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indomethacin and Pleural Effusion

indomethacin has been researched along with Pleural Effusion in 16 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Pleural Effusion: Presence of fluid in the pleural cavity resulting from excessive transudation or exudation from the pleural surfaces. It is a sign of disease and not a diagnosis in itself.

Research Excerpts

ExcerptRelevanceReference
"A model is described of acute inflammation in the pleural cavity of rats using calcium pyrophosphate as the irritant."7.65Calcium pyrophosphate-induced pleurisy in rats: a new model of acute inflammation. ( Capasso, F; Deporter, DA; Dunn, CJ; Giroud, JP; Willoughby, DA; Yamamoto, S, 1975)
"We evaluated the effects of a new non-steroidal anti-inflammatory drug (NSAID), d-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid (M-5011), and indomethacin on the production of arachidonate metabolites and pro-inflammatory cytokines in male Sprague-Dawley rats with monosodium urate crystal (MSU)-induced pleurisy."3.70Effect of a novel non-steroidal anti-inflammatory drug (M-5011) on cytokine levels in rats with monosodium urate crystal- induced pleurisy. ( Aihara, S; Iwata, K; Murakami, N; Naruse, T; Saito, T, 1999)
"A model is described of acute inflammation in the pleural cavity of rats using calcium pyrophosphate as the irritant."3.65Calcium pyrophosphate-induced pleurisy in rats: a new model of acute inflammation. ( Capasso, F; Deporter, DA; Dunn, CJ; Giroud, JP; Willoughby, DA; Yamamoto, S, 1975)
"One patient had ulcerative colitis, while two patients had Crohn's disease."1.27Pleuropericarditis: an extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature. ( Brewster, AC; Darrah, JJ; Heilpern, RJ; Patwardhan, RV, 1983)
"Pleurisy was induced by intrapleural injection of 1 ug of AGEPC into rats."1.27Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats. ( Hayashi, M; Oh, S; Yamaki, K, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199012 (75.00)18.7374
1990's3 (18.75)18.2507
2000's1 (6.25)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Walsh, DA1
Shamblee, DA1
Welstead, WJ1
Sancilio, LF3
Dalmarco, EM1
Budni, P1
Parisotto, EB1
Wilhelm Filho, D1
Fröde, TS1
Burrows, FG1
Birnie, JH1
Sutton, BM1
Zuccarello, M1
Rush, JA1
Lo, TN1
Almeida, AP1
Beaven, MA1
Patwardhan, RV1
Heilpern, RJ1
Brewster, AC1
Darrah, JJ1
Buick, RN1
Fry, SE1
Salmon, SE1
Kakutani, M1
Murakami, M1
Okamoto, H1
Kudo, I1
Inoue, K1
Murray, HG1
Stone, PR1
Strand, L1
Flower, J1
Murakami, N1
Aihara, S1
Iwata, K1
Saito, T1
Naruse, T1
Willoughby, DA1
Dunn, CJ1
Yamamoto, S1
Capasso, F1
Deporter, DA1
Giroud, JP1
Oh, S1
Hayashi, M1
Yamaki, K1
Migueres, J1
Jover, A1
Vetillard, R1
Amigues, H1
Gire, JL1
Martino, A1
De Risi, F1
Faiella, F1
Rodriguez, R1

Other Studies

16 other studies available for indomethacin and Pleural Effusion

ArticleYear
Antiinflammatory agents. 2. Syntheses and antiinflammatory activity of substituted 2-aminophenylacetic acid derivatives.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cattle; Chemical Phenomena; Chemistry; Cyclooxygenas

1982
Antioxidant effects of mycophenolate mofetil in a murine pleurisy model.
    Transplant immunology, 2009, Volume: 22, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Catalase; Cell Count; Cell Movement;

2009
Pulmonary nodules in rheumatoid disease: a report of two cases.
    The British journal of radiology, 1967, Volume: 40, Issue:472

    Topics: Arthritis, Rheumatoid; Humans; Indomethacin; Lung Diseases; Male; Middle Aged; Pleural Effusion; Pne

