization.
Topics: Androgens; Animals; Castration; Decidua; Estrus; Female; Indomethacin; Organ Size; Pregnancy; Prosta | 1983 |
Luteal function after ovulation blockade by intrafollicular injection of indomethacin in the ewe.
Topics: Animals; Corpus Luteum; Estrus; Female; Indomethacin; Ovarian Follicle; Ovulation; Pregnancy; Proges | 1983 |
Effect of treatment of estrous ewes with indomethacin on the distribution of ovarian blood to the periovulatory follicle.
Topics: Animals; Estrus; Female; Indomethacin; Ovarian Follicle; Ovary; Pregnancy; Regional Blood Flow; Shee | 1983 |
Prostaglandin output in relation to parturition by cells dispersed from human intrauterine tissues.
Topics: 6-Ketoprostaglandin F1 alpha; Cell Survival; Cesarean Section; Decidua; Extraembryonic Membranes; Fe | 1983 |
Effect of indomethacin on fetal lung liquid formation.
Topics: Animals; Body Water; Female; Fetus; Indomethacin; Lung; Pregnancy; Sheep | 1984 |
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; In | 1984 |
Decidual cell reaction in ovariectomized-adrenalectomized rats.
Topics: Adrenalectomy; Animals; Castration; Corticosterone; Decidua; Female; Indomethacin; Pregnancy; Prosta | 1984 |
Further study of the inhibition of premature labor by indomethacin. Part I.
Topics: Adolescent; Adult; Female; Gestational Age; Humans; Indomethacin; Obstetric Labor, Premature; Pregna | 1984 |
Effects of oxytocin on cervical and uterine connective tissue.
Topics: Arginine Vasopressin; Cervix Uteri; Collagen; Connective Tissue; Estradiol; Female; Humans; Indometh | 1984 |
Rabbit blastocysts accumulate [3H]prostaglandins in vitro.
Topics: Analysis of Variance; Animals; Blastocyst; Chromatography, High Pressure Liquid; Female; In Vitro Te | 1984 |
Site of action of indomethacin on implantation in the rabbit.
Topics: Animals; Blastocyst; Embryo Implantation; Embryo Transfer; Endometrium; Female; Indomethacin; Pregna | 1984 |
Ulcerogenic effects of indomethacin in pregnant rats.
Topics: Animals; Female; Indomethacin; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Stomach Ulc | 1984 |
The response of the lamb ductus venosus to prostaglandins and inhibitors of prostaglandin and thromboxane synthesis.
Topics: Animals; Animals, Newborn; Depression, Chemical; Dinoprostone; Epoprostenol; Female; Fetal Organ Mat | 1982 |
Hydramnios and observations in Bartter's syndrome.
Topics: Adult; Bartter Syndrome; Female; Humans; Hyperaldosteronism; Indomethacin; Infant; Male; Polyhydramn | 1982 |
Oligohydramnios and transient neonatal anuria: a possible association with the maternal use of prostaglandin synthetase inhibitors.
Topics: Adult; Anuria; Arthritis, Juvenile; Blood Urea Nitrogen; Creatinine; Cyclooxygenase Inhibitors; Fema | 1980 |
Initiation of human parturition. XII. Biosynthesis and metabolism of prostaglandins in human fetal membranes and uterine decidua.
Topics: Amnion; Aspirin; Cesarean Section; Chorion; Cyclooxygenase Inhibitors; Decidua; Extraembryonic Membr | 1981 |
Trapped blood elements within the decidua of the rat pregnant uterus generate a lipoxygenase product(s) which inhibits myometrial prostacyclin synthesis.
Topics: Animals; Arachidonic Acids; Blood Platelets; Decidua; Epoprostenol; Female; Indomethacin; Lipoxygena | 1981 |
Inhibition of the synthesis and secretion of decidual prolactin by arachidonic acid.
Topics: Arachidonic Acid; Arachidonic Acids; Decidua; Female; Flufenamic Acid; Humans; Indomethacin; Kinetic | 1981 |
Lectins, calcium ionophore A23187 and peanut oil as deciduogenic agents in the uterus of pseudopregnant mice: effects of tranylcypromine, indomethacin, iproniazid and propranolol.
Topics: Animals; Calcimycin; Decidua; Female; Indomethacin; Iproniazid; Lectins; Mice; Oils; Peanut Oil; Pla | 1982 |
Formation of arachidonate lipoxygenase metabolites by human fetal membranes, uterine decidua vera and placenta.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Arachidonate Lipoxygenases; Arachidonic Acids; Extraembr | 1982 |
A possible role of prostaglandin F-2 alpha in the development of ovarian follicles in guinea-pigs.
Topics: Animals; Chorionic Gonadotropin; Dinoprost; Estrus; Female; Follicle Stimulating Hormone; Guinea Pig | 1982 |
Effect of prostaglandin synthetase inhibitors on mammary blood flow during experimentally induced mastitis in lactating goats.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Flurbiprofen; Goats; Indomethacin; Lactation; Lipopolysa | 1982 |
[Fetal hydrops following indomethacin administration during pregnancy].
Topics: Adult; Edema; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Male; Mate | 1983 |
Exacerbation of Cushing's disease during pregnancy.
Topics: Adrenal Glands; Adult; Cushing Syndrome; Ductus Arteriosus, Patent; Female; Glucocorticoids; Humans; | 1983 |
Development and validation of a radioimmunoassay for prostaglandin E2 metabolite levels in plasma.
Topics: Adult; Aged; Animals; Cross Reactions; Dinoprostone; Female; Humans; Immune Sera; Indomethacin; Infu | 1983 |
[The effect of indomethacin on placental permeability and the fetal lung circulation].
Topics: Animals; Capillary Permeability; Female; Fetus; Indomethacin; Maternal-Fetal Exchange; Placenta; Pre | 1983 |
Drug-induced changes in fetal breathing activity and sleep state.
Topics: Animals; Caffeine; Doxapram; Female; Fetus; Indomethacin; Pilocarpine; Pregnancy; Respiration; Sheep | 1983 |
Accumulation of several basement membrane proteins in glomeruli of patients with preeclampsia and other hypertensive syndromes of pregnancy. Possible role of renal prostaglandins and fibronectin.
Topics: Basement Membrane; Collagen; Female; Fibrin; Fibronectins; Glycoproteins; Humans; Hypertension; Indo | 1983 |
Studies on the involvement of prostaglandins in implantation in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Embryo Implantation; Female; Gas Chromatography-Mass Spectrom | 1981 |
Inhibitors of prostaglandin synthesis, tracheal fluid, and surfactant in fetal lambs.
Topics: Animals; Body Fluids; Female; Hydrogen-Ion Concentration; Indomethacin; Lung; Oxygen; Phosphatidylch | 1981 |
Chronic paroxysmal hemicrania (CPH). The clinical manifestations. A review.
Topics: Age Factors; Chronic Disease; Female; Humans; Indomethacin; Male; Migraine Disorders; Otorhinolaryng | 1980 |
The role and regulation of prostaglandins in late pregnancy and parturition in sheep.
Topics: Adrenal Glands; Animals; Dinoprost; Dinoprostone; Female; Fetus; Indomethacin; Labor, Obstetric; Pre | 1981 |
Bone resorptive factor produced by osteosarcoma cells with osteoblastic features is PGE2.
Topics: Animals; Bone Neoplasms; Bone Resorption; Cell Line; Chromatography, Thin Layer; Culture Media; Dino | 1981 |
Measurement of prostaglandins in embryonic tissue using radioimmunoassay.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Embryo, Mammalian; Female; Indomethacin; Male; NAD | 1981 |
Thromboxane B2, 6-keto-prostaglandin F1 alpha, and prostaglandin F2 alpha production by contracting pregnant rate uteri in vitro.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Dinoprost; Female; Gestational Age; Imidazoles; Indomethacin; | 1982 |
The effect and interaction of bradykinin and prostaglandins on protein and collagen production by lung fibroblasts.
Topics: Bradykinin; Collagen; Dinoprostone; Drug Synergism; Female; Fibroblasts; Humans; Indomethacin; Lung; | 1982 |
Comparative studies of prostaglandins F2 alpha and E2 in late cyclic and early pregnant sheep: in vitro synthesis by endometrium and conceptus effects of in vivo indomethacin treatment on establishment of pregnancy.
Topics: Animals; Corpus Luteum; Dinoprost; Dinoprostone; Endometrium; Female; Fetus; Indomethacin; Organ Siz | 1982 |
Effects of systemic administration of indomethacin to cyclic ewes on endometrial concentrations of prostaglandins effects on estrous cycle length and on progesterone, luteinizing hormone and prolactin patterns.
Topics: Animals; Dinoprost; Dinoprostone; Endometrium; Estradiol; Estrus; Female; Indomethacin; Luteinizing | 1982 |
Induction of decidualization in rats by the intrauterine infusion of prostaglandins.
Topics: Animals; Decidua; Dinoprost; Dinoprostone; Female; Indomethacin; Organ Size; Pregnancy; Prostaglandi | 1982 |
Inhibition of ovulation by indomethacin in rats.
Topics: Animals; Dinoprost; Female; Indomethacin; Ovulation; Pregnancy; Prostaglandins F; Rats; Time Factors | 1982 |
Oxytocin, prostaglandins, and contractility of the human uterus at term pregnancy.
Topics: Adult; Cesarean Section; Dinoprost; Dinoprostone; Female; Humans; Indomethacin; Oxytocin; Parity; Pr | 1982 |
Inhibition of artificially induced decidual cell reaction by indomethacin in the mature oophorectomized rat.
Topics: Animals; Castration; Decidua; Dinoprost; Endometrium; Female; Indomethacin; Organ Size; Ovary; Pregn | 1982 |
Ductus arteriosus: developmental response to endogenous prostaglandins, oxygen, and indomethacin.
Topics: Animals; Ductus Arteriosus; Ductus Arteriosus, Patent; Epoprostenol; Female; Gestational Age; Indome | 1980 |
Regulation of plasma renin in developing piglets.
Topics: Age Factors; Animals; Animals, Newborn; Female; Indomethacin; Pregnancy; Prostaglandins; Renin; Sara | 1980 |
Role of arachidonic acid metabolites in the hypothalamic control of ovulation in the rat.
Topics: Acetaminophen; Animals; Arachidonic Acids; Aspirin; Female; Gonadotropin-Releasing Hormone; Hypothal | 1980 |
The role of prostaglandins in endotoxemia and comparisons in response in the nonpregnant, maternal, and fetal models. II. Alterations in prostaglandin physiology in the nonpregnant, pregnant, and fetal experimental animal.
Topics: Animals; Endotoxins; Escherichia coli; Female; Fetus; Indomethacin; Pre-Eclampsia; Pregnancy; Prosta | 1981 |
The spontaneous motility and the prostaglandin E-like material generation is different in the implantation and in the non-implantation regions of the uterus isolated from rats in natural estrus. Influences of indomethacin.
Topics: Animals; Dinoprost; Dinoprostone; Embryo Implantation; Epoprostenol; Estrus; Female; Indomethacin; M | 1981 |
Prostaglandin E2, plasma renin activity, and renal function throughout rabbit pregnancy.
Topics: Animals; Creatinine; Female; Glomerular Filtration Rate; Indomethacin; Kidney; Pregnancy; Prostaglan | 1982 |
Effect of platelet-generated thromboxane on contractions of the pregnant rat uterus.
Topics: Animals; Arachidonic Acids; Biological Assay; Blood Platelets; Epoprostenol; Female; Humans; Imidazo | 1982 |
Effects of inhibition of prostaglandin synthesis on fetal renal function.
Topics: Animals; Female; Fetus; Glomerular Filtration Rate; Indomethacin; Kidney; Kidney Concentrating Abili | 1981 |
Fetal surgery in the primate I. Anesthetic, surgical, and tocolytic management to maximize fetal-neonatal survival.
Topics: Anesthetics; Animals; Female; Fetal Death; Fetal Viability; Fetus; Indomethacin; Macaca; Macaca fasc | 1982 |
Plasma concentrations of prolactin, progesterone, relaxin and oestradiol-17 beta in sows treated with progesterone, bromocriptine or indomethacin during late pregnancy.
Topics: Animals; Bromocriptine; Estradiol; Female; Gonadal Steroid Hormones; Indomethacin; Labor, Obstetric; | 1982 |
[Changes in the reactivity of the uterine musculature to oxytocin in endogenous inhibition of prostaglandin synthesis].
Topics: Animals; Female; In Vitro Techniques; Indomethacin; Labor, Obstetric; Oxytocin; Pregnancy; Pregnancy | 1982 |
Maternal essential fatty acid supplementation increases zinc absorption in neonatal rats: relevance to the defect in zinc absorption in acrodermatitis enteropathica.
Topics: Acrodermatitis; Animals; Arachidonic Acids; Fatty Acids, Essential; Female; Gastrointestinal Disease | 1982 |
Hydrops fetalis caused by maternal indomethacin treatment.
Topics: Adult; Diseases in Twins; Edema; Female; Heart Defects, Congenital; Humans; Indomethacin; Infant, Ne | 1982 |
Intrauterine delivery of indomethacin from a silastic device: effect on the preimplantation embryo and implantation.
Topics: Animals; Delayed-Action Preparations; Embryo Implantation; Embryonic Development; Female; Indomethac | 1982 |
[Influences of indomethacin on the cardiovascular and metabolic systems of fetuses].
Topics: Amniotic Fluid; Animals; Female; Fetus; Hemodynamics; Indomethacin; Liver; Lung; Maternal-Fetal Exch | 1982 |
Luteotropic and antiluteolytic activities of the rabbit conceptus.
Topics: Animals; Blastocyst; Chorionic Gonadotropin; Corpus Luteum; Corpus Luteum Maintenance; Estrogens; Fe | 1982 |
Indomethacin delays zona-shedding and implantation in the ovariectomized progesterone-treated hamster.
Topics: Animals; Blastocyst; Castration; Cricetinae; Embryo Implantation; Female; Indomethacin; Litter Size; | 1982 |
[Treatment of premature labor with indomethacin and its effect on the fetus].
Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature | 1982 |
Effect of some nonsteroidal substances on decidual cell reaction in immature rats.
Topics: Animals; Centchroman; Clomiphene; Decidua; Female; Indomethacin; Pregnancy; Pyrilamine; Rats; Seroto | 1982 |
Adult Still's disease associated with pregnancy.
Topics: Adult; Arthritis, Juvenile; Female; Humans; Indomethacin; Prednisone; Pregnancy; Pregnancy Complicat | 1982 |
Intrauterine migration of the porcine embryo--interaction of embryo, uterine flushings and indomethacin on myometrial function in vitro.
Topics: Animals; Culture Media; Embryo, Mammalian; Embryonic Development; Estradiol; Female; Gestational Age | 1982 |
[Premature labor].
Topics: Child, Preschool; Chile; Female; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Ob | 1982 |
Prostaglandin synthesis by murine mammary gland is modified by the state of the estrus cycle.
Topics: Animals; Estrus; Female; Indomethacin; Mammary Glands, Animal; Mice; Pregnancy; Prostaglandins E; Pr | 1980 |
[Biochemical studies on acemetacin/Experimental tests in animals (author's transl)].
Topics: Animals; Anti-Inflammatory Agents; Bile; Biotransformation; Cats; Dogs; Female; Guinea Pigs; Indolea | 1980 |
[Toxicology of acemetacin].
Topics: Aging; Animals; Anti-Inflammatory Agents; Cats; Dogs; Female; Indoleacetic Acids; Indomethacin; Leth | 1980 |
Fluid retention by the rabbit oviduct.
Topics: Animals; Body Fluids; Chorionic Gonadotropin; Estradiol; Estrus; Fallopian Tubes; Female; Indomethac | 1980 |
Estradiol regulation of the frequency and site of origin of uterine contractions in news.
Topics: Animals; Cycloheximide; Dopamine; Estradiol; Estrus; Female; Indomethacin; Norepinephrine; Pregnancy | 1980 |
Effects of indomethacin on fetal rat lungs: a possible cause of persistent fetal circulation (PFC).
Topics: Animals; Animals, Newborn; Female; Fetus; Humans; Indomethacin; Infant, Newborn; Lung; Persistent Fe | 1981 |
Effect of indomethacin on the interestrous interval of intact and hysterectomized pseudopregnant mice.
Topics: Anestrus; Animals; Estrus; Female; Hysterectomy; Indomethacin; Meclofenamic Acid; Mice; Pharmaceutic | 1981 |
Corpus luteum function after indomethacin treatment during the estrous cycle and following hysterectomy in the gilt.
Topics: Animals; Corpus Luteum; Corpus Luteum Maintenance; Dinoprost; Estrus; Ethanol; Female; Hysterectomy; | 1981 |
An intrauterine silastic system for the sustained release of indomethacin.
Topics: Animals; Body Weight; Estrus; Female; Indomethacin; Inflammation; Intrauterine Devices; Intrauterine | 1981 |
[Effect of copper ions on the contractility of rabbit's myometrium in vitro].
Topics: Animals; Copper; Diestrus; Female; In Vitro Techniques; Indomethacin; Naproxen; Pregnancy; Rabbits; | 1981 |
The separate uterotonic and prostaglandin-releasing actions of oxytocin. Evidence and comparison with angiotensin and methacholine in the isolated rat uterus.
Topics: Angiotensin II; Animals; Female; Indomethacin; Methacholine Compounds; Oxytocin; Pregnancy; Prostagl | 1980 |
Inhibition of prostaglandin synthesis by zidometacin.
Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acids; Diarrhea; Female; Gastric Mucosa; In Vitro Tec | 1981 |
Effect of indomethacin and aspirin on uterine activity in pregnant rats: comparison of circular and longitudinal muscle.
Topics: Animals; Aspirin; Endometrium; Female; Indomethacin; Myometrium; Organ Specificity; Pregnancy; Pregn | 1981 |
Effects of prostaglandins and inhibitors of prostaglandin synthesis in the fetus and newborn infant.
Topics: Animals; Blood Circulation; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fetus; Humans; Ind | 1981 |
Effects of prostaglandin D2 on perinatal circulation.
Topics: Aging; Animals; Animals, Newborn; Blood Circulation; Female; Fetus; Goats; Indomethacin; Lung; Pregn | 1981 |
Placental transfer of indomethacin in the rabbit and sheep.
Topics: Amniotic Fluid; Animals; Blood Proteins; Female; Half-Life; Indomethacin; Maternal-Fetal Exchange; P | 1981 |
Pharmacokinetics of indomethacin in the neonate. Relation of plasma indomethacin levels to response of the ductus arteriosus.
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Half-Life; Humans; Indomethacin; Kinetics; Mal | 1981 |
Uterine blood flow distribution after indomethacin infusion in the pregnant rabbit.
Topics: Animals; Female; Indomethacin; Placenta; Pregnancy; Pregnancy, Animal; Prostaglandins; Rabbits; Regi | 1981 |
[Trans-placental transfer of four anti-inflammatory agents. A study carried out by in vitro perfusion (author's transl)].
Topics: Anti-Inflammatory Agents; Female; Humans; Indomethacin; Ketoprofen; Oxyphenbutazone; Perfusion; Phen | 1981 |
Effect of indomethacin dexamethasone-induced parturition in swine.
Topics: Animals; Dexamethasone; Female; Indomethacin; Labor, Induced; Pregnancy; Pregnancy, Animal; Progeste | 1981 |
Antifertility effect of azastene mediated by prostaglandin.
Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Androstenols; Animals; Female; Indomethacin; | 1981 |
Indomethacin--placental transfer, cytotoxicity, and teratology in the rat.
Topics: Abnormalities, Drug-Induced; Animals; Chromatography, High Pressure Liquid; Embryo, Mammalian; Femal | 1981 |
A comparison of plasma prostaglandin levels in term and preterm labour.
Topics: Female; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; P | 1981 |
[Combined indomethacin and ritodrine treatment in the prevention of pre-term labor. Preventive note].
Topics: Adult; Drug Therapy, Combination; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnanc | 1980 |
[Indomethacin in the prevention of pre-term labor].
Topics: Adult; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy | 1980 |
[Maternal treatment with indomethacin and severe neonatal pulmonary hypertension (author's transl)].
Topics: Female; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; | 1981 |
Effect of indomethacin and prostaglandin F2 alpha on parturition in swine.
Topics: Animals; Corpus Luteum; Female; Fetal Death; Indomethacin; Labor, Obstetric; Pregnancy; Progesterone | 1981 |
Indomethacin metabolism in isolated neonatal and fetal rabbit hepatocytes.
Topics: Animals; Animals, Newborn; Female; Fetus; Glucuronates; In Vitro Techniques; Indomethacin; Liver; Pr | 1981 |
[Has indomethacin an inhibiting effect on uterine contractions?].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Labor, Obstetric; Pregnancy; Uterine Contraction | 1981 |
Effect of intrauterine administration of antiprostaglandin drugs on implantation in the rat.
Topics: Animals; Aspirin; Embryo Implantation; Female; Ibuprofen; Indomethacin; Injections; Pregnancy; Prost | 1981 |
Etamsylate as inhibitor of prostaglandin biosynthesis in pregnant human myometrium in vitro.
Topics: Benzenesulfonates; Ethamsylate; Female; Humans; In Vitro Techniques; Indomethacin; Microsomes; Myome | 1981 |
The measurement of placental drug clearance in near-term sheep: indomethacin.
Topics: Animals; Chromatography, Thin Layer; Diffusion; Female; Gestational Age; Indomethacin; Maternal-Feta | 1980 |
Adult Still's disease associated with pregnancy.
Topics: Adult; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Prednisone; Pregnancy; Pregnancy | 1980 |
Inhibition of fetal bone growth and augmentation of PGE2 resorptive response by indomethacin.
Topics: Animals; Bone and Bones; Bone Resorption; Calcium; Dose-Response Relationship, Drug; Female; Fetus; | 1980 |
Gap junction formation in myometrium: control by estrogens, progesterone, and prostaglandins.
Topics: Animals; Arachidonic Acids; Eicosanoic Acids; Estrogens; Female; Freeze Fracturing; In Vitro Techniq | 1980 |
[Prostaglandin inhibitors and their use in the obstetrical and gynecological clinic].
Topics: Animals; Aspirin; Ethanol; Female; Fertility; Genital Diseases, Female; Humans; In Vitro Techniques; | 1980 |
Oligohydramnion, meconium and perinatal death concurrent with indomethacin treatment in human pregnancy.
Topics: Adult; Amniotic Fluid; Female; Fetal Death; Humans; Indomethacin; Infant Mortality; Infant, Newborn; | 1980 |
Fetal breathing movements and inhibitors of prostaglandin synthesis.
Topics: Animals; Cerebral Cortex; Electroencephalography; Female; Fetus; Humans; Indomethacin; Meclofenamic | 1980 |
Prostaglandins and implantation in the rat.
Topics: Animals; Capillary Permeability; Embryo Implantation; Female; Indomethacin; Pregnancy; Prostaglandin | 1980 |
The effects of repeated doses of indomethacin on fetal rabbit mortality and on the patency of the ductus arteriosus.
Topics: Animals; Constriction, Pathologic; Ductus Arteriosus; Female; Fetal Death; Fetus; Indomethacin; Mate | 1980 |
The use of indomethacin for amplifying PGE2-induced uterine contractions.
