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indomethacin and Pneumonia

indomethacin has been researched along with Pneumonia in 16 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Pneumonia: Infection of the lung often accompanied by inflammation.

Research Excerpts

ExcerptRelevanceReference
"The effect of indomethacin (1 mg/kg) on gas exchange was studied in ten patients with hypoxaemic respiratory failure precipitated by bacterial pneumonia."7.67Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia. ( Dobson, K; Hanly, PJ; Light, RB; Roberts, D, 1987)
" Low-dose indomethacin combined with methylprednisolone may be a new choice for AFOP treatment."6.53Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review. ( Bian, LJ; Chen, M; Chen, QK; Huang, LJ; Jiang, SP; Lin, XL; Tang, TT; Zhou, CX, 2016)
"The effect of indomethacin (1 mg/kg) on gas exchange was studied in ten patients with hypoxaemic respiratory failure precipitated by bacterial pneumonia."3.67Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia. ( Dobson, K; Hanly, PJ; Light, RB; Roberts, D, 1987)
"Acute bilateral Pseudomonas aeruginosa pneumonia was induced in 10 anesthetized dogs, after which five dogs received intravenous indomethacin (2 mg/kg) (indomethacin group), whereas five others were infused with saline (2 ml/kg) (control group)."3.67Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia. ( Hanly, P; Light, RB; Sienko, A, 1987)
" Low-dose indomethacin combined with methylprednisolone may be a new choice for AFOP treatment."2.53Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review. ( Bian, LJ; Chen, M; Chen, QK; Huang, LJ; Jiang, SP; Lin, XL; Tang, TT; Zhou, CX, 2016)
" The 5-lipoxygenase inhibitor diethylcarbamazine and the LTD4/LTE4 receptor antagonist LY 171883 markedly reduced mortality in dose-response fashion."1.28Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis. ( Gross, NJ; Holloway, NO; Narine, KR, 1991)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's4 (25.00)18.2507
2000's2 (12.50)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Zhou, W1
Zhang, J1
Toki, S1
Goleniewska, K1
Norlander, AE1
Newcomb, DC1
Wu, P1
Boyd, KL1
Kita, H1
Peebles, RS1
Kao, RL1
Huang, W1
Martin, CM1
Rui, T1
Zhou, CX1
Tang, TT1
Huang, LJ1
Lin, XL1
Chen, M1
Bian, LJ1
Chen, QK1
Jiang, SP1
Castro, P1
Nasser, H1
Abrahão, A1
Dos Reis, LC1
Riça, I1
Valença, SS1
Rezende, DC1
Quintas, LE1
Cavalcante, MC1
Porto, LC1
Koatz, VL1
Hunte, TC1
Bernstein, HM1
Dickinson, GM1
Dotsenko, IaN1
Shekhovtseva, TG1
Simochkina, EA1
Steil, AA1
Tavares de Lima, W1
Jancar, S1
Melton, SM1
Davis, KA1
Moomey, CB1
Fabian, TC1
Proctor, KG1
Vancheri, C1
Mastruzzo, C1
Tomaselli, V1
Sortino, MA1
D'Amico, L1
Bellistrí, G1
Pistorio, MP1
Salinaro, ET1
Palermo, F1
Mistretta, A1
Crimi, N1
Kleeberger, SR1
Hudak, BB1
Gross, NJ1
Holloway, NO1
Narine, KR1
Hanly, PJ1
Roberts, D1
Dobson, K1
Light, RB2
Bihari, DJ1
Meyrick, B1
Perkett, EA1
Brigham, KL1
Hanly, P1
Sienko, A1
Stenmark, KR1
Morganroth, ML1
Remigio, LK1
Voelkel, NF1
Murphy, RC1
Henson, PM1
Mathias, MM1
Reeves, JT1

Reviews

1 review available for indomethacin and Pneumonia

ArticleYear
Methylprednisolone combined with low-dose indomethacin treating acute fibrinous and organizing pneumonia after a surgical resection of rectal adenocarcinoma: a case report and literature review.
    European review for medical and pharmacological sciences, 2016, Volume: 20, Issue:10

