indomethacin has been researched along with Peritoneal Carcinomatosis in 8 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 7.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| "We investigated the antitumor effects of a synthetic lipid A derivative, DT-5461a, in combination with indomethacin in three experimental tumor models (peritoneal carcinomatosis, liver tumor, and lung tumor models) of transplanted colon 26 carcinoma in mice." | 3.69 | Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice. ( Akimoto, T; Jimbo, T; Tohgo, A, 1995) |
| " The anti-tumor activity of indomethacin was investigated in CDF1 mice (BALB/c X DBA/2) implanted intraperitoneally with mouse colon adenocarcinoma 26 (5 X 10(5) or 2 X 10(5) cells) in a model study to prevent peritoneal recurrence after surgery for gastrointestinal cancers." | 3.67 | [Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin]. ( Koyama, H; Masuda, T; Nagasawa, O; Narisawa, T; Takahashi, M, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 4 (50.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kinugasa, S | 1 |
| Smith, E | 1 |
| Drew, PA | 1 |
| Watson, DI | 1 |
| Jamieson, GG | 1 |
| Metzger, U | 1 |
| Meier, J | 1 |
| Uhlschmid, G | 1 |
| Weihe, H | 1 |
| Warshaw, AL | 1 |
| Carey, RW | 1 |
| Robinson, DR | 1 |
| Jimbo, T | 1 |
| Akimoto, T | 1 |
| Tohgo, A | 1 |
| Pauels, HG | 1 |
| Specht, C | 1 |
| Becker, C | 1 |
| Kölsch, E | 1 |
| Potter, M | 2 |
| Kutkat, L | 1 |
| Narisawa, T | 1 |
| Takahashi, M | 1 |
| Masuda, T | 1 |
| Nagasawa, O | 1 |
| Koyama, H | 1 |
2 reviews available for indomethacin and Peritoneal Carcinomatosis
| Article | Year |
|---|---|
Inhibition of pristane-induced peritoneal plasmacytoma formation.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; B-Lymphocytes; Carcinogens; Indomethacin; Interleu | 1999 |
Indomethacin inhibition of pristane plasmacytomagenesis in genetically susceptible inbred mice.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carcinogens; Colon; Indomethacin; Mice; Mice, Inbr | 1999 |
6 other studies available for indomethacin and Peritoneal Carcinomatosis
| Article | Year |
|---|---|
Aspirin and indomethacin for the prevention of experimental port-site metastases.
Topics: Animals; Aspirin; Cell Proliferation; Indomethacin; Laparoscopy; Neoplasm Seeding; Peritoneal Neopla | 2004 |
Influence of various prostaglandin synthesis inhibitors on DMH-induced rat colon cancer.
Topics: 1,2-Dimethylhydrazine; Animals; Body Weight; Colonic Neoplasms; Dimethylhydrazines; Drinking; Eating | 1984 |
Control of fever associated with visceral cancers by indomethacin.
Topics: Abdominal Neoplasms; Adenocarcinoma; Adult; Aged; Female; Fever; Humans; Indomethacin; Liver Neoplas | 1981 |
Effect of combined administration of a synthetic low-toxicity lipid A derivative, DT-5461a, and indomethacin in various experimental tumor models of colon 26 carcinoma in mice.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Colonic Neoplasms; Dinoprostone; Disacchari | 1995 |
Suppression of tumour-specific cytotoxic T-cell responses against the syngeneic BALB/c plasmacytoma ADJ-PC-5 by tumour-induced CD8+ regulatory T cells via IFN-gamma.
Topics: Animals; Antibodies, Monoclonal; Ascitic Fluid; Cell Division; Cytotoxicity, Immunologic; Female; Im | 1996 |
[Prevention of peritoneal carcinomatosis recurrence with a prostaglandin synthesis inhibitor, indomethacin].
Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Colonic Neoplasms; Dinoprostone; D | 1987 |