Topics: Animals; Drug Synergism; Female; In Vitro Techniques; Indomethacin; Pregnancy; Prostaglandins E, Syn | 1980 |
Reversal of indomethacin blockade of ovulation in gilts by prostaglandins.
Topics: Animals; Chorionic Gonadotropin; Female; Gonadotropins, Equine; Humans; Indomethacin; Ovulation; Pre | 1980 |
Does oxygen regulate prostaglandin-induced relaxation in the lamb ductus arteriosus?
Topics: Animals; Ductus Arteriosus; Female; Hypoxia; In Vitro Techniques; Indomethacin; Oxygen; Pregnancy; P | 1980 |
Clinical applications.
Topics: Abortion, Induced; Aspirin; Blood Pressure; Cardiovascular Diseases; Cervix Uteri; Digestive System; | 1980 |
Classification of threatened premature labor related to treatment with a prostaglandin inhibitor: indomethacin.
Topics: Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy; Uterine Contra | 1980 |
Timing of uterine sensitivity for the decidual cell reaction: role of prostaglandins.
Topics: Animals; Decidua; Female; Indomethacin; Pregnancy; Prostaglandins; Prostaglandins E; Pseudopregnancy | 1980 |
Ultrastructural changes of the trophoblast-epithelial complex in mice subjected to implantation blocking treatment with indomethacin.
Topics: Animals; Blastocyst; Castration; Embryo Implantation; Endometrium; Epithelium; Female; Indomethacin; | 1980 |
[Indomethacin for prevention of premature labor].
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Uterine Contraction | 1980 |
[Persistance of fetal circulation. a case associated to maternal indomethacin administration (author's transl)].
Topics: Female; Hemodynamics; Humans; Indomethacin; Infant, Newborn; Labor, Obstetric; Male; Persistent Feta | 1980 |
The degenerative effect on rabbit implantation sites by indomethacin. I. Timing of indomethacin action, possible effect on uterine proteins and the effect of replacement doses of PGF2 alpha.
Topics: Animals; Bradykinin; Embryo Implantation; Female; Fetal Resorption; Fetal Viability; Indomethacin; M | 1980 |
Angiotensin II and [Sar1, Ile5, Ala8]angiotensin II effect on contractile activity and prostaglandin production of in vitro pregnant rat uteri.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Female; Indomethacin; Pregnancy; Pregnanc | 1980 |
Effect of indomethacin on desoxycorticosterone acetate-sodium chloride-induced renal lesions in the pregnant rat and her offspring.
Topics: Animals; Desoxycorticosterone; Female; Hypertension; Indomethacin; Kidney; Pregnancy; Pregnancy Comp | 1980 |
Effects of prostaglandin F2 alpha, indomethacin, and estradiol on ovum transport and pregnancy in the golden hamster.
Topics: Animals; Cricetinae; Estradiol; Fallopian Tubes; Female; Indomethacin; Mesocricetus; Ovum; Pregnancy | 1980 |
[Persistent pulmonary hypertension in the newborn caused by prenatal use of prostaglandin inhibitors, (indomethacin). Report of a case].
Topics: Abortion, Threatened; Adult; Female; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; | 1980 |
Removal of corpora lutea in pregnant goats: effect of intrauterine indomethacin.
Topics: Abortion, Induced; Animals; Cervix Uteri; Corpus Luteum; Estradiol; Estrone; Female; Goats; Indometh | 1980 |
[Prostaglandin and threat of premature labour inhibitors. 1. The possibilities and consequences (as given in the literature) (author's transl)].
Topics: Anti-Inflammatory Agents; Female; Humans; Indomethacin; Infant, Newborn; Labor, Obstetric; Maternal- | 1980 |
Prostaglandin F2 alpha and progesterone in experimental hypogalactia in sows.
Topics: Adrenal Cortex Hormones; Animals; Estrogens; Female; Indomethacin; Iodine; Labor, Obstetric; Lactati | 1980 |
Effects of aspirin and acetaminophen in pregnancy and in the newborn.
Topics: Abnormalities, Drug-Induced; Acetaminophen; Animals; Aspirin; Blood Platelets; Female; Fetus; Humans | 1981 |
[Twin pregnancy, indomethacin and neonatal cyanosis (author's transl)].
Topics: Adult; Cyanosis; Diseases in Twins; Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, | 1980 |
Effects of angiotensin II in fetal sheep and modification of its actions by indomethacin.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Fetus; Indomethacin; Infusions, Intravenous; Placen | 1995 |
The effect of aspirin and indomethacin on prostacyclin and thromboxane production by placental tissue incubated with immunoglobulin G fractions from patients with lupus anticoagulant.
Topics: Antibodies, Antiphospholipid; Aspirin; Epoprostenol; Female; Humans; Immunoglobulin G; Indomethacin; | 1995 |
Secretion of prostaglandins and endothelin-1 by decidual endothelial cells from normal and preeclamptic pregnancies: comparison with human umbilical vein endothelial cells.
Topics: Cells, Cultured; Cesarean Section; Decidua; Endothelins; Endothelium, Vascular; Epoprostenol; Female | 1995 |
Prostacyclin contributes to nitroglycerin-mediated relaxation of human umbilical arteries.
Topics: Epoprostenol; Female; Humans; In Vitro Techniques; Indomethacin; Molsidomine; Muscle Relaxation; Mus | 1993 |
Prostaglandin E2 enhances bradykinin-stimulated release of neuropeptides from rat sensory neurons in culture.
Topics: Animals; Bradykinin; Calcitonin Gene-Related Peptide; Cells, Cultured; Chromatography, High Pressure | 1994 |
Prevention of human recombinant interleukin-1 beta (rhIL-1 beta) embryolethality with progesterone or indomethacin.
Topics: Adjuvants, Immunologic; Animals; Cytosine; Drug Interactions; Female; Fetal Death; Indomethacin; Int | 1995 |
Indomethacin and alpha-tocopheral enhanced survival in endotoxic rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Drug Evaluation, Preclinical; Drug Therapy, Combin | 1995 |
Effect of ethanol on prostacyclin, thromboxane, and prostaglandin E production in human umbilical veins.
Topics: Adult; Culture Techniques; Dose-Response Relationship, Drug; Epoprostenol; Ethanol; Female; Fetal Al | 1995 |
Changes in prostaglandin synthesis and metabolism associated with labour, and the influence of dexamethasone, RU 486 and progesterone.
Topics: Amnion; Analysis of Variance; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Ara | 1995 |
Prostaglandins and the maintenance of pregnancy in goats.
Topics: Animals; Corpus Luteum; Corpus Luteum Maintenance; Dinoprost; Dinoprostone; Female; Goats; Indometha | 1995 |
Possible role of platelet-activating factor in embryonic signaling during oviductal transport in the hamster.
Topics: Animals; Cricetinae; Culture Techniques; Diterpenes; Embryo, Mammalian; Female; Ginkgolides; Indomet | 1995 |
[Sulindac and indomethacin effects on lamb fetuses chronically monitored].
Topics: Animals; Female; Fetal Monitoring; Fetus; Indomethacin; Pregnancy; Sheep; Sulindac | 1994 |
Effects of captopril on the human foetal placental circulation: an interaction with bradykinin and angiotensin I.
Topics: Angiotensin I; Angiotensin II; Bradykinin; Captopril; Dose-Response Relationship, Drug; Drug Interac | 1995 |
Abnormal endothelial cell function of resistance arteries from women with preeclampsia.
Topics: Acetylcholine; Adult; Amino Acid Oxidoreductases; Arteries; Endothelium, Vascular; Female; Humans; I | 1993 |
Diabetes insipidus.
Topics: Benzothiadiazines; Carbamazepine; Chlorpropamide; Clofibrate; Diabetes Insipidus; Diuretics; Female; | 1994 |
The role of arachidonic acid and/or its metabolites in embryo implantation initiated by epidermal growth factor (EGF).
Topics: Animals; Arachidonic Acid; Dexamethasone; Dinoprostone; Embryo Implantation; Epidermal Growth Factor | 1995 |
Involvement of endothelin-1 in hypoxic pulmonary vasoconstriction in the lamb.
Topics: Animals; Arginine; Bradykinin; Endothelins; Endothelium; Female; Hypoxia; Indomethacin; NG-Nitroargi | 1995 |
Fetal echocardiography during indomethacin treatment.
Topics: Arterial Occlusive Diseases; Blood Flow Velocity; Constriction, Pathologic; Ductus Arteriosus; Echoc | 1995 |
Contractile effects of prostanoids on fetal rabbit ductus arteriosus.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Analysis of Variance; Animals; C | 1995 |
Prostaglandin E2 in cerebrospinal fluid of fetal and newborn sheep: central versus peripheral source.
Topics: Animals; Animals, Newborn; Blood Pressure; Blood-Brain Barrier; Dinoprostone; Female; Fetus; Heart R | 1994 |
The mechanism of relaxation in response to magnesium by the aorta of pregnant rats with salt-induced hypertension.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Endothelium, Vascular; Female; Hypertension; In Vitro Tech | 1995 |
Possible role and mechanism of inactivation of decidual NK cells in pregnancy.
Topics: Animals; Cytokines; Decidua; Female; Fetal Resorption; Gestational Age; Humans; Indomethacin; Killer | 1994 |
Long-term effects of prenatal indomethacin administration on the pulmonary circulation in rats.
Topics: Animals; Female; Hypertension, Pulmonary; Hypoxia; Indomethacin; Lung; Male; Pregnancy; Prenatal Exp | 1995 |
Effect of the vascular endothelium on noradrenaline-induced contractions in non-pregnant and pregnant guinea-pig uterine arteries.
Topics: Animals; Arginine; Arteries; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Guinea | 1995 |
Pressor effect of ethanol in the isolated perfused human placental lobule.
Topics: Blood Pressure; Ethanol; Female; Humans; In Vitro Techniques; Indomethacin; Perfusion; Placenta; Pla | 1994 |
Quadruplet pregnancy--successful outcome using indomethacin.
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Pregnancy Outcome; Pregnancy, M | 1994 |
Role of indomethacin-induced peptic ulceration in gastric acid secretion in pregnant rats.
Topics: Animals; Carbachol; Disease Models, Animal; Female; Gastric Acid; Histamine; Indomethacin; Peptic Ul | 1993 |
[Has the use of indomethacin during pregnancy consequences in newborn infants? Prospective study of 83 pregnant women and 115 newborn infants].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Obstetric Labor, Premature | 1994 |
Reversibility of tachyphylaxis to C5A in guinea pig tissues, perfused human placental lobule, and umbilical artery.
Topics: Animals; Complement C5a; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indomethacin; Lung | 1994 |
[A case of polyhydramnios treated with indomethacin under measurement of hourly fetal urine production rate (HFUPR) as an indicator].
Topics: Adult; Diagnosis, Differential; Diuresis; Female; Fetal Monitoring; Fetus; Humans; Indomethacin; Inf | 1994 |
Role of prostaglandin E2 and prostacyclin in nonshivering thermogenesis during simulated birth in utero.
Topics: 6-Ketoprostaglandin F1 alpha; Adenosine; Animals; Animals, Newborn; Blood Gas Analysis; Body Tempera | 1994 |
Properties of a progesterone-induced relaxation in human placental arteries and veins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Arginine; Arteries; Female; Humans; Indomethacin; Methylene Blu | 1995 |
Bacterial lipopolysaccharide-mediated fetal death. Production of a newly recognized form of inducible cyclooxygenase (COX-2) in murine decidua in response to lipopolysaccharide.
Topics: Abortion, Spontaneous; Animals; Bacterial Infections; Decidua; Dose-Response Relationship, Drug; Enz | 1995 |
Evidence for the essential role of prostaglandins for parturition in a marsupial, Macropus eugenii.
Topics: Animals; Bromocriptine; Dinoprost; Female; Fetus; Indomethacin; Labor, Obstetric; Macropodidae; Preg | 1994 |
Effect of phenazone (antipyrine) on the prostanoid formation in human umbilical arteries perfused in vitro.
Topics: Antipyrine; Arachidonic Acids; Female; Humans; In Vitro Techniques; Indomethacin; Pregnancy; Prostag | 1995 |
Properties of a lactate-induced relaxation in human placental arteries and veins.
Topics: Analysis of Variance; Arginine; Arteries; Colforsin; Cyanides; Dinoprost; Dose-Response Relationship | 1993 |
The contemporary use of beta-agonists.
Topics: Adrenergic beta-Agonists; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Tocol | 1994 |
The effect of indomethacin tocolysis on maternal coagulation status.
Topics: Administration, Oral; Adult; Bleeding Time; Blood Coagulation; Female; Humans; Indomethacin; Obstetr | 1994 |
Epidermal growth factor--induced implantation and decidualization in the rat.
Topics: Animals; Decidua; Dose-Response Relationship, Drug; Embryo Implantation, Delayed; Embryo, Mammalian; | 1994 |
Isolated small bowel perforation following intrauterine treatment with indomethacin.
Topics: Adult; Female; Fetal Diseases; Humans; Ileal Diseases; Indomethacin; Infant, Newborn; Intestinal Per | 1994 |
Endothelium-dependent relaxation of human resistance arteries in pregnancy.
Topics: Acetylcholine; Adult; Arginine; Arteries; Endothelium, Vascular; Female; Humans; Indomethacin; NG-Ni | 1994 |
Administration of human chorionic gonadotropin affects sleep-wake phases and other associated behaviors in cycling female rats.
Topics: Alprostadil; Animals; Behavior, Animal; Brain; Cerebral Cortex; Chorionic Gonadotropin; Estrus; Fema | 1994 |
Occurrence of endothelium-derived relaxing factor--nitric oxide in the lamb ductus arteriosus.
Topics: Animals; Arginine; Bradykinin; Ductus Arteriosus; Endothelium, Vascular; Female; Fetus; Indomethacin | 1994 |
Interactions between indomethacin, noradrenaline and vasodilators in the fetal rabbit ductus arteriosus.
Topics: Animals; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Ductus Arteriosus; Femal | 1994 |
Gene expression of pancreatic-type phospholipase-A2 in rat ovaries: stimulatory action on progesterone release.
Topics: Animals; Binding Sites; Corpus Luteum; Dinoprost; Dinoprostone; Female; Gene Expression; Indomethaci | 1994 |
The increase in vasomotor tone induced by a parenteral lipid emulsion is linked to an inhibition of prostacyclin production.
Topics: Cesarean Section; Dinoprost; Eicosanoids; Emulsions; Epoprostenol; Female; Humans; In Vitro Techniqu | 1994 |
Fatty acid modulation of epidermal growth factor-induced mouse mammary epithelial cell proliferation in vitro.
Topics: Animals; Arachidonic Acid; Cell Division; Cell Membrane; Drug Interactions; Enzyme Activation; Epide | 1994 |
Effects of prostaglandin inhibition on the renal function curve during ovine pregnancy.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Angiotensin II; Animals; Blood Pressure; Dinopro | 1994 |
Persistent anuria, neonatal death, and renal microcystic lesions after prenatal exposure to indomethacin.
Topics: Adult; Anuria; Dilatation, Pathologic; Female; Fetal Death; Humans; Immunohistochemistry; Indomethac | 1994 |
Paradoxical effect of inhaled nitric oxide in a newborn with pulmonary hypertension.
Topics: Administration, Inhalation; Diseases in Twins; Female; Humans; Hypoxia; Indomethacin; Infant, Newbor | 1993 |
Embryo implantation in the rat uterus induced by epidermal growth factor.
Topics: Animals; Embryo Implantation; Embryo Transfer; Epidermal Growth Factor; Estradiol; Female; Indometha | 1993 |
Successful pregnancy outcome in uterus didelphys with leiomyoma uteri.
Topics: Adult; Bed Rest; Cesarean Section; Female; Humans; Indomethacin; Leiomyoma; Obstetric Labor, Prematu | 1994 |
Indomethacin-induced maternal convulsion in the treatment of preterm labour.
Topics: Adult; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Pregnancy Complications; | 1993 |
[Influence of pregnancy on the vascular response to norepinephrine and serotonin in rat carotid artery].
Topics: Acetylcholine; Animals; Carotid Arteries; Female; In Vitro Techniques; Indomethacin; Norepinephrine; | 1994 |
Monoamine concentrations in cerebrospinal fluid of fetal and newborn sheep.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Biogenic Monoamines; Dinoprostone; | 1994 |
Efficacy and safety of indomethacin therapy for polyhydramnios.
Topics: Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Prostaglandins | 1993 |
Indomethacin tocolysis.
Topics: Ductus Arteriosus; Female; Humans; Indomethacin; Pregnancy; Tocolysis | 1994 |
Indomethacin as a tocolytic agent: the controversy continues.
Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Obstetric Labor, Prematu | 1994 |
Effect of interleukin 2 on the production of progesterone and prostaglandin E2 in human fetal membranes and its consequences for preterm uterine contractions.
Topics: Amniotic Fluid; Bacterial Infections; Chorioamnionitis; Culture Techniques; Dinoprostone; Extraembry | 1994 |
Inhibition of the fetal stress response improves cardiac output and gas exchange after fetal cardiac bypass.
Topics: Anesthesia, Spinal; Animals; Carbon Dioxide; Cardiac Output; Extracorporeal Circulation; Female; Fet | 1994 |
Chronic indomethacin administration and its relation with the renal kallikrein kinin system during rat pregnancy.
Topics: Animals; Creatinine; Female; Glomerular Filtration Rate; Indomethacin; Kallikrein-Kinin System; Kall | 1993 |
Renal impairment in very low birthweight infants following antenatal indomethacin administration.
Topics: Adult; Female; Humans; Indomethacin; Infant, Low Birth Weight; Infant, Newborn; Male; Maternal-Fetal | 1994 |
Neonatal complications after the administration of indomethacin for preterm labor.
Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Female; Fetus; Huma | 1993 |
Effect of prostaglandin E2 on rate of decidualization in rats.
Topics: Alkaline Phosphatase; Animals; Decidua; Dinoprostone; Drug Administration Schedule; Endometrium; Est | 1993 |
Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Bridged Bicyclo Compounds | 1993 |
Acute maternal renal insufficiency in premature labor treated with indomethacin.
Topics: Acute Kidney Injury; Administration, Oral; Adult; Dyspnea; Female; Fetofetal Transfusion; Humans; Hy | 1993 |
Delayed birth intervals of immature fraternal triplets in preterm labor. A case report.
Topics: Adult; Anti-Bacterial Agents; Birth Intervals; Birth Weight; Female; Gamete Intrafallopian Transfer; | 1993 |
Glucose, glycogen and triglyceride metabolism, as well as prostaglandin production in uterine strips and in embryos from diabetic pregnant rats. Influences of the presence of substrate in the incubation medium.
Topics: Alprostadil; Animals; Culture Techniques; Diabetes Mellitus, Experimental; Dinoprostone; Female; Fet | 1993 |
High-dose steroids prevent placental dysfunction after fetal cardiac bypass.
Topics: Animals; Bicarbonates; Blood Flow Velocity; Carbon Dioxide; Cardiac Output; Cardiopulmonary Bypass; | 1994 |
Effect of pregnancy on relaxation of rat aorta to magnesium.
Topics: Animals; Aorta, Thoracic; Calcium; Culture Techniques; Dose-Response Relationship, Drug; Endothelium | 1993 |
Tocolysis with indomethacin increases the incidence of necrotizing enterocolitis in the low-birth-weight neonate.
Topics: Birth Weight; Chi-Square Distribution; Cohort Studies; Enterocolitis, Pseudomembranous; Female; Gest | 1994 |
Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep.
Topics: Amniotic Fluid; Animals; Arginine Vasopressin; Blood Glucose; Body Fluids; Carbon Dioxide; Deglutiti | 1994 |
[Endothelin-1-induced contraction of pregnant rat myometrium: role of platelet-activating factor].
Topics: Animals; Dose-Response Relationship, Drug; Endothelins; Female; In Vitro Techniques; Indomethacin; I | 1994 |
Mechanism of pregnancy-induced attenuation of contraction to phenylephrine in rat aorta.
Topics: Acetylcholine; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Indo | 1993 |
Plasma from normal pregnant women alters the reactivity of rabbit aortic smooth muscle with functional endothelium.
Topics: Animals; Aorta; Calcium Chloride; Endothelium, Vascular; Female; Humans; In Vitro Techniques; Indome | 1993 |
Effect of prostaglandin synthesis inhibitors on spontaneous and endotoxin-induced abortion in mice.
Topics: Abortion, Spontaneous; Animals; Aspirin; Cyclooxygenase Inhibitors; Dinoprostone; Female; Indomethac | 1993 |
Mechanisms of vasodilatation in pregnancy: studies of the role of prostaglandins and nitric-oxide in changes of vascular reactivity in the in situ blood perfused mesentery of pregnant rats.
Topics: 6-Ketoprostaglandin F1 alpha; Angiotensin II; Animals; Arginine; Arginine Vasopressin; Blood Pressur | 1993 |
A rabbit model for ascending infection in pregnancy: intervention with indomethacin and delayed ampicillin-sulbactam therapy.
Topics: Ampicillin; Animals; Chorioamnionitis; Disease Models, Animal; Drug Therapy, Combination; Escherichi | 1993 |
The effect of gestational age and fetal indomethacin levels on the incidence of constriction of the fetal ductus arteriosus.
Topics: Blood Flow Velocity; Constriction, Pathologic; Diastole; Ductus Arteriosus; Female; Fetal Blood; Ges | 1993 |
[Maternal and neonatal effects of indomethacin administrated during pregnancy. Apropos of 18 cases].
Topics: Adult; Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Premature; Polyhydramni | 1993 |
Pregnancy in women with end-stage renal disease: treatment of anemia and premature labor.
Topics: Abnormalities, Drug-Induced; Adult; Anemia; Erythropoietin; Female; Hematocrit; Humans; Hypertension | 1993 |
Renal failure in two preterm infants: toxic effect of prenatal maternal indomethacin treatment?
Topics: Acute Kidney Injury; Adult; Amniocentesis; Cesarean Section; Female; Humans; Indomethacin; Infant, N | 1993 |
The influence of prostaglandins on the contractile response to electrical field stimulation in rabbit myometrial and cervical smooth muscles.
Topics: Animals; Cervix Uteri; Electric Stimulation; Female; In Vitro Techniques; Indomethacin; Myometrium; | 1993 |
Indomethacin in severe twin-to-twin transfusion syndrome.
Topics: Adult; Female; Fetal Death; Fetofetal Transfusion; Humans; Indomethacin; Infant Mortality; Infant, N | 1993 |
Exclusion of the placenta during fetal cardiac bypass augments systemic flow and provides important information about the mechanism of placental injury.
Topics: Animals; Blood Gas Analysis; Carbon Dioxide; Cardiac Output; Extracorporeal Circulation; Female; Fet | 1993 |
Arachidonic acid lipoxygenation may mediate interleukin-1 stimulation of nerve growth factor secretion in astroglial cultures.
Topics: Animals; Arachidonic Acid; Astrocytes; Calcium; Cerebral Cortex; Enzyme Activation; Enzyme-Linked Im | 1993 |
Interleukin-1 binding and prostaglandin E2 synthesis by amnion cells in culture: regulation by tumor necrosis factor-alpha, transforming growth factor-beta, and interleukin-1 receptor antagonist.
