indomethacin has been researched along with Placental Insufficiency in 1 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
Placental Insufficiency: Failure of the PLACENTA to deliver an adequate supply of nutrients and OXYGEN to the FETUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "When indomethacin was used to inhibit prostaglandin synthesis, placental vascular resistance did not increase, placental blood flow did not decrease, and fetal blood gases remained at normal prebypass levels during and after fetal cardiac bypass." | 1.28 | Prostaglandin synthesis inhibition prevents placental dysfunction after fetal cardiac bypass. ( Assad, RS; Hanley, FL; Sabik, JF, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sabik, JF | 1 |
| Assad, RS | 1 |
| Hanley, FL | 1 |
1 other study available for indomethacin and Placental Insufficiency
| Article | Year |
|---|---|
Prostaglandin synthesis inhibition prevents placental dysfunction after fetal cardiac bypass.
Topics: Analysis of Variance; Animals; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Female; Fetus; I | 1992 |