1967
Some anti-inflammatory properties of 8-trifluoromethylphenothiazine-1-carboxylic acid (SK & F 22908).
    Medicina et pharmacologia experimentalis. International journal of experimental medicine, 1967, Volume: 17, Issue:1

    Topics: Animals; Erythema; Flufenamic Acid; Granuloma; Guinea Pigs; Indomethacin; Male; Phenothiazines; Phen

1967
Effect of indomethacin on generation of chemotactic activity in inflammatory exudates induced by carrageenan.
    European journal of pharmacology, 1984, Mar-16, Volume: 99, Issue:1

    Topics: Animals; Blood Proteins; Carrageenan; Chemotactic Factors; Chemotaxis, Leukocyte; Complement C5; Exu

1984
Pleuropericarditis: an extraintestinal complication of inflammatory bowel disease. Report of three cases and review of literature.
    Archives of internal medicine, 1983, Volume: 143, Issue:1

    Topics: Adult; Aspirin; Colitis, Ulcerative; Crohn Disease; Humans; Indomethacin; Male; Middle Aged; Pericar

1983
Effect of host-cell interactions on clonogenic carcinoma cells in human malignant effusions.
    British journal of cancer, 1980, Volume: 41, Issue:5

    Topics: Ascitic Fluid; Carcinoma; Cell Adhesion; Cell Count; Cell Fractionation; Clone Cells; Female; Hemato

1980
Role of type II phospholipase A2 in the inflammatory process of carrageenan-induced pleurisy in rats.
    FEBS letters, 1994, Feb-14, Volume: 339, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Carrageenan; Indomethacin; Inflammation; Male; Phospholipases A; Ph

1994
Fetal pleural effusion following maternal indomethacin therapy.
    British journal of obstetrics and gynaecology, 1993, Volume: 100, Issue:3

    Topics: Adult; Cesarean Section; Diseases in Twins; Female; Fetal Diseases; Humans; Indomethacin; Pleural Ef

1993
Effect of a novel non-steroidal anti-inflammatory drug (M-5011) on cytokine levels in rats with monosodium urate crystal- induced pleurisy.
    Japanese journal of pharmacology, 1999, Volume: 79, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Cytokines; Dinoprostone; Exudates and T

1999
Calcium pyrophosphate-induced pleurisy in rats: a new model of acute inflammation.
    Agents and actions, 1975, Volume: 5, Issue:1

    Topics: Animals; Calcium Phosphates; Cyclic AMP; Diphosphates; Disease Models, Animal; Indomethacin; Inflamm

1975
Inflammatory effects of acetylglycerylether phosphorylcholine: vascular permeability increase and induction of pleurisy in rats.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 22, Issue:1

    Topics: Animals; Azo Compounds; Bradykinin; Capillary Permeability; Dexamethasone; Guinea Pigs; Histamine; I

1986
[Pleurisy in chronic rheumatoid polyarthritis (apropos of 4 cases)].
    Marseille medical, 1972, Volume: 109, Issue:3

    Topics: Antimalarials; Arthritis, Rheumatoid; Humans; Indomethacin; Male; Middle Aged; Pleural Effusion; Ple

1972
[Preliminary results of the therapeutic use of a non-steroid anti-inflammatory agent in tubercular pathology].
    Minerva medica, 1968, Feb-17, Volume: 59, Issue:14

    Topics: Adolescent; Adult; Aged; Child; Female; Humans; Indomethacin; Male; Middle Aged; Peritonitis; Pleura

1968
Evans blue-carrageenan pleural effusion as a model for the assay of nonsteroidal antirheumatic drugs.
    The Journal of pharmacology and experimental therapeutics, 1969, Volume: 168, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Arthritis; Aspirin; Carrageenan; Chloroquine; Coloring Agents; Ed

1969
Effect of non-steroidal anti-inflammatory drugs in the Evans Blue pleural effusion.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 123, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Aspirin; Coloring Agents; Flufenamic Acid; Indomethacin; Mefenami

1966