Topics: Amnion; Cells, Cultured; Cycloheximide; Dactinomycin; Dinoprostone; Female; Humans; Indomethacin; In | 1993 |
Endothelium-derived relaxing factor inhibits norepinephrine contraction of fetal guinea pig arteries.
Topics: Animals; Arginine; Arteries; Carotid Arteries; Endothelium, Vascular; Epithelium; Female; Fetus; Gui | 1993 |
Fetal pleural effusion following maternal indomethacin therapy.
Topics: Adult; Cesarean Section; Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Pleural Ef | 1993 |
Indomethacin use to control gross polyhydramnios complicating triplet pregnancy.
Topics: Adult; Cardiotocography; Cesarean Section; Dose-Response Relationship, Drug; Female; Fetal Monitorin | 1993 |
Withdrawal of placental prostaglandins permits thermogenic responses in fetal sheep brown adipose tissue.
Topics: Adipose Tissue; Amniotic Fluid; Animals; Blood Gas Analysis; Blood Pressure; Body Temperature Regula | 1993 |
Prostaglandin F2 alpha stimulates inositol phosphate production in human pregnant myometrium.
Topics: Calcium; Culture Techniques; Dinoprost; Female; Humans; Indomethacin; Inositol Phosphates; Myometriu | 1993 |
Effect of advancing gestational age on the frequency of fetal ductal constriction in association with maternal indomethacin use.
Topics: Constriction, Pathologic; Ductus Arteriosus; Echocardiography; Female; Fetal Diseases; Gestational A | 1993 |
Gestational diabetes alters human placental vascular responses to changes in oxygen tension.
Topics: Adolescent; Adult; Arteries; Cell Hypoxia; Diabetes, Gestational; Dose-Response Relationship, Drug; | 1993 |
Immunomodulation of cellular cytotoxicity to herpes simplex virus infection in pregnancy by inhibition of eicosanoid metabolism.
Topics: Animals; Cytotoxicity Tests, Immunologic; Cytotoxicity, Immunologic; Disease Models, Animal; Dose-Re | 1993 |
Good fetal outcome following prolonged indomethacin induced anhydramnios. Case report.
Topics: Adult; Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Oligohydramnios; P | 1995 |
The role of the vascular endothelium in the contractile responses of human chorionic plate artery in pre-eclampsia to prostaglandin F2 alpha, 5-hydroxytryptamine, and potassium chloride.
Topics: Arteries; Chorion; Dinoprost; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Human | 1995 |
Nitric oxide and prostaglandin systems inhibition on the isolated perfused human placenta from normal and preeclamptic pregnancies.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidotes; Arginine; Dose-Response Relationship, Drug; Fema | 1995 |
Effective treatment of drug-induced agranulocytosis using recombinant human granulocyte colony stimulating factor in pregnancy.
Topics: Adult; Agranulocytosis; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Hu | 1995 |
Role of prostaglandin I2 and prostaglandin E2 in the initiation of nonshivering thermogenesis during the simulation of birth in utero.
Topics: Animals; Body Temperature Regulation; Body Weight; Cold Temperature; Dinoprostone; Epoprostenol; Fat | 1995 |
Repeated administration of low-dose lipopolysaccharide induces preterm delivery in mice: a model for human preterm parturition and for assessment of the therapeutic ability of drugs against preterm delivery.
Topics: Animals; Disease Models, Animal; Escherichia coli; Female; Gabexate; Glycoproteins; Humans; Indometh | 1996 |
Adrenocorticotropin causes vasodilatation in the human fetal-placental circulation.
Topics: Adrenocorticotropic Hormone; Adult; Analysis of Variance; Blood Pressure; Dinoprost; Epoprostenol; F | 1996 |
Interaction between nitric oxide and prostaglandin E2 pathways in pregnant rat uteri.
Topics: Animals; Arginine; Dinoprostone; Enzyme Inhibitors; Female; Indomethacin; Interleukin-1; Labor, Obst | 1996 |
Doppler echocardiographic findings of indomethacin-induced occlusion of the fetal ductus arteriosus.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Cyclooxygenase Inhibitors; Dilatat | 1996 |
Acute renal failure in the neonate induced by the administration of indomethacin as a tocolytic agent.
Topics: Acute Kidney Injury; Adult; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn | 1996 |
Endothelial modulation of vascular tone and 5-hydroxytryptamine-induced responses in human chorionic arteries and veins.
Topics: Abortifacient Agents; Anti-Infective Agents, Urinary; Arginine; Arteries; Cyclooxygenase Inhibitors; | 1995 |
Effect of pregnancy on mechanisms of relaxation in human omental microvessels.
Topics: Acetylcholine; Adult; Arginine; Arterioles; Bradykinin; Drug Interactions; Enzyme Inhibitors; Female | 1996 |
Functional specialization in the ruminant placenta: evidence for two populations of fetal binucleate cells of different selective synthetic capacity.
Topics: Animals; Cell Nucleus; Female; Goats; Indomethacin; Leukocytes; Microscopy, Electron; Placenta; Preg | 1996 |
Mesenteric arterial function in the rat in pregnancy: role of sympathetic and sensory-motor perivascular nerves, endothelium, smooth muscle, nitric oxide and prostaglandins.
Topics: Acetylcholine; Animals; Arginine; Electric Stimulation; Endothelium, Vascular; Enzyme Inhibitors; Fe | 1996 |
Pharmacologic inhibition of particulate-induced bone resorption.
Topics: Analysis of Variance; Animals; Animals, Newborn; Bone Cements; Bone Resorption; Calcitonin; Calcium; | 1996 |
Effect of indomethacin on individual amniotic fluid indices in multiple gestations.
Topics: Amniotic Fluid; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Obstetric Labor, Premature; | 1996 |
Treatment of symptomatic polyhydramnios with indomethacin.
Topics: Adult; Evaluation Studies as Topic; Female; Humans; Indomethacin; Male; Polyhydramnios; Pregnancy; P | 1996 |
Angiolymphoid hyperplasia with eosinophilia: successful treatment with indomethacin farnesil.
Topics: Adult; Angiolymphoid Hyperplasia with Eosinophilia; Anti-Inflammatory Agents, Non-Steroidal; Female; | 1996 |
Comparison of nitric oxide and prostacyclin in endothelium-dependent vasorelaxation of human umbilical artery at midgestation.
Topics: Endothelium, Vascular; Epoprostenol; Female; Histamine; Humans; Indomethacin; Nitric Oxide; Nitric O | 1996 |
Study of post-natal effect of chemopreventive agents on ethylnitrosourea-induced transplacental carcinogenesis in rats. III. Inhibitory action of indomethacin, voltaren, theophylline and epsilon-aminocaproic acid.
Topics: Aminocaproic Acid; Animals; Anticarcinogenic Agents; Brain Neoplasms; Carcinogens; Central Nervous S | 1996 |
Preterm labour and delivery.
Topics: Adrenergic beta-Agonists; Biomarkers; Female; Humans; Indomethacin; Magnesium; Nitroglycerin; Obstet | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto | 1996 |
In utero congestive heart failure due to maternal indomethacin treatment for polyhydramnios and premature labour in a fetus with antenatal closure of the foramen ovale.
Topics: Adult; Autopsy; Female; Fetal Death; Heart Failure; Heart Septum; Humans; Indomethacin; Obstetric La | 1996 |
Investigation into the role of cyclooxygenase products in the bradykinin response on isolated human myometrium and umbilical artery.
Topics: Bradykinin; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Humans; In Vitro Te | 1996 |
Neurodevelopmental outcome of infants exposed to indomethacin antenatally.
Topics: Adult; Apgar Score; Birth Weight; Child Development; Contraindications; Female; Follow-Up Studies; G | 1996 |
Antenatal ultrasound diagnosis of dilated fetal bowel due to congenital chloride diarrhoea.
Topics: Adult; Chlorides; Diarrhea; Dilatation, Pathologic; Feces; Female; Humans; Indomethacin; Intestines; | 1996 |
Effect of dual tocolysis on the incidence of severe intraventricular hemorrhage among extremely low-birth-weight infants.
Topics: Cerebral Hemorrhage; Cerebral Ventricles; Drug Therapy, Combination; Female; Humans; Incidence; Indo | 1996 |
Successful planned delay of ovulation for one week with indomethacin.
Topics: Abortion, Habitual; Adult; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Infant, Newborn; | 1996 |
Nitric oxide contributes to estrogen-induced vasodilation of the ovine uterine circulation.
Topics: Animals; Cyclic GMP; Enzyme Inhibitors; Estradiol; Female; Hemodynamics; Indomethacin; NG-Nitroargin | 1996 |
Neonatal limb ischemia following maternal indomethacin treatment in twin pregnancies.
Topics: Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Ischemi | 1995 |
Effect of the vascular endothelium on contractions induced by prostaglandin F2 alpha in isolated pregnant guinea pig uterine artery.
Topics: Animals; Arteries; Cyclooxygenase Inhibitors; Dinoprost; Dose-Response Relationship, Drug; Endotheli | 1996 |
Drug induced closure of patent ductus arteriosus.
Topics: Cyclooxygenase Inhibitors; Ductus Arteriosus, Patent; Female; Fetal Diseases; Humans; Indomethacin; | 1996 |
Inhibitory effect of indomethacin on neonatal lung catabolism of prostaglandin E2: possible mechanism of the re-opening of the ductus arteriosus after indomethacin therapy.
Topics: Animals; Dinoprostone; Ductus Arteriosus, Patent; Female; Hydroxyprostaglandin Dehydrogenases; Indom | 1996 |
Preterm delivery after indomethacin. A risk factor for neonatal complications?
Topics: Cohort Studies; Ductus Arteriosus, Patent; Enterocolitis, Pseudomembranous; Female; Hemorrhage; Huma | 1996 |
Progesterone levels in preterm labor are not affected by ritodrin treatment.
Topics: Administration, Rectal; Female; Humans; Indomethacin; Infusion Pumps; Obstetric Labor, Premature; Pr | 1997 |
Doppler echocardiographic evaluation of ventricular diastolic filling in fetuses with ductal constriction.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Constriction, Pathologic; Ductus Arteriosus; Echocardiograp | 1997 |
Closure of the human fetal ductus arteriosus.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Ductus Arteriosus; Female; Glucocorticoids; Humans; Indomet | 1997 |
Association of gestational diabetes with abnormal maternal vascular endothelial function.
Topics: Acetylcholine; Arginine; Diabetes, Gestational; Endothelium, Vascular; Enzyme Inhibitors; Female; Hu | 1997 |
[Pregnancy complicated with symptomatic polyhydramnios: treatment with indomethacin].
Topics: Adult; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Prospective Studies; Tocolytic Agent | 1997 |
Bacterial lipopolysaccharide-mediated murine fetal death: the role of interleukin-1.
Topics: Animals; Antibodies; Dinoprostone; Female; Fetal Death; Indomethacin; Interleukin-1; Lipopolysacchar | 1997 |
Hysterotomy and selective delivery of an intrauterine dead fetus to prevent intrauterine death or brain damage of the surviving fetus in monochorionic twin pregnancy.
Topics: Adult; Delivery, Obstetric; Diseases in Twins; Female; Fetal Death; Gestational Age; Humans; Indomet | 1997 |
Congenital intractable diarrhea of infancy in Iraqi Jews.
Topics: Adrenal Glands; Arachidonic Acid; Child; Child, Preschool; Diarrhea, Infantile; Dinoprostone; Duoden | 1997 |
Low dose indomethacin via fetal vein or cerebral ventricle stimulates breathing movements in fetal sheep.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Fetus; Indomethacin; Movement; Pregnancy; Respiration; S | 1997 |
The course of the SAPHO syndrome during pregnancy.
Topics: Acne Vulgaris; Adult; Female; Humans; Hyperostosis; Indomethacin; Osteitis; Pregnancy; Pregnancy Com | 1996 |
Developmental dynamics of endothelial and neurogenic control of canine thoracic aorta.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Autonomic Nervous System; Dogs; Electric Stimulation; Endot | 1997 |
Antenatal indomethacin exposure and neonatal intraventricular hemorrhage: a side effect or an association?
Topics: Cerebral Hemorrhage; Female; Humans; Indomethacin; Infant, Newborn; Maternal-Fetal Exchange; Pregnan | 1997 |
Endothelium-derived relaxing factor as a mediator of bradykinin-induced perinatal pulmonary vasodilatation in fetal sheep.
Topics: Animals; Aorta, Thoracic; Bradykinin; Cyclooxygenase Inhibitors; Endothelium, Vascular; Epoprostenol | 1997 |
Interleukin-6 and its soluble receptor regulate the expression of insulin-like growth factor binding protein-5 in osteoblast cultures.
Topics: Animals; Antigens, CD; Blotting, Northern; Blotting, Western; Cells, Cultured; Cycloheximide; Dose-R | 1997 |
Characterization of macrophages isolated from the maternal surface of human term placenta by a new method of urokinase treatment.
Topics: Antigen-Presenting Cells; Cell Adhesion; Cell Separation; Centrifugation, Density Gradient; Female; | 1997 |
Isolated ductal closure in utero diagnosed by fetal echocardiography.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cardiomegaly; Choroid Plexus; Cysts; Ductus Arterios | 1997 |
Flow-mediated vasodilatation is enhanced in normal pregnancy but reduced in preeclampsia.
Topics: Adult; Arteries; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Female; Humans; Indomethacin; NG-Nitr | 1997 |
Roles of NO-synthase and cyclooxygenase in sex- and pregnancy-dependent arterial and venous pressures in the rat.
Topics: Acetylcholine; Animals; Arteries; Biological Factors; Blood Pressure; Cyclooxygenase Inhibitors; Enz | 1997 |
Perinatal regulation of the cerebral circulation: role of nitric oxide and prostaglandins.
Topics: Animals; Arginine; Blood Pressure; Brain; Carbon Dioxide; Carotid Arteries; Cerebrovascular Circulat | 1997 |
The effect of indomethacin tocolysis on fetal ductus arteriosus constriction with advancing gestational age.
Topics: Ductus Arteriosus; Echocardiography; Female; Gestational Age; Humans; Indomethacin; Obstetric Labor, | 1997 |
[Indomethacin in obstetrics: benefits and risks].
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Tocolytic Agents | 1997 |
Endogenous nitric oxide attenuates ethanol-induced vasoconstriction in the human placenta.
Topics: Antidotes; Endothelium, Vascular; Enzyme Inhibitors; Ethanol; Female; Humans; In Vitro Techniques; I | 1997 |
The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.
Topics: Animals; Animals, Newborn; Dinoprostone; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fetus | 1997 |
Indomethacin modifies the fetal hemodynamic response induced by percutaneous umbilical blood sampling.
Topics: 6-Ketoprostaglandin F1 alpha; Cordocentesis; Endothelin-1; Female; Fetal Blood; Gestational Age; Hea | 1997 |
Is there justification for using indomethacin in preterm labor? An analysis of neonatal risks and benefits.
Topics: Cerebral Hemorrhage; Decision Support Techniques; Enterocolitis, Pseudomembranous; Female; Gestation | 1997 |
Effects of simulated myocardial ischemic conditions on the responses of isolated human umbilical artery strips to 5-hydroxytryptamine and prostaglandin F2 alpha.
Topics: Culture Media; Cyclooxygenase Inhibitors; Dinoprost; Endothelins; Enzyme Inhibitors; Female; Humans; | 1997 |
Two-dimensional echocardiographic evaluation of ventricular systolic function in human fetuses with ductal constriction.
Topics: Blood Flow Velocity; Case-Control Studies; Constriction, Pathologic; Ductus Arteriosus; Echocardiogr | 1997 |
Evidence that nitric oxide is not the only mediator responsible for attenuated vascular responses during pregnancy.
Topics: Animals; Aorta, Abdominal; Aorta, Thoracic; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme | 1997 |
Indomethacin tocolysis.
Topics: Contraindications; Ductus Arteriosus, Patent; Echocardiography; Female; Gestational Age; Humans; Ind | 1998 |
Nitric oxide mediates platelet-activating factor stimulatory action on uterine prostaglandin production.
Topics: Animals; Arachidonic Acid; Citrulline; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; | 1998 |
Antenatal indomethacin--adverse fetal effects confirmed.
Topics: Cerebral Hemorrhage; Ductus Arteriosus, Patent; Female; Fetal Diseases; Humans; Indomethacin; Infant | 1998 |
The addition of indomethacin to betamimetics for tocolysis: any benefit for the neonate?
Topics: Adrenergic beta-Agonists; Bronchopulmonary Dysplasia; Cohort Studies; Female; Fetal Membranes, Prema | 1998 |
Safety of antenatal indomethacin.
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Risk Factors; Tocolysis | 1998 |
Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum.
Topics: Aminoquinolines; Animals; Aorta; Calcimycin; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme In | 1998 |
[Structure of the rat lymphoid organs after prenatal exposure to indomethacin during antigenic stimulation].
Topics: Animals; Antibody Formation; Drug Evaluation, Preclinical; Female; Immunization; Indomethacin; Lymph | 1998 |
Amniotic fluid prolactin is decreased by experimental intrauterine infection or interleukin-1beta infusion but not via prostaglandins in pregnant rhesus macaques.
Topics: Amnion; Amniotic Fluid; Animals; Chorioamnionitis; Chorion; Decidua; Female; Indomethacin; Interleuk | 1998 |
Effect of endothelium removal on prostaglandin and nitric oxide function in pulmonary resistance arteries in the lamb.
Topics: Animals; Bradykinin; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Fem | 1998 |
Toxic epidermal necrolysis associated with treatment for preterm labor.
Topics: Adult; Betamethasone; Female; Gestational Age; Glucocorticoids; Humans; Indomethacin; Obstetric Labo | 1998 |
Tocolytic effect of the cyclooxygenase-2 inhibitor, meloxicam: studies on uterine contractions in the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dose-Response Relations | 1998 |
Premature closure of the fetal ductus arteriosus after maternal use of non-steroidal anti-inflammatory drugs. Adverse Drug Reactions Advisory Committee.
Topics: Adverse Drug Reaction Reporting Systems; Anti-Inflammatory Agents, Non-Steroidal; Australia; Diclofe | 1998 |
Regulation of spontaneous rhythmic contractions in rat pregnant myometrium by corticotrophin-releasing factor.
Topics: Animals; Bucladesine; Corticotropin-Releasing Hormone; Cyclic AMP; Dose-Response Relationship, Drug; | 1998 |
Indomethacin tocolysis increases postnatal patent ductus arteriosus severity.
Topics: Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Infant, | 1998 |
Effect of nimesulide and indomethacin on contractility and the Ca2+ channel current in myometrial smooth muscle from pregnant women.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calcium Channel Blockers; Calcium Channels; Cyclooxygenase | 1998 |
Placental transfer of sulindac, sulindac sulfide, and indomethacin in a human placental perfusion model.
Topics: Chromatography, High Pressure Liquid; Female; Humans; In Vitro Techniques; Indomethacin; Perfusion; | 1999 |
Mechanisms of adrenomedullin-induced increase of pulmonary blood flow in fetal sheep.
Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor A | 1999 |
Streptozotocin diabetes in the pregnant rat induces cardiovascular dysfunction in adult offspring.
Topics: Acetylcholine; Animals; Blood Pressure; Bradykinin; Cardiovascular Diseases; Diabetes Mellitus, Expe | 1999 |
Prenatal and postnatal management of hyperprostaglandin E syndrome after genetic diagnosis from amniocytes.
Topics: Amniotic Fluid; Bartter Syndrome; DNA Mutational Analysis; Female; Humans; Indomethacin; Infant, New | 1999 |
ECT-induced premature labor: a case report.
Topics: Adult; Depressive Disorder; Electroconvulsive Therapy; Female; Humans; Indomethacin; Mental Disorder | 1999 |
The effects of maternal indomethacin therapy on human fetal branch pulmonary arterial vascular impedance.
Topics: Blood Flow Velocity; Cross-Sectional Studies; Ductus Arteriosus; Female; Fetus; Gestational Age; Hum | 1999 |
Developmental damage, increased lipid peroxidation, diminished cyclooxygenase-2 gene expression, and lowered prostaglandin E2 levels in rat embryos exposed to a diabetic environment.
Topics: Abnormalities, Drug-Induced; Animals; Congenital Abnormalities; Cyclooxygenase 1; Cyclooxygenase 2; | 1999 |
Bartter's syndrome and pregnancy.
Topics: Adult; Apgar Score; Cesarean Section; Creatinine; Diabetes, Gestational; Diuresis; Female; Humans; I | 1999 |
Bovine colostrum is a health food supplement which prevents NSAID induced gut damage.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Cell Culture Techniques; Cell Division; Ce | 1999 |
Lymphocyte subsets and mitogen stimulation of blood lymphocytes in preeclampsia.
Topics: Adult; Cells, Cultured; Cimetidine; Dexamethasone; Female; Flow Cytometry; Humans; Indomethacin; Int | 1999 |
The effect of indomethacin and prostacyclin agonists on blood pressure in a rat model of preeclampsia.
Topics: Animals; Blood Pressure; Cyclooxygenase Inhibitors; Disease Models, Animal; Enzyme Inhibitors; Epopr | 1999 |
PGE2 induces its own secretion in vitro by bovine 270-day placenta but not by 200-day placenta.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Aspartic Acid Endopeptidases; Biological Transport; Cat | 1999 |
Symptomatic hypocalcaemia in hypermagnesaemia-induced hypoparathyroidism, during magnesium tocolytic therapy--possible involvement of the calcium-sensing receptor.
Topics: Adult; Calcium; Female; Humans; Hypocalcemia; Hypoparathyroidism; Indomethacin; Magnesium; Nifedipin | 1999 |
Effects of nitroglycerin and indomethacin on fetal-maternal circulation and on fetal cerebral blood flow and metabolism in sheep.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Brain; Carotid Arteries; Female; Fetus; Heart Rate; He | 1999 |
Mechanisms of endothelium-dependent relaxation in myometrial resistance vessels and their alteration in preeclampsia.
Topics: Adult; Bradykinin; Cardiovascular Agents; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; | 1999 |
Effect of PGF2alpha, indomethacin, tamoxifen, or estradiol-17beta on incidence of abortion, progesterone, and pregnancy-specific protein B (PSPB) secretion in 88- to 90-day pregnant sheep.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Abortion, Veterinary; Animals; Aspartic Acid End | 1999 |
Effect of prostaglandin F2alpha (PGF2alpha), indomethacin, tamoxifen or estradiol-17beta on prostaglandin E (PGE), PGF2alpha and estradiol-17beta secretion in 88 to 90-day pregnant sheep.
Topics: Abortifacient Agents, Steroidal; Abortion, Induced; Abortion, Veterinary; Animals; Dinoprost; Estrad | 1999 |
Recent indomethacin tocolysis is not associated with neonatal complications in preterm infants.
Topics: Birth Weight; Case-Control Studies; Delivery, Obstetric; Drug Administration Schedule; Female; Gesta | 1999 |
Role of the nitric oxide-cGMP system in the regulation of ductus arteriosus patency in fetal rats.
Topics: Animals; Aorta, Thoracic; Cesarean Section; Cyclic GMP; Cyclooxygenase Inhibitors; Dose-Response Rel | 1999 |
Uncommon adverse maternal effects with indomethacin for tocolysis.
Topics: Adult; Drug Hypersensitivity; Dyspnea; Female; Humans; Indomethacin; Liver Function Tests; Pregnancy | 1999 |
Perinatal indomethacin treatment and neonatal complications in preterm infants.
