Page last updated: 2024-10-29

indomethacin and Polycythemia Vera

indomethacin has been researched along with Polycythemia Vera in 4 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Polycythemia Vera: A myeloproliferative disorder of unknown etiology, characterized by abnormal proliferation of all hematopoietic bone marrow elements and an absolute increase in red cell mass and total blood volume, associated frequently with splenomegaly, leukocytosis, and thrombocythemia. Hematopoiesis is also reactive in extramedullary sites (liver and spleen). In time myelofibrosis occurs.

Research Excerpts

ExcerptRelevanceReference
"Erythromelalgia was localized in the forefoot sole and toes in 28, the fingertips in 9, the handpalm in 2."2.39Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia. ( Lindemans, J; Michiels, JJ; van Genderen, PJ; van Vliet, HH, 1996)
"Erythromelalgia was the presenting symptom in 26 of 40 patients with thrombocythemia in its primary form or when associated with polycythemia vera."1.27Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia. ( Abels, J; Michiels, JJ; Steketee, J; van Vliet, HH; Vuzevski, VD, 1985)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19903 (75.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Michiels, JJ2
van Genderen, PJ1
Lindemans, J1
van Vliet, HH2
Kurihara, A1
Kobayashi, I1
Tamura, K1
Abels, J1
Steketee, J1
Vuzevski, VD1
Treske, U1

Reviews

1 review available for indomethacin and Polycythemia Vera

ArticleYear
Erythromelalgic, thrombotic and hemorrhagic manifestations in 50 cases of thrombocythemia.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Aspirin; Busulfan; Double-Blind Method; Erythromelalgia; Female; Gangrene; Hemorrhage;

1996

Other Studies

3 other studies available for indomethacin and Polycythemia Vera

ArticleYear
[Clinical evaluation of the control of antiplatelet therapy through platelet aggregation rate on polycythemia vera associated with thrombocytosis and erythromelalgia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 1989, Volume: 30, Issue:1

    Topics: Aspirin; Drug Evaluation; Erythromelalgia; Female; Fingers; Humans; Indomethacin; Middle Aged; Plate

1989
Erythromelalgia caused by platelet-mediated arteriolar inflammation and thrombosis in thrombocythemia.
    Annals of internal medicine, 1985, Volume: 102, Issue:4

    Topics: Adult; Aged; Analgesics; Arteries; Arterioles; Arteritis; Aspirin; Blood Platelets; Erythromelalgia;

1985
[Indomethacin and hematopoiesis. Antipyretic and antiphlogistic effects in hemoblastoses and various uncommon diseases].
    Medizinische Klinik, 1968, Mar-01, Volume: 63, Issue:9

    Topics: Arthritis, Infectious; Arthritis, Rheumatoid; Dermatomyositis; Female; Hematologic Diseases; Hematop

1968