indomethacin has been researched along with Plasma Cell Tumor in 9 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Continuous indomethacin (INDO) administration in the drinking water (10 to 20 microg/mL) profoundly inhibited plasmacytoma (PCT) development initiated by three 0." | 7.69 | Indomethacin is a potent inhibitor of pristane and plastic disc induced plasmacytomagenesis in a hypersusceptible BALB/c congenic strain. ( Jones, GM; Potter, M; Wax, J, 1997) |
| "In BALB/cAnPt (BALB/c) mice, the intraperitoneal injection of pristane induces the formation of chronic oil granulomatous tissue and a high incidence of plasmacytomas (PCT)." | 7.68 | Pristane induces an indomethacin inhibitable inflammatory influx of CD4+ T cells and IFN-gamma production in plasmacytoma-susceptible BALB/cAnPt mice. ( Degrassi, A; McDonald, AH, 1993) |
| "Indomethacin given continuously in the drinking water (20 micrograms/ml) to BALB/cAn pi mice during the latent period of pristane-induced plasmacytoma development dramatically reduced the plasmacytoma incidence from 34." | 7.67 | Inhibition of plasmacytoma development in BALB/c mice by indomethacin. ( Anderson, AO; Nordan, RP; Potter, M; Wax, JS, 1985) |
| "Continuous indomethacin (INDO) administration in the drinking water (10 to 20 microg/mL) profoundly inhibited plasmacytoma (PCT) development initiated by three 0." | 3.69 | Indomethacin is a potent inhibitor of pristane and plastic disc induced plasmacytomagenesis in a hypersusceptible BALB/c congenic strain. ( Jones, GM; Potter, M; Wax, J, 1997) |
| "In BALB/cAnPt (BALB/c) mice, the intraperitoneal injection of pristane induces the formation of chronic oil granulomatous tissue and a high incidence of plasmacytomas (PCT)." | 3.68 | Pristane induces an indomethacin inhibitable inflammatory influx of CD4+ T cells and IFN-gamma production in plasmacytoma-susceptible BALB/cAnPt mice. ( Degrassi, A; McDonald, AH, 1993) |
| "Indomethacin given continuously in the drinking water (20 micrograms/ml) to BALB/cAn pi mice during the latent period of pristane-induced plasmacytoma development dramatically reduced the plasmacytoma incidence from 34." | 3.67 | Inhibition of plasmacytoma development in BALB/c mice by indomethacin. ( Anderson, AO; Nordan, RP; Potter, M; Wax, JS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (44.44) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Auletta, M | 1 |
| Usberti, M | 1 |
| Antoniello, S | 1 |
| Stanziale, P | 1 |
| McDonald, AH | 1 |
| Degrassi, A | 1 |
| Pauels, HG | 1 |
| Specht, C | 1 |
| Becker, C | 1 |
| Kölsch, E | 1 |
| Potter, M | 4 |
| Wax, J | 1 |
| Jones, GM | 1 |
| Kutkat, L | 1 |
| Nakano, K | 1 |
| Okugawa, K | 1 |
| Furuichi, H | 1 |
| Matsui, Y | 1 |
| Sohmura, Y | 1 |
| Wax, JS | 1 |
| Anderson, AO | 1 |
| Nordan, RP | 1 |
| Marcolongo, R | 1 |
| Bianco, G | 1 |
| Di Paolo, N | 1 |
| Bravi, A | 1 |
2 reviews available for indomethacin and Plasma Cell Tumor
| Article | Year |
|---|---|
Inhibition of pristane-induced peritoneal plasmacytoma formation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Carcinogens; Indomethacin; Interleu | 1999 |
Indomethacin inhibition of pristane plasmacytomagenesis in genetically susceptible inbred mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Colon; Indomethacin; Mice; Mice, Inbr | 1999 |
7 other studies available for indomethacin and Plasma Cell Tumor
| Article | Year |
|---|---|
[Membranoproliferative glomerulonephritis as an unusual initial manifestation in a case of plasmacytoma].
Topics: Bence Jones Protein; Glomerulonephritis; Humans; Indomethacin; Male; Middle Aged; Plasmacytoma; Pulm | 1984 |
Pristane induces an indomethacin inhibitable inflammatory influx of CD4+ T cells and IFN-gamma production in plasmacytoma-susceptible BALB/cAnPt mice.
Topics: Animals; CD4 Antigens; Indomethacin; Inflammation; Interferon-gamma; Interleukin-5; Mice; Mice, Inbr | 1993 |
Suppression of tumour-specific cytotoxic T-cell responses against the syngeneic BALB/c plasmacytoma ADJ-PC-5 by tumour-induced CD8+ regulatory T cells via IFN-gamma.
Topics: Animals; Antibodies, Monoclonal; Ascitic Fluid; Cell Division; Cytotoxicity, Immunologic; Female; Im | 1996 |
Indomethacin is a potent inhibitor of pristane and plastic disc induced plasmacytomagenesis in a hypersusceptible BALB/c congenic strain.
Topics: Administration, Oral; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Drug Antagonism | 1997 |
Augmentation of the generation of cytotoxic T lymphocytes against syngeneic tumor cells by recombinant human tumor necrosis factor.
Topics: Animals; Antigens, Differentiation, T-Lymphocyte; Biological Factors; Cytokines; Cytotoxicity, Immun | 1989 |
Inhibition of plasmacytoma development in BALB/c mice by indomethacin.
Topics: Animals; Arthritis; Ascitic Fluid; Carcinogens; Female; Granuloma; Indomethacin; Mice; Mice, Inbred | 1985 |
[Clinical research on the antipyretic effects of indomethacin in systemic hemopathies].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Anemia, Aplastic; Antibiotics, Antineoplastic; Ant | 1970 |