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indomethacin and Postpericardiotomy Syndrome

indomethacin has been researched along with Postpericardiotomy Syndrome in 5 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Postpericardiotomy Syndrome: A nonspecific hypersensitivity reaction caused by TRAUMA to the PERICARDIUM, often following PERICARDIOTOMY. It is characterized by PERICARDIAL EFFUSION; high titers of anti-heart antibodies; low-grade FEVER; LETHARGY; loss of APPETITE; or ABDOMINAL PAIN.

Research Excerpts

ExcerptRelevanceReference
"Although the postpericardiotomy syndrome is a common complication of cardiac operations, the most effective drug regimen for the treatment of this condition has not been established."2.67The effective treatment of postpericardiotomy syndrome after cardiac operations. A randomized placebo-controlled trial. ( Gardner, TJ; Horneffer, PJ; Miller, RH; Pearson, TA; Reitz, BA; Rykiel, MF, 1990)
"Postpericardiotomy syndrome is diagnosed after excluding other conditions such as endocarditis and pneumonia."2.37Postpericardiotomy syndrome. ( Clark, EB; Leff, RD; McClendon, CE, 1986)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's2 (40.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Giacinto, O1
Minati, A1
Lusini, M1
Cardetta, F1
Saltarocchi, S1
D'Abramo, M1
Miraldi, F1
Chello, M1
Bartels, C1
Hönig, R1
Burger, G1
Diehl, V1
de Vivie, R1
Livelli, FD1
Johnson, RA1
McEnany, MT1
Sherman, E1
Newell, J1
Block, PC1
DeSanctis, RW1
Horneffer, PJ1
Miller, RH1
Pearson, TA1
Rykiel, MF1
Reitz, BA1
Gardner, TJ1
McClendon, CE1
Leff, RD1
Clark, EB1

Reviews

2 reviews available for indomethacin and Postpericardiotomy Syndrome

ArticleYear
Treatment and Prophylaxis of Post-pericardiotomy Syndrome in Cardiac Surgery Patients: a Systematic Review.
    Cardiovascular drugs and therapy, 2023, Volume: 37, Issue:4

    Topics: Cardiac Surgical Procedures; Colchicine; Dexamethasone; Humans; Indomethacin; Pericardiectomy; Postp

2023
Postpericardiotomy syndrome.
    Drug intelligence & clinical pharmacy, 1986, Volume: 20, Issue:1

    Topics: Analgesics; Anti-Inflammatory Agents; Diuretics; Heart Diseases; Humans; Indomethacin; Postpericardi

1986

Trials

2 trials available for indomethacin and Postpericardiotomy Syndrome

ArticleYear
Unexplained in-hospital fever following cardiac surgery. Natural history, relationship to postpericardiotomy syndrome, and a prospective study of therapy with indomethacin versus placebo.
    Circulation, 1978, Volume: 57, Issue:5

    Topics: Cardiac Surgical Procedures; Clinical Trials as Topic; Cross Infection; Double-Blind Method; Fever;

1978
The effective treatment of postpericardiotomy syndrome after cardiac operations. A randomized placebo-controlled trial.
    The Journal of thoracic and cardiovascular surgery, 1990, Volume: 100, Issue:2

    Topics: Cardiac Surgical Procedures; Double-Blind Method; Female; Heart Diseases; Humans; Ibuprofen; Indomet

1990

Other Studies

1 other study available for indomethacin and Postpericardiotomy Syndrome

ArticleYear
The significance of anticardiolipin antibodies and anti-heart muscle antibodies for the diagnosis of postpericardiotomy syndrome.
    European heart journal, 1994, Volume: 15, Issue:11

    Topics: Aged; Antibodies, Anticardiolipin; Autoantibodies; C-Reactive Protein; Double-Blind Method; Enzyme-L

1994