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indomethacin and Peritoneal Carcinomatosis

indomethacin has been researched along with Peritoneal Carcinomatosis in 8 studies

Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.

Research Excerpts

ExcerptRelevanceReference
" The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers."7.67[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987)
"We investigated the antitumor effects of a synthetic lipid A derivative, DT-5461a, in combination with indomethacin in three experimental tumor models (peritoneal carcinomatosis, liver tumor, and lung tumor models) of transplanted colon 26 carcinoma in mice."3.69Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice. ( Akimoto, T; Jimbo, T; Tohgo, A, 1995)
" The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers."3.67[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's4 (50.00)18.2507
2000's1 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kinugasa, S1
Smith, E1
Drew, PA1
Watson, DI1
Jamieson, GG1
Metzger, U1
Meier, J1
Uhlschmid, G1
Weihe, H1
Warshaw, AL1
Carey, RW1
Robinson, DR1
Jimbo, T1
Akimoto, T1
Tohgo, A1
Pauels, HG1
Specht, C1
Becker, C1
Kölsch, E1
Potter, M2
Kutkat, L1
Narisawa, T1
Takahashi, M1
Masuda, T1
Nagasawa, O1
Koyama, H1

Reviews

2 reviews available for indomethacin and Peritoneal Carcinomatosis

ArticleYear
Inhibition of pristane-induced peritoneal plasmacytoma formation.
    Current topics in microbiology and immunology, 1999, Volume: 246

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Carcinogens; Indomethacin; Interleu

1999
Indomethacin inhibition of pristane plasmacytomagenesis in genetically susceptible inbred mice.
    Advances in experimental medicine and biology, 1999, Volume: 469

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Colon; Indomethacin; Mice; Mice, Inbr

1999

Other Studies

6 other studies available for indomethacin and Peritoneal Carcinomatosis

ArticleYear
Aspirin and indomethacin for the prevention of experimental port-site metastases.
    Surgical endoscopy, 2004, Volume: 18, Issue:5

    Topics: Animals; Aspirin; Cell Proliferation; Indomethacin; Laparoscopy; Neoplasm Seeding; Peritoneal Neopla

2004
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
    Diseases of the colon and rectum, 1984, Volume: 27, Issue:6

    Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating

1984
Control of fever associated with visceral cancers by indomethacin.
    Surgery, 1981, Volume: 89, Issue:4

    Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas

1981
Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice.
    Cancer immunology, immunotherapy : CII, 1995, Volume: 40, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dinoprostone; Disacchari

1995
Suppression of tumour-specific cytotoxic T-cell responses against the syngeneic BALB/c plasmacytoma ADJ-PC-5 by tumour-induced CD8+ regulatory T cells via IFN-gamma.
    Scandinavian journal of immunology, 1996, Volume: 43, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Ascitic Fluid; Cell Division; Cytotoxicity, Immunologic; Female; Im

1996
[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1987, Volume: 14, Issue:8

    Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Dinoprostone; D

1987