Topics: Cerebral Hemorrhage; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newborn; Infa | 2000 |
A comparison of the effects of indomethacin and NS-398 (a selective prostaglandin H synthase-2 inhibitor) on implantation in the rat.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase | 1999 |
Effective diminution of amniotic prostaglandin production by selective inhibitors of cyclooxygenase type 2.
Topics: Amnion; Blotting, Western; Chorion; Cyclooxygenase Inhibitors; Decidua; Dinoprostone; Electrophoresi | 2000 |
Nitric oxide and prostaglandin interactions in the relaxant responses of rat aorta: influence of pregnancy.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Cyclooxygenase Inhibitors; Enzyme Inhib | 1999 |
Neuro-immuno-teratogenicity of drugs used in neonatal pharmacotherapy in relation to the ontogenic stage at the time of their administration.
Topics: Aging; Animals; Animals, Newborn; Antibody Formation; Brain; Dexamethasone; Female; Humans; Immunity | 1999 |
Alterations in relaxation to lactate and H(2)O(2) in human placental vessels from gestational diabetic pregnancies.
Topics: Adolescent; Adult; Arachidonic Acid; Colforsin; Diabetes, Gestational; Female; Humans; Hydrogen Pero | 2000 |
Pregnancy is associated with altered response to neuropeptide Y in uterine artery.
Topics: Acetylcholine; Animals; Arteries; Cyclooxygenase Inhibitors; Diethylcarbamazine; Enzyme Inhibitors; | 2000 |
Pregnancy does not alter the response of uterine arteries to vasoactive intestinal polypeptide.
Topics: Acetylcholine; Animals; Arteries; Cyclooxygenase Inhibitors; Diethylcarbamazine; Enzyme Inhibitors; | 2000 |
Polyhydramnios as a sign of fetal pseudohypoaldosteronism.
Topics: Adult; Amniocentesis; Cesarean Section; Female; Fetal Diseases; Follow-Up Studies; Gestational Age; | 2000 |
Endothelium and aortic contraction to endothelin-1 in the pregnant rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Blood Pressure; Body Weight; Endo | 2000 |
Inhibition of cyclooxygenase-2 prevents inflammation-mediated preterm labor in the mouse.
Topics: Animals; Blotting, Northern; Calcium; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2000 |
Cyclooxygenase-2 inhibitors constrict the fetal lamb ductus arteriosus both in vitro and in vivo.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase | 2000 |
Effects of TAK-044, a nonselective endothelin receptor antagonist, on the spontaneous and indomethacin- or methylene blue-induced constriction of the ductus arteriosus in rats.
Topics: Animals; Animals, Newborn; Cardiovascular Agents; Cesarean Section; Ductus Arteriosus; Endothelin Re | 2000 |
Indomethacin tocolysis and risk of necrotizing enterocolitis.
Topics: Adult; Case-Control Studies; Enterocolitis, Necrotizing; Female; Humans; Indomethacin; Infant, Newbo | 2000 |
Influence of oxytocin on prostaglandin E2, intracellular calcium, and cyclic adenosine monophosphate in human amnion-derived (WISH) cells.
Topics: Adenylyl Cyclases; Amnion; Calcium; Cell Line; Cyclic AMP; Dinoprostone; Enzyme Inhibitors; Estrenes | 2000 |
Cyclooxygenase is involved in the effects of progesterone-induced blocking factor on the production of interleukin 12.
Topics: Cyclooxygenase Inhibitors; Female; Humans; Immunohistochemistry; Indomethacin; Interleukin-12; Leuko | 2000 |
Indomethacin blocks interleukin 1beta-induced myometrial contractions in pregnant rhesus monkeys.
Topics: Amniotic Fluid; Animals; Cyclooxygenase Inhibitors; Dinoprost; Dinoprostone; Female; Indomethacin; I | 2000 |
Role of nitric oxide in regulating the ductus arteriosus caliber in fetal rats.
Topics: Animals; Cyclooxygenase Inhibitors; Ductus Arteriosus; Embryonic and Fetal Development; Enzyme Inhib | 2000 |
Subrenal aorta coarctation of pregnant rats: changes in vascular contractility.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Aortic Coarctation; Dose-Response | 2000 |
Melatonin suppresses lysophosphatidylcholine enhancement of serotonin-induced vasoconstriction in the human umbilical artery.
Topics: Adult; Dose-Response Relationship, Drug; Drug Synergism; Female; Free Radical Scavengers; Humans; In | 2000 |
Search for best tocolytic for preterm labour.
Topics: Female; Humans; Indomethacin; Nifedipine; Obstetric Labor, Premature; Pregnancy; Randomized Controll | 2000 |
Biphasic response of the ductus arteriosus to combined administration of indomethacin and L-NAME in fetal rats.
Topics: Animals; Cyclooxygenase Inhibitors; Ductus Arteriosus; Enzyme Inhibitors; Female; Guanylate Cyclase; | 2000 |
Vascular reactivity to angiotensin II and eicosanoid production in the human placenta from term and preterm pregnancy.
Topics: 6-Ketoprostaglandin F1 alpha; Analysis of Variance; Angiotensin II; Culture Techniques; Enzyme-Linke | 2000 |
Function of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the ductus arteriosus from foetal lamb: differential development and change by oxygen and endotoxin.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2001 |
Effects of indomethacin, NS-398 (a selective prostaglandin H synthase-2 inhibitor) and protein synthesis inhibitors on prostaglandin production by the guinea-pig placenta.
Topics: Animals; Cell Culture Techniques; Cyclooxygenase Inhibitors; Female; Guinea Pigs; Indomethacin; Isoe | 2001 |
Indomethacin activity in the fetal vasculature of normal and meconium exposed human placentae.
Topics: Amniotic Fluid; Arteries; Female; Fetus; Humans; In Vitro Techniques; Indomethacin; Meconium; Placen | 2001 |
Effect of lipopolysaccharide on uterine contractions and prostaglandin production in pregnant rats.
Topics: Amniotic Fluid; Animals; Dinoprost; Dinoprostone; Endotoxins; Female; Indomethacin; Injections, Intr | 2001 |
Enhancement of amniotic cyclooxygenase type 2 activity in women with preterm delivery associated with twins or polyhydramnios.
Topics: Amnion; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; | 2001 |
Renal tubular dysgenesis-like lesions and hypocalvaria. Report of two cases involving indomethacin.
Topics: Adult; E2F6 Transcription Factor; Fatal Outcome; Female; Fetofetal Transfusion; Gestational Age; Hum | 2000 |
Radiofrequency ablation of human fetal sacrococcygeal teratoma.
Topics: Adult; Catheter Ablation; Electrocardiography; Fatal Outcome; Female; Fetal Diseases; Humans; Indome | 2001 |
Can a cyclo-oxygenase type-2 selective tocolytic agent avoid the fetal side effects of indomethacin?
Topics: Administration, Oral; Adult; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitor | 2001 |
Endothelium dependence and gestational regulation of inhibition of vascular tone by magnesium sulfate in rat aorta.
Topics: Aminoquinolines; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cyclic GMP; Cyclooxygenase Inhi | 2001 |
Effects of indomethacin, luteinizing hormone (LH), prostaglandin E2 (PGE2), trilostane, mifepristone, ethamoxytriphetol (MER-25) on secretion of prostaglandin E (PGE), prostaglandin F2alpha (PGF2alpha) and progesterone by ovine corpora lutea of pregnancy
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Cyclooxygenase Inhibitors; Dihydrotestoster | 2001 |
Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants.
Topics: Adult; Cell Hypoxia; Chorionic Villi; Culture Techniques; Cyclooxygenase Inhibitors; Cytokines; Drug | 2001 |
Progressive lung and cardiac changes associated with pulmonary hypertension in the fetal rat.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Female; Fetal Heart; Hypertension, Pulmonary; | 2001 |
Mechanisms of endothelin-1-induced contraction in isolated placental veins from normal full-term and preterm pregnancies.
Topics: Endothelin Receptor Antagonists; Endothelin-1; Female; Gestational Age; Humans; Indomethacin; Infant | 2000 |
Indomethacin tocolysis and intraventricular hemorrhage.
Topics: Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Case-Control Studies; Confiden | 2001 |
The effect of vitamin A on contraction of the ductus arteriosus in fetal rat.
Topics: Animals; Calcium; Ductus Arteriosus; Endothelium, Vascular; Female; Fetus; Indomethacin; Maternal-Fe | 2001 |
Rat as model for studying behavior effects of hCG.
Topics: Animals; Anxiety; Behavior, Animal; Chorionic Gonadotropin; Electroencephalography; Electromyography | 2001 |
Neonatal acute haemorrhagic gastritis and antenatal exposure to indomethacin for tocolysis.
Topics: Adolescent; Fatal Outcome; Female; Gastric Mucosa; Gastritis; Gastrointestinal Hemorrhage; Humans; I | 2001 |
Effect of maternal tocolysis on the incidence of severe periventricular/intraventricular haemorrhage in very low birthweight infants.
Topics: Anti-Inflammatory Agents; Apgar Score; Ductus Arteriosus, Patent; Female; Gestational Age; Humans; I | 2001 |
Melatonin inhibits spontaneous and oxytocin-induced contractions of rat myometrium in vitro.
Topics: Animals; Apamin; Calcium; Cyclooxygenase Inhibitors; Dinoprost; Female; In Vitro Techniques; Indomet | 2001 |
Inhibitor effect of omeprazole in isolated human myometrial smooth muscle.
Topics: Calcium; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; I | 2001 |
Inhibition of cyclooxygenase but not nitric oxide synthase influences effects on the human omental artery of the thromboxane A2 mimetic U46619 and 17beta-estradiol.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Cyclooxygenase | 2001 |
[Compensatory responses in lymph nodes following by prenatal indomethacin exposure].
Topics: Adaptation, Physiological; Animals; Female; Indomethacin; Luminescent Measurements; Lymph Nodes; Pre | 2001 |
The effects of cervical application of inhibitors of inducible nitric oxide synthase, cyclooxygenase-1, and cyclooxygenase-2 on delivery in rats.
Topics: Administration, Topical; Animals; Cervical Ripening; Cervix Uteri; Cyclooxygenase Inhibitors; Delive | 2001 |
Meloxicam inhibits rabbit ovulation.
Topics: Animals; Cyclooxygenase Inhibitors; Female; Indomethacin; Meloxicam; Ovary; Ovulation; Pregnancy; Ra | 2001 |
Tricuspid regurgitation in a pair of twins at birth secondary to antenatal indomethacin.
Topics: Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Polyhydramnios; Pregnancy; Tocolyti | 2001 |
Matrix metalloproteinase (MMP)-2 and MMP-9 and their inhibitor, TIMP-1, in human term decidua and fetal membranes: the effect of prostaglandin F(2alpha) and indomethacin.
Topics: Cesarean Section; Cyclooxygenase Inhibitors; Decidua; Dinoprost; Extraembryonic Membranes; Female; H | 2001 |
Preventive management of hypoglycemia in very low-birthweight infants following indomethacin therapy for patent ductus arteriosus.
Topics: Blood Glucose; Ductus Arteriosus, Patent; Female; Gestational Age; Glucose; Humans; Hypoglycemia; In | 2001 |
In utero indomethacin alters O2 delivery to the fetal ductus arteriosus: implications for postnatal patency.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Death; Ductus Arteriosus; Ductus Arteriosus, | 2002 |
Reversible fetal hydrops associated with indomethacin use.
Topics: Adult; Ductus Arteriosus; Female; Humans; Hydrops Fetalis; Indomethacin; Pregnancy; Time Factors; To | 1997 |
Indomethacin therapy in the treatment of polyhydramnios due to placental chorioangioma.
Topics: Adult; Female; Hemangioma; Humans; Indomethacin; Placenta Diseases; Polyhydramnios; Pregnancy; Pregn | 2001 |
Indomethacin blocks pre-partum nest building behaviour in the pig (Sus scrofa): effects on plasma prostaglandin F metabolite, oxytocin, cortisol and progesterone.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprost; Female; Hydrocortisone; Indomethacin; Injections, Int | 2002 |
Placentally derived prostaglandin E2 acts via the EP4 receptor to inhibit IL-2-dependent proliferation of CTLL-2 T cells.
Topics: Animals; Benzene Derivatives; Cell Division; Chorionic Villi; Cyclooxygenase 2; Cyclooxygenase 2 Inh | 2002 |
Severe heart failure due to ductal constriction caused by maternal indomethacin.
Topics: Adult; Constriction, Pathologic; Ductus Arteriosus; Female; Heart Failure; Humans; Indomethacin; Inf | 2002 |
Vasodilation to vascular endothelial growth factor in the uterine artery of the pregnant rat is blunted by low dietary protein intake.
Topics: Acetylcholine; Animals; Arteries; Body Weight; Cardiovascular Agents; Caseins; Dietary Proteins; Dos | 2002 |
[Tocolysis and its place in premature labor].
Topics: Adrenergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Bulgaria; Drug Interactions; Female; Hum | 1999 |
The hyperaggregability of platelets from normal pregnancy is mediated through thromboxane A2 and cyclic AMP pathways.
Topics: Adult; Alprostadil; Calcium Signaling; Cyclic AMP; Disease Susceptibility; Female; Humans; Hydrogen- | 2002 |
Site and mechanism of action of dynorphin A-(1-13) and N-methyl-D-aspartate on ACTH release in fetal sheep.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Adrenocort | 2002 |
Anti-implantation effects of indomethacin and celecoxib in rats.
Topics: Animals; Celecoxib; Contraception; Contraceptives, Postcoital; Cyclooxygenase Inhibitors; Decidua; E | 2002 |
Indomethacin-induced rectovaginal fistula in a postpartum patient.
Topics: Adult; Colostomy; Escherichia coli Infections; Fecal Incontinence; Female; Humans; Indomethacin; Obs | 2002 |
Clearance and disposition of indometacin in chronically instrumented fetal lambs following a 3-day continuous intravenous infusion.
Topics: Animals; Animals, Newborn; Dose-Response Relationship, Drug; Female; Fetus; Indomethacin; Infusions, | 2002 |
[Prevention of premature labor].
Topics: Adrenergic beta-Agonists; Aspirin; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnan | 1975 |
Further evidence implicating E-type prostaglandins in the patency of the lamb ductus arteriosus.
Topics: Animals; Animals, Newborn; Carbon Dioxide; Ductus Arteriosus; Female; Hydrogen-Ion Concentration; In | 1975 |
The effect of indomethacin in labour at term.
Topics: Adult; Female; Humans; Indomethacin; Labor, Obstetric; Pregnancy; Prostaglandin Antagonists; Time Fa | 1976 |
Indomethacin in low concentration potentiates the actions of some spasmogens on the isolated oestrous rat uterus.
Topics: Acetylcholine; Animals; Bradykinin; Drug Synergism; Estrus; Female; In Vitro Techniques; Indomethaci | 1977 |
Activation of guanylate cyclase by arachidonic acid in mammary gland homogenates from mice.
Topics: Animals; Arachidonic Acids; Enzyme Activation; Fatty Acids; Female; Guanylate Cyclase; In Vitro Tech | 1978 |
Responses of pulmonary and systemic circulations of perinatal goats to prostaglandin F2 alpha.
Topics: Aging; Animals; Animals, Newborn; Blood Circulation; Blood Gas Analysis; Female; Fetus; Goats; Hydro | 1979 |
Letter: Indomethacin and closure of the ductus arteriosus.
Topics: Animals; Ductus Arteriosus; Ductus Arteriosus, Patent; Edema; Female; Humans; In Vitro Techniques; I | 1975 |
Perinatal use of indomethacin.
Topics: Animals; Female; Fetal Death; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Rats | 1977 |
Post-partum pulmonary oedema associated with preventive therapy for premature labour.
Topics: Adult; Betamethasone; Drug Therapy, Combination; Female; Humans; Indomethacin; Obstetric Labor, Prem | 1979 |
Effect on the fetus of indomethacin given to suppress labour.
Topics: Animals; Female; Fetal Heart; Humans; Indomethacin; Infant, Newborn; Male; Maternal-Fetal Exchange; | 1979 |
Modification of vascular responsiveness to angiotensin II in pregnant women by intravenously infused 5alpha-dihydroprogesterone.
Topics: 20-alpha-Dihydroprogesterone; Angiotensin II; Cyclooxygenase Inhibitors; Drug Resistance; Female; Hu | 1978 |
Prostaglandins and regulation of the pulmonary circulation in the perinatal period.
Topics: Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Female; Fetus; Goats; Indomethacin; Pregnancy | 1977 |
Treatment of premature labor by prostaglandin synthetase inhibitors.
Topics: Adult; Animals; Anti-Inflammatory Agents; Birth Weight; Cyclooxygenase Inhibitors; Female; Gestation | 1978 |
Premature onset of labor, neonatal patent ductus arteriosus, and prostaglandin synthetase antagonists--a rat model of a human problem.
Topics: Animals; Brain Diseases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Ductus Arterio | 1979 |
Effect of prostaglandin synthetase inhibitors on pressor response to angiotensin II in human pregnancy.
Topics: Angiotensin II; Aspirin; Blood Pressure; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; In | 1978 |
Estrogen-directed synthesis of specific prostaglandins in uterus.
Topics: Animals; Castration; Cyclic AMP; Cyclic GMP; Diestrus; Estradiol; Estrogens; Estrus; Female; Indomet | 1975 |
Human placental cAMP phosphodiesterase activity kinetic properties and sensitivity to some drugs and hormones.
Topics: Caffeine; Cyclic AMP; Epinephrine; Estradiol; Female; Flufenamic Acid; Hormones; Humans; Imidazoles; | 1975 |
Effects of arachidonic acid on RNA metabolism in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Breast; Bucladesine; Cyclic GMP; Female; Indomethacin; Linoleic Acids; M | 1975 |
[Prostaglandins and reproduction].
Topics: Animals; Aspirin; Corpus Luteum; Cricetinae; Cyclic AMP; Female; Gonadotropin-Releasing Hormone; Hum | 1975 |
Phospholipases and the effect of prolactin on uridine incorporation into RNA in mammary gland explants of mice.
Topics: Animals; Arachidonic Acids; Bucladesine; Cyclic GMP; Female; Indomethacin; Mammary Glands, Animal; O | 1976 |
The regulatory role of steroid hormones on the PGF/PGE ratio in target tissues.
Topics: Animals; Castration; Cyclic AMP; Cyclic GMP; Estradiol; Estrogens; Estrus; Female; Guinea Pigs; Indo | 1976 |
Direct stimulation of bone resorption by thyroid hormones.
Topics: Animals; Bone and Bones; Bone Resorption; Cyclic AMP; Dose-Response Relationship, Drug; Female; Indo | 1976 |
Effect of Indomethacin on cyclic AMP phosphodiesterase activity in myometrium from pregnant rhesus monkeys.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Caffeine; Drug Synergism; Epinephrine; Female; Haplorh | 1976 |
[3'5'-Cyclic AMP phosphodiesterase activity in the internal and external layers of human myometrium at the end of pregnancy].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Caffeine; Female; Humans; Imidazoles; Indomethacin; Kinetics; M | 1977 |
Endocrine and pharmacological factors which influence the onset of labour in rhesus monkeys.
Topics: Adrenocorticotropic Hormone; Anencephaly; Animals; Endocrine Glands; Estrogens; Female; Fetus; Haplo | 1977 |
Uterine prostaglandin levels following stimulation of the decidual cell reaction: effects of indomethacin and tranylcypromine.
Topics: Animals; Castration; Cyclic AMP; Decidua; Estradiol; Female; Indomethacin; Mice; Organ Size; Pregnan | 1979 |
The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Drug Therapy, Combina | 1975 |
Pharmacologic control of uterine contractility. In vitro human and in vivo monkey studies.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Female; Fenoprofen; Fetu | 1975 |
Antiluteolytic effect of the embryo.
Topics: Abortion, Spontaneous; Animals; Corpus Luteum; Embryo, Mammalian; Estradiol; Female; Guinea Pigs; In | 1978 |
[Problems of rheumatism therapy in pregnant women].
Topics: Abortion, Spontaneous; Chloroquine; Female; Gold; Humans; Hyperbilirubinemia; Indomethacin; Penicill | 1978 |
The effect of aprotinin on luteolysis and uterine motility in late pregnancy and parturition in rats.
Topics: Animals; Aprotinin; Corpus Luteum; Female; Indomethacin; Placenta; Pregnancy; Pregnancy, Animal; Rat | 1978 |
Prostaglandin I2 is less relaxant than prostaglandin E2 on the lamb ductus arteriosus.
Topics: Animals; Culture Media; Ductus Arteriosus; Epoprostenol; Female; Indomethacin; Muscle, Smooth; Oxyge | 1978 |
Endotoxin-induced interruption of early pregnancy in the rabbit.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Endotoxins; Female; Indomethacin; | 1978 |
Pathophysiologic considerations in peptic ulcer disease.
Topics: ABO Blood-Group System; Adrenal Cortex Hormones; Aspirin; Bicarbonates; Environment; Female; Gastric | 1979 |
Prostaglandins and the release of LHRH from hypothalamic synaptosomes. Effects of indomethacin pretreatment.
Topics: Animals; Diestrus; Female; Gonadotropin-Releasing Hormone; Hypothalamus; In Vitro Techniques; Indome | 1979 |
Dual actions of prostacyclin (PGI2) on the rat pregnant uterus.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Epoprostenol; Female; In Vitro Techniques | 1979 |
The effect of angiotensin II and indomethacin on uterine artery blood flow in pregnant monkeys.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Curare; Depression, Chemical; Female; Haplorhini; | 1977 |
Pharmacology of the ductus arteriosus.
Topics: Aspirin; Chloroquine; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Patent; Femal | 1978 |
Morphologic analysis of the pulmonary vascular bed in infants exposed in utero to prostaglandin synthetase inhibitors.
Topics: Adult; Blood Vessels; Cyclooxygenase Inhibitors; Ductus Arteriosus; Female; Fetus; Humans; Indometha | 1978 |
Pulmonary vascular responses to prostaglandins and prostaglandin synthetase inhibitors in perinatal goats.
Topics: Animals; Animals, Newborn; Blood Pressure; Cyclooxygenase Inhibitors; Female; Fetus; Hemodynamics; I | 1978 |
Effects of indomethacin on labor, fetal oxygenation, and fetal development in rhesus monkeys.
Topics: Amniotic Fluid; Animals; Female; Fetus; Gestational Age; Haplorhini; Indomethacin; Labor, Obstetric; | 1978 |
Alcohol, indomethacin, and salbutamol. A comparative trial of their use in preterm labor.
Topics: Albuterol; Birth Weight; Drug Therapy, Combination; Ethanol; Female; Fetal Membranes, Premature Rupt | 1979 |
The effect of indomethacin on the instillation-abortion interval in rivanol-induced mid-trimester abortion.
Topics: Abortion, Induced; Acridines; Ethacridine; Female; Humans; Indomethacin; Pregnancy; Pregnancy Trimes | 1979 |
Constriction of the fetal ductus arteriosus after administration of indomethacin to the pregnant ewe.
Topics: Animals; Blood Pressure; Ductus Arteriosus; Female; Fetal Diseases; Hypertension, Pulmonary; Indomet | 1979 |
[Effects of flurbiprofen and indomethacin on release of prostaglandin F 2 alpha from uterus and plasma levels of sex hormones during parturition in rats (author's transl)].
