indomethacin has been researched along with Peripheral Nerve Diseases in 5 studies
Indomethacin: A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
indometacin : A member of the class of indole-3-acetic acids that is indole-3-acetic acid in which the indole ring is substituted at positions 1, 2 and 5 by p-chlorobenzoyl, methyl, and methoxy groups, respectively. A non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The mechanism underpinning pain relief induced by the GlyT2 inhibitor at 10 mg/kg is likely due to increased glycinergic inhibition in the lumbar spinal cord, although the bell-shaped dose-response curve warrants further translational considerations." | 1.62 | Assessment of the Anti-Allodynic and Anti-Hyperalgesic Efficacy of a Glycine Transporter 2 Inhibitor Relative to Pregabalin, Duloxetine and Indomethacin in a Rat Model of Cisplatin-Induced Peripheral Neuropathy. ( Corradini, L; Kuo, A; Nicholson, JR; Smith, MT, 2021) |
| "Hyperalgesia was detected 2 h after nerve transection and persisted for 64 days." | 1.35 | The analgesic effect of crotoxin on neuropathic pain is mediated by central muscarinic receptors and 5-lipoxygenase-derived mediators. ( Amorim, RL; Brigatte, P; Conceição, IM; Cury, Y; Della-Casa, MS; Ferreira, WA; Gutierrez, VP; Nicoletti, JL; Nogueira-Neto, Fde S; Picolo, G; Takahira, RK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuo, A | 1 |
| Corradini, L | 1 |
| Nicholson, JR | 1 |
| Smith, MT | 1 |
| Nogueira-Neto, Fde S | 1 |
| Amorim, RL | 1 |
| Brigatte, P | 1 |
| Picolo, G | 1 |
| Ferreira, WA | 1 |
| Gutierrez, VP | 1 |
| Conceição, IM | 1 |
| Della-Casa, MS | 1 |
| Takahira, RK | 1 |
| Nicoletti, JL | 1 |
| Cury, Y | 1 |
| Nakano, M | 1 |
| Matsui, H | 1 |
| Miaki, K | 1 |
| Tsuji, H | 1 |
| Eade, OE | 1 |
| Acheson, ED | 1 |
| Cuthbert, MF | 1 |
| Hawkes, CH | 1 |
| Denault, A | 1 |
| Dimopoulos, MA | 1 |
| Fitzcharles, MA | 1 |
5 other studies available for indomethacin and Peripheral Nerve Diseases
| Article | Year |
|---|---|
Assessment of the Anti-Allodynic and Anti-Hyperalgesic Efficacy of a Glycine Transporter 2 Inhibitor Relative to Pregabalin, Duloxetine and Indomethacin in a Rat Model of Cisplatin-Induced Peripheral Neuropathy.
Topics: Analgesics; Animals; Benzamides; Cisplatin; Disease Models, Animal; Dose-Response Relationship, Drug | 2021 |
The analgesic effect of crotoxin on neuropathic pain is mediated by central muscarinic receptors and 5-lipoxygenase-derived mediators.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygen | 2008 |
Postlaminectomy adhesion of the cauda equina. Inhibitory effects of anti-inflammatory drugs on cauda equina adhesion in rats.
Topics: Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arachnoiditis; Cauda Equ | 1998 |
Peripheral neuropathy and indomethacin.
Topics: Aged; Arthritis, Rheumatoid; Female; Humans; Indomethacin; Male; Middle Aged; Movement; Peripheral N | 1975 |
Meningoencephalitis and peripheral neuropathy complicating adult Still's disease.
Topics: Adult; Arthritis, Juvenile; Aspirin; Female; Humans; Indomethacin; Meningoencephalitis; Peripheral N | 1990 |