Page last updated: 2024-10-29

indomethacin and Pituitary Neoplasms

indomethacin has been researched along with Pituitary Neoplasms in 11 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Pituitary Neoplasms: Neoplasms which arise from or metastasize to the PITUITARY GLAND. The majority of pituitary neoplasms are adenomas, which are divided into non-secreting and secreting forms. Hormone producing forms are further classified by the type of hormone they secrete. Pituitary adenomas may also be characterized by their staining properties (see ADENOMA, BASOPHIL; ADENOMA, ACIDOPHIL; and ADENOMA, CHROMOPHOBE). Pituitary tumors may compress adjacent structures, including the HYPOTHALAMUS, several CRANIAL NERVES, and the OPTIC CHIASM. Chiasmal compression may result in bitemporal HEMIANOPSIA.

Research Excerpts

ExcerptRelevanceReference
"Headache is a common problem in patients with pituitary tumours."1.32Prolactinomas, dopamine agonists and headache: two case reports. ( Goadsby, PJ; Levy, MJ; Matharu, MS, 2003)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19908 (72.73)18.7374
1990's1 (9.09)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grangeon, L1
Moscatelli, L1
Zanin, A1
Rouille, A1
Maltete, D1
Guegan-Massardier, E1
Levy, MJ1
Matharu, MS1
Goadsby, PJ1
Heisler, S1
Kolesnick, RN1
Musacchio, I1
Thaw, C1
Gershengorn, MC1
Jones, TH1
Kennedy, RL1
Justice, SK1
Price, A1
Koike, K1
Judd, AM1
Login, IS1
Yasumoto, T1
MacLeod, RM1
Vacher, P1
McKenzie, J1
Dufy, B1
Kasperlik-ZaƂuska, A1
Jeske, W1
Migdalska, B1
Jastrzebska, H1
Huang, YS1
Falardeau, P1
Martineau, A1
Nestruck, AC1
Davignon, J1
Fujii, T1
Misumi, S1
Takeda, F1
Hertelendy, F1
Keay, L1

Other Studies

11 other studies available for indomethacin and Pituitary Neoplasms

ArticleYear
Indomethacin-Responsive Paroxysmal Hemicrania in an Elderly Man: An Unusual Presentation of Pituitary Apoplexy.
    Headache, 2017, Volume: 57, Issue:10

    Topics: Adenoma; Aged; Cyclooxygenase Inhibitors; Humans; Indomethacin; Male; Paroxysmal Hemicrania; Pituita

2017
Prolactinomas, dopamine agonists and headache: two case reports.
    European journal of neurology, 2003, Volume: 10, Issue:2

    Topics: Adult; Amenorrhea; Anti-Inflammatory Agents, Non-Steroidal; Bromocriptine; Cabergoline; Dopamine Ago

2003
12-O-tetradecanoyl-phorbol-13-acetate-induced ACTH secretion in pituitary tumor cells.
    European journal of pharmacology, 1984, Feb-17, Volume: 98, Issue:2

    Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Line; Cells, Cultured; Cyclic AMP; Dexamethasone

1984
Arachidonic acid mobilizes calcium and stimulates prolactin secretion from GH3 cells.
    The American journal of physiology, 1984, Volume: 246, Issue:5 Pt 1

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Calcium Radi

1984
Interleukin-1 stimulates the release of interleukin-6 from cultured human pituitary adenoma cells.
    Acta endocrinologica, 1993, Volume: 128, Issue:5

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Dinoprostone; Drug Interactions; Female; Growth H

1993
Maitotoxin, a calcium channel activator, increases prolactin release from rat pituitary tumor 7315a cells by a mechanism that may involve leukotriene production.
    Neuroendocrinology, 1986, Volume: 43, Issue:3

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Calcium; Cell Line; Indomethacin; Ion Channels; Marine

1986
Arachidonic acid affects membrane ionic conductances of GH3 pituitary cells.
    The American journal of physiology, 1989, Volume: 257, Issue:2 Pt 1

    Topics: Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Cell Membrane; Electric Conductivity; Indom

1989
Failure of indomethacin to suppress plasma adrenocorticotropin levels and beta-endorphin-like immunoreactivity in Nelson's syndrome.
    Endokrynologia Polska, 1987, Volume: 38, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Female; Humans; Indomethacin; Male; Middle Aged;

1987
Effect of indomethacin treatment on prostaglandin excretion and tissue phospholipid fatty acid composition in rats bearing mammotropic pituitary tumor, MtT-F4.
    Prostaglandins, leukotrienes, and medicine, 1986, Volume: 23, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Epoprostenol; Fatty Acids; Indomethacin; Kidney; Liver; Male;

1986
Management of polyuria subsequent to pituitary surgery based on the diurnal pattern of urinary excretion.
    Surgical neurology, 1985, Volume: 23, Issue:1

    Topics: Adenoma; Adolescent; Adult; Aged; Circadian Rhythm; Diabetes Insipidus; Female; Humans; Indomethacin

1985
Studies on growth homone secretion. VI. Effects of dibutyryl cyclic AMP, prostaglandin E1, and indomethacin on growth and hormone secretion by rat pituitary tumor cells in culture.
    Prostaglandins, 1974, May-10, Volume: 6, Issue:3

    Topics: Animals; Bucladesine; Cell Division; Cell Line; Cell Survival; Cells, Cultured; Cyclic AMP; Depressi

1974