    Topics: Adenocarcinoma; Anti-Inflammatory Agents; Cross Infection; Female; Humans; Indomethacin; Methylpredn

2016

Other Studies

15 other studies available for indomethacin and Pneumonia

ArticleYear
COX Inhibition Increases
    Journal of immunology (Baltimore, Md. : 1950), 2020, 08-15, Volume: 205, Issue:4

    Topics: Allergens; Alternaria; Alternariosis; Animals; Bronchoalveolar Lavage Fluid; Cell Proliferation; Cyc

2020
The effect of aerosolized indomethacin on lung inflammation and injury in a rat model of blunt chest trauma
    Canadian journal of surgery. Journal canadien de chirurgie, 2018, 12-01, Volume: 61, Issue:6

    Topics: Acute Lung Injury; Administration, Inhalation; Aerosols; Animals; Anti-Inflammatory Agents, Non-Ster

2018
Aspirin and indomethacin reduce lung inflammation of mice exposed to cigarette smoke.
    Biochemical pharmacology, 2009, Mar-15, Volume: 77, Issue:6

    Topics: Animals; Aspirin; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Indomethacin; Male

2009
Acute crystalline arthritis in an artificial knee.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2012, Volume: 18, Issue:4

    Topics: Acute Disease; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replace

2012
[Indomethacin in the treatment of acute pneumonia].
    Vrachebnoe delo, 1984, Issue:6

    Topics: Acute Disease; Adolescent; Adult; Female; Humans; Indomethacin; Male; Middle Aged; Pneumonia

1984
Modulation by lipid mediators of immune complex-induced lung inflammation in mice.
    European journal of pharmacology, 1998, Nov-13, Volume: 361, Issue:1

    Topics: Animals; Antigen-Antibody Complex; Arthus Reaction; Azepines; Benzopyrans; Blood Vessels; Bronchoalv

1998
Mediator-dependent secondary injury after unilateral blunt thoracic trauma.
    Shock (Augusta, Ga.), 1999, Volume: 11, Issue:6

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blood Transfusion; Cerebrovascular Disorders; Cont

1999
Normal human lung fibroblasts differently modulate interleukin-10 and interleukin-12 production by monocytes: implications for an altered immune response in pulmonary chronic inflammation.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:5

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; CD40 Antigens; Cell Communication; Cells, Cultured;

2001
Acute ozone-induced change in airway permeability: role of infiltrating leukocytes.
    Journal of applied physiology (Bethesda, Md. : 1985), 1992, Volume: 72, Issue:2

    Topics: Animals; Bronchoalveolar Lavage Fluid; Colchicine; Cyclophosphamide; Indomethacin; Lung; Lung Injury

1992
Effects of some nonsteroidal anti-inflammatory agents on experimental radiation pneumonitis.
    Radiation research, 1991, Volume: 127, Issue:3

    Topics: Acetophenones; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Diethylcarbamazine; Ibupro

1991
Effect of indomethacin on arterial oxygenation in critically ill patients with severe bacterial pneumonia.
    Lancet (London, England), 1987, Feb-14, Volume: 1, Issue:8529

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Bacterial Infections; Critical Care; Humans; Hypoxia;

1987
Indomethacin and arterial oxygenation in critically ill patients with severe bacterial pneumonia.
    Lancet (London, England), 1987, Mar-28, Volume: 1, Issue:8535

    Topics: Arteries; Bacterial Infections; Critical Care; Humans; Indomethacin; Lung; Microcirculation; Oxygen;

1987
Inflammation and models of chronic pulmonary hypertension.
    The American review of respiratory disease, 1987, Volume: 136, Issue:3

    Topics: Animals; Endotoxins; Escherichia coli; Hypertension, Pulmonary; Indomethacin; Lung; Pneumonia; Radia

1987
Effect of cyclooxygenase blockade on gas exchange and hemodynamics in Pseudomonas pneumonia.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 63, Issue:5

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Carbon Monoxide; Dogs; Epoprostenol; Hemodynamics; Indomethac

1987
Alveolar inflammation and arachidonate metabolism in monocrotaline-induced pulmonary hypertension.
    The American journal of physiology, 1985, Volume: 248, Issue:6 Pt 2

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Aci

1985