Topics: Animals; Corpus Luteum; Female; Flurbiprofen; Gonadal Steroid Hormones; In Vitro Techniques; Indomet | 1979 |
Ovine placental vascular responses to indomethacin.
Topics: Animals; Blood Pressure; Extraembryonic Membranes; Female; Fetus; Indomethacin; Kidney; Placenta; Pr | 1979 |
[Studies on the mechanism of the effect of adenosine on the contractility of blood vessels on human placenta].
Topics: Adenosine; Adenosine Triphosphate; Drug Antagonism; Female; Humans; Indomethacin; Muscle Contraction | 1979 |
Prostaglandin control of the renal circulation in response to hypoxemia in the fetal lamb in utero.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Bradycardia; Female; Fetal Hypoxia; Fetus; Heart Rate; | 1979 |
Relaxin concentrations in pig plasma after the administration of indomethacin and prostaglandin F2 alpha during late pregnancy.
Topics: Animals; Female; Indomethacin; Male; Pregnancy; Pregnancy, Animal; Prostaglandins F; Relaxin; Swine; | 1979 |
Role of prostaglandin production in spontaneous and oxytocin-induced uterine contractile activity in in vitro pregnant rat uteri.
Topics: Animals; Female; In Vitro Techniques; Indomethacin; Oxytocin; Pregnancy; Prostaglandins E; Prostagla | 1979 |
Prostaglandins and increased endometrial vascular permeabiltiy resulting from the application of artificial stimulus to the uterus of the rat sensitized for the decidual cell reaction.
Topics: Animals; Capillary Permeability; Decidua; Endometrium; Female; Indomethacin; Pregnancy; Prostaglandi | 1979 |
Pulmonary-aortic pressure gradients as index of caliber of fetal patent ductus arteriosus.
Topics: Animals; Aorta; Blood Pressure Determination; Ductus Arteriosus; Female; Fetal Heart; Indomethacin; | 1979 |
Vascular responsiveness to pressor agents during human pregnancy.
Topics: Aldosterone; Angiotensin II; Aspirin; Female; Hematocrit; Humans; Hypertension; Indomethacin; Pregna | 1979 |
Prostaglandins in the pathogenesis of the generalized Shwartzman reaction.
Topics: Animals; Aspirin; Bradykinin; Cortisone; Endotoxins; Female; Indomethacin; Male; Pregnancy; Prostagl | 1979 |
Serum growth hormone, somatomedin and its carrier protein in the rat: influence of age, sex, and pregnancy.
Topics: Age Factors; Animals; Body Weight; Carrier Proteins; Female; Fetal Blood; Fetus; Growth Hormone; Gro | 1979 |
Perinatal hazards of chronic antenatal tocolysis with indomethacin.
Topics: Adult; Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature, Diseases; Obstetric Labor, | 1979 |
Indomethacin and uterine evacuation of conceptus in rats: possible mode of action.
Topics: Animals; Female; Gestational Age; Indomethacin; Myometrium; Pregnancy; Prostaglandins F; Pseudopregn | 1979 |
Inhibition of ovulation and fertilization by indomethacin and effect of prostaglandin-F2 alpha on early pregnancy in the rabbit.
Topics: Animals; Corpus Luteum; Female; Fertilization; Gestational Age; Indomethacin; Ovulation; Pregnancy; | 1979 |
Effect of indomethacin on luteal function in ewes and heifers.
Topics: Animals; Cattle; Corpus Luteum; Estrus; Female; Indomethacin; Injections; Luteolysis; Pregnancy; Pro | 1977 |
Blockers of prostaglandin synthesis: a novel therapy in the management of the premature human infant with patent ductus arteriosus.
Topics: Animals; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fetus; Humans; Indomethacin; Infant, | 1978 |
[Factors of motoricity of the ductus arteriosus].
Topics: Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Pregnan | 1978 |
Is the spontaneous motility of isolated rat uterus controlled by prostaglandin E?
Topics: Animals; Estrus; Female; Indomethacin; Ovary; Pregnancy; Prostaglandins E; Prostaglandins F; Rats; S | 1979 |
The effects of indomethacin on plasma LH levels in female and male deermice (Peromyscus maniculatus).
Topics: Animals; Castration; Estrus; Female; Indomethacin; Luteinizing Hormone; Male; Mice; Peromyscus; Preg | 1979 |
The metabolism of prostaglandin E2 by tissues from the human uterus and foeto-placental unit.
Topics: Arachidonic Acids; Decidua; Endometrium; Extraembryonic Membranes; Female; Humans; Indomethacin; Lab | 1978 |
PDAs, prostaglandins, and RLF.
Topics: Aspirin; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; Pregnancy; Prosta | 1978 |
Differences in the effects of vasopressin and oxytocin on rabbit myometrial activity and a possible mediation of prostaglandins.
Topics: Animals; Blood Pressure; Female; Indomethacin; Myometrium; Oxytocin; Pregnancy; Prostaglandins E; Pr | 1977 |
The effect of indomethacin on spontaneous activity in the isolated human myometrium and on the response to oxytocin and prostaglandin.
Topics: Drug Interactions; Female; Humans; In Vitro Techniques; Indomethacin; Oxytocin; Pregnancy; Prostagla | 1978 |
Antifertility effects of indomethacin during early pregnancy in the rabbit.
Topics: Animals; Decidua; Estradiol; Female; Fetus; Follicle Stimulating Hormone; Indomethacin; Luteinizing | 1978 |
Estrogen and female fertility. II. Indomethacin and the reversal of the luteolytic efficacy of estradiol cyclopentylpropionate.
Topics: Animals; Cyclopentanes; Estradiol; Female; Indomethacin; Luteolysis; Pregnancy; Pregnancy Maintenanc | 1978 |
Relationship of maternal treatment with indomethacin to persistence of fetal circulation syndrome.
Topics: Ductus Arteriosus, Patent; Female; Fetus; Humans; Indomethacin; Infant, Newborn; Obstetric Labor Com | 1978 |
Significance of the prostaglandin system to the control of muscle tone of the ductus arteriosus.
Topics: Animals; Animals, Newborn; Arachidonic Acids; Ductus Arteriosus; Female; Fetus; Glutathione; Indomet | 1978 |
Pregnant mare's serum gonadotropin. IV. Induction of premature labor by pregnant mare's serum gonadotropin and its prevention by using clomiphene or indomethacin.
Topics: Abortifacient Agents; Animals; Clomiphene; Female; Gonadotropins, Equine; Indomethacin; Labor, Induc | 1978 |
[Contraceptive effect of methylglucamine and indomethacin in the female rabbit].
Topics: Animals; Female; Indomethacin; Injections, Intramuscular; Meglumine; Ovary; Ovulation; Pregnancy; Pr | 1978 |
Indomethacin is a placental vasodilator in the dog. The effect of prostaglandin inhibition.
Topics: Amniotic Fluid; Animals; Dogs; Female; Hemodynamics; Indomethacin; Placenta; Pregnancy; Pressure; Pr | 1978 |
The effect of several vasoactive drugs on ovarian blood flow in the near-term sheep.
Topics: Angiotensin II; Animals; Female; Gestational Age; Indomethacin; Microspheres; Norepinephrine; Ovary; | 1978 |
Effect of angiotensin II on ovine placental blood flow.
Topics: Angiotensin II; Animals; Drug Interactions; Female; Gestational Age; Indomethacin; Kidney; Placenta; | 1978 |
Isolation of two proteins with 9-ketoprostaglandin reductase and NADP-linked 15-hydroxyprostaglandin dehydrogenase activities and studies on their inhibition.
Topics: Ethacrynic Acid; Female; Furosemide; Humans; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Plac | 1978 |
Management of premature labor.
Topics: Aspirin; Bed Rest; Betamethasone; Estrogens; Ethanol; Female; Fetal Membranes, Premature Rupture; Gl | 1978 |
Influence of adenosine on contractility of isolated vessels of human placenta.
Topics: Adenosine; Blood Vessels; Dopamine; Female; Humans; Indomethacin; Norepinephrine; Placenta; Pregnanc | 1978 |
The effects of hypoxia and indomethacin on the responsiveness of fetal and neonatal mesenteric arteries to epinephrine.
Topics: Animals; Animals, Newborn; Blood Vessels; Epinephrine; Female; In Vitro Techniques; Indomethacin; Me | 1978 |
Effects of indomethacin on uterine capillary permeability and blastocyst development in rabbits.
Topics: Animals; Blastocyst; Capillary Permeability; Female; Gestational Age; Indomethacin; Ovary; Pregnancy | 1978 |
Effects of indomethacin on sheep uteroplacental circulations and sensitivity to angiotensin II.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Fetus; Indomethacin; Placenta; Pregnancy; Pregnancy | 1978 |
The effect of prostaglandin E(2) and indomethacin on the placental vascular response to norepinephrine.
Topics: Animals; Drug Interactions; Female; Indomethacin; Norepinephrine; Placenta; Pregnancy; Prostaglandin | 1978 |
Developmental responses to oxygen, arachidonic acid, and indomethacin in the fetal lamb ductus arteriosus in vitro.
Topics: Animals; Arachidonic Acids; Ductus Arteriosus; Female; Gestational Age; In Vitro Techniques; Indomet | 1978 |
Pregnant mare's serum gonadotropin: V. Indomethacin or cortisone and the reversal of antifertility efficacy of pregnant mare's serum gonadotropin.
Topics: Animals; Corpus Luteum; Cortisone; Female; Fertility; Fetus; Gonadotropins; Gonadotropins, Equine; H | 1978 |
The importance of prostaglandin synthesis for the initiation of blastocyst implantation in the hamster.
Topics: Animals; Blastocyst; Castration; Cricetinae; Embryo Implantation; Endometrium; Evans Blue; Female; I | 1978 |
Effect of sparteine sulfate on uterine prostaglandin F in the rat.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Female; Indomethacin; Pregnancy; Prostagla | 1978 |
The effects of the administration of fenoprofen or indomethacin to rat dams during late pregnancy, with special reference to the ductus arteriosus of the fetuses and neonates.
Topics: Animals; Animals, Newborn; Body Weight; Ductus Arteriosus; Ductus Arteriosus, Patent; Female; Fenopr | 1978 |
Inhibition of fetal lung maturation by indomethacin in pregnant rabbits.
Topics: Animals; Female; Fetal Blood; Fetus; Gestational Age; Hydrocortisone; Indomethacin; Lung; Maternal-F | 1978 |
[Indomethacin and prostaglandins in labor].
Topics: Female; Humans; Indomethacin; Labor, Obstetric; Pregnancy; Prostaglandins | 1978 |
Effect on neonate of maternal treatment with indomethacin.
Topics: Female; Fetus; Humans; Indomethacin; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exch | 1979 |
Prostaglandin F2alpha production by the brain and its role in LH secretion.
Topics: Animals; Estradiol; Estrus; Female; Gonadotropin-Releasing Hormone; Hypothalamus; Indomethacin; Lute | 1976 |
Studies on closure of the ductus arteriosus. XII. In utero effect of indomethacin and sodium salicylate in rats and rabbits.
Topics: Animals; Cyclooxygenase Inhibitors; Depression, Chemical; Dose-Response Relationship, Drug; Ductus A | 1975 |
Periovulatory changes in ovarian prostaglandin formation and their hormonal control in the rat.
Topics: Animals; Depression, Chemical; Female; Follicle Stimulating Hormone; Indomethacin; Luteinizing Hormo | 1975 |
The influence of metyrapone on the synthesis and release of prostaglandins from the pregnant rat uterus in vitro.
Topics: Animals; Female; Indomethacin; Metyrapone; Pregnancy; Pregnancy, Animal; Prostaglandin-Endoperoxide | 1975 |
Effects of indomethacin on corpus luteum function and pregnancy in rhesus monkeys.
Topics: Amniotic Fluid; Animals; Corpus Luteum; Erythrocyte Count; Estradiol; Estrogens; Female; Fetus; Gest | 1976 |
[The effect of prostaglandin F2alpha on pregnancy in rats and attempts to counteract its abortifacient action].
Topics: Abortifacient Agents; Animals; Aspirin; Dose-Response Relationship, Drug; Female; Gestational Age; I | 1976 |
[Problems of rheumatic therapy in pregnancy (author's transl)].
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Chloroquine; Female; Fetal Diseases | 1976 |
The effect of estrogen upon cyclic nucleotide and prostaglandin levels in the rat uterus.
Topics: Animals; Arachidonic Acids; Endometrium; Estradiol; Estrus; Female; Indomethacin; Kinetics; Microsom | 1976 |
Uterine artery blood flow studies in the pregnant monkey.
Topics: Angiotensin II; Animals; Arteries; Blood Pressure; Diazoxide; Female; Furosemide; Haplorhini; Indome | 1976 |
The effect of prostaglandin E2 on the cardiovascular response to angiotensin II in pregnant rabbits.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Synergism; Female; I | 1977 |
Evidence for a role for prosaglandins in the initiation of blastocyst implantation in the rat.
Topics: Animals; Capillary Permeability; Coloring Agents; Embryo Implantation; Embryo Implantation, Delayed; | 1977 |
Studies on the effects of pharmacologic doses of cortisone acetate and several nonsteroidal anti-inflammatory compounds on ovo-implantation, early pregnancy, and the deciduomal response in the rat.
Topics: Animals; Cortisone; Decidua; Embryo Implantation; Embryonic Development; Estrone; Female; Flufenamic | 1977 |
Effect of indomethacin and cyproheptadine on onset of labour in rats.
Topics: Animals; Cyproheptadine; Drug Therapy, Combination; Female; Indomethacin; Labor, Obstetric; Pregnanc | 1977 |
The effect of indomethacin on plasma levels of prostaglandin F2alpha in women in labour.
Topics: Female; Humans; Indomethacin; Labor, Obstetric; Pregnancy; Prostaglandins F; Time Factors | 1977 |
Indomethacin: studies of absorption and placental transfer.
Topics: Amniotic Fluid; Animals; Female; Indomethacin; Maternal-Fetal Exchange; Placenta; Pregnancy; Rabbits | 1977 |
The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Child; Chloroquine; Female; Gold; Humans; Hydroxychl | 1977 |
Relationship between the uterotonic action of oxytocin and prostaglandins: oxytocin action and release of PG-activity in isolated nonpregnant and pregnant rat uteri.
Topics: Animals; Diclofenac; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indomethacin; Ox | 1977 |
Intraovarian release of eggs in the rat after indomethacin treatment at pro-oestrus.
Topics: Animals; Female; Indomethacin; Ovary; Ovulation; Pregnancy; Proestrus; Rats | 1976 |
Relationship between oestrogen, prostaglandin F2alpha and histamine in delayed implantation in the mouse.
Topics: Animals; Blastocyst; Embryo Implantation; Estrogens; Female; Indomethacin; Mice; Pregnancy; Progeste | 1976 |
Effects of relaxin on early pregnancy in rats.
Topics: Animals; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Resorption; | 1976 |
Effects of prostaglandins on RNA and casein synthesis in mammary gland explants of mice.
Topics: Animals; Breast; Caseins; Female; In Vitro Techniques; Indomethacin; Mice; Pregnancy; Prolactin; Pro | 1976 |
A study of the possible role of prostaglandins in decidualization using a nonsurgical method for the instillation of fluids into the rat uterine lumen.
Topics: Animals; Arachidonic Acids; Decidua; Female; Indomethacin; Pregnancy; Prostaglandin Antagonists; Pro | 1976 |
The effect of PGE2 and PGF2alpha on the response of guinea pig myometrium to adenine nucleotides in vitro.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals | 1976 |
The effects of combined dexamethasone and indomethacin treatment on the outcome of pregnancy in the rabbit.
Topics: Animals; Dexamethasone; Female; Indomethacin; Obstetric Labor, Premature; Pregnancy; Pregnancy, Anim | 1976 |
[Inhibition of endogenous prostaglandin synthesis by indomethacin in the treatment of premature labor].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy; Prostaglandin | 1976 |
Post-implantation termination of pregnancy in rats.
Topics: Abortifacient Agents; Alkaline Phosphatase; Aminoglutethimide; Animals; Cyclofenil; Diethylstilbestr | 1976 |
Radioimmunoassay for urinary metabolites of prostaglandin F2alpha.
Topics: Animals; Aspirin; Estradiol; Estrus; Female; Guinea Pigs; Humans; Hysterectomy; Immune Sera; Immuniz | 1976 |
Indomethacin to stop premature labor.
Topics: Animals; Female; Indomethacin; Obstetric Labor, Premature; Pregnancy; Rats | 1976 |
Possible association between maternal indomethacin therapy and primary pulmonary hypertension of the newborn.
Topics: Adolescent; Female; Humans; Hypertension, Pulmonary; Indomethacin; Infant, Newborn; Infant, Newborn, | 1976 |
Dose-response effects of prostaglandin F2alpha on the rabbit oviduct: reproductive endocrine influence and tachyphylaxis.
Topics: Animals; Blood Pressure; Dose-Response Relationship, Drug; Estrus; Fallopian Tubes; Female; Indometh | 1976 |
Prostaglandin F and progesterone secretion by porcine endometrium and corpus luteum in vitro.
Topics: Animals; Corpus Luteum; Endometrium; Estrus; Female; In Vitro Techniques; Indomethacin; Pregnancy; P | 1976 |
Corpus luteum function in the ewe: effect of PGF2alpha and prostaglandin synthetase inhibitors.
Topics: Acetates; Animals; Arachidonic Acids; Aspirin; Corpus Luteum; Dexamethasone; Estrus; Female; Flufena | 1976 |
Does prostaglandin F2alpha released from the uterus by oxytocin mediate the oxytocic action of oxytocin?
Topics: Animals; Estrus; Female; Indomethacin; Myometrium; Oxytocin; Pregnancy; Pressure; Prostaglandins F; | 1976 |
Effects of oxytocin on in vitro ovarian contractility during the estrous cycle of the rat.
Topics: Animals; Estrus; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Ovar | 1976 |
Prostaglandins: a possible regulator of muscle tone in the ductus arteriosus.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Female; Glutathione; Heart Septal Defects; Humans; Ind | 1976 |
Studies of the uterine circulation in the pregnant rabbit.
Topics: Animals; Blood Pressure; Female; Homeostasis; Hypertension; Hypotension; Indomethacin; Nephrectomy; | 1976 |
A proposed sequence of hormones controlling the induction of luteal 20alpha-hydroxy steroid dehydrogenase and progesterone withdrawal in the late-pregnant rat.
Topics: Aminoglutethimide; Animals; Corpus Luteum; Enzyme Induction; Female; Gonadotropins; Hydroxysteroid D | 1976 |
The effect of indomethacin on uterine contractility and luteal regression in pregnant rats at term.
Topics: Animals; Corpus Luteum; Estradiol; Female; Gestational Age; Hydroxysteroid Dehydrogenases; Indometha | 1976 |
The role of prostagandins in the control of uterine blood flow.
Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Dogs; Female; Humans; In Vitro Techniques; Indo | 1976 |
Uterine prostaglandin E secretion and uterine blood flow in the pregnant rabbit.
Topics: Animals; Blood Pressure; Cardiac Output; Cerium Isotopes; Chromatography; Depression, Chemical; Fema | 1975 |
Effect of indomethacin on blood plasma levels of LH and testosterone in male rats.
Topics: Animals; Cross Reactions; Female; Fertility; Follicle Stimulating Hormone; Indomethacin; Luteinizing | 1975 |
The effect of drugs on implantation in rats with an intrauterine device in one horn of the uterus.
Topics: Administration, Oral; Animals; Aspirin; Copulation; Embryo Implantation; Fallopian Tubes; Female; In | 1975 |
Lamb ductus arteriosus: effect of prostaglandin synthesis inhibitors on the muscle tone and the response to prostaglandin E2.
Topics: Animals; Arachidonic Acids; Depression, Chemical; Ductus Arteriosus; Female; Indomethacin; Muscle Co | 1975 |
Indomethacin, ketoprofen and corpus luteum regression in the guinea-pig.
Topics: Animals; Anti-Inflammatory Agents; Benzophenones; Corpus Luteum; Estrus; Female; Glass; In Vitro Tec | 1975 |
Evidence for a possible foetal control of prostaglandin release from the pregnant rat uterus in vitro.
Topics: Animals; Arachidonic Acids; Female; Fetus; In Vitro Techniques; Indomethacin; Ligation; Phospholipas | 1975 |
The antagonism by anti-inflammatory analgesics of prostaglandin f 2 alpha-induced contractions of human and rabbit myometrium in vitro.
Topics: Abortion, Induced; Animals; Anti-Inflammatory Agents; Aspirin; Drug Antagonism; Female; Ibuprofen; I | 1975 |
The effect of indomethacin of HMG-HCG induced ovulation in the phesus monkey.
Topics: Animals; Chorionic Gonadotropin; Estradiol; Estrone; Female; Indomethacin; Macaca mulatta; Menotropi | 1975 |
The effects of dexamethasone and indomethacin on the outcome of pregnancy in the rabbit.
Topics: Administration, Oral; Animals; Dexamethasone; Female; Hematocrit; Indomethacin; Injections, Subcutan | 1975 |
On the role of prostaglandins in parturition in the rat.
Topics: Animals; Female; Gestational Age; Hypophysectomy; Indomethacin; Labor, Obstetric; Medroxyprogesteron | 1975 |
Prostaglandin specific binding in hamster myometrial low speed supernatant.
Topics: Animals; Binding Sites; Charcoal; Cricetinae; Estrus; Female; Indomethacin; Mesocricetus; Myometrium | 1975 |
[Phocomelia and agenesis of the penis in a newborn infant. Possible teratogenic role of a drug taken by the mother during pregnancy].
Topics: Abnormalities, Drug-Induced; Ectromelia; Female; Humans; Indomethacin; Infant; Infant, Newborn; Male | 1975 |
Effect of osteoclast activating factor from human leukocytes on bone metabolism.
Topics: Animals; Bone and Bones; Bone Resorption; Calcitonin; Calcium; Calcium Radioisotopes; Collagen; Dose | 1975 |
Steroid-independent effect of gonadotropins on prostaglandin synthesis in rat Graafian follicles in vitro.
Topics: Animals; Antibody Specificity; Diestrus; Estrus; Female; Follicle Stimulating Hormone; Immune Sera; | 1975 |
[Indomethacin as an inhibitor of premature labor].
Topics: Adult; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy | 1975 |
[Effect of F-2 alpha prostaglandin on the induction and development of contractions in rat's myometrium].
Topics: Animals; Female; Indomethacin; Myometrium; Pregnancy; Prostaglandins F; Rats; Uterine Contraction | 1975 |
Premature labor and indomethacin.
Topics: Adult; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Prostaglandins F; Time F | 1975 |
Abortifacient effects of Vibrio cholerae exo-enterotoxin and endotoxin in mice.
Topics: Abortifacient Agents; Animals; Decidua; Embryo, Mammalian; Endotoxins; Enterotoxins; Female; Indomet | 1975 |
Effects of indomethacin and prostaglandin F2alpha on parturition in the hamster.
Topics: Animals; Cricetinae; Female; Indomethacin; Labor, Obstetric; Pregnancy; Prostaglandins F | 1975 |
Plasma progesterone levels in guinea-pigs actively immunized against prostaglandin F2alpha, hysterectomized or treated with intra-uterine indomethacin.
Topics: Animals; Antibody Formation; Corpus Luteum; Cross Reactions; Estrus; Female; Guinea Pigs; Hysterecto | 1975 |
Indomethacin induces rat uterine contractions in vitro and alters reactivity to calcium and acetylcholine.
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Indo | 1976 |
Letter: Indomethacin.
Topics: Animals; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy | 1976 |
Effect of indomethacin on egg transport and pregnancy in the rabbit.
Topics: Animals; Embryo Implantation; Female; Indomethacin; Pregnancy; Pregnancy, Animal; Rabbits | 1976 |
Efficacy of various locally applied chemicals as contragestational agents in rats.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Cyclizine; Drug Evaluation, Preclini | 1976 |
Effects of indomethacin and ICI 46,474 administered during ovum transport on fertility in rabbits.
Topics: Animals; Embryo Implantation; Female; Fertility; Indomethacin; Insemination, Artificial; Ovum Transp | 1976 |
Effects of indomethacin on fetal renal function, renal and umbilicoplacental blood flow and lung liquid production.
Topics: Animals; Blood Pressure; Carbon Dioxide; Electrolytes; Extravascular Lung Water; Female; Fetal Blood | 1992 |
Any physiological role for prostacyclin in regulation of fetal vessel tone?
Topics: 6-Ketoprostaglandin F1 alpha; Arginine; Blood Vessels; Bradykinin; Cyclic GMP; Endothelium, Vascular | 1992 |
Regulation of steroid synthesis and metabolism in isolated binucleate cells of the placenta in sheep and goats.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Arachidonic Acid; Dinoprostone; Female; Goats; Indomethacin; M | 1992 |
Indomethacin for the treatment of symptomatic leiomyoma uteri during pregnancy.
Topics: Adult; Drug Administration Schedule; Female; Humans; Indomethacin; Leiomyoma; Palliative Care; Pregn | 1992 |
Indomethacin for the treatment of polyhydramnios: a case of constriction of the ductus arteriosus.
Topics: Adult; Constriction, Pathologic; Ductus Arteriosus; Echocardiography; Female; Fetal Heart; Fetal Mon | 1992 |
[Indomethacin in threatening premature labor. Fetal and neonatal cardiovascular effects].
Topics: Cardiovascular Diseases; Female; Fetal Diseases; Humans; Hypertension, Pulmonary; Indomethacin; Infa | 1992 |
Pregnancy reduces serotonin-induced contraction of guinea pig uterine and carotid arteries.
Topics: Animals; Arginine; Arteries; Carotid Arteries; Female; Guinea Pigs; In Vitro Techniques; Indomethaci | 1992 |
Fetal indomethacin exposure and renal dysgenesis.
Topics: Female; Fetofetal Transfusion; Fetus; Humans; Indomethacin; Kidney Diseases; Pregnancy; Twins, Monoz | 1992 |
Pharmacological properties of acetylcholine mediated relaxation of the human umbilical artery.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Arginine; Female; Humans; In Vitro Techniques; Indomethacin | 1992 |
Oligohydramnios induced by maternal indomethacin therapy.
Topics: Female; Humans; Indomethacin; Maternal-Fetal Exchange; Obstetric Labor, Premature; Oligohydramnios; | 1992 |
Indomethacin therapy and chronic hemodialysis during pregnancy. A case report.
Topics: Adult; Female; Glomerulosclerosis, Focal Segmental; Humans; Indomethacin; Infant, Newborn; Obstetric | 1992 |
Prostaglandin synthesis inhibition prevents placental dysfunction after fetal cardiac bypass.
Topics: Analysis of Variance; Animals; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Fetus; I | 1992 |
Antenatal presentation of a child with congenital lobar emphysema.
Topics: Adult; Cystic Adenomatoid Malformation of Lung, Congenital; Female; Humans; Indomethacin; Infant, Ne | 1992 |
The maternal hemodynamic effect of indomethacin in normal pregnancy.
Topics: Blood Pressure; Cardiac Output; Female; Heart Rate; Hemodynamics; Humans; Indomethacin; Pregnancy; V | 1992 |
Intraoperative amniocentesis and indomethacin treatment in the management of an immature pregnancy with completely dilated cervix.
Topics: Adult; Amniocentesis; Cervix Uteri; Female; Humans; Indomethacin; Infant, Newborn; Intraoperative Pe | 1992 |
Endothelium-derived relaxing factor and indomethacin-sensitive contracting factor alter arterial contractile responses to thromboxane during pregnancy.
Topics: Animals; Arteries; Carotid Arteries; Endothelium, Vascular; Female; Guinea Pigs; In Vitro Techniques | 1992 |
Randomized comparative trial of indomethacin and sulindac for the treatment of refractory preterm labor.
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Randomized Controlled Trials as | 1992 |
Probable influence of ova and embryo prostaglandins in the differential ovum transport in pregnant and cycling rats.
Topics: Alprostadil; Animals; Dinoprost; Dinoprostone; Embryo, Mammalian; Estrus; Female; Indomethacin; Ovum | 1992 |
Role of prostaglandins in the metabolic responses of the fetus to hypoxia.
Topics: Animals; Blood Glucose; Carbon Dioxide; Dinoprostone; Female; Fetal Blood; Fetal Hypoxia; Hydrogen-I | 1992 |
Endothelium-derived relaxation of the pregnant and nonpregnant canine uterine artery.
Topics: Acetylcholine; Animals; Benzoquinones; Calcimycin; Dogs; Dose-Response Relationship, Drug; Endotheli | 1992 |
Isolated pulmonary resistance vessels from fetal lambs. Contractile behavior and responses to indomethacin and endothelin-1.
Topics: Animals; Delivery, Obstetric; Endothelins; Female; Fetus; In Vitro Techniques; Indomethacin; Lung; M | 1992 |
Uterine prostaglandin production in ovine pregnancy: effects of angiotensin II and indomethacin.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Female; Hemodynamics; Indomethacin; Pregn | 1992 |
Effect of partial starvation on in vitro spontaneous activity and glycogen levels of uterine smooth muscle from pregnant and non pregnant rats.
Topics: Animals; Fallopian Tubes; Female; Glycogen; In Vitro Techniques; Indomethacin; Isometric Contraction | 1990 |
Prostaglandin E2 and fetal oxygen tension synergistically inhibit response of isolated fetal rabbit ductus arteriosus to norepinephrine.
Topics: Animals; Dinoprostone; Drug Synergism; Ductus Arteriosus; Female; Fetus; In Vitro Techniques; Indome | 1991 |
Role of cyclic adenosine 3',5'-monophosphate in mediating the effect of prostaglandin E2 on decidualization in vitro.
Topics: 1-Methyl-3-isobutylxanthine; Alkaline Phosphatase; Animals; Cell Nucleus; Cells, Cultured; Cholera T | 1991 |
Evidence for two antigenically distinct molecular weight variants of prostaglandin H synthase in the rat ovary.
Topics: Animals; Corpus Luteum; Epitopes; Female; Fluorescent Antibody Technique; Gene Expression Regulation | 1991 |
Effects of acid and basic fibroblast growth factor and heparin on resorption of cultured fetal rat long bones.
Topics: Animals; Aphidicolin; Bone and Bones; Bone Resorption; Culture Techniques; Female; Fibroblast Growth | 1991 |
Urinary excretion of prostacyclin and thromboxane metabolites in threatened preterm labor: effect of indomethacin and nylidrin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Epoprostenol; Female; Humans; Indomethacin; Kinetics; Nylidrin; | 1992 |
PGE2-independent immunosuppressive activity of horse trophoblast tissue.
Topics: Animals; Dinoprostone; Female; Horses; Indomethacin; Lymphocyte Activation; Pregnancy; Pregnancy, An | 1992 |
Indomethacin therapy and fetal urine production in twins with polyhydramnios.
Topics: Administration, Oral; Administration, Rectal; Adult; Amniotic Fluid; Female; Fetus; Humans; Indometh | 1991 |
Intrauterine capsules for incubation of gametes and subsequent release of embryos.
Topics: Adult; Agar; Animals; Capsules; Embryo, Mammalian; Female; Fertilization in Vitro; Gamete Intrafallo | 1991 |
Evidence for direct non-genomic effects of triiodothyronine on bone rudiments in rats: stimulation of the inositol phosphate second messenger system.
Topics: Animals; Bone and Bones; Cells, Cultured; Chromatography, High Pressure Liquid; Diiodotyrosine; Dose | 1991 |
Arachidonic acid metabolism in cultured astrocytes: presence of 12-lipoxygenase activity in the intact cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-a | 1991 |
Role of prostaglandins and leukotrienes in the synergistic effect of oxytocin and corticotropin-releasing hormone (CRH) on the contraction force in human gestational myometrium.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Benzeneacetamides; Corticotropin-Relea | 1991 |
Reversal of indomethacin-induced inhibition of implantation in the mouse by epidermal growth factor.
Topics: Animals; Dose-Response Relationship, Drug; Embryo Implantation; Epidermal Growth Factor; Female; Ind | 1991 |
[Use of indomethacin in the therapy of poly-hydramnios. Description and comments on a case].
Topics: Adult; Amniotic Fluid; Diuresis; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Pregnancy | 1991 |
[Neuralgiform paroxysmal migraine].
Topics: Abortion, Induced; Adult; Cerebral Angiography; Cluster Headache; Diagnosis, Differential; Female; H | 1991 |
Onset of the constrictive effect of indomethacin on the ductus arteriosus in fetal rats.
Topics: Animals; Dinoprostone; Ductus Arteriosus; Female; Fetus; Gestational Age; Indomethacin; Pregnancy; R | 1991 |
Disposition kinetics in the rat fetus.
Topics: Animals; Diazepam; Female; Fetus; Indomethacin; Kinetics; Maternal-Fetal Exchange; Models, Biologica | 1991 |
Endothelium-independent relaxation of rabbit coronary artery by 17 beta-oestradiol in vitro.
Topics: Animals; Aorta, Thoracic; Arginine; Calcium Channel Blockers; Coronary Vessels; Endothelium, Vascula | 1991 |
The effects of indomethacin and prostaglandin E2 on the ethanol-induced suppression of ovine fetal breathing movements.
Topics: Animals; Dinoprostone; Drug Antagonism; Ethanol; Female; Fetus; Indomethacin; Maternal-Fetal Exchang | 1991 |
Postcopulatory myometrial activity in the rat as seen by video-laparoscopy.
Topics: Animals; Cervix Uteri; Copulation; Female; Fertility; Genitalia, Male; Indomethacin; Laparoscopy; Ma | 1991 |
Suppression by human placental protein 14 of natural killer cell activity.
Topics: Cells, Cultured; Cytotoxicity, Immunologic; Female; Glycodelin; Glycoproteins; Humans; Immune Tolera | 1991 |
Doppler echocardiography of fetal ductus arteriosus constriction versus increased right ventricular output.
Topics: Blood Flow Velocity; Ductus Arteriosus; Echocardiography, Doppler; Female; Fetal Heart; Gestational | 1991 |
Patent ductus arteriosus, indomethacin, and intestinal distension: effects on intestinal blood flow and oxygen consumption.
Topics: Animals; Animals, Newborn; Blood Flow Velocity; Ductus Arteriosus, Patent; Female; Ileum; Indomethac | 1991 |
Renal dysgenesis in a monozygotic twin: association with in utero exposure to indomethacin.
Topics: Adult; Diseases in Twins; Female; Humans; Indomethacin; Infant, Newborn; Kidney; Maternal-Fetal Exch | 1991 |
Cocaine and indomethacin: fetal anuria, neonatal edema, and gastrointestinal bleeding.
Topics: Adult; Anuria; Cocaine; Drug Synergism; Female; Fetal Diseases; Gastrointestinal Hemorrhage; Humans; | 1991 |
Acute recurrent polyhydramnios--management with indomethacin.
Topics: Acute Disease; Adult; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Recurrence; Uterine C | 1991 |
[Effect of vasopressin and indomethacin on provoked diuresis in pregnant and non-pregnant Meriones crassus].
Topics: Animals; Diuresis; Female; Gerbillinae; Indomethacin; Pregnancy; Pregnancy, Animal; Prostaglandins; | 1991 |
A product of activated human granulocytes stimulates prostaglandin E2 synthesis in human amnion cells.
Topics: Amnion; Cells, Cultured; Chorioamnionitis; Cytochalasin B; Dinoprostone; Epidermal Growth Factor; Fe | 1991 |
Maternal plasma corticotrophin-releasing hormone--elevated in preterm labour but unaffected by indomethacin or nylidrin.
Topics: Adult; Corticotropin-Releasing Hormone; Female; Humans; Hydrocortisone; Indomethacin; Nylidrin; Obst | 1991 |
Contraction and prostaglandin biosynthesis by myometrium from non-pregnant and pregnant rabbits in response to adenosine 5'-triphosphate.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Female; In Vitro Techniques; I | 1991 |
Indomethacin for preterm labor: fetal toxicity in a dizygotic twin gestation.
Topics: Abnormalities, Drug-Induced; Adult; Diseases in Twins; Drug Monitoring; Ductus Arteriosus; Female; F | 1991 |
Effects of indomethacin in utero on the pulmonary vasculature of the newborn lambs.
Topics: Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Cardiac Output; Ductus Arteriosus; Fe | 1991 |
Uterine activity and decidual prostaglandin production in women in early pregnancy in response to mifepristone with or without indomethacin in vivo.
Topics: Culture Techniques; Decidua; Female; Humans; Indomethacin; Mifepristone; Pregnancy; Pregnancy Trimes | 1991 |
Enhanced endothelium-derived relaxing factor activity in pregnant, spontaneously hypertensive rats.
Topics: Animals; Arginine; Blood Pressure; Female; Heart Rate; Indomethacin; Nitric Oxide; omega-N-Methylarg | 1991 |
Indomethacin induces hypertensive crisis in preeclampsia irrespective of prior antihypertensive drug therapy.
Topics: Antihypertensive Agents; Drug Antagonism; Female; Humans; Hypertension; Indomethacin; Pre-Eclampsia; | 1991 |
The potentiating effect of pregnancy on humoral immune responses of mice.
Topics: Abortion, Veterinary; Animals; Antibody Formation; B-Lymphocytes; Female; Haptens; Immunoglobulins; | 1991 |
Common biochemical pathway of dysmorphogenesis in murine embryos: use of the glucocorticoid pathway by phenytoin.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cortodoxone; Cyclooxygenase Inhibitors; Embryo, Mammal | 1990 |
Long-term indomethacin therapy decreases fetal urine output and results in oligohydramnios.
Topics: Adult; Amniotic Fluid; Female; Fetus; Humans; Indomethacin; Obstetric Labor, Premature; Oligohydramn | 1991 |
Treatment of polyhydramnios with indomethacin.
Topics: Adult; Female; Humans; Indomethacin; Kidney Diseases; Polyhydramnios; Pregnancy; Tocolysis | 1991 |
Failure of in vitro-expanded hyperimmune cytotoxic T lymphocytes to affect survival of mouse embryos in vivo.
Topics: Animals; Cells, Cultured; Embryo, Mammalian; Female; Fetal Death; Graft Survival; Immune Tolerance; | 1991 |
Exogenous progesterone or indomethacin delays parturition in the viviparous lizard Sceloporus jarrovi.
Topics: Animals; Female; Indomethacin; Labor, Obstetric; Lizards; Pregnancy; Progesterone | 1991 |
Magnesium sulfate-induced relaxation of uterine arteries from pregnant and nonpregnant patients.
Topics: Adult; Arteries; Calcium Chloride; Dose-Response Relationship, Drug; Drug Antagonism; Endothelium; F | 1991 |
Effects of indomethacin, during pregnancy in the rat, on responses to noradrenaline and angiotensin II in vivo, and responses to phenylephrine in vitro.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Indomethacin; Norepinephrine; Phenylephrine; Pregna | 1990 |
Effect of indomethacin on materno-fetal amino acid transfer in the dual-perfused human placental cotyledon.
Topics: Amino Acids; Aminoisobutyric Acids; Female; Humans; In Vitro Techniques; Indomethacin; Maternal-Feta | 1990 |
Indomethacin reversal of ethanol-induced suppression of ovine fetal breathing movements and relationship to prostaglandin E2.
Topics: Animals; Blood Gas Analysis; Blood Pressure; Dinoprostone; Ethanol; Female; Fetal Blood; Fetus; Indo | 1990 |
Prostacyclin producing activity of human umbilical blood vessels in adrenergic innervated and non-innervated portions.
Topics: Adrenergic Fibers; Epoprostenol; Female; Humans; Indomethacin; Kinetics; Microscopy, Fluorescence; P | 1990 |
Prostaglandin G/H synthase activity in ovine cotyledons: a gestational profile.
Topics: Animals; Arachidonic Acids; Cyclooxygenase Inhibitors; Female; Gestational Age; Hypophysectomy; Indo | 1990 |
A method to inject the umbilical vein of the rat.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Female; Fetus; Half-Life; Indo | 1990 |
Prostaglandin-mediated inactivation of natural killer cells in the murine decidua.
Topics: Animals; Cytotoxicity, Immunologic; Decidua; Dinoprostone; Female; Immune Tolerance; Immunity, Innat | 1990 |
Transplacental cardiovascular effects of four popular analgesics in rats.
Topics: Acetaminophen; Analgesics; Animals; Aspirin; Cardiomegaly; Constriction, Pathologic; Ductus Arterios | 1990 |
Effects of magnesium and isradipine on contractile activation induced by the thromboxane A2 analog U46619 in human uteroplacental arteries in term pregnancy.
Topics: Antihypertensive Agents; Arteries; Calcium Channel Blockers; Digoxin; Female; Humans; Indomethacin; | 1990 |
Mechanism of action of interleukin-1 beta in increasing corticotropin-releasing factor and adrenocorticotropin hormone release from cultured human placental cells.
Topics: Adrenocorticotropic Hormone; Cells, Cultured; Corticotropin-Releasing Hormone; Cyclic AMP; Cyclic GM | 1990 |
Maternal indomethacin therapy in the treatment of polyhydramnios.
Topics: Administration, Oral; Administration, Rectal; Adult; Amniotic Fluid; Drug Evaluation; Female; Follow | 1990 |
Effect of indomethacin on the fetal ductus arteriosus during treatment of symptomatic polyhydramnios.
Topics: Ductus Arteriosus; Echocardiography; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Tricus | 1990 |
Uterine blood flow velocity waveforms in pregnant women during indomethacin therapy.
Topics: Blood Flow Velocity; Female; Humans; Indomethacin; Obstetric Labor, Premature; Polyhydramnios; Pregn | 1990 |
Indomethacin treatment for polyhydramnios and subsequent infantile nephrogenic diabetes insipidus.
Topics: Adult; Diabetes Insipidus; Female; Humans; Indomethacin; Infant, Newborn; Kidney Diseases; Polyhydra | 1990 |
[Recurrent acute polyhydramnios treated with indomethacin].
Topics: Acute Disease; Adult; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Pregnancy Outcome; Re | 1990 |
TRAP sequence--successful outcome with indomethacin treatment.
Topics: Abnormalities, Severe Teratoid; Adult; Female; Fetofetal Transfusion; Humans; Indomethacin; Infant, | 1990 |
Venous and hepatic vascular responses to indomethacin and prostaglandin E1 in the fetal lamb.
Topics: Alprostadil; Animals; Blood Circulation; Blood Pressure; Female; Fetus; Indomethacin; Liver; Microsp | 1990 |
[Morphological characteristics of the thymus gland of albino rats after prenatal administration of indomethacin].
Topics: Adrenergic Fibers; Age Factors; Animals; Animals, Newborn; Cell Count; Female; Fetus; Indomethacin; | 1990 |
Does indomethacin alter the hemodynamic response to magnesium sulfate infusion and hemorrhage in gravid ewes?
Topics: Acid-Base Equilibrium; Animals; Female; Fetus; Hemodynamics; Hemorrhage; Indomethacin; Magnesium; Ma | 1990 |
Relationship between maternal milk PGE2 and gastric acid secretion in newborn rats.
Topics: Animals; Animals, Newborn; Chlorides; Dinoprostone; Female; Gastric Acid; Gastric Juice; Gastric Muc | 1990 |
Effects of magnesium on isolated human fetal and maternal uteroplacental vessels.
Topics: Arteries; Calcium; Dinoprost; Drug Interactions; Endothelium, Vascular; Female; Humans; In Vitro Tec | 1990 |
Cerebral lesions in preterm infants after tocolytic indomethacin.
Topics: Administration, Rectal; Brain; Brain Damage, Chronic; Cerebral Hemorrhage; Dose-Response Relationshi | 1990 |
[The persistent pulmonary hypertension syndrome in neonates after intrauterine exposure to indomethacin].
Topics: Female; Fetus; Humans; Indomethacin; Infant, Newborn; Male; Persistent Fetal Circulation Syndrome; P | 1990 |
Safety and efficacy of long-term tocolysis with indomethacin.
Topics: Apgar Score; Birth Weight; Female; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature | 1990 |
Arginine vasotocin-induced prostaglandin synthesis in vitro by the reproductive tract of the viviparous lizard Sceloporus jarrovi.
Topics: Animals; Arachidonic Acids; Dinoprost; Dinoprostone; Female; In Vitro Techniques; Indomethacin; Kine | 1990 |
Oligohydramnios in each sac of a triplet gestation caused by Motrin--fulfilling Kock's postulates.
Topics: Adult; Amniotic Fluid; Female; Humans; Ibuprofen; Indomethacin; Obstetric Labor, Premature; Pregnanc | 1990 |
Placental transfer of indomethacin in the human pregnancy.
Topics: Amniotic Fluid; Female; Gestational Age; Humans; Indomethacin; Maternal-Fetal Exchange; Pregnancy | 1990 |
Activation of maternal killer cells in the pregnant uterus with chronic indomethacin therapy, IL-2 therapy, or a combination therapy is associated with embryonic demise.
Topics: Abortion, Induced; Animals; Cytotoxicity, Immunologic; Decidua; Dinoprostone; Female; Immune Toleran | 1990 |
Indomethacin and ischemic brain injury in neonates.
Topics: Brain Ischemia; Diseases in Twins; Encephalomalacia; Female; Humans; Indomethacin; Infant, Newborn; | 1990 |
PGF2 alpha and PGE2 binding to rat myometrium during gestation, parturition, and postpartum.
Topics: Abortion, Spontaneous; Animals; Cell Membrane; Dinoprost; Dinoprostone; Female; Indomethacin; Kineti | 1990 |
Oligohydramnios associated with prostaglandin synthetase inhibitors in preterm labour.
Topics: Adult; Amniotic Fluid; Birth Weight; Female; Gestational Age; Humans; Ibuprofen; Indomethacin; Infan | 1990 |
Shirodkar cerclage in a multifactorial approach to the patient with advanced cervical changes.
Topics: Anti-Bacterial Agents; Combined Modality Therapy; Female; Humans; Indomethacin; Methods; Pregnancy; | 1990 |
Induction of cleft palate in mice by inhibitors of prostaglandin synthesis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cleft Palate; Diclofenac; Female; Indomethacin; In | 1990 |
Developmental changes in the umbilical arteries with observation of the effects of indomethacin in fetal rats.
Topics: Animals; Female; Freezing; Gestational Age; Indomethacin; Pregnancy; Rats; Time Factors; Umbilical A | 1990 |
A novel enhancing effect of platelet activating factor (PAF) on glucose oxidation in uteri from pregnant rats. Participation of prostaglandins and leukotrienes.
Topics: Animals; Carbon Monoxide; Chromones; Female; Glucose; Indomethacin; Leukotrienes; Masoprocol; Platel | 1990 |
Doppler assessment of the renal blood flow velocity waveform during indomethacin therapy for preterm labor and polyhydramnios.
Topics: Ductus Arteriosus; Female; Fetal Monitoring; Gestational Age; Humans; Indomethacin; Kidney; Maternal | 1990 |
Indomethacin therapy in the treatment of symptomatic polyhydramnios.
Topics: Adult; Amniocentesis; Diuresis; Female; Fetal Death; Fetal Monitoring; Fetus; Gestational Age; Human | 1990 |
The effect of indomethacin on the pulsatility index of the umbilical artery in human fetuses.
Topics: Blood Flow Velocity; Ductus Arteriosus; Female; Fetus; Humans; Indomethacin; Pregnancy; Pulse; Ultra | 1990 |
Polyhydramnios associated with a ring chromosome and low maternal serum alpha-fetoprotein levels managed with indomethacin.
Topics: alpha-Fetoproteins; Chromosome Aberrations; Female; Fetus; Humans; Indomethacin; Infant, Newborn; Ob | 1988 |
Inhibition of the oxygen-induced contraction of the isolated human umbilical artery by indomethacin, flurbiprofen, aspirin and drugs modifying Ca2+ disposition.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Influence of a stable prostacyclin analogue (iloprost) and cyclooxygenase inhibition on angiotensin-II in the perfused human placenta.
Topics: Angiotensin II; Blood Pressure; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Iloprost; I | 1989 |
Evidence for prostaglandins and leukotrienes as mediators of phase I of estrogen action in implantation in the mouse.
Topics: Animals; Cyclooxygenase Inhibitors; Dinoprostone; Embryo Implantation; Estriol; Female; Indomethacin | 1989 |
Neonatal renal dysfunction and intrauterine exposure to prostaglandin synthesis inhibitors.
Topics: Acute Kidney Injury; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Cesarean Section; Cyclo | 1989 |
Bradykinin produces pulmonary vasodilation in fetal lambs: role of prostaglandin production.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Bradykinin; Cyclooxygenase Inhibitors; Epoprostenol; Female; | 1989 |
Right ventricular concentric hypertrophy and left ventricular dilatation by ductal constriction in fetal rats.
Topics: Animals; Cardiomegaly; Constriction, Pathologic; Dilatation, Pathologic; Ductus Arteriosus; Female; | 1989 |
[Prescribing indomethacin to prevent premature labor. Risk of cardiomyopathy].
Topics: Cardiomyopathy, Dilated; Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Prema | 1989 |
Effect of dietary restriction on triglyceride levels in the uterus isolated from pregnant rats. Influences of prostaglandins and indomethacin.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Diet, Reducing; Female; Indometh | 1989 |
Antagonism of antihypertensive drug therapy in pregnancy by indomethacin?
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Indomethacin; Obstetric Labor, Prema | 1989 |
The role of T-kininogen and H and L kininogens in health and disease.
Topics: Animals; Animals, Newborn; Arthritis; Arthritis, Experimental; Dexamethasone; Female; Indomethacin; | 1989 |
Indomethacin antagonizes the ethanol-induced suppression of breathing activity but not the suppression of brain activity in the near-term fetal sheep.
Topics: Animals; Brain; Disease Models, Animal; Electroencephalography; Ethanol; Female; Fetus; Indomethacin | 1989 |
Effect of exogenous prostacyclin on central and uterine hemodynamics in the chronically instrumented pregnant guinea pig before and after indomethacin administration.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Epoprostenol; Female | 1989 |
Twin with hydramnios: treating premature labor at source.
Topics: Delivery, Obstetric; Female; Humans; Indomethacin; Obstetric Labor, Premature; Polyhydramnios; Pregn | 1989 |
Indomethacin-induced oligohydramnios.
Topics: Adult; Amniotic Fluid; Dose-Response Relationship, Drug; Female; Humans; Indomethacin; Obstetric Lab | 1989 |
Effect of indomethacin administration on glucose homeostasis and pancreatic hormones in lactating goats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Blood Glucose; Female; Glucagon; Gluconeogenesis; Goats; Home | 1989 |
Doppler assessment of the pulsatility index of the middle cerebral artery during constriction of the fetal ductus arteriosus after indomethacin therapy.
Topics: Blood Circulation; Cerebral Arteries; Ductus Arteriosus; Female; Fetus; Hemodynamics; Humans; Indome | 1989 |
[Prenatal diagnosis of premature closure of the ductus arteriosus with subsequent development of a non-immunologic hydrops fetalis].
Topics: Adult; Cesarean Section; Constriction, Pathologic; Ductus Arteriosus; Female; Humans; Hydrops Fetali | 1989 |
Prostaglandin F-2 alpha receptors in corpora lutea of pregnant rats and relationship with induction of 20 alpha-hydroxysteroid dehydrogenase.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; Animals; Corpus Luteum; Din | 1989 |
Role of platelet-activating factor (PAF) in the initiation of the decidual reaction in the rat.
Topics: Animals; Decidua; Diterpenes; Female; Ginkgolides; Indomethacin; Lactones; Plant Extracts; Platelet | 1989 |
Severe ovarian hyperstimulation syndrome: a reevaluated therapeutic approach.
Topics: Abortion, Missed; Adult; Ascites; Drainage; Electrolytes; Female; Humans; Indomethacin; Ovarian Dise | 1989 |
Effects of indomethacin on human placental stem villous arteries.
Topics: Arteries; Chorionic Villi; Chromatography, Gas; Female; Humans; Indomethacin; Isometric Contraction; | 1989 |
Role of prostaglandins in alcohol teratogenesis.
Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Ethanol; Female; Indomethacin; Mice; Mice, Inbred C57 | 1989 |
[Structure of the mesenteric lymph nodes in fetuses and offspring of white rats under the effect of indomethacin on the mother-fetus system].
Topics: Animals; Blood Cell Count; Female; Fetus; Indomethacin; Lymph Nodes; Lymphocytes; Maternal-Fetal Exc | 1989 |
Power spectrum analysis of myometrial electromyogram and intrauterine pressure changes in the pregnant rhesus monkey in late gestation.
Topics: Animals; Electromyography; Female; Food Deprivation; Fourier Analysis; Indomethacin; Macaca mulatta; | 1989 |
PGE2-mediated immunosuppression by first trimester human decidual cells blocks activation of maternal leukocytes in the decidua with potential anti-trophoblast activity.
Topics: Cytotoxicity, Immunologic; Decidua; Dinoprostone; Female; Humans; Immune Tolerance; Immunity, Cellul | 1989 |
Interleukin-1 stimulates prostaglandin biosynthesis by human amnion.
Topics: Amnion; Cells, Cultured; Dinoprostone; Dose-Response Relationship, Drug; Female; Humans; Indomethaci | 1989 |
[Indomethacin and lung maturity].
Topics: Amniotic Fluid; Animals; Dose-Response Relationship, Drug; Female; Fetal Organ Maturity; Indomethaci | 1989 |
Effects of indomethacin on spacing of conceptuses within the uterine horn and on fetal and placental growth in the rat.
Topics: Animals; Embryonic and Fetal Development; Female; Fertility; Fetus; Indomethacin; Male; Placenta; Pr | 1989 |
Prostaglandin synthesis and its inhibition by cyclic AMP and forskolin in postpartum follicles of the guppy (Poecilia reticulata).
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Colforsin; Cyclic AMP; Female; Fishes; Indomethacin; O | 1987 |
Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Casein | 1988 |
A postulated mechanism of beta-sympathomimetic induction of rib and limb anomalies in rat fetuses.
Topics: Abnormalities, Drug-Induced; Adrenergic beta-Agonists; Animals; Dibenzoxepins; Dose-Response Relatio | 1985 |
Preterm labor: its diagnosis and management.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Female; Fluid Therapy; Humans; Indomethacin; Infant, Ne | 1986 |
Treatment with prostaglandins reduces the antifertility effect of indomethacin in rabbits.
Topics: Animals; Embryo Implantation; Female; Fertility; Fetal Death; Indomethacin; Pregnancy; Progesterone; | 1986 |
Patent ductus arteriosus after prolonged treatment with indomethacin during pregnancy: case report.
Topics: Adult; Diseases in Twins; Ductus Arteriosus, Patent; Female; Humans; Indomethacin; Infant, Newborn; | 1987 |
In vitro studies on the control of human myometrial gap junctions.
Topics: Female; Humans; Indomethacin; Intercellular Junctions; Labor, Obstetric; Microscopy, Electron; Myome | 1987 |
Stimulant action of pethidine on the pregnant rat uterus in-vitro.
Topics: Animals; Drug Interactions; Female; In Vitro Techniques; Indomethacin; Meperidine; Methysergide; Pre | 1987 |
Effect of indomethacin on plasma levels of vitamin D metabolites, oestradiol and progesterone in rabbits during early pregnancy.
Topics: Animals; Binding, Competitive; Calcifediol; Calcitriol; Calcium; Estradiol; Female; Hydroxycholecalc | 1987 |
Strong prostaglandin associated suppression of the proliferation of human maternal lymphocytes by neonatal lymphocytes linked to T versus T cell interactions and differential PGE2 sensitivity.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Dinoprostone; Female; Fetal Blood; Humans; In Vi | 1985 |
[Results of clinical use of prostaglandin synthesis inhibitors in the complex treatment of threatened premature interruption of pregnancy].
Topics: Abortion, Threatened; Combined Modality Therapy; Female; Humans; Indomethacin; Pregnancy | 1986 |
Implication of prostaglandin E2 in soluble factor-mediated immune suppression by murine decidual cells.
Topics: Animals; Decidua; Dinoprost; Dinoprostone; Female; Immune Tolerance; In Vitro Techniques; Indomethac | 1986 |
In vitro oxytocic activity of platelet-activating factor on human myometrium.
Topics: Female; Humans; In Vitro Techniques; Indomethacin; Lipoxygenase; Masoprocol; Myometrium; Oxytocics; | 1987 |
Distinct mitogens reveal different mechanisms of suppressor activity in human cord blood.
Topics: Dinoprostone; Female; Fetal Blood; Humans; Immune Tolerance; In Vitro Techniques; Indomethacin; Infa | 1988 |
Defective IFN-gamma production in the human neonate. II. Role of increased sensitivity to the suppressive effects of prostaglandin E.
Topics: Adult; Age Factors; Dinoprostone; Female; Fetal Blood; Humans; Indomethacin; Infant, Newborn; Interf | 1985 |
Effects of epidermal growth factor, phorbol myristate acetate, and arachidonic acid on choriogonadotropin secretion by cultured human choriocarcinoma cells.
Topics: Arachidonic Acid; Arachidonic Acids; Caenorhabditis elegans Proteins; Carrier Proteins; Catechols; C | 1985 |
Characterization of prostanoid relaxant/inhibitory receptors (psi) using a highly selective agonist, TR4979.
Topics: Alprostadil; Animals; Cats; Chickens; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 1986 |
Prostacyclin does not change during an oxygen induced increase in pulmonary blood flow in the fetal lamb.
Topics: Animals; Blood Gas Analysis; Epoprostenol; Female; Heart Rate; Hydrogen-Ion Concentration; Indometha | 1988 |
[Experimental intrauterine growth retardation with indomethacin].
Topics: Animals; Body Weight; Cyclooxygenase Inhibitors; Fasting; Female; Fetal Growth Retardation; Gestatio | 1986 |
Effects of DNA and prostaglandin synthesis inhibitors on the stimulation of bone resorption by epidermal growth factor in fetal rat long-bone cultures.
Topics: Animals; Aphidicolin; Bone Resorption; Diterpenes; DNA Replication; Epidermal Growth Factor; Female; | 1986 |
Cyclooxygenase inhibition reduces placental transfer: reversal by carbacyclin.
Topics: Antipyrine; Cyclooxygenase Inhibitors; Epoprostenol; Female; Humans; Ibuprofen; Indomethacin; Matern | 1987 |
Renal effects of cyclooxygenase inhibition in the pregnant rat.
Topics: Animals; Female; Glomerular Filtration Rate; Indomethacin; Kidney; Pregnancy; Prostaglandin-Endopero | 1987 |
Treatment of polyhydramnios with prostaglandin synthetase inhibitor (indomethacin).
Topics: Adult; Cyclooxygenase Inhibitors; Female; Humans; Indomethacin; Polyhydramnios; Pregnancy; Uterus | 1987 |
Mitogenic action of phorbol ester TPA and calcium ionophore A23187 on human cord and maternal/adult peripheral lymphocytes: regulation by prostaglandin E2.
Topics: Adult; Calcimycin; Cell Division; Dinoprostone; Drug Interactions; Female; Fetal Blood; Humans; Indo | 1987 |
Pulmonary hemodynamics at birth: effect of acute cyclooxygenase inhibition in lambs.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Animals, Newborn; Blood Pressure; Body Temperature; Cardiac O | 1988 |
Acute uteroplacental ischemic embryo: lactic acid accumulation and prostaglandin production in the fetal rat brain.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Benzoquinones; Brain; Cycloox | 1988 |
Characterization of the responses to serotonin and prostanoids in human umbilical arteries perfused in vitro.
Topics: Bridged Bicyclo Compounds, Heterocyclic; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; | 1986 |
The effects of indomethacin administration during pregnancy on women's and newborns' T-suppressor lymphocyte activity and on HLA class II expression by newborns' leukocytes.
Topics: B-Lymphocytes; Female; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Indomethacin; | 1985 |
Postpartum changes in the mechanical responses of the circular muscle of rat uterus.
Topics: Animals; Calcium; Female; Indomethacin; Isotonic Solutions; Magnesium; Muscle, Smooth; Postpartum Pe | 1988 |
Effects of indomethacin on the fetus.
Topics: Ductus Arteriosus; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Tocolytic Ag | 1988 |
Prolonged maternal indomethacin therapy associated with oligohydramnios. Case reports.
Topics: Amniotic Fluid; Female; Fetus; Humans; Indomethacin; Pregnancy; Urination | 1988 |
Renal functional impairment in preterm neonates related to intrauterine indomethacin exposure.
Topics: Female; Humans; Indomethacin; Infant, Newborn; Infant, Premature; Kidney; Pregnancy; Prenatal Exposu | 1988 |
Indomethacin does not diminish the pulmonary vascular response of the fetus to increased oxygen tension.
Topics: Animals; Female; Fetus; Hyperbaric Oxygenation; Indomethacin; Pregnancy; Prostaglandins; Pulmonary C | 1988 |
Indomethacin as an inhibitor of preterm labor. Effect on postnatal renal function.
Topics: Female; Gestational Age; Glomerular Filtration Rate; Humans; Indomethacin; Infant, Newborn; Kidney; | 1988 |
[Immunosuppressive effect of culture supernatant derived from decidual cell rich fraction].
Topics: Cells, Cultured; Chemical Fractionation; Decidua; Female; Humans; Immunity, Cellular; Immunosuppress | 1988 |
Suppression of lymphocyte alloreactivity by early gestational human decidua. II. Characterization of the suppressor mechanisms.
Topics: Antibodies; Concanavalin A; Dinoprostone; Female; Humans; Immune Tolerance; Indomethacin; Interleuki | 1988 |
[The uterine inhibition in the management of premature labor. Comparing the efficiency of various methods].
Topics: Analysis of Variance; Betamethasone; Female; Fenoterol; Humans; Indomethacin; Obstetric Labor, Prema | 1987 |
The significance of prostacyclin produced by pregnant rat myometrium: the relationship between myometrial prostacyclin producing activity and passive stretch of myometrium by growing conceptus.
Topics: Animals; Diestrus; Epoprostenol; Estrus; Female; Indomethacin; Kinetics; Myometrium; Pregnancy; Rats | 1988 |
Influence of short-term indomethacin therapy on fetal urine output.
Topics: Constriction, Pathologic; Diuresis; Ductus Arteriosus; Female; Fetus; Humans; Indomethacin; Obstetri | 1988 |
Immunohistochemical demonstration of prostaglandin E-2 in preimplantation mouse embryos.
Topics: Animals; Blastocyst; Culture Techniques; Dinoprostone; Embryo, Mammalian; Embryonic Development; Fem | 1987 |
Changes in endometrial vascular permeability during the periimplantation period in the ferret (Mustela putorius).
Topics: Animals; Capillary Permeability; Carnivora; Embryo Implantation; Endometrium; Female; Ferrets; Indom | 1988 |
Prolonged maternal indomethacin therapy associated with oligohydramnios. Case reports.
Topics: Adult; Amniotic Fluid; Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy; Pregnanc | 1988 |
Effects of indomethacin on the acid-base balance and hemodynamics of chronically instrumented pregnant sheep.
Topics: Acid-Base Equilibrium; Animals; Blood Pressure; Female; Fetal Monitoring; Fetus; Heart Rate; Hemodyn | 1988 |
Inhibition of the human placental NAD- and NADP-linked 15-hydroxyprostaglandin dehydrogenases by nonsteroidal anti-inflammatory drugs.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hydroxyprostaglandin Dehydrogenases; Indome | 1988 |
Bradykinin-induced vasoconstriction and thromboxane release in perfused human placenta.
Topics: Angiotensin II; Bradykinin; Bridged Bicyclo Compounds, Heterocyclic; Dose-Response Relationship, Dru | 1988 |
Indomethacin in the treatment of premature labor. Effects on the fetal ductus arteriosus.
Topics: Adolescent; Adult; Constriction, Pathologic; Dose-Response Relationship, Drug; Ductus Arteriosus; Ec | 1988 |
Effects of prazosin and indomethacin on the alpha-adrenergic stimulation of rabbit myometrium.
Topics: Animals; Dinoprost; Female; In Vitro Techniques; Indomethacin; Norepinephrine; Prazosin; Pregnancy; | 1988 |
Effect of microsomal leucine aminopeptidase from human placenta (microsomal P-LAP) on pressor response to infused angiotensin II (A-II) in rat.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Humans; Indomethacin; Leucine; Leucyl Aminopeptidas | 1987 |
Effects of indomethacin in utero on the pulmonary vasculature of the newborn guinea pig.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Female; Guinea Pigs; Humans; Indomethacin; Infant, New | 1987 |
Regulation of placental 15-hydroxyprostaglandin dehydrogenase activity by obstetric drugs.
Topics: Actihaemyl; Estrogens; Female; Humans; Hydroxyprostaglandin Dehydrogenases; Indomethacin; Isoxsuprin | 1987 |
The production of pregnancy associated alpha glycoprotein (PAG) from human peripheral blood mononuclear cells.
Topics: Azides; Contraceptives, Oral, Synthetic; Enzyme-Linked Immunosorbent Assay; Ethinyl Estradiol; Femal | 1987 |
[Interceptive action of azastene and its effects on plasma progesterone in pregnant rats and rabbits].
Topics: Abortifacient Agents; Abortifacient Agents, Steroidal; Abortion, Induced; Androstenols; Animals; Car | 1987 |
Involvement of intramural prostaglandin E2 in prenatal patency of the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Dinoprostone; Ductus Arteriosus; Female; Fetus; Glutathione; Indomethacin; | 1986 |
Human platelet-derived transforming growth factor-beta stimulates parameters of bone growth in fetal rat calvariae.
Topics: Animals; Blood Platelets; Bone and Bones; Collagen; DNA Replication; Female; Indomethacin; Osteogene | 1986 |
Aspects of the antiluteolytic activity of the conceptus during early pregnancy in ewes.
Topics: Animals; Corpus Luteum; Dinoprost; Embryo, Mammalian; Estradiol; Female; Indomethacin; Pregnancy; Pr | 1986 |
Decidualization in the rat: role of leukotrienes and prostaglandins.
Topics: Animals; Arachidonic Acids; Chromones; Decidua; Dinoprostone; Female; Hypophysectomy; Indomethacin; | 1987 |
Stimulation of prostaglandin E2 and bone resorption by recombinant human interleukin 1 alpha in fetal mouse bones.
Topics: Animals; Bone and Bones; Bone Resorption; Dinoprostone; Female; Fetus; Hydrocortisone; Indomethacin; | 1986 |
Cardiovascular actions of dihydralazine as modified by dietary linoleic acid.
Topics: Animals; Aorta, Abdominal; Aspirin; Blood Pressure; Dietary Fats; Dihydralazine; Epoprostenol; Fatty | 1986 |
The interaction between serotonin and angiotensin II in the chronically instrumented guinea pig and its alteration by indomethacin.
Topics: Angiotensin II; Animals; Blood Pressure; Bretylium Tosylate; Dose-Response Relationship, Drug; Drug | 1987 |
Safety of indomethacin tocolysis.
Topics: Female; Humans; Indomethacin; Obstetric Labor, Premature; Pregnancy | 1987 |
[Maternal administration of indomethacin and neonatal tricuspid insufficiency].
Topics: Female; Humans; Indomethacin; Infant, Newborn; Male; Obstetric Labor, Premature; Pregnancy; Tricuspi | 1987 |
Net sodium and water movements in the newborn rabbit collecting tubule: lack of modifications by indomethacin.
Topics: Animals; Animals, Newborn; Body Water; Electric Conductivity; Female; Indomethacin; Kidney Tubules; | 1987 |
Inhibition of premature labour with indomethacin.
Topics: Female; Fetal Membranes, Premature Rupture; Humans; Indomethacin; Infant, Low Birth Weight; Infant, | 1987 |
Effect of indomethacin on alcohol-induced morphological anomalies in mice.
Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Ethanol; Female; Fertility; Fetal Death; Indometh | 1987 |
Effect of hepatic cytosol on postnatal drug metabolism.
Topics: Animals; Animals, Newborn; Cytosol; Female; Indomethacin; Liver; Male; Microsomes, Liver; Mixed Func | 1987 |
Effects of maternal indomethacin administration on fetal breathing movements in sheep.
Topics: Animals; Blood Glucose; Carotid Arteries; Female; Fetal Movement; Indomethacin; Kinetics; Maternal-F | 1987 |
The effect of acetylsalicylic acid and indomethacin on the catecholamine- and oxytocin-induced contractility and prostaglandin (6-keto-PGF1 alpha, PGF2 alpha)-production of human pregnant myometrial strips.
Topics: Aspirin; Epinephrine; Female; Humans; In Vitro Techniques; Indomethacin; Myometrium; Oxytocin; Pregn | 1987 |
[Harmful action of indomethacin on the fetus].
Topics: Abnormalities, Drug-Induced; Female; Fetus; Humans; Indomethacin; Infant, Newborn; Pregnancy; Pregna | 1987 |
In vivo constriction of the ductus arteriosus by nonsteroidal antiinflammatory drugs in near-term and preterm fetal rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Ductus Arteriosu | 1987 |
Management of preterm labor and delivery.
Topics: Adrenal Cortex Hormones; Anesthesia, Conduction; Calcium Channel Blockers; Cesarean Section; Deliver | 1986 |
Obstetric management of the very low birth weight fetus.
Topics: Adrenal Cortex Hormones; Extraction, Obstetrical; Female; Fetal Distress; Fetal Monitoring; Fetal Or | 1986 |
Neonatal outcome after indomethacin treatment for preterm labor.
Topics: Apgar Score; Birth Weight; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn, Diseases; | 1986 |
Premature closure of the ductus arteriosus causing intra-uterine death. A case report.
Topics: Adult; Ductus Arteriosus; Edema; Female; Fetal Death; Humans; Indomethacin; Obstetric Labor, Prematu | 1986 |
Constriction of the fetal ductus arteriosus by progesterone.
Topics: Animals; Ductus Arteriosus; Female; Fetus; Indomethacin; Pregnancy; Progesterone; Rats; Rats, Inbred | 1986 |
Detection and quantitation of constriction of the fetal ductus arteriosus by Doppler echocardiography.
Topics: Animals; Constriction, Pathologic; Ductus Arteriosus; Echocardiography; Female; Fetal Diseases; Huma | 1987 |
Intrauterine exposure to indomethacin.
Topics: Female; Humans; Indomethacin; Infant, Newborn; Kidney Failure, Chronic; Male; Maternal-Fetal Exchang | 1986 |
[The effect of indomethacin on the implantation and metabolism of blastocysts].
Topics: Animals; Blastomeres; Cells, Cultured; Dinoprost; Embryo Implantation; Female; Indomethacin; Male; M | 1985 |
Prostaglandins involvement in the formation of luteinized unruptured follicles in the cyclic female rat.
Topics: Animals; Diestrus; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Female; Indomethacin; | 1985 |
Aminoglycoside treatment and renal prostaglandin excretion in premature infants.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Creatinine; Dinoprost; Dinoprostone; Ductus Arteriosu | 1985 |
Estrogen effects on sister chromatid exchanges in mouse uterine cervical and kidney cells.
Topics: Animals; Benzoflavones; Cells, Cultured; Cervix Uteri; Diethylstilbestrol; Dose-Response Relationshi | 1985 |
Effect of PGF2 alpha administration on the release of endogenous PGF2 alpha and oxytocin in indomethacin-treated goats.
Topics: Animals; Dinoprost; Estrus; Female; Goats; Indomethacin; Luteal Phase; Luteolysis; Ovary; Oxytocin; | 1985 |
Fetal stimulation of maternal immunoglobulin production in mice.
Topics: Animals; Dinoprost; Dinoprostone; Female; Fetus; Immunoglobulin G; Immunoglobulin M; Immunoglobulins | 1985 |
[Effects of indomethacin, prostaglandin E2 and prostaglandin F2 alpha on hatching of mouse blastocysts].
Topics: Animals; Arachidonic Acids; Blastocyst; Cells, Cultured; Dinoprost; Dinoprostone; Dose-Response Rela | 1985 |
Hemodynamic effects of indomethacin in chronically instrumented pregnant sheep.
Topics: Animals; Cardiac Output; Female; Hemodynamics; Indomethacin; Placenta; Pregnancy; Pregnancy, Animal; | 1985 |
Prostaglandins and fetal cardiac output distribution in the lamb.
Topics: Animals; Cardiac Output; Dinoprostone; Dose-Response Relationship, Drug; Ductus Arteriosus; Epoprost | 1985 |
Effects of angiotensin I and II and their interactions with some prostanoids in perfused human umbilical arteries.
Topics: Angiotensin I; Angiotensin II; Angiotensins; Captopril; Drug Interactions; Female; Humans; In Vitro | 1985 |
Ascorbate-dependent lipid peroxidation in the human placenta and fetal membranes.
Topics: Amnion; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Chorion; Female; Humans; Indomethacin; L | 1985 |
Preeclampsia: an imbalance in placental prostacyclin and thromboxane production.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Arachidonic Acid; Arachidonic Acids; Culture Media; Epoprosteno | 1985 |
Stimulation of ovine placental lactogen secretion by arachidonic acid.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Female; Fetal Blood; Gestational Age; Ibuprofen; Indom | 1985 |
Evidence for an inverse relationship between cyclooxygenase and lipoxygenase pathways in the pregnant rabbit endometrium.
Topics: Animals; Arachidonate Lipoxygenases; Catechols; Endometrium; Female; Indomethacin; Lipoxygenase; Mas | 1985 |
Arachidonic acid and isolated human umbilical vein: concentration-limited prostacyclin generation and absence of direct toxic effects on endothelial integrity.
Topics: Arachidonic Acid; Arachidonic Acids; Cyclooxygenase Inhibitors; Endothelium; Epoprostenol; Female; H | 1985 |
Metabolism of arachidonic acid in vitro by ovine conceptuses recovered during early pregnancy.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Blastocyst; Endometrium; Female; Gestational Age; In V | 1985 |
The mechanism of the inhibitory effect of progesterone on lymphocyte cytotoxicity: II. Relationship between cytotoxicity and the cyclooxygenase pathway of arachidonic acid metabolism.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Anti-Inflammatory Agents; Arachidonic | 1985 |
Evidence against the hypothesis that prostaglandins are the vasodepressor agents of pregnancy. Serial studies in chronically instrumented, conscious rats.
Topics: Angiotensin II; Animals; Blood Pressure; Female; Glomerular Filtration Rate; Hemodynamics; Indometha | 1986 |
Effects of renal denervation on renal responses to hypoxemia in fetal lambs.
Topics: Animals; Blood Pressure; Chlorides; Denervation; Female; Glomerular Filtration Rate; Hemodynamics; H | 1986 |
Indomethacin inhibits the uptake of 22sodium by ovine trophoblastic tissue in vitro.
Topics: Animals; Biological Transport, Active; Blastocyst; Female; In Vitro Techniques; Indomethacin; Kineti | 1986 |
Role of prostaglandins in development of porcine blastocysts.
Topics: Animals; Blastocyst; Clonixin; Female; Hysterectomy; Indomethacin; Nicotinic Acids; Pregnancy; Prost | 1986 |
Fetal and neonatal effects of indomethacin used as a tocolytic agent.
Topics: Birth Weight; Female; Fetus; Humans; Indomethacin; Infant Mortality; Infant, Newborn; Infant, Newbor | 1985 |
Hormonal control of gap junctions in the myometrium.
Topics: Animals; Castration; Diethylstilbestrol; Estradiol; Female; Freeze Fracturing; Indomethacin; Interce | 1985 |
The influence of prostaglandin E2 and oxytocin on the incorporation of [3H]proline and [3H]glucosamine in the human amnion.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Amnion; Connective Tissue; Female; Glucosamine; Humans; Indomethaci | 1985 |
Characteristic morphology of the constricted fetal ductus arteriosus following maternal administration of indomethacin.
Topics: Animals; Animals, Newborn; Ductus Arteriosus; Female; Fetus; Indomethacin; Pregnancy; Pregnancy, Ani | 1985 |
Side effects of indomethacin.
Topics: Animals; Female; Fetus; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy | 1985 |
Catecholamines and contractility of the human myometrium at term: a possible role for prostaglandins.
Topics: Arachidonic Acids; Catecholamines; Dopamine; Epinephrine; Female; Humans; Indomethacin; Labor, Obste | 1985 |
Structural and functional studies of myometrial gap junctions.
Topics: Animals; Castration; Deoxyglucose; Electric Conductivity; Estradiol; Female; Indomethacin; Intercell | 1985 |
Suppression of leukocytosis by the intrauterine delivery of high doses of indomethacin in the rat.
Topics: Animals; Anti-Inflammatory Agents; Biological Availability; Drug Implants; Female; Indomethacin; Leu | 1985 |
Determination of certain physical and chemical characteristics of the activating serum factor from preparturient women and women with habitual abortions.
Topics: Abortion, Habitual; Animals; Female; Glycoproteins; Humans; Indomethacin; Labor, Obstetric; Molecula | 1985 |
Inhibition of pregnancy with indomethacin in mature gilts and prepuberal gilts induced to ovulate.
Topics: Animals; Corpus Luteum Maintenance; Dinoprost; Female; Gonadotropins, Equine; Indomethacin; Ovulatio | 1985 |
Inhibition of bovine luteal function by indomethacin.
Topics: Animals; Cattle; Corpus Luteum; Drug Interactions; Estrus; Female; Indomethacin; Oxytocin; Pregnancy | 1985 |
Sow (Sus scrofa) follicular fluid: prostaglandin content and effect on the motility of isolated oviducts.
Topics: Animals; Bradykinin; Estrus; Fallopian Tubes; Female; Indomethacin; Muscle Contraction; Ovarian Foll | 1985 |
Influence of ovarian steroids on prostaglandin- and leukotriene-induced uterine contractions.
Topics: Animals; Castration; Chromones; Estradiol; Estrus; Female; Guinea Pigs; Indomethacin; Methapyrilene; | 1985 |
The effect of indomethacin on breathing movements and cerebral blood flow and metabolism in the fetal sheep.
Topics: Animals; Blood Pressure; Brain; Cerebral Cortex; Cerebrovascular Circulation; Electroencephalography | 1985 |
Nonsteroidal anti-inflammatory agents. A review of the literature.
Topics: Absorption; Anti-Inflammatory Agents; Aspirin; Diflunisal; Drug Interactions; Female; Fenoprofen; Ha | 1985 |
Fetal and neonatal effects of indomethacin used as a tocolytic agent.
Topics: Female; Fetus; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy | 1985 |
Evidence for the involvement of prostaglandins throughout the decidual cell reaction in the rat.
Topics: Animals; Decidua; Dose-Response Relationship, Drug; Female; Indomethacin; Pregnancy; Prostaglandins | 1985 |
Progesterone and oestradiol receptor concentration and translocation in uterine tissue of rabbits treated with indomethacin.
Topics: Animals; Cell Nucleus; Cytosol; Endometrium; Estradiol; Female; Indomethacin; Pregnancy; Progesteron | 1985 |
Fetal and neonatal effects of indomethacin used as a tocolytic agent.
Topics: Female; Fetus; Humans; Indomethacin; Infant, Newborn; Obstetric Labor, Premature; Pregnancy | 1985 |
Inhibition by indomethacin of increased estradiol extraction by the IUD-containing rat uterine horn.
Topics: Animals; Diestrus; Estradiol; Female; Indomethacin; Intrauterine Devices; Ovariectomy; Pregnancy; Pr | 1985 |
Inhibition of prostaglandin release and the control of threatened abortion.
Topics: Abortion, Threatened; Aspirin; Blood Platelets; Female; Humans; Indomethacin; Lung; Obstetric Labor | 1971 |
Letter: Inhibitors of prostaglandin synthesis and fetal development.
Topics: Animals; Cell Differentiation; Female; Fetal Death; Fetus; Gestational Age; Indomethacin; Mice; Preg | 1974 |
Prostaglandin synthesis by the pregnant rat uterus at term and its possible relevance in parturition.
Topics: Animals; Endometrium; Female; In Vitro Techniques; Indomethacin; Labor, Obstetric; Pregnancy; Prosta | 1973 |
Block of oxytocin-induced parturition and oviposition by prostaglandin inhibitors.
Topics: Administration, Oral; Animals; Catheterization; Fatty Acids, Unsaturated; Female; Indomethacin; Labo | 1973 |
Indomethacin block of normal onset of parturition in primates.
Topics: Administration, Oral; Animals; Cesarean Section; Delivery, Obstetric; Female; Fetus; Gestational Age | 1974 |
Pregnancy blockade by indomethacin, an inhibitor of prostaglandin synthesis: its reversal by prostaglandins and progesterone in mice.
Topics: Animals; Depression, Chemical; Embryo Implantation; Female; Indomethacin; Injections, Subcutaneous; | 1973 |
Editorial: Prostaglandins--tour d'horizon.
Topics: Abortion, Induced; Aspirin; Female; Humans; Indomethacin; Kidney; Natriuresis; Phenylbutazone; Pregn | 1974 |
Ovulation block by indomethacin, an inhibitor of prostaglandin synthesis: a study of its site of action in rats.
Topics: Animals; Chorionic Gonadotropin; Estrus; Female; Follicle Stimulating Hormone; Gonadotropins, Equine | 1974 |
Interruption of pregnancy by various steroids.
Topics: Abortion, Induced; Anabolic Agents; Animals; Cholesterol; Dehydroepiandrosterone; Dexamethasone; Dig | 1971 |
The effect of angiotensin-II intravenous infusion on plasma renin activity and prostaglandins A, E, and F levels in the uterine vein of the pregnant monkey.
Topics: Alanine; Angiotensin II; Animals; Blood Pressure; Depression, Chemical; Female; Glucose; Haplorhini; | 1974 |
Prostaglandin F production in vitro by granulosa cells from rabbit pre-ovulatory follicles.
Topics: Animals; Bucladesine; Cells, Cultured; Culture Media; Estrus; Female; Follicle Stimulating Hormone; | 1974 |
Proceedings: Influence of postaglandins and oestrus cycle on the spasmodic action of angiotensin II and oxytocin on rat uterus.
Topics: Angiotensin II; Animals; Dose-Response Relationship, Drug; Estrus; Female; In Vitro Techniques; Indo | 1974 |
Effects of prostaglandin inhibitors on angiotensin, oxytocin and prostaglandin F2 alpha contractile effects on the rat uterus during the oestrous cycle.
Topics: Angiotensin II; Animals; Estrus; Female; In Vitro Techniques; Indomethacin; Muscle Contraction; Oxyt | 1974 |
Prostaglandin E - angiotensin II interactions in the gravid uterus.
Topics: Angiotensin II; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Drug Interactions; Female; Indom | 1974 |
The effect of anti-inflammatory drugs on the protein-binding of 11-hydroxysteroids in human plasma in vitro.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1969 |
The effect of endogenous and exogenous estradiol-17beta on the release of prostaglandin F2alpha from the ovine uterus.
Topics: Animals; Estradiol; Estrus; Female; Indomethacin; Injections, Intra-Arterial; Luteinizing Hormone; P | 1974 |
Inhibition of human premature labor by indomethacin.
Topics: Adolescent; Adult; Blood Pressure; Depression, Chemical; Extraembryonic Membranes; Female; Fetal Hea | 1974 |
Studies on closure of the ductus arteriosus. XI. Ductal closure in utero by a prostaglandin synthetase inhibitor.
Topics: Animals; Blood; Carbon Dioxide; Cyanosis; Ductus Arteriosus; Female; Fetus; Hydrogen-Ion Concentrati | 1974 |
Inhibitors of prostaglandin synthesis during pregnancy. 1. Embryopathic activity of indomethacin in mice.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetal Diseases; Fetus; Gestational Age; I | 1974 |
Inhibitors of prostaglandin synthesis during pregnancy. 2. The effects of indomethacin in pregnant rats.
Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetal Diseases; Fetus; Growth; Indomethac | 1974 |
Regulation of uterine activity during gestation and parturition in rabbits and rats.
Topics: Animals; Estradiol; Estrogens; Estrone; Female; Indomethacin; Muscle Contraction; Muscle, Smooth; Ov | 1974 |
The blockade of LH release by indomethacin.
Topics: Animals; Contraceptive Agents; Estradiol; Estrus; Female; Hypothalamo-Hypophyseal System; Indomethac | 1974 |
Prostaglandins F and ovulation in mice.
Topics: Animals; Estrus; Fallopian Tubes; Female; Immune Sera; Indomethacin; Mice; Ovulation; Ovum; Pregnanc | 1974 |
Mechanism of ulcerogenic activity of indomethacin and oxyphenbutazone.
Topics: Adrenal Glands; Adrenalectomy; Animals; Atropine; Cordotomy; Dose-Response Relationship, Drug; Femal | 1973 |
[Anti-inflammatory agents in dentistry].
Topics: Adult; Anti-Inflammatory Agents; Chymotrypsin; Edema; Female; Fluphenazine; Humans; Indomethacin; In | 1974 |
Naproxen. Proceedings from an International Medical Symposium presented by Syntex Corporation 7-8 May 1973, Geneva, Switzerland.
Topics: Adolescent; Adult; Aged; Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspir | 1973 |
Letter to the editor: Non steroid anti-inflammatory drugs and pregnancy.
Topics: Anti-Inflammatory Agents; Aspirin; Blood Platelets; Female; Fetus; Homeostasis; Humans; Indomethacin | 1974 |
Prostaglandin mediated luteolytic effect of an intrauterine device in sheep.
Topics: Animals; Corpus Luteum; Depression, Chemical; Endometrium; Estrus; Female; Foreign-Body Reaction; In | 1972 |
Aspirin and indomethacin prolong parturition in rats: evidence that prostaglandins contribute to expulsion of fetus.
Topics: Administration, Oral; Animals; Aspirin; Biological Assay; Chickens; Chromatography, Thin Layer; Fema | 1972 |
Delay of parturition in the rat by anti-inflammatory agents which inhibit the biosynthesis of prostaglandins.
Topics: Acetates; Administration, Oral; Animals; Anti-Inflammatory Agents; Aspirin; Cortisone; Depression, C | 1972 |
Physiological role of prostaglandins in the induction of ovulation.
Topics: Animals; Depression, Chemical; Estrus; Female; Indomethacin; Injections, Intraperitoneal; Luteinizin | 1972 |
Pregnancy in a patient after cadaveric renal transplantation.
Topics: Adult; Agglutinins; Azathioprine; Biopsy; Blood Pressure; Cadaver; Estrogens; Female; Graft Rejectio | 1973 |
An attempt to inhibit the uterine luteolysin in the guinea-pig.
Topics: Animals; Corpus Luteum; Estrus; Female; Guinea Pigs; Indomethacin; Pregnancy; Prostaglandin Antagoni | 1972 |
Development and application of a radioimmunoassay for F prostaglandins.
Topics: Animals; Antibody Specificity; Chromatography; Corpus Luteum; Estradiol; Estrus; Female; Haplorhini; | 1972 |
Mid-trimester hypertonic saline--induced abortion: effect of indomethacin on induction-abortion time.
Topics: Abortion, Induced; Female; Gestational Age; Humans; Hypertonic Solutions; Indomethacin; Pregnancy; P | 1972 |
Blockade of spontaneous and LH-induced ovulation in rats by indomethacin, an inhibitor of prostaglandin biosynthesis. I.
Topics: Animals; Corpus Luteum; Depression, Chemical; Estrus; Female; Gonadotropins, Equine; Indomethacin; L | 1972 |
Relationship between endotoxin-induced abortion and the synthesis of prostaglandin F.
Topics: Abortion, Induced; Animals; Diarrhea; Dose-Response Relationship, Drug; Drug Interactions; Endotoxin | 1972 |
The effects of an inhibitor of prostaglandin synthesis (indomethacin) on ovulation, pregnancy, and pseudopregnancy in the rabbit.
Topics: Animals; Chorionic Gonadotropin; Coitus; Corpus Luteum; Depression, Chemical; Female; Fetal Diseases | 1972 |
Aspirin and indomethacin: effect on instillation-abortion time of mid-trimester hypertonic saline induced abortion.
Topics: Abortion, Induced; Adult; Amniotic Fluid; Aspirin; Depression, Chemical; Drug Interactions; Female; | 1973 |
[Pharmacokinetics of indomethacin in pregnant and parturient women and in their newborn infants].
Topics: Adult; Blood; Female; Gestational Age; Humans; Indomethacin; Infant, Newborn; Labor, Obstetric; Mate | 1973 |
Ovulation rate and serum LH levels in rats treated with indomethacin or prostaglandin E2.
Topics: Animals; Depression, Chemical; Estrus; Female; Indomethacin; Injections, Intraperitoneal; Injections | 1973 |
Indomethacin lengthens the oestrous cycle of the guinea-pig when given orally with oestrogen or when implanted within the uterine lumen.
Topics: Administration, Oral; Animals; Corpus Luteum; Delayed-Action Preparations; Estradiol; Estrogens; Est | 1973 |
The contribution of prostaglandin production to contractions of the isolated uterus of the rat.
Topics: Animals; Chromatography, Gas; Ducks; Epinephrine; Female; In Vitro Techniques; Indomethacin; Muscle | 1973 |
[Transient osteoporosis of the hip joint].
Topics: Adult; Female; Hip Joint; Humans; Indomethacin; Osteoporosis; Pregnancy; Pregnancy Complications; Ti | 1973 |
Prostaglandin release from the human umbilical artery in vitro.
Topics: Depression, Chemical; Female; Humans; In Vitro Techniques; Indomethacin; Methods; Pregnancy; Prostag | 1973 |
Elongation of oestrous cycle in the guinea-pig following subcutaneous or intra-uterine administration of indomethacin.
Topics: Animals; Chromatography, Gas; Corpus Luteum; Delayed-Action Preparations; Depression, Chemical; Estr | 1973 |
The role of prostaglandin in endotoxin-induced abortion and fetal death.
Topics: Abortion, Induced; Animals; Cyproheptadine; Depression, Chemical; Endotoxins; Female; Fetal Death; H | 1973 |
The formation of prostaglandins by the guinea-pig uterus and the effect of indomethacin.
Topics: Animals; Estrus; Female; Guinea Pigs; Indomethacin; Pregnancy; Prostaglandins; Prostaglandins E; Pro | 1973 |
Induction of 20 alpha-hydroxysteroid dehydrogenase in rat corpora lutea of pregnancy by prostaglandin F-2 alpha.
Topics: Animals; Chorionic Gonadotropin; Corpus Luteum; Enzyme Induction; Estradiol; Female; Follicle Stimul | 1974 |
Prostaglandin F in the uterine horns of mice with intrauterine devices.
Topics: Animals; Female; Indomethacin; Injections, Subcutaneous; Intrauterine Devices; Mice; Pregnancy; Pros | 1974 |
Effect of IUDs, prostaglandins and indomethacin on decidual cell reaction in the rat.
Topics: Animals; Decidua; Depression, Chemical; Female; Indomethacin; Intrauterine Devices; Organ Size; Ovar | 1974 |
Prostaglandin-mediated action of intrauterine devices: F-prostaglandins in the uterine horns of pregnant rabbits with unilateral intrauterine devices.
Topics: Animals; Corpus Luteum; Embryo Implantation; Female; Indomethacin; Injections, Subcutaneous; Intraut | 1974 |
Cyclic changes in the uterine tissue content of F-prostaglandins and the role of prostaglandins in ovulation in mice.
Topics: Animals; Arachidonic Acids; Estradiol; Estrogens; Estrus; Female; Freeze Drying; Indomethacin; Mice; | 1974 |
Unremitting disease in a young mother.
Topics: Adult; Arthritis, Rheumatoid; Depression; Female; Humans; Indomethacin; Osteoporosis; Phenylbutazone | 1972 |
Production of prostaglandins by the guinea-pig uterus.
Topics: Animals; Chromatography, Gas; Depression, Chemical; Estrus; Female; Guinea Pigs; Indomethacin; Mass | 1972 |
[Toxicologic study of methiazinic acid (16091 R.P)].
Topics: Abnormalities, Drug-Induced; Acetates; Anemia; Animals; Dogs; Drug Tolerance; Female; Gastric Mucosa | 1969 |
Mode of action of antirheumatic drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Bilirubin; Binding Sites; Blood Proteins; Chloroquine; | 1971 |
Current trends in therapy of rheumatoid conditions.
Topics: Adolescent; Adult; Animals; Arthritis, Juvenile; Arthritis, Rheumatoid; Cardiovascular System; Centr